2018
Prevalence and characteristics of coronary microvascular dysfunction among chest pain patients in the emergency department
Safdar B, D’Onofrio G, Dziura J, Russell RR, Johnson C, Sinusas AJ. Prevalence and characteristics of coronary microvascular dysfunction among chest pain patients in the emergency department. European Heart Journal Acute Cardiovascular Care 2018, 9: 5-13. PMID: 29543037, DOI: 10.1177/2048872618764418.Peer-Reviewed Original ResearchConceptsCoronary microvascular dysfunctionCoronary artery diseaseCardiac positron emission tomography/Positron emission tomography/Chest pain patientsArtery diseaseAcute myocardial infarctionEmission tomography/Chest painMyocardial infarctionMicrovascular dysfunctionPain patientsEmergency departmentTomography/General emergency department populationLower coronary flow reserveNon-obstructive coronary arteriesPrior emergency department visitsTraditional cardiac risk factorsCardiac risk factorsModerate-risk patientsEmergency department visitsEmergency department patientsCoronary flow reserveEmergency department population
2017
Ranolazine and Microvascular Angina by PET in the Emergency Department: Results From a Pilot Randomized Controlled Trial
Safdar B, D’Onofrio G, Dziura J, Russell RR, Johnson C, Sinusas AJ. Ranolazine and Microvascular Angina by PET in the Emergency Department: Results From a Pilot Randomized Controlled Trial. Clinical Therapeutics 2017, 39: 55-63. PMID: 28081848, PMCID: PMC10345862, DOI: 10.1016/j.clinthera.2016.12.002.Peer-Reviewed Original ResearchConceptsCoronary microvascular dysfunctionCoronary flow reserveCoronary artery diseaseChest painSymptomatic patientsArtery diseasePrimary outcomeEmergency departmentNonobstructive coronary artery diseaseRb-82 positron emission tomographyEffect of ranolazineRate-pressure productEmergency department patientsQTc-prolonging drugsRobust clinical trialsPositron emission tomographyHypertensive urgencyMicrovascular anginaMicrovascular dysfunctionUnderdiagnosed causeControlled TrialsDepartment patientsHeart failureAcute symptomsPressure product
2012
Development of a scale to measure practitioner adherence to a brief intervention in the emergency department
Pantalon MV, Martino S, Dziura J, Li FY, Owens PH, Fiellin DA, O'Connor PG, D'Onofrio G. Development of a scale to measure practitioner adherence to a brief intervention in the emergency department. Journal Of Substance Use And Addiction Treatment 2012, 43: 382-388. PMID: 23021098, PMCID: PMC3661016, DOI: 10.1016/j.jsat.2012.08.011.Peer-Reviewed Original ResearchConceptsBrief Negotiation InterviewBrief interventionTwo-factor structureExcellent internal consistencyGood construct validityDiscriminant validityPredictive validityEmergency departmentExcellent inter-rater reliabilityPsychometric propertiesEight-itemConstruct validityHazardous drinkingInternal consistencyEmergency department patientsPractitioner adherenceInter-rater reliabilityDepartment patientsAdherence ScaleClinical practiceValidityInterventionSkillsAdherenceScale
2010
Tissue Doppler of Early Mitral Filling Correlates With Simulated Volume Loss in Healthy Subjects
Moore CL, Tham ET, Samuels KJ, McNamara RL, Galante NJ, Stachenfeld N, Shelley K, Dziura J, Silverman DG. Tissue Doppler of Early Mitral Filling Correlates With Simulated Volume Loss in Healthy Subjects. Academic Emergency Medicine 2010, 17: 1162-1168. PMID: 21175513, DOI: 10.1111/j.1553-2712.2010.00906.x.Peer-Reviewed Original ResearchConceptsInferior vena cavaLBNP levelsTissue DopplerHealthy subjectsVital signsPulsed-wave tissue DopplerLower body negative pressureLateral mitral annulusEmergency department patientsTissue Doppler assessmentTissue Doppler velocitiesEarly diastolic fillingAccurate noninvasive assessmentPulsed-wave spectral DopplerLate transmitralNegative pressure levelBlood pressureDepartment patientsDoppler assessmentVena cavaDiastolic fillingVolume lossCardiovascular diseaseMitral annulusFilling wave