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  • Gary Desir

    Chair, Internal Medicine

    Gary Desir M.D. is the Beeson Professor of Medicine at the Yale University School of Medicine (YSM) and serves as chair of the Department of Internal Medicine at YSM, and chair of the board of Yale Medicine.

     He is a physician-scientist whose work has been funded by the National Science Foundation, National Institute of Health, Department of Veterans Affairs, American Heart Association, and the Robert Wood Johnson foundation. His major contributions to science include the discovery a specific voltage-gated potassium channel that regulates body weight and insulin sensitivity, and the identification of a new growth factor, which he named renalase. He elucidated the pathway through which renalase affects cellular signaling and discovered that the protein can function abnormally and facilitate the development of certain cancers. Hi laboratory is currently focused on developing drugs that can treat cancer by blocking the action of renalase in cancer cells. Dr. Desir is a named inventor on several patents related to the discovery and therapeutic use of renalase, and the development of drugs that modulate renalase signaling in cancer. He is the scientific founder of 2 biotechnology companies focused on developing renalase-based therapies.

    Dr. Desir, the first person of African descent to be appointed as chair of a department at YSM, has a strong interest in issues of diversity and social justice. He is the co-founder of the minority organization for retention and expansion (MORE), a faculty group at YSM focused on increasing faculty diversity through mentoring programs and developing resilient social networks. In collaboration with Gordon Geballe, Associate Dean for Alumni and External Affairs at school of Forestry and Environmental Studies, he has worked with L’Hospital Albert Schweitzer in the Artibonite valley in Haiti on integrated projects designed to improve the standard of living in the valley.


    He was born in Port-Au-Prince, Haiti. After high school, he immigrated to the US to attend New York University, from which he graduated magna cum laude, with a bachelor’s degree in biology. He was elected to the Phi Beta Kappa Society, and also received New York University’s Founders Day award. Following graduation from Yale University School of Medicine (Cum Laude, Alpha Omega Alpha honor society), he trained in internal medicine and nephrology at Yale New Haven Hospital.

     Dr. Desir is married to Dr. Deborah Dyett Desir who practices rheumatology at Yale. They have four children, Carl, Matthew, Christopher and Alexandra, a granddaughter Elodie and a grandson Amari.

Vice Chairs

  • Lloyd G. Cantley

    Vice Chair, Basic Research

    C. N. H. Long Professor of Medicine (Nephrology) and Professor of Cellular And Molecular Physiology; Vice Chair, Research; Co-director of Education, Yale Center for Clinical Investigation

  • Aldo Peixoto

    Vice Chair, Quality & Safety

    Professor of Medicine (Nephrology); Vice Chair for Quality & Safety, Department of Internal Medicine; Clinical Chief, Section of Nephrology

  • Robert Soufer

    Vice Chair, Clinical Research

    Professor of Medicine (Cardiology); Vice Chair for Clinical Research, Department of Internal Medicine; Chief, Cardiovascular Medicine VACT Healthcare Systems

  • Lynn Tanoue

    Vice Chair, Clinical Affairs

    Professor of Medicine (Pulmonary); Vice Chair for Clinical Affairs, Internal Medicine; Director, Lung Cancer Screening Program

  • Vincent Quagliarello

    Vice Chair, Education & Academic Affairs

    Professor of Medicine (Infectious Diseases); Clinical Chief, Infectious Diseases; Vice Chair for Education and Academic Affairs, Department of Internal Medicine

Associate Chairs

Internal Medicine - Pediatrics Residency Program Leadership

Internal Medicine Primary Care Residency Program Leadership

Internal Medicine Traditional Residency Program Leadership