Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsLokesh Kumar Sharma, PhD
Assistant Professor AdjunctAbout
Research
Publications
2026
Soluble Thrombomodulin Links Viremia and Mortality During COVID-19: Results From the ACTIV-4a Trial.
Zuchelkowski B, Inman K, Nouraie S, Beru N, Naqvi A, Qin S, Yeh C, Zhang Y, Shah F, Sharma L, Dela Cruz C, Zhang L, McVerry B, Morris A, Neal M, Seheult J, Kitsios G, Mellors J, Lawrence D, Kim P, Jacobs J, Bain W. Soluble Thrombomodulin Links Viremia and Mortality During COVID-19: Results From the ACTIV-4a Trial. Journal Of The American Heart Association 2026, 15: e047693. PMID: 42089155, DOI: 10.1161/jaha.125.047693.Peer-Reviewed Original ResearchVascular Endothelial Growth Factor-D Improves Lung Vascular Integrity During Acute Lung Injury
Yoon Y, Sharma L, Tang W, Kirk S, Raredon M, Ahangari F, Khoury J, Qian H, Ke Y, Tulapurkar M, Liu R, Luan Y, Yuan Q, Chen L, Birukov K, Simons M, Wu D, Niklason L, Kaminski N, Yuan Y. Vascular Endothelial Growth Factor-D Improves Lung Vascular Integrity During Acute Lung Injury. Circulation Research 2026, 138: e326094. PMID: 41822962, PMCID: PMC13007730, DOI: 10.1161/circresaha.124.326094.Peer-Reviewed Original ResearchEpidermal growth factor receptor regulates Beclin-1 in hyperoxic acute lung injury
Harris Z, Korde A, Khoury J, Manning E, Stanley G, Shin Y, Mitchell K, von der Schulenburg A, Sun Y, Hu B, Shin H, Joerns J, Clark B, Placek L, Unutmaz D, Moldobaeva A, Sharma L, Sauler M, Rajagopalan G, Zhang X, Wang H, Ghaedi M, Kang M, Koff J. Epidermal growth factor receptor regulates Beclin-1 in hyperoxic acute lung injury. BMJ Open Respiratory Research 2026, 13: e003323. PMID: 41592865, PMCID: PMC12853440, DOI: 10.1136/bmjresp-2025-003323.Peer-Reviewed Original ResearchA clinically interpretable prediction model for acute mortality in patients with pneumonia requiring mechanical ventilation
Hu H, Zu Y, Zhao L, Zhang Q, Zhou G, Xu P, Zhao A, Yin F, Sharma L, Chang D. A clinically interpretable prediction model for acute mortality in patients with pneumonia requiring mechanical ventilation. Respiratory Research 2026, 27: 126. PMID: 41731516, PMCID: PMC12980919, DOI: 10.1186/s12931-026-03581-x.Peer-Reviewed Original Research
2025
Integrative single-cell RNA and ATAC sequencing reveals the impact of chronic cigarette smoking on lung epithelial responses to influenza and hyperoxia
Cha P, Zou Z, Nouws J, Brewster R, Dela Cruz C, Sharma L, Yan X, Sauler M. Integrative single-cell RNA and ATAC sequencing reveals the impact of chronic cigarette smoking on lung epithelial responses to influenza and hyperoxia. Respiratory Research 2025, 27: 13. PMID: 41366391, PMCID: PMC12801856, DOI: 10.1186/s12931-025-03393-5.Peer-Reviewed Original ResearchA familial case of Birt–Hogg–Dubé syndrome complicated with lung cancer: a case report and literature review
Feng J, Yu Y, Liu Y, Ding Y, Mu J, Jiang R, Sharma L, Jie Z. A familial case of Birt–Hogg–Dubé syndrome complicated with lung cancer: a case report and literature review. Frontiers In Medicine 2025, 12: 1581786. PMID: 40630489, PMCID: PMC12234290, DOI: 10.3389/fmed.2025.1581786.Peer-Reviewed Original ResearchIL‐6 signaling regulates the inflammatory response without impacting pathogen burden during influenza‐associated pulmonary aspergillosis
Sharma L, Singh R, Tolman N, Ngeow C, Duray A, Naghshtabrizi N, Ahmad A, Bain W, Robinson K. IL‐6 signaling regulates the inflammatory response without impacting pathogen burden during influenza‐associated pulmonary aspergillosis. Physiological Reports 2025, 13: e70372. PMID: 40420617, PMCID: PMC12106949, DOI: 10.14814/phy2.70372.Peer-Reviewed Original ResearchProphylactic anticoagulant therapy is associated with improved survival in ICU patients with non-COVID-19 pneumonia: a retrospective cohort study
Hu H, Zhu Y, Hu R, Zhao L, Zeng X, Wu X, Qiu R, Nie Y, Sharma L, Chang D. Prophylactic anticoagulant therapy is associated with improved survival in ICU patients with non-COVID-19 pneumonia: a retrospective cohort study. Frontiers In Pharmacology 2025, 16: 1597885. PMID: 40406481, PMCID: PMC12095157, DOI: 10.3389/fphar.2025.1597885.Peer-Reviewed Original ResearchGlucagon-Like Peptide-1 Is Prognostic of Mortality in Acute Respiratory Failure
Hansell C, Aneis H, Kitsios G, Bain W, Zhao Y, Suber T, Evankovich J, Sharma L, Ramakrishnan S, Prendergast N, Hensley M, Malik S, Petro N, Patel J, Nouraie S, Dela Cruz C, Zhang Y, McVerry B, Shah F. Glucagon-Like Peptide-1 Is Prognostic of Mortality in Acute Respiratory Failure. Critical Care Explorations 2025, 7: e1247. PMID: 40126931, PMCID: PMC11936568, DOI: 10.1097/cce.0000000000001247.Peer-Reviewed Original ResearchTherapeutic JAK inhibition does not impact lung injury during viral or bacterial pneumonia in male mice
Sharma L, Singh R, Ngeow C, van der Geest R, Duray A, Tolman N, McVerry B, Dela Cruz C, Alcorn J, Bain W, Robinson K. Therapeutic JAK inhibition does not impact lung injury during viral or bacterial pneumonia in male mice. Physiological Reports 2025, 13: e70232. PMID: 39921246, PMCID: PMC11805821, DOI: 10.14814/phy2.70232.Peer-Reviewed Original Research