2025
The role of long non-coding ribonucleic acid HOXA11-AS in endometriosis therapy
Mamillapalli R, Gawde N, Fay M, Atwani R, Moridi I, Taylor H. The role of long non-coding ribonucleic acid HOXA11-AS in endometriosis therapy. Reproductive Biology And Endocrinology 2025, 23: 83. PMID: 40457415, PMCID: PMC12128536, DOI: 10.1186/s12958-025-01420-0.Peer-Reviewed Original ResearchConceptsHOXA11-ASHOXA11-AS expressionEutopic endometriumLong non-coding RNAsEctopic endometriotic lesionsEndometriotic cell linesInvasion of endometriosisEndometrial stromal cellsReal-time polymerase chain reactionNon-coding RNAsEndometriotic lesionsEndometriosis therapyEndometriosis patientsNormal endometriumProgestin responsivenessEndometrial developmentTreatment responsePolymerase chain reactionQuantitative real-time polymerase chain reactionEndometriosisEndometriosis treatmentMethodsTissue samplesStromal cellsPotential target genesEndometrium
2021
81. Medical management of endometriosis in adolescent women: a review of 91 cases of biopsy-confirmed endometriosis
Li H, Cho Y, Taylor H, Vash-Margita A. 81. Medical management of endometriosis in adolescent women: a review of 91 cases of biopsy-confirmed endometriosis. Journal Of Pediatric And Adolescent Gynecology 2021, 34: 271-272. DOI: 10.1016/j.jpag.2021.02.085.Peer-Reviewed Original ResearchBiopsy-proven endometriosisOral contraceptivesLNG-IUDOral progestinCurrent treatmentYounger patientsInitial treatmentRetrospective medical record reviewCurrent hormonal treatmentsTertiary hospital systemICD-9/10 codesCommon initial treatmentMedical record reviewReproductive-aged womenCommon treatment modalityInstitutional review boardYoung adult femalesPelvic painEndometriosis treatmentInitial presentationOptimal regimensBackground EndometriosisMedical managementRecord reviewTreatment course
2019
Serum MicroRNA Biomarkers Regulated by Simvastatin in a Primate Model of Endometriosis
Cosar E, Mamillapalli R, Moridi I, Duleba A, Taylor HS. Serum MicroRNA Biomarkers Regulated by Simvastatin in a Primate Model of Endometriosis. Reproductive Sciences 2019, 26: 1343-1350. PMID: 29587611, PMCID: PMC6949973, DOI: 10.1177/1933719118765971.Peer-Reviewed Original ResearchConceptsEndometriosis groupPrimate modelSerum microRNA BiomarkersReproductive-aged womenSerum miRNA expressionTreatment of endometriosisNoninvasive diagnostic strategyMiR-150-5pNonhuman primate modelEstrogen-dependent diseaseReal-time polymerase chain reactionQuantitative real-time polymerase chain reactionTime polymerase chain reactionEndometriosis treatmentEndometriosis severitySimvastatin treatmentHuman endometriosisEndometriosisAccurate biomarkersHuman patientsMiR-451aControl expression levelsDiagnostic strategiesSpecific biomarkersSerum samplesMicroRNAs in endometriosis: biological function and emerging biomarker candidates†
Bjorkman S, Taylor HS. MicroRNAs in endometriosis: biological function and emerging biomarker candidates†. Biology Of Reproduction 2019, 101: 1167-1178. PMID: 30721951, PMCID: PMC6497525, DOI: 10.1093/biolre/ioz014.Peer-Reviewed Original ResearchConceptsChronic diseasesReproductive-aged womenCommon chronic diseasesPathophysiology of endometriosisDisease-specific pathophysiologyRole of tissuePelvic painEndometriosis treatmentEndometriosisCandidate biomarkersPotential biomarkersNoninvasive toolSmall noncoding RNA moleculesDiseaseBiomarkersMultiple studiesPrecision medicineKey post-transcriptional regulatorsPathophysiologyNoncoding RNA moleculesMiRNA biomarkersDiagnosisMiRNA expressionFunctional pathwaysSpecific miRNAs
2018
Progesterone Receptor Status Predicts Response to Progestin Therapy in Endometriosis
Flores VA, Vanhie A, Dang T, Taylor HS. Progesterone Receptor Status Predicts Response to Progestin Therapy in Endometriosis. The Journal Of Clinical Endocrinology & Metabolism 2018, 103: 4561-4568. PMID: 30357380, PMCID: PMC6226602, DOI: 10.1210/jc.2018-01227.Peer-Reviewed Original ResearchConceptsProgestin-based therapyPR statusReceptor statusEndometriotic lesionsPredictive valueEndometriosis-associated painProgesterone receptor levelsRetrospective cohort studyFirst-line treatmentProgesterone receptor statusNegative predictive valuePositive predictive valueElectronic medical recordsRabbit polyclonal IgGPrecision-based approachesProgestin therapyHormonal therapyEndometriosis treatmentCohort studyPredictive markerMedical recordsReceptor levelsH-scoreAcademic centersEndometriosis
2017
Medical Therapies for Endometriosis Differentially Inhibit Stem Cell Recruitment
Sahin Ersoy GS, Zolbin MM, Cosar E, Mamillapalli R, Taylor HS. Medical Therapies for Endometriosis Differentially Inhibit Stem Cell Recruitment. Reproductive Sciences 2017, 24: 818-823. PMID: 28256937, DOI: 10.1177/1933719116682879.Peer-Reviewed Original ResearchConceptsBone marrow-derived stem cellsMedroxyprogesterone acetateEstrogen deprivationEndometriosis lesionsStem cell recruitmentCell recruitmentLesions of endometriosisGreen fluorescent protein miceWeeks of treatmentBone marrow transplantLong-term treatmentMarrow-derived stem cellsStem cellsProgestin medroxyprogesterone acetateLong-term regressionBone marrow stem cellsStem cell engraftmentMarrow stem cellsProgestin therapyEndometriosis treatmentLesion regressionMedical therapyEndometriotic lesionsMarrow transplantC57BL/6 mice
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