2025
Association between prostate radiation therapy and survival among patients with metastatic prostate cancer by extent of disease burden.
Palencia P, Zhao X, Kandala K, Smani S, Sivanesan N, Cavallo J, Leapman M. Association between prostate radiation therapy and survival among patients with metastatic prostate cancer by extent of disease burden. Journal Of Clinical Oncology 2025, 43 DOI: 10.1200/jco.2025.43.16_suppl.e17123.Peer-Reviewed Original ResearchMetastatic hormone-sensitive prostate cancerAndrogen deprivation therapyProstate radiation therapyMetastatic prostate cancerOverall survivalRadiation therapyProstate cancerM1c diseaseTreatment modalitiesRT to ADTTreated with androgen deprivation therapyAssociated with improved overall survivalHormone-sensitive prostate cancerAssociated with poor overall survivalPrimary local therapyExternal beam radiotherapyGleason grade groupCompare overall survivalNational Cancer DatabaseProstate cancer metastasisLog-rank testDisease burdenKaplan-Meier curvesCox proportional hazards modelsLow disease burdenPsychosocial burden of axial spondyloarthritis and impact of different disease domains: a systematic literature review
Poddubnyy D, Kiltz U, Danve A, Wright G, Haberman R, Biljan A, Clewell J, Urbanik J, Jones H, Magrey M. Psychosocial burden of axial spondyloarthritis and impact of different disease domains: a systematic literature review. Rheumatology Advances In Practice 2025, 9: rkaf063. PMID: 40584930, PMCID: PMC12202762, DOI: 10.1093/rap/rkaf063.Peer-Reviewed Original ResearchRandomized Controlled TrialsPsychosocial outcomesDisease burdenHolistic treatment of patientsDisease domainsAxial spondyloarthritisPoor psychosocial outcomesDomains of disease activityOverall disease burdenPhysical functionPsychosocial burdenPsychosocial impactSystematic literature reviewHolistic treatmentLiterature searchAxSpAPsychosocial impairmentMorning stiffnessOverall functionOutcomesBidirectional relationshipLiterature reviewBurdenTNF inhibitor treatmentOptimal treatment responseA framework for managing infectious diseases in rural areas in low- and middle-income countries in the face of climate change—East Africa as a case study
Worsley-Tonks K, Angwenyi S, Carlson C, Cissé G, Deem S, Ferguson A, Fèvre E, Kimaro E, Kimiti D, Martins D, Merbold L, Mottet A, Murray S, Muturi M, Potter T, Prasad S, Wild H, Hassell J. A framework for managing infectious diseases in rural areas in low- and middle-income countries in the face of climate change—East Africa as a case study. PLOS Global Public Health 2025, 5: e0003892. PMID: 39883787, PMCID: PMC11781624, DOI: 10.1371/journal.pgph.0003892.Peer-Reviewed Original ResearchMiddle-income countriesHealth systemDisease riskClimate changeRural areasExposure to climate-related hazardsInfectious disease riskClimate change adaptation strategiesBurden of infectious diseasesChange adaptation strategiesClimate change impactsContext of climate changeClimate-related hazardsDisease burdenHealthRural communitiesChange impactsHuman healthSystems climateAdaptation strategiesClimateInfectious diseasesBurdenDisease scenariosRiskThe Complex Landscape of Updated Pneumococcal Conjugate Vaccines
Thindwa D, Shapiro E, Weinberger D. The Complex Landscape of Updated Pneumococcal Conjugate Vaccines. Open Forum Infectious Diseases 2025, 12: ofaf050. PMID: 39968305, PMCID: PMC11834978, DOI: 10.1093/ofid/ofaf050.Peer-Reviewed Original ResearchA Methodological Approach to Measuring the Impact of TAK-003 for the Prevention of Dengue in Dourados, Brazil: Optimizing Strategies for Public Health
Ghezzi B, Valencia C, de Oliveira R, Tsuha D, Júnior W, Di Pasquale A, Mc Namara M, Senra J, Abud D, Croda J. A Methodological Approach to Measuring the Impact of TAK-003 for the Prevention of Dengue in Dourados, Brazil: Optimizing Strategies for Public Health. Vaccines 2025, 13: 121. PMID: 40006668, PMCID: PMC11860522, DOI: 10.3390/vaccines13020121.Peer-Reviewed Original ResearchPopulation-based studyMunicipal Health SecretaryPublic health relevancePublic health problemPublic health importanceIndividuals aged 4Programmatic areasActive vaccination campaignsIncrease vaccine acceptanceHealth SecretaryProgram implementationDisease preventionHealthcare infrastructureHealth problemsDisease burdenHealth relevancePrevention of dengueVaccination program implementationFeasibility criteriaPublic healthPrincipal investigatorHealth importanceNational surveillanceAged 4Vaccination data
2024
Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analysis for the Global Burden of Disease Study 2021
Collaborators G, Kyu H, Vongpradith A, Dominguez R, Ma J, Albertson S, Novotney A, Khalil I, Troeger C, Doxey M, Ledesma J, Sirota S, Bender R, Swetschinski L, Cunningham M, Spearman S, Abate Y, Al Magied A, ElHafeez S, Abdoun M, Abera B, Abidi H, Aboagye R, Abtew Y, Abualruz H, Abu-Gharbieh E, Abukhadijah H, Aburuz S, Addo I, Adekanmbi V, Adetunji C, Adeyeoluwa T, Adhikary R, Adnani Q, Adra S, Adzigbli L, Afolabi A, Afzal M, Afzal S, Agampodi S, Agide F, Ahinkorah B, Ahmad A, Ahmad S, Ahmed A, Ahmed A, Ahmed H, Ahmed S, Akinosoglou K, Akter E, Al Awaidy S, Alajlani M, Alam K, Albakri A, Albashtawy M, Aldhaleei W, Algammal A, Al-Gheethi A, Ali A, Ali S, Ali W, Alif M, Aljunid S, Al-Marwani S, Almazan J, Al-Mekhlafi H, Almustanyir S, Alqahatni S, Alrawashdeh A, Al-Rifai R, Alsabri M, Altaf A, Altirkawi K, Alvis-Guzman N, Alvis-Zakzuk N, Alyahya M, Al-Zyoud W, Amugsi D, Andrei C, Antoni S, Anuoluwa B, Anuoluwa I, Anwar S, Anwari P, Apostol G, Arabloo J, Arafat M, Aravkin A, Areda D, Aregawi B, Aremu A, Arndt M, Asgedom A, Ashraf T, Athari S, Atreya A, Ayele F, Azadi D, Azhar G, Aziz S, Azzam A, Babu G, Taghanaki P, Bahramian S, Balakrishnan S, Banik B, Bante S, Bardhan M, Bärnighausen T, Barqawi H, Barrow A, Basharat Z, Bassat Q, Bastan M, Basu S, Bathini P, Behzadi P, Beiranvand M, Bello M, Bello O, Beloukas A, Beran A, Bhandari D, Bhardwaj P, Bhutta Z, Borhany H, Bouaoud S, Brauer M, Buonsenso D, Butt Z, Barsbay M, Cámera L, Capodici A, Castañeda-Orjuela C, Cenderadewi M, Chakraborty C, Chakraborty S, Chattu V, Chaudhary A, Chichagi F, Ching P, Chirinos-Caceres J, Chopra H, Choudhari S, Chowdhury E, Chu D, Chukwu I, Chutiyami M, Cruz-Martins N, Dadras O, Dai X, Dandona L, Dandona R, Darcho S, Das J, Dash N, Delgado-Enciso I, Desye B, Devanbu V, Dhama K, Dhimal M, Diaz M, Chi T, Dohare S, Dorostkar F, Doshi O, Doshmangir L, Dsouza H, Duraisamy S, Durojaiye O, E'mar A, Ed-Dra A, Edinur H, Efendi D, Efendi F, Eghbali F, Ekundayo T, Sayed I, Elhadi M, El-Metwally A, Elshaer M, Elsohaby I, Eltaha C, Eshrati B, Eslami M, Fahim A, Fakhradiyev I, Fakhri-Demeshghieh A, Farahmand M, Fasina F, Fasina M, Feizkhah A, Fekadu G, Ferreira N, Fetensa G, Fischer F, Fukumoto T, Fux B, Gadanya M, Gaihre S, Gajdács M, Galali Y, Gandhi A, Gautam R, Gebregergis M, Gebrehiwot M, Gebremeskel T, Getachew M, Getahun G, Getie M, Ghasemzadeh A, Ghazy R, Ghozy S, Gil A, Girmay A, Gizaw A, Golechha M, Goleij P, Gona P, Grada A, Guarducci G, Gudeta M, Gupta V, Habteyohannes A, Hadi N, Hamidi S, Hamilton E, Harapan H, Hasan K, Hasan S, Hasani H, Hasnain S, Hassan I, He J, Hemmati M, Hezam K, Hosseinzadeh M, Huang J, Huynh H, Ibitoye S, Ikuta K, Ilesanmi O, Ilic I, Ilic M, Inamdar S, Isa M, Islam R, Islam M, Ismail N, Iwu C, Jacobsen K, Jahrami H, Jain A, Jain N, Jairoun A, Jakovljevic M, Yengejeh R, Javidnia J, Jayaram S, Jokar M, Jonas J, Joseph A, Joseph N, Jozwiak J, Kabir H, Kadir D, Kamal M, Kamal V, Kamireddy A, Kanchan T, Kanmodi K, S S, Kantar R, Karami J, Karki P, Kasraei H, Kaur H, Keykhaei M, Khader Y, Khalilian A, Khamesipour F, Khan G, Khan M, Khan Z, Khanal V, Khatab K, Khatatbeh M, Khater A, Kheirallah K, Khidri F, Khosla A, Kim K, Kim Y, Kisa A, Kissoon N, Klu D, Kochhar S, Kolahi A, Kompani F, Kosen S, Krishan K, Defo B, Kuddus A, Kuddus M, Kulimbet M, Kumar G, Kumar R, Kyei-Arthur F, Lahariya C, Lal D, Le N, Lee S, Lee W, Lee Y, Li M, Ligade V, Liu G, Liu S, Liu X, Liu X, Lo C, Lucchetti G, Lv L, Malhotra K, Malik A, Marasini B, Martorell M, Marzo R, Masoumi-Asl H, Mathur M, Mathur N, Mediratta R, Meftah E, Meto T, Meles H, Melese E, Mendoza W, Merati M, Meretoja T, Mestrovic T, Mettananda S, Minh L, Mishra V, Mithra P, Mohamadkhani A, Mohamed A, Mohamed M, Mohamed N, Mohammed M, Mohammed S, Monasta L, Moni M, Motappa R, Mougin V, Mubarik S, Mulita F, Munjal K, Munkhsaikhan Y, Naghavi P, Naik G, Nair T, Najmuldeen H, Nargus S, Davani D, Nashwan A, Natto Z, Nazri-Panjaki A, Nchanji G, Ndishimye P, Ngunjiri J, Nguyen D, Nguyen N, Nguyen V, Nigatu Y, Nikoobar A, Niranjan V, Nnaji C, Noman E, Noor N, Noor S, Nouri M, Nozari M, Nri-Ezedi C, Nugen F, Odetokun I, Ogunfowokan A, Ojo-Akosile T, Okeke I, Okekunle A, Olorukooba A, Olufadewa I, Oluwatunase G, Orish V, Ortega-Altamirano D, Ortiz-Prado E, Osuagwu U, Osuolale O, Ouyahia A, Padubidri J, Pandey A, Pandey A, Pando-Robles V, Pardhan S, Parikh R, Patel J, Patil S, Pawar S, Peprah, Perianayagam A, Perna S, Petcu I, Philip A, Polibin R, Postma M, Pourtaheri N, Pradhan J, Prates E, Pribadi D, Qasim N, Qazi A, Deepthi R, Radhakrishnan V, Rahim F, Rahman M, Rahman M, Rahmani S, Rahmanian M, Rahmanian N, Ramadan M, Ramasamy S, Ramazanu S, Rameto M, Ramteke P, Rana K, Ranabhat C, Rasella D, Rashidi M, Rasouli-Saravani A, Rathish D, Rauniyar S, Rawaf S, Redwan E, Regmi A, Rengasamy K, Rezaei N, Rezaei N, Rezaeian M, Riad A, Rodrigues M, Rodriguez J, Roever L, Rohilla R, Ronfani L, Rony M, Ross A, Roudashti S, Roy B, Runghien T, Dhingra M, Saddik B, Sadeghi E, Safari M, Sahoo S, Sajadi S, Salami A, Saleh M, Kafil H, Samodra Y, Sanabria J, Sanjeev R, Sarkar T, Sartorius B, Sathian B, Satpathy M, Sawhney M, Schumacher A, Sebsibe M, Serban D, Shafie M, Shahid S, Shahid W, Shaikh M, Sham S, Shamim M, Shams-Beyranvand M, Shamshirgaran M, Shanawaz M, Shannawaz M, Sharifan A, Sharma M, Sharma V, Shenoy S, Sherchan S, Shetty M, Shetty P, Shiferaw D, Shittu A, Shorofi S, Siddig E, Silva L, Singh B, Singh J, Sinto R, Socea B, Soeters H, Sokhan A, Sood P, Soraneh S, Sreeramareddy C, Srinivasamurthy S, Srivastava V, Stanikzai M, Subedi N, Subramaniyan V, Sulaiman S, Suleman M, Swain C, Szarpak L, Y S, Tabatabaei S, Tabche C, Taha Z, Talukder A, Tamuzi J, Tan K, Tandukar S, Temsah M, Thakali O, Thakur R, Thirunavukkarasu S, Thomas J, Thomas N, Ticoalu J, Tiwari K, Tovani-Palone M, Tram K, Tran A, Tran N, Tran T, Tromans S, Truyen T, Tumurkhuu M, Udoakang A, Udoh A, Ullah S, Umair M, Umar M, Unim B, Unnikrishnan B, Vahdati S, Vaithinathan A, Valizadeh R, Verma M, Verras G, Vinayak M, Waheed Y, Walde M, Wang Y, Waqas M, Weerakoon K, Wickramasinghe N, Wolde A, Wu F, Yaghoubi S, Yaya S, Yezli S, Yiğit V, Yin D, Yon D, Yonemoto N, Yusuf H, Zahid M, Zakham F, Zaki L, Zare I, Zastrozhin M, Zeariya M, Zhang H, Zhang Z, Zhumagaliuly A, Zia H, Zoladl M, Mokdad A, Lim S, Vos T, Platts-Mills J, Mosser J, Reiner R, Hay S, Naghavi M, Murray C. Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet Infectious Diseases 2024, 25: 519-536. PMID: 39708822, PMCID: PMC12018300, DOI: 10.1016/s1473-3099(24)00691-1.Peer-Reviewed Original ResearchPopulation-attributable fractionDiarrhoeal disease burdenGlobal burdenBurden of diarrhoeal diseaseRisk factorsEffectiveness of health interventionsGlobal Burden of Disease StudyBayesian meta-regression toolBurden of Disease StudyGlobal Burden of DiseaseComparative risk assessment frameworkDisease burdenDisability-adjusted life yearsPopulation-based surveyVerbal autopsy dataRisk Factors StudyMortality surveillance dataVital registration dataChild growth failureIndependent effects of risk factorsEffects of risk factorsAge groupsBurden of diseaseAge-sex groupsYears of lifeEstimating the health and macroeconomic burdens of tuberculosis in India, 2021–2040: A fully integrated modelling study
Keogh-Brown M, Sumner T, Sweeney S, Vassall A, Jensen H. Estimating the health and macroeconomic burdens of tuberculosis in India, 2021–2040: A fully integrated modelling study. PLOS Medicine 2024, 21: e1004491. PMID: 39666614, PMCID: PMC11637336, DOI: 10.1371/journal.pmed.1004491.Peer-Reviewed Original ResearchConceptsGross domestic productMacroeconomic burdenCumulative gross domestic productReturn to investmentHigh-income householdsLow-income householdsDomestic productEconomic growthReduction targetsIndian economyEconomic gainsInvestmentEconomic impactEconomyCountriesHouseholdsBurden of TBEconomic burdenDisease burdenFundingImpact of TBLarge healthCase detectionTB-related deathsProvisionThe Association Between Patient-Reported Disease Burden and Treatment Switching in Patients with Plaque Psoriasis Treated with Nonbiologic Systemic Therapy
Patel V, Park S, Zhong Y, Sima A, Zhuo J, Roberts-Toler C, Becker B, Hovland S, Strober B. The Association Between Patient-Reported Disease Burden and Treatment Switching in Patients with Plaque Psoriasis Treated with Nonbiologic Systemic Therapy. Psoriasis Targets And Therapy 2024, 14: 167-174. PMID: 39624651, PMCID: PMC11610380, DOI: 10.2147/ptt.s478352.Peer-Reviewed Original ResearchPatient-reported disease burdenVisual analog scaleBiologic therapyPlaque psoriasisDisease burdenOdds ratioInitiation of biologic therapyQuality of lifeCorEvitas Psoriasis RegistryNonbiologic systemic therapyDisease severityPatient-reported burdenMultivariate logistic regression modelDermatology Life Quality IndexDays of enrollmentReal-world studyWork Productivity and Activity Impairment QuestionnaireLife Quality IndexPhysician-rated disease severityTherapy-naiveBiologic-naiveHealth-related quality of lifePsoriasis RegistrySystemic therapySkin painA rare case of disseminated amebiasis in a patient on biologic therapy for chronic rhinosinusitis
Omiunu A, Brown L, Kayastha D, Manes R. A rare case of disseminated amebiasis in a patient on biologic therapy for chronic rhinosinusitis. International Forum Of Allergy & Rhinology 2024, 15: 86-88. PMID: 39444259, DOI: 10.1002/alr.23473.Peer-Reviewed Original ResearchComplete vs. Incomplete Consolidative Radiotherapy in Patients with Extensive-Stage Small Cell Lung Cancer
Ninia J, Verma N, Laird J, Hayman T, Knowlton C, Peters G, Campbell A, Housri N, Feghali K, de Jong D, Park H. Complete vs. Incomplete Consolidative Radiotherapy in Patients with Extensive-Stage Small Cell Lung Cancer. International Journal Of Radiation Oncology • Biology • Physics 2024, 120: e51. DOI: 10.1016/j.ijrobp.2024.07.1890.Peer-Reviewed Original ResearchExtensive-stage small cell lung cancerProgression-free survivalSmall cell lung cancerOverall survivalCell lung cancerOligometastatic diseaseChemo-ImmunotherapyLung cancerSuperior progression-free survivalMedian follow-up timePatients treated with CCSites of disease involvementConsolidative thoracic radiotherapyAssociated with improved outcomesChemotherapