2016
Behavioral and Environmental Explanations of Elevated Blood Lead Levels in Immigrant Children and Children of Immigrants
Kaplowitz SA, Perlstadt H, Dziura JD, Post LA. Behavioral and Environmental Explanations of Elevated Blood Lead Levels in Immigrant Children and Children of Immigrants. Journal Of Immigrant And Minority Health 2016, 18: 979-986. PMID: 26163335, DOI: 10.1007/s10903-015-0243-8.Peer-Reviewed Original ResearchConceptsBlood lead levelsHigher blood lead levelsLead levelsElevated blood lead levelsBLLs of childrenLow blood lead levelsChildren's blood lead levelsBlock groupChildren of USHigh lead environmentBLL testsLow parental educationMichigan databaseMedicaid eligibilityRefugee childrenChildrenSingle-parent householdsMothers
2014
The Effect of Modified Ultrafiltration on Angiopoietins in Pediatric Cardiothoracic Operations
Lang SM, Syed MA, Dziura J, Rocco E, Kirshbom P, Bhandari V, Giuliano JS. The Effect of Modified Ultrafiltration on Angiopoietins in Pediatric Cardiothoracic Operations. The Annals Of Thoracic Surgery 2014, 98: 1699-1704. PMID: 25258157, PMCID: PMC4253712, DOI: 10.1016/j.athoracsur.2014.06.053.Peer-Reviewed Original ResearchConceptsIntensive care unit admissionCare unit admissionModified ultrafiltrationUnit admissionCardiopulmonary bypassAngpt-2Interleukin-8Proinflammatory mediatorsClinical benefitAngpt-2 concentrationsInterleukin-10 levelsProspective cohort studySystemic inflammatory responseChildren 18 yearsEnzyme-linked immunosorbentCohort studyAntiinflammatory mediatorsInterleukin-10Inflammatory responseAngiopoietin-2Angpt-1Cardiothoracic operationsPatient's bloodAdmissionCytokine removal
2009
Comparison of Neurocognitive Functioning in Children Previously Randomly Assigned to Intrathecal Methotrexate Compared With Triple Intrathecal Therapy for the Treatment of Childhood Acute Lymphoblastic Leukemia
Kadan-Lottick NS, Brouwers P, Breiger D, Kaleita T, Dziura J, Northrup V, Chen L, Nicoletti M, Bostrom B, Stork L, Neglia JP. Comparison of Neurocognitive Functioning in Children Previously Randomly Assigned to Intrathecal Methotrexate Compared With Triple Intrathecal Therapy for the Treatment of Childhood Acute Lymphoblastic Leukemia. Journal Of Clinical Oncology 2009, 27: 5986-5992. PMID: 19884541, PMCID: PMC2793042, DOI: 10.1200/jco.2009.23.5408.Peer-Reviewed Original ResearchMeSH KeywordsAntimetabolites, AntineoplasticAntineoplastic Combined Chemotherapy ProtocolsAttentionChildChild, PreschoolCognitionCross-Sectional StudiesCytarabineFemaleHumansHydrocortisoneInfantInjections, SpinalIntelligence TestsLinear ModelsMaleMemoryMethotrexateNeuropsychological TestsPrecursor Cell Lymphoblastic Leukemia-LymphomaPsychomotor PerformanceTime FactorsTreatment OutcomeUnited StatesConceptsAcute lymphoblastic leukemiaIT therapyIntrathecal methotrexateMethotrexate groupLymphoblastic leukemiaChildhood acute lymphoblastic leukemiaTriple intrathecal therapyPost-therapy periodLong-term neurotoxicityNeurocognitive functioningAssociation of treatmentMajority of childrenCNS prophylaxisFull-scale intelligence quotientIntrathecal therapyNeurologic eventsPsychotropic medicationsVisual-motor integrationTherapy groupAttention/concentrationNeurocognitive evaluationIndex scoreTherapyPatientsMethotrexateA comparison of neurocognitive functioning in children previously randomized to dexamethasone or prednisone in the treatment of childhood acute lymphoblastic leukemia
Kadan-Lottick NS, Brouwers P, Breiger D, Kaleita T, Dziura J, Liu H, Chen L, Nicoletti M, Stork L, Bostrom B, Neglia JP. A comparison of neurocognitive functioning in children previously randomized to dexamethasone or prednisone in the treatment of childhood acute lymphoblastic leukemia. Blood 2009, 114: 1746-1752. PMID: 19546477, PMCID: PMC2738566, DOI: 10.1182/blood-2008-12-186502.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaDexamethasone groupLymphoblastic leukemiaNeurocognitive functioningHigher event-free survival rateEvent-free survival rateCentral nervous system penetrationLong-term cognitive functioningPsychotropic drug usePrevious clinical trialsWorse neurocognitive functioningCorticosteroid RandomizationNeurocognitive toxicityPrednisone groupNeurologic complicationsClinical trialsSignificant overall differenceSurvival rateDrug useYounger ageWorse functioningOlder ageDiagnosisMultisite study
2007
A Randomized Trial to Assess the Efficacy of Point-of-Care Testing in Decreasing Length of Stay in a Pediatric Emergency Department
Hsiao AL, Santucci KA, Dziura J, Baker MD. A Randomized Trial to Assess the Efficacy of Point-of-Care Testing in Decreasing Length of Stay in a Pediatric Emergency Department. Pediatric Emergency Care 2007, 23: 457-462. PMID: 17666926, DOI: 10.1097/01.pec.0000280506.44924.de.Peer-Reviewed Original ResearchConceptsPediatric emergency departmentLength of stayEmergency departmentPOC groupTertiary hospital emergency departmentDedicated research assistantsFirst physician contactTrial of patientsPatient flowSelect pediatric patientsHospital emergency departmentCare testingEfficacy of pointMedical management decisionsPhysician contactPediatric patientsBlood workRandomized trialsED settingBlood drawPatientsInformed consentStayPOC testingSignificant decrease
2006
Wait-and-See Prescription for the Treatment of Acute Otitis Media: A Randomized Controlled Trial
Spiro DM, Tay KY, Arnold DH, Dziura JD, Baker MD, Shapiro ED. Wait-and-See Prescription for the Treatment of Acute Otitis Media: A Randomized Controlled Trial. JAMA 2006, 296: 1235-1241. PMID: 16968847, DOI: 10.1001/jama.296.10.1235.Peer-Reviewed Original ResearchConceptsAcute otitis mediaEmergency departmentAntibiotic prescriptionsOtitis mediaTreatment of AOMSevere acute otitis mediaUse of antibioticsClinical courseCommon diagnosisControlled TrialsClinical symptomsAdverse outcomesSubsequent feverAntibiotic useInterview 4Medical careUnnecessary useSP groupRoutine usePatientsPrevious trialsTrialsGroup assignmentAntibioticsOtalgiaEarly postoperative arrhythmias after pediatric cardiac surgery
Delaney JW, Moltedo JM, Dziura JD, Kopf GS, Snyder CS. Early postoperative arrhythmias after pediatric cardiac surgery. Journal Of Thoracic And Cardiovascular Surgery 2006, 131: 1296-1300. PMID: 16733160, DOI: 10.1016/j.jtcvs.2006.02.010.Peer-Reviewed Original ResearchConceptsAortic crossclamp timeEarly postoperative arrhythmiasPediatric cardiac surgeryCrossclamp timeCardiac surgeryAtrioventricular septal defectPostoperative arrhythmiasBypass timeSeptal defectRisk factorsCalcium levelsRe-entrant supraventricular tachycardiaAtrioventricular septal defect repairCardiopulmonary bypass timeJunctional ectopic tachycardiaSeptal defect repairComplete atrioventricular blockDevelopment of arrhythmiasNonarrhythmia groupsEctopic tachycardiaFrequent complicationPediatric patientsSignificant arrhythmiasAtrioventricular blockCardiopulmonary bypassAmylase‐Resistant Starch as Adjunct to Oral Rehydration Therapy in Children with Diarrhea
