2024
Toxicity and Efficacy of Isavuconazole Vs Voriconazole As Anti-Fungal Prophylaxis for Patients with Acute Myeloid Leukemia
Hunter C, Bewersdorf J, Mendez L, Podoltsev N, Zeidan A, Eighmy W, Roeder H, Malinis M, Shallis R. Toxicity and Efficacy of Isavuconazole Vs Voriconazole As Anti-Fungal Prophylaxis for Patients with Acute Myeloid Leukemia. Blood 2024, 144: 1480-1480. DOI: 10.1182/blood-2024-211250.Peer-Reviewed Original ResearchInvasive fungal infectionsAcute myeloid leukemiaAntifungal prophylaxisDiagnosed AMLDrug-drug interactionsTransaminase elevationVisual disturbancesRates of invasive fungal infectionsInvasive fungal infections incidenceBaseline ANCCD4 countMyeloid leukemiaAllogeneic stem cell transplantationAnti-fungal prophylaxisAcute myeloid leukemia diagnosisDuration of neutropeniaBaseline CD4 countLess-intensive therapyStem cell transplantationPatient baseline characteristicsSide effect profileCandida sppTriazole agentsWilcoxon rank sum testAntifungal voriconazole
2023
Heidenhain variant of Creutzfeldt-Jakob disease masquerading as neuromyelitis optica spectrum disorder: recognizing when apheresis is not the answer
Burke O, Jacobs J, Tormey C, Rinder H, Villalba C, Lee E, Campos J, Abels E, Yurtsever N. Heidenhain variant of Creutzfeldt-Jakob disease masquerading as neuromyelitis optica spectrum disorder: recognizing when apheresis is not the answer. Lab Medicine 2023, 55: 520-523. PMID: 38142129, DOI: 10.1093/labmed/lmad107.Peer-Reviewed Original ResearchNeuromyelitis optica spectrum disorderCreutzfeld-Jakob diseaseOptica spectrum disorderHeidenhain variantBilateral vision lossTherapeutic plasma exchangeReal-time quaking-induced conversionCreutzfeldt-Jakob diseaseImmunosuppressive therapyVisual disturbancesPlasma exchangeNeurocognitive symptomsTreatment modalitiesVision lossHospice careSpectrum disorderRare formPreliminary diagnosisDiseaseDiagnosisDisordersEarly stagesPatientsApheresisTherapy
2021
Resection of Symptomatic Pineal Cysts Provides Durable Clinical Improvement: A Breakdown of Presenting Symptoms and Lessons Learned
Yeung JT, Young IM, Profyris C, Katsos K, Sughrue ME, Teo C. Resection of Symptomatic Pineal Cysts Provides Durable Clinical Improvement: A Breakdown of Presenting Symptoms and Lessons Learned. World Neurosurgery 2021, 150: e668-e674. PMID: 33771749, DOI: 10.1016/j.wneu.2021.03.087.Peer-Reviewed Original ResearchConceptsSymptomatic pineal cystsPineal cystsSurgical resectionClinical improvementDurable clinical improvementExhaustive conservative managementNon-headache symptomsDurable symptomatic reliefYears of agePresenting symptomConservative managementSymptomatic patientsSurgical candidacySymptomatic reliefVisual disturbancesClinical outcomesPatient populationRadiographic changesCerebral aqueductRetrospective analysisResectionPatientsVariable symptomsCystsHeadache
2019
Loss of UGP2 in brain leads to a severe epileptic encephalopathy, emphasizing that bi-allelic isoform-specific start-loss mutations of essential genes can cause genetic diseases
