2024
Reproductive Health Assessment and Reports of Fertility Counseling in Pediatric and Adolescent Patients with Sickle Cell Disease After Hematopoietic Cell Transplantation
George S, Veludhandi A, Xiang Y, Liu K, Stenger E, Arnold S, Mehta A, Schirmer D, Spencer J, Guilcher G, Bhatia M, Abraham A, Gomez-Lobo V, Krishnamurti L, Meacham L. Reproductive Health Assessment and Reports of Fertility Counseling in Pediatric and Adolescent Patients with Sickle Cell Disease After Hematopoietic Cell Transplantation. Transplantation And Cellular Therapy 2024, 30: 912.e1-912.e13. PMID: 38972510, PMCID: PMC11344653, DOI: 10.1016/j.jtct.2024.06.029.Peer-Reviewed Original ResearchHematopoietic cell transplantationSickle cell diseaseFollicle-stimulating hormone levelsPost-HCTParent-proxyConditioning regimensCell transplantationFertility counselingHormone levelsCell diseaseCyclophosphamide equivalent doseSickle cell disease patientsPremature ovarian insufficiencyElevated FSH levelsDiminished ovarian reserveAnti-Mullerian hormone levelsBone marrow stem cellsEffective method of educationGonadal hormone productionHealth Survey dataReproductive health assessmentReproductive health issuesMarrow stem cellsSibling donorOvarian insufficiency
2023
Acute myeloid leukemia: 2023 update on diagnosis, risk‐stratification, and management
Shimony S, Stahl M, Stone R. Acute myeloid leukemia: 2023 update on diagnosis, risk‐stratification, and management. American Journal Of Hematology 2023, 98: 502-526. PMID: 36594187, DOI: 10.1002/ajh.26822.Peer-Reviewed Original ResearchConceptsAcute myeloid leukemiaTherapeutic landscape of acute myeloid leukemiaPatient acute myeloid leukemiaInternational consensus classificationMalignant myeloid cellsStem cell cancerTherapeutic decision makingMarrow stem cellsCell cancerTherapeutic algorithmMyeloid leukemiaMyeloid cellsRisk stratificationWHO systemTherapeutic complexMutation profilesDisease characteristicsMolecular findingsConsensus classificationTherapeutic landscapeStem cellsRisk classificationLeukemiaIntegration of molecular analysisTrial results
2020
Transplant in aplastic anemia using combined G-CSF primed blood and bone marrow stem cells – a retrospective analysis
Ali N, Butt A, Altaf B, Adil S, Shaikh U. Transplant in aplastic anemia using combined G-CSF primed blood and bone marrow stem cells – a retrospective analysis. Hematology Transfusion And Cell Therapy 2020, 42: 63. DOI: 10.1016/j.htct.2020.09.113.Peer-Reviewed Original ResearchTransplant in Aplastic Anemia Using Combined Granulocyte Colony-Stimulating Factor Primed Blood and Bone Marrow Stem Cells: A Retrospective Analysis
Ali N, Butt A, Altaf B, Adil SN, Shaikh MU. Transplant in Aplastic Anemia Using Combined Granulocyte Colony-Stimulating Factor Primed Blood and Bone Marrow Stem Cells: A Retrospective Analysis. Transplantation Proceedings 2020, 53: 386-390. PMID: 32773285, DOI: 10.1016/j.transproceed.2020.06.035.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnemia, AplasticChildChild, PreschoolFemaleGraft vs Host DiseaseGranulocyte Colony-Stimulating FactorHematopoietic Stem Cell MobilizationHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedPeripheral Blood Stem Cell TransplantationPostoperative ComplicationsRetrospective StudiesTransplantation ConditioningYoung AdultConceptsBone marrow stem cellsAplastic anemiaMarrow stem cellsOverall survivalAntithymocyte globulinAllogeneic hematopoietic stem cell transplantHematopoietic stem cell transplantStem cellsStudy periodFrequency of GVHDHost disease (GVHD) prophylaxisStandard infection prophylaxisOnly curative optionBone marrow graftsStem cell transplantGranulocyte colony-stimulating factorColony-stimulating factorAga Khan UniversityAcute GVHDChronic GVHDConditioning regimenCurative optionTransplant outcomesAllogeneic transplantsConditioning regimens
2017
Medical Therapies for Endometriosis Differentially Inhibit Stem Cell Recruitment