Raghupathy P, Ramakrishna BS, Oommen SP, Ahmed MS, Priyaa G, Dziura J, Young GP, Binder HJ. Amylase‐Resistant Starch as Adjunct to Oral Rehydration Therapy in Children with Diarrhea. Journal Of Pediatric Gastroenterology And Nutrition 2006, 42: 362-368. PMID: 16641573, DOI: 10.1097/01.mpg.0000214163.83316.41.Peer-Reviewed Original ResearchConceptsOral rehydration solutionAmylase-resistant starchGlucose-ORSDuration of diarrheaStool weightAcute diarrheaStandard treatmentFluid absorptionG-ORS groupMean stool weightIntravenous fluid therapyAcute watery diarrheaOral rehydration therapySeverity of diarrheaTreatment of diarrheaShort-chain fatty acidsColonic sodiumEvaluable dataRehydration therapyTreatment failureFluid therapyWatery diarrheaRehydration solutionIntestinal sodiumDiarrhea
2005
Utility of Bedside Bladder Ultrasound Before Urethral Catheterization in Young Children
Chen L, Hsiao AL, Moore CL, Dziura JD, Santucci KA. Utility of Bedside Bladder Ultrasound Before Urethral Catheterization in Young Children. Pediatrics 2005, 115: 108-111. PMID: 15629989, DOI: 10.1542/peds.2004-0738.Peer-Reviewed Original ResearchConceptsPediatric emergency medicine physiciansAmount of urineUrethral catheterizationEmergency medicine physiciansBedside ultrasoundSufficient urineMedicine physiciansUrban pediatric emergency departmentIntervention phasePediatric emergency departmentPediatric emergency physiciansSuccess rateObservation phaseSimple noninvasive procedureSubsequent ultrasoundBladder ultrasoundFirst catheterizationUnsuccessful proceduresUrine cultureEmergency departmentIntervention periodInvasive testingEmergency physiciansCatheterizationUncomfortable procedure
2004
Persistence of Benefits of Continuous Subcutaneous Insulin Infusion in Very Young Children With Type 1 Diabetes: A Follow-up Report
Weinzimer SA, Ahern JH, Doyle EA, Vincent MR, Dziura J, Steffen AT, Tamborlane WV. Persistence of Benefits of Continuous Subcutaneous Insulin Infusion in Very Young Children With Type 1 Diabetes: A Follow-up Report. Pediatrics 2004, 114: 1601-1605. PMID: 15574621, DOI: 10.1542/peds.2004-0092.Peer-Reviewed Original ResearchConceptsContinuous subcutaneous insulin infusionType 1 diabetesMultiple daily injectionsSubcutaneous insulin infusionSevere hypoglycemiaDaily injectionsInsulin infusionRate of SHMonths of CSIIYoung childrenEpisodes of DKAOlder pediatric patientsVery Young ChildrenPersistence of benefitHypoglycemia frequencyYounger patientsGlycemic controlPediatric patientsPump treatmentClinic databaseSafety dataEmergency treatmentAge groupsType 1DiabetesHuman Metapneumovirus and Severity of Respiratory Syncytial Virus Disease - Volume 10, Number 7—July 2004 - Emerging Infectious Diseases journal - CDC
Lazar I, Weibel C, Dziura J, Ferguson D, Landry ML, Kahn JS. Human Metapneumovirus and Severity of Respiratory Syncytial Virus Disease - Volume 10, Number 7—July 2004 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2004, 10: 1318-1320. PMID: 15324559, PMCID: PMC3323339, DOI: 10.3201/eid1007.030983.Peer-Reviewed Original ResearchCharacteristics That Distinguish Accidental From Abusive Injury in Hospitalized Young Children With Head Trauma
Bechtel K, Stoessel K, Leventhal JM, Ogle E, Teague B, Lavietes S, Banyas B, Allen K, Dziura J, Duncan C. Characteristics That Distinguish Accidental From Abusive Injury in Hospitalized Young Children With Head Trauma. Pediatrics 2004, 114: 165-168. PMID: 15231923, DOI: 10.1542/peds.114.1.165.Peer-Reviewed Original ResearchConceptsAbusive head injuryAccidental head injuryAbnormal mental statusMonths of ageUnilateral retinal hemorrhageRetinal hemorrhagesHead injuryProportion of childrenScalp hematomaMental statusHead traumaOutcome measuresSecondary outcome measuresHead injury groupSerial neurologic examinationsMain outcome measuresAbusive head traumaChild abuse specialistInjury groupEye examinationVitreous hemorrhageClinical featuresInitial presentationNeurologic examinationOphthalmoscopic examination