Featured Publications
Sex Differences in the Presentation and Perception of Symptoms Among Young Patients With Myocardial Infarction
Lichtman JH, Leifheit EC, Safdar B, Bao H, Krumholz HM, Lorenze NP, Daneshvar M, Spertus JA, D'Onofrio G. Sex Differences in the Presentation and Perception of Symptoms Among Young Patients With Myocardial Infarction. Circulation 2018, 137: 781-790. PMID: 29459463, PMCID: PMC5822747, DOI: 10.1161/circulationaha.117.031650.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsFemaleHospitalizationHumansMaleMiddle AgedSex CharacteristicsST Elevation Myocardial InfarctionConceptsAcute myocardial infarctionPerception of symptomsChest painCare-seeking behaviorSymptom presentationYounger patientsMyocardial infarctionST-segment elevation acute myocardial infarctionMultivariable hierarchical logistic regressionIndex AMI hospitalizationMajority of womenHierarchical logistic regressionStress/anxietyVIRGO StudyMuscle painPatient characteristicsPredominant symptomAMI symptomsPerceive symptomsProdromal symptomsPatient interviewsHeart diseasePainAMI hospitalizationUS hospitals
2014
Sex‐ and Gender‐specific Research Priorities in Cardiovascular Resuscitation: Proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Resuscitation Research Workgroup
Wigginton JG, Perman SM, Barr GC, McGregor AJ, Miller AC, Napoli A, Safdar B, Weaver KR, Deutsch S, Kayea T, Becker L. Sex‐ and Gender‐specific Research Priorities in Cardiovascular Resuscitation: Proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Resuscitation Research Workgroup. Academic Emergency Medicine 2014, 21: 1343-1349. PMID: 25491706, PMCID: PMC6406034, DOI: 10.1111/acem.12541.Peer-Reviewed Original ResearchConceptsCardiac arrestCardiac resuscitationCardiovascular resuscitationPatient outcomesConsensus conferenceHospital cardiac arrest epidemiologyWithdrawal of careCardiovascular Outcomes ResearchSudden cardiac arrestGender-specific researchAcademic Emergency Medicine consensus conferenceDismal prognosisResuscitation drugsSex steroidsGender-specific issuesDisease processCardiopulmonary resuscitation trainingResuscitationTreatment roleEmergency medicineResuscitation trainingTemperature managementOutcomes researchOutcomesSexDifferential Survival for Men and Women from Out‐of‐hospital Cardiac Arrest Varies by Age: Results from the OPALS Study
Safdar B, Stolz U, Stiell IG, Cone DC, Bobrow BJ, deBoehr M, Dreyer J, Maloney J, Spaite DW. Differential Survival for Men and Women from Out‐of‐hospital Cardiac Arrest Varies by Age: Results from the OPALS Study. Academic Emergency Medicine 2014, 21: 1503-1511. PMID: 25491713, DOI: 10.1111/acem.12540.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overArrhythmias, CardiacCardiopulmonary ResuscitationElectric CountershockEmergency Medical ServicesFemaleGender IdentityHumansMaleMiddle AgedOdds RatioOntarioOut-of-Hospital Cardiac ArrestRegression AnalysisRisk FactorsSex CharacteristicsSex FactorsSurvival AnalysisSurvival RateTime FactorsConceptsHospital dischargeEmergency medical servicesProbability of survivalOHCA patientsOPAL studyInitial ventricular fibrillation/ventricular tachycardia rhythmMultivariable logistic regression modelAge 47 yearsAge 65 yearsHospital cardiac arrestSex-stratified regression modelsPrimary risk factorRegression modelsLogistic regression modelsFractional polynomialsOHCA populationHospital admissionSpontaneous circulationAdult OHCACardiac arrestRapid defibrillationLife Support ProgramRisk factorsFavorable outcomeOHCA survivalOrganization, Execution and Evaluation of the 2014 Academic Emergency Medicine Consensus Conference on Gender‐Specific Research in Emergency Care – An Executive Summary
Safdar B, Greenberg MR. Organization, Execution and Evaluation of the 2014 Academic Emergency Medicine Consensus Conference on Gender‐Specific Research in Emergency Care – An Executive Summary. Academic Emergency Medicine 2014, 21: 1307-1317. PMID: 25420469, PMCID: PMC4340245, DOI: 10.1111/acem.12530.Peer-Reviewed Original ResearchConceptsGender-specific researchEmergency careConsensus conferenceAcademic Emergency Medicine consensus conferencePatient outcomesConsensus-driven research agendaTrauma/injuryHealth care providersAcute careAcute conditionsAcute diseaseConsensus recommendationsIterative consensus processCare providersClinical careEmergency patientsAge 31Equitable careNominal group techniquePatient careSubstance abuseDiagnostic imagingMental healthCareGender medicineFunding Mechanisms for Gender‐specific Research: Proceedings from a Panel Discussion at the 2014 Academic Emergency Medicine Consensus Conference
Safdar B, Greenberg MR, Anise A, Brown J, Conwit R, Filart R, Scott J, Choo EK. Funding Mechanisms for Gender‐specific Research: Proceedings from a Panel Discussion at the 2014 Academic Emergency Medicine Consensus Conference. Academic Emergency Medicine 2014, 21: 1329-1333. PMID: 25413301, PMCID: PMC4278745, DOI: 10.1111/acem.12522.Peer-Reviewed Original ResearchGender‐specific Research for Emergency Diagnosis and Management of Ischemic Heart Disease: Proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Research Workgroup
Safdar B, Nagurney JT, Anise A, DeVon HA, D'Onofrio G, Hess EP, Hollander JE, Legato MJ, McGregor AJ, Scott J, Tewelde S, Diercks DB. Gender‐specific Research for Emergency Diagnosis and Management of Ischemic Heart Disease: Proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Research Workgroup. Academic Emergency Medicine 2014, 21: 1350-1360. PMID: 25413468, PMCID: PMC6402042, DOI: 10.1111/acem.12527.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseIschemic heart diseaseHeart diseaseCardiac ischemiaSymptomatic coronary artery diseaseObstructive coronary artery diseaseSex-specific pathophysiologyCoronary artery dissectionAge-matched menSex-specific riskPatient-centered outcomesPatient-provider communicationHealth care practitionersEmergency medical servicesGender-specific researchAcademic Emergency Medicine consensus conferencePerson meetingsBasic science researchArtery dissectionCardiovascular outcomesMonthly conference callsMicrovascular dysfunctionArtery diseasePatient outcomesCardiac biomarkers