Perenthaler E, Nikoncuk A, Yousefi S, Berdowski WM, Alsagob M, Capo I, van der Linde HC, van den Berg P, Jacobs EH, Putar D, Ghazvini M, Aronica E, van IJcken WFJ, de Valk WG, Medici-van den Herik E, van Slegtenhorst M, Brick L, Kozenko M, Kohler JN, Bernstein JA, Monaghan KG, Begtrup A, Torene R, Al Futaisi A, Al Murshedi F, Mani R, Al Azri F, Kamsteeg EJ, Mojarrad M, Eslahi A, Khazaei Z, Darmiyan FM, Doosti M, Karimiani EG, Vandrovcova J, Zafar F, Rana N, Kandaswamy KK, Hertecant J, Bauer P, AlMuhaizea MA, Salih MA, Aldosary M, Almass R, Al-Quait L, Qubbaj W, Coskun S, Alahmadi KO, Hamad MHA, Alwadaee S, Awartani K, Dababo AM, Almohanna F, Colak D, Dehghani M, Mehrjardi MYV, Gunel M, Ercan-Sencicek AG, Passi GR, Cheema HA, Efthymiou S, Houlden H, Bertoli-Avella AM, Brooks AS, Retterer K, Maroofian R, Kaya N, van Ham TJ, Barakat TS. Loss of UGP2 in brain leads to a severe epileptic encephalopathy, emphasizing that bi-allelic isoform-specific start-loss mutations of essential genes can cause genetic diseases. Acta Neuropathologica 2019, 139: 415-442. PMID: 31820119, PMCID: PMC7035241, DOI: 10.1007/s00401-019-02109-6.Peer-Reviewed Original ResearchConceptsUDP-glucose pyrophosphorylase genePluripotent stem cell differentiationGenetic diseasesUnfolded protein responseVisual disturbancesAltered glycogen metabolismPremature neuronal differentiationStem cell differentiationEpileptic encephalopathyUpregulated unfolded protein responseDevelopmental delayEssential genesEssential proteinsTherapy-resistant seizuresDifferentiation defectsMutant animalsStart codonMultiple lineagesProtein responseNeural stem cellsSevere epileptic encephalopathySimilar disease mechanismsSevere developmental delayShort isoformProtein absenceOn Neuropsychiatric Manifestations of Basal Ganglia Injury: A Report of Three Cases and Literature Review
Azizi H, Kilpatrick A, Olayinka O, Poopola O, Ahmad M, Kahn A, Khan T, Rimawi D, Williams S, Jayaraj S, Leung I, Langdon S, Iskander M, Chohan A, Nuthalapati D, Umesi U, Vyas G, Oyelakin A, Kodjo K, Ojimba C, Jegede O, Nisenoff C, Jolayemi A. On Neuropsychiatric Manifestations of Basal Ganglia Injury: A Report of Three Cases and Literature Review. Case Reports In Neurological Medicine 2019, 2019: 3298791. PMID: 31080680, PMCID: PMC6475530, DOI: 10.1155/2019/3298791.Peer-Reviewed Original ResearchBasal ganglia pathologyNeuropsychiatric manifestationsBasal gangliaBilateral basal ganglia calcificationBasal ganglia injuryTreatment-refractory psychosisBasal ganglia calcificationDiagnosis of schizophreniaRefractory psychosisVisual disturbancesClinical evidenceMotor functionPsychiatric symptomsNeurological etiologyPsychotic symptomsSymptomsAffective disturbancesSubsequent manifestationPsychotic disturbancesPathologyMotor processingPatientsGangliaManifestationsThird case
2018
Superior Pituitary Border Analysis in Immunotherapy-Induced Hypophysitis
Pucar D, Boustani AM, Bronen RA, Saperstein L. Superior Pituitary Border Analysis in Immunotherapy-Induced Hypophysitis. Clinical Nuclear Medicine 2018, 43: 284-286. PMID: 29401149, DOI: 10.1097/rlu.0000000000001981.Peer-Reviewed Educational MaterialsConceptsSinus diseasePituitary swellingSevere headacheVisual disturbancesLaboratory findingsMetastatic melanomaPituitary abnormalitiesRetrospective analysisContrast CTNoncontrast CTPituitary hormonesHypophysitisHeadacheDiseaseDiagnosisCTLow levelsNivolumabHypermetabolismImmunotherapyPETMelanomaAbnormalitiesFindingsHormone
2017
Limitations of the endonasal endoscopic approach in treating olfactory groove meningiomas. A systematic review
