Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsNikhil Singh, MD, PhD
Assistant Professor AdjunctAbout
Research
Publications
2025
A TMPRSS6-inhibiting mAb improves disease in a β-thalassemia mouse model and reduces iron in healthy humans
Lob H, Singh N, Mohammadi K, Ivanova L, Crowell B, Kim H, Kravets L, Das N, Ray Y, Kim J, Rottey S, Labriola-Tompkins E, Hassan H, Farrelly L, Chin H, Preda M, Noakes L, Saotome K, Franklin M, Retter M, Karayusuf E, Flanagan J, Olson W, Nannuru K, Idone V, Burczynski M, Harari O, Perlee L, Van Lancker G, Murphy A, Economides A, Hatsell S. A TMPRSS6-inhibiting mAb improves disease in a β-thalassemia mouse model and reduces iron in healthy humans. JCI Insight 2025, 10: e191813. PMID: 40548380, PMCID: PMC12220967, DOI: 10.1172/jci.insight.191813.Peer-Reviewed Original Research
2021
Perianeurysmal retroperitoneal fibrosis presenting as acute kidney injury: A case report.
Hodson DZ, Cantley LG, Perincheri S, Singh N. Perianeurysmal retroperitoneal fibrosis presenting as acute kidney injury: A case report. Clinical Nephrology 2021, 96: 112-119. PMID: 34142944, DOI: 10.5414/cn110331.Peer-Reviewed Original ResearchTubular Cell Dropout in Preimplantation Deceased Donor Biopsies as a Predictor of Delayed Graft Function
Avigan ZM, Singh N, Kliegel JA, Weiss M, Moeckel GW, Cantley LG. Tubular Cell Dropout in Preimplantation Deceased Donor Biopsies as a Predictor of Delayed Graft Function. Transplantation Direct 2021, 7: e716. PMID: 34476295, PMCID: PMC8384397, DOI: 10.1097/txd.0000000000001168.Peer-Reviewed Original Research
2019
Development of a 2-dimensional atlas of the human kidney with imaging mass cytometry
Singh N, Avigan ZM, Kliegel JA, Shuch BM, Montgomery RR, Moeckel GW, Cantley LG. Development of a 2-dimensional atlas of the human kidney with imaging mass cytometry. JCI Insight 2019, 4: e129477. PMID: 31217358, PMCID: PMC6629112, DOI: 10.1172/jci.insight.129477.Peer-Reviewed Original ResearchUrine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritis
Moledina DG, Wilson FP, Pober JS, Perazella MA, Singh N, Luciano RL, Obeid W, Lin H, Kuperman M, Moeckel GW, Kashgarian M, Cantley LG, Parikh CR. Urine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritis. JCI Insight 2019, 4: e127456. PMID: 31092735, PMCID: PMC6542610, DOI: 10.1172/jci.insight.127456.Peer-Reviewed Original Research
2013
Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression
Singh N, Gupta M, Trivedi CM, Singh MK, Li L, Epstein JA. Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression. Developmental Biology 2013, 377: 333-344. PMID: 23506836, PMCID: PMC3652235, DOI: 10.1016/j.ydbio.2013.03.008.Peer-Reviewed Original Research
2011
Histone Deacetylase 3 Regulates Smooth Muscle Differentiation in Neural Crest Cells and Development of the Cardiac Outflow Tract
Singh N, Trivedi CM, Lu M, Mullican SE, Lazar MA, Epstein JA. Histone Deacetylase 3 Regulates Smooth Muscle Differentiation in Neural Crest Cells and Development of the Cardiac Outflow Tract. Circulation Research 2011, 109: 1240-1249. PMID: 21959220, PMCID: PMC3225257, DOI: 10.1161/circresaha.111.255067.Peer-Reviewed Original ResearchAdrenal MedullaAnimalsAorta, ThoracicCell DifferentiationCell LineageCell MovementDouble Outlet Right VentricleFemaleFetal HeartGene Expression Regulation, DevelopmentalHeart Defects, CongenitalHeart Septal Defects, VentricularHeart VentriclesHistone DeacetylasesMaleMiceMice, TransgenicMuscle, SmoothNeural CrestPaired Box Transcription FactorsPAX3 Transcription FactorReceptors, NotchThymus GlandWnt1 ProteinDiet-induced Lethality Due to Deletion of the Hdac3 Gene in Heart and Skeletal Muscle
Sun Z, Singh N, Mullican SE, Everett LJ, Li L, Yuan L, Liu X, Epstein JA, Lazar MA. Diet-induced Lethality Due to Deletion of the Hdac3 Gene in Heart and Skeletal Muscle. Journal Of Biological Chemistry 2011, 286: 33301-33309. PMID: 21808063, PMCID: PMC3190900, DOI: 10.1074/jbc.m111.277707.Peer-Reviewed Original Research
2007
The effect of genetic background on the function of Saccharomyces cerevisiae mlh1 alleles that correspond to HNPCC missense mutations
Wanat JJ, Singh N, Alani E. The effect of genetic background on the function of Saccharomyces cerevisiae mlh1 alleles that correspond to HNPCC missense mutations. Human Molecular Genetics 2007, 16: 445-452. PMID: 17210669, DOI: 10.1093/hmg/ddl479.Peer-Reviewed Original Research
Others
- Singh N, Tucker MJ, Rieder MJ. Mechanisms of glucocorticoid anti-inflammatory and immunosuppressive action. Review. Paediatric and Perinatal Drug Therapy, April 2005; 6 (2).Peer-Reviewed Original Research