Sahin Ersoy GS, Zolbin MM, Cosar E, Mamillapalli R, Taylor HS. Medical Therapies for Endometriosis Differentially Inhibit Stem Cell Recruitment. Reproductive Sciences 2017, 24: 818-823. PMID: 28256937, DOI: 10.1177/1933719116682879.Peer-Reviewed Original ResearchConceptsBone marrow-derived stem cellsMedroxyprogesterone acetateEstrogen deprivationEndometriosis lesionsStem cell recruitmentCell recruitmentLesions of endometriosisGreen fluorescent protein miceWeeks of treatmentBone marrow transplantLong-term treatmentMarrow-derived stem cellsStem cellsProgestin medroxyprogesterone acetateLong-term regressionBone marrow stem cellsStem cell engraftmentMarrow stem cellsProgestin therapyEndometriosis treatmentLesion regressionMedical therapyEndometriotic lesionsMarrow transplantC57BL/6 miceBone Marrow Stem Cell Chemotactic Activity Is Induced by Elevated CXCl12 in Endometriosis
Moridi I, Mamillapalli R, Cosar E, Ersoy GS, Taylor HS. Bone Marrow Stem Cell Chemotactic Activity Is Induced by Elevated CXCl12 in Endometriosis. Reproductive Sciences 2017, 24: 526-533. PMID: 27729562, PMCID: PMC5933203, DOI: 10.1177/1933719116672587.Peer-Reviewed Original ResearchConceptsEutopic endometriumEndometriotic lesionsChemotactic activityCXCR4 messenger RNAProtein expressionTreatment of endometriosisCXCR4 protein expressionStem cellsExpression of CXCL12CXCL12/CXCR4Transwell chamber migrationCXCL12 protein expressionEnzyme-linked immunosorbentBone marrow stem cellsBone marrow cellsMouse bone marrow stem cellsMarrow stem cellsEndometrial tissueControl endometriumGynecological disordersEndometriosisEndometriumChamber migrationCondition mediumCXCL12
2014
CLINICAL FEASIBILITY STUDY TO DETECT ANGIOGENESIS FOLLOWING BONE MARROW STEM CELL TRANSPLANTATION IN CHRONIC ISCHAEMIC HEART FAILURE
Mozid B, Holstensson M, Ben-Haim S, Martin J, Sinusas A, Hutton B, Mathur A. CLINICAL FEASIBILITY STUDY TO DETECT ANGIOGENESIS FOLLOWING BONE MARROW STEM CELL TRANSPLANTATION IN CHRONIC ISCHAEMIC HEART FAILURE. Journal Of The American College Of Cardiology 2014, 63: a902. DOI: 10.1016/s0735-1097(14)60902-5.Peer-Reviewed Original Research
2013
Stem cells and the reproductive system: Historical perspective and future directions
Duke CM, Taylor HS. Stem cells and the reproductive system: Historical perspective and future directions. Maturitas 2013, 76: 284-289. PMID: 24144960, DOI: 10.1016/j.maturitas.2013.08.012.Peer-Reviewed Original ResearchConceptsEndometrial-derived stem cellsStem cellsNumber of oocytesBone marrow stem cellsFuture therapeutic benefitMarrow stem cellsEndometrial regenerationParenchymal regenerationEndometrial tissueFertility preservationUterine disordersDerived stem cellsFetal stem cellsHuman ovaryMaternal circulationParkinson's diseaseTherapeutic benefitNovel treatmentsMultipotent stem cellsFetal cellsReproductive diseasesDiseaseDisease statesMature oocytesReproductive system
2010
Stem cells and reproduction
Du H, Taylor HS. Stem cells and reproduction. Current Opinion In Obstetrics & Gynecology 2010, 22: 235-241. PMID: 20305558, PMCID: PMC3107846, DOI: 10.1097/gco.0b013e328338c152.Peer-Reviewed Original ResearchConceptsStem cellsCause of endometriosisBone marrow transplantBone marrow stem cellsMarrow stem cellsStem cell biologyEndometrial regenerationMarrow transplantUterine disordersFetal stem cellsOrthotopic transplantationOvarian cancerMaternal circulationLive birthsEnd organsOvarian tissueFetal cellsUnderlying causeClinical potentialCell biologyMature oocytesDynamic organCell transformationNovel evidenceWomen
2009
Microvesicular-mediated gene transfer of prostate tumor markers
Renzulli J, Dooner G, Owens C, Colvin G, Dooner M, Del Tatto M, Goldstein L, Quesenberry P. Microvesicular-mediated gene transfer of prostate tumor markers. Journal Of Clinical Oncology 2009, 27: e16076-e16076. DOI: 10.1200/jco.2009.27.15_suppl.e16076.Peer-Reviewed Original ResearchHuman marrow cellsCell-specific phenotypeMarrow cellsHuman prostate cancer cellsSpecific genesTranscriptional factorsGene expressionMicrovesicle transferProstate-specific geneGenetic transferProstate cancer cellsGene assayCell typesGene transferMarrow stem cellsStem cellsTime RT-PCRTotal RNAMicrovesiclesProstate tumor cellsCancer cellsGenesCell-impermeable membraneExpressionRT-PCR
2007
Donor‐Derived Human Bone Marrow Cells Contribute to Solid Organ Cancers Developing After Bone Marrow Transplantation
Avital I, Moreira A, Klimstra D, Leversha M, Papadopoulos E, Brennan M, Downey R. Donor‐Derived Human Bone Marrow Cells Contribute to Solid Organ Cancers Developing After Bone Marrow Transplantation. Stem Cells 2007, 25: 2903-2909. PMID: 17690178, DOI: 10.1634/stemcells.2007-0409.Peer-Reviewed Original ResearchConceptsAllogeneic bone marrow transplantationSolid organ cancersBone marrow-derived stem cellsBone marrow transplantationMarrow-derived stem cellsOrgan cancersMalignant cellsMarrow transplantationStem cellsCells of donor originTotal body irradiationAberrant stem cell differentiationBone marrow cellsBone marrow stem cellsHuman bone marrow cellsMarrow stem cellsBody irradiationEpithelial malignanciesTumor cellularityDonor originMale patientsMarrow cellsHuman bone marrow-derived stem cellsHuman neoplasiaCancer carcinogenesis
2004
Plasticity of Bone Marrow–Derived Stem Cells
Grove JE, Bruscia E, Krause DS. Plasticity of Bone Marrow–Derived Stem Cells. Stem Cells 2004, 22: 487-500. PMID: 15277695, DOI: 10.1634/stemcells.22-4-487.Peer-Reviewed Original ResearchConceptsBone marrow stem cellsHematopoietic stem cellsStem cellsCell plasticityMesenchymal stem cellsStem cell plasticityGene expression profilesAdult stem cellsAdult bone marrow cellsMature lineagesAdult bone marrow stem cellsTissue of originExpression profilesMature cellsMarrow stem cellsBone marrow cellsNonhematopoietic tissuesMature phenotypePlasticityMarrow cellsCellsLineagesBone marrowPhenotypeTissueEvaluation of Hematopoietic Potential Generated by Transplantation of Muscle-Derived Stem Cells in Mice
Farace F, Prestoz L, Badaoui S, Guillier M, Haond C, Opolon P, Thomas JL, Zalc B, Vainchenker W, Turhan AG. Evaluation of Hematopoietic Potential Generated by Transplantation of Muscle-Derived Stem Cells in Mice. Stem Cells And Development 2004, 13: 83-92. PMID: 15068696, DOI: 10.1089/154732804773099281.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsB-LymphocytesBone Marrow CellsBone Marrow TransplantationCell DivisionCell LineageCell SeparationCell TransplantationChimeraFemaleFlow CytometryHematopoiesisHematopoietic Stem CellsHematopoietic SystemIn Situ Hybridization, FluorescenceKiller Cells, NaturalLeukocyte Common AntigensMaleMiceMice, Inbred C57BLMusclesPolymerase Chain ReactionSex FactorsStem CellsT-LymphocytesConceptsMarrow transplantationUse of muscleStem cellsTransplantation of musclesNatural killer cellsMarrow-derived stem cellsMuscle-derived hematopoietic stem cellsLevel of CFUMuscle-derived stem cellsMarrow stem cellsMuscle tissueMuscle transplantsKiller cellsTertiary recipientsHematopoietic chimerismMuscle graftsIrradiated miceAdult miceTransplantationHematopoietic stem cellsSecondary recipientsSimilar potencyMiceMurine muscleSerial transplantation
2003
Bone marrow stem cells contribute to repair of the ischemically injured renal tubule
Kale S, Karihaloo A, Clark PR, Kashgarian M, Krause DS, Cantley LG. Bone marrow stem cells contribute to repair of the ischemically injured renal tubule. Journal Of Clinical Investigation 2003, 112: 42-49. PMID: 12824456, PMCID: PMC162291, DOI: 10.1172/jci17856.Peer-Reviewed Original ResearchConceptsAcute tubular necrosisBone marrow stem cellsRenal tubulesMarrow stem cellsTubular necrosisRenal ischemiaTransient renal ischemiaAcute renal failureRenal tubular epithelial cellsStem cell infusionBlood urea nitrogenStem cellsTubular epithelial cellsMouse bone marrowRenal failureCell infusionHuman trialsTubular epitheliumBone marrowUrea nitrogenLin-Sca-1Adult mouse bone marrowNecrotic tubulesGreater riseEpithelial cells
1987
Effects of the mode of administration of mitomycin on tumor and marrow response and on the therapeutic ratio.
Rockwell S, Nierenburg M, Irvin C. Effects of the mode of administration of mitomycin on tumor and marrow response and on the therapeutic ratio. Journal Of The National Cancer Institute 1987, 71: 927-34. PMID: 3652056.Peer-Reviewed Original ResearchConceptsDoses of mitomycinTherapeutic ratioSingle injectionDaily injectionsAntineoplastic effectsSurvival curvesEMT6 mouse mammary tumorsHost toxicityBALB/c miceLarge single doseTumor growth assaysEffect of mitomycinLess host toxicityMouse mammary tumorsResponse of tumorsBone marrow stem cellsMode of administrationMarrow stem cellsSublethal lesionsMarrow responseDaily fractionsSingle doseTumor responseC miceClinical impression
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