Shetty SR, Ruiz-Treviño AS, Omay SB, Almeida JP, Liang B, Chen YN, Singh H, Schwartz TH. Limitations of the endonasal endoscopic approach in treating olfactory groove meningiomas. A systematic review. Acta Neurochirurgica 2017, 159: 1875-1885. PMID: 28831590, DOI: 10.1007/s00701-017-3303-0.Peer-Reviewed Original ResearchConceptsExtent of resectionOlfactory groove meningiomasTCA groupEndoscopic endonasalEEA patientsEEA groupTraditional transcranialPreoperative visual disturbancesMedium-sized tumorsFischer's exact testEndonasal endoscopic approachT-testStudent's t-testCurrent management strategiesPostoperative anosmiaPreoperative anosmiaTCA patientsPostoperative complicationsVisual outcomeEndoscopic resectionVisual disturbancesRecurrence rateSkull base reconstructionEndoscopic approachCSF leak
2016
The Effect of Preoperative Pregabalin on Postoperative Nausea and Vomiting
Grant M, Betz M, Hulse M, Zorrilla-Vaca A, Hobson D, Wick E, Wu C. The Effect of Preoperative Pregabalin on Postoperative Nausea and Vomiting. Anesthesia & Analgesia 2016, 123: 1100-1107. PMID: 27464972, DOI: 10.1213/ane.0000000000001404.Peer-Reviewed Original ResearchConceptsPreoperative pregabalinPostoperative nauseaPostoperative visual disturbancesPrevention of PONVSimilar antiemetic efficacyHigh-risk surgerySignificant reductionAdjuvant medicationsAntiemetic efficacyProphylactic antiemeticsThiopental inductionOpioid analgesiaPostoperative painSurgery protocolVisual disturbancesRandomized trialsRepeat dosingGeneral anesthesiaSubgroup analysisPregabalinEnhanced recoveryPONVNauseaVomitingTrialsDisease prevalence in a rural Andean population of central Peru: a focus on autoimmune and allergic diseases
Caturegli G, Caturegli P. Disease prevalence in a rural Andean population of central Peru: a focus on autoimmune and allergic diseases. Autoimmunity Highlights 2016, 7: 3. PMID: 26861900, PMCID: PMC4749512, DOI: 10.1007/s13317-016-0076-z.Peer-Reviewed Original ResearchAutoimmune diseasesConsecutive clinic daysHygiene hypothesisDisease prevalenceDouble-blind fashionOne-page formPublic health interventionsHealth interventionsBack painClinic daysPhysician notesHashimoto's thyroiditisVision lossVisual disturbancesClinical groundsPrescribed medicationsIncreased incidenceDe-identifiedImaging testsMedical missionsAllergic diseasesRheumatoid arthritisStomach painAmerican physiciansPatients
2014
Brain metastasis from ovarian cancer: a systematic review
Pakneshan S, Safarpour D, Tavassoli F, Jabbari B. Brain metastasis from ovarian cancer: a systematic review. Journal Of Neuro-Oncology 2014, 119: 1-6. PMID: 24789253, DOI: 10.1007/s11060-014-1447-9.Peer-Reviewed Original ResearchConceptsBrain metastasesOvarian cancerMultimodality treatmentRare causeBrain metastasis diagnosisHigher KPS scoreProgressive neurologic disabilityMajority of patientsMultiple brain lesionsSystematic literature searchOvarian cancer diagnosisLower KPSParaclinical informationKPS scoreExtracranial metastasesMedian survivalNeurologic disabilityOlder patientsSurgical resectionFavorable prognosisLymph nodesMedian ageMedical therapyVisual disturbancesCommon symptoms
2011
Ocular Neoplastic Disease
Mahajan A, Crum A, Johnson MH, Materin MA. Ocular Neoplastic Disease. Seminars In Ultrasound CT And MRI 2011, 32: 28-37. PMID: 21277489, DOI: 10.1053/j.sult.2010.12.001.Peer-Reviewed Original ResearchConceptsClinical ophthalmologic examinationOphthalmologic examinationScan ultrasoundCommon imaging appearancesMagnetic resonance imagingOcular metastasisOcular oncologistRetinal detachmentVisual disturbancesFluorescein angiographyMalignant neoplasmsMass lesionImaging appearancesTumor stagingVision lossDiagnostic findingsOcular neoplasmsUveal melanomaNeoplastic diseaseResonance imagingTreatment assessmentNeoplasmsStagingUltrasoundExamination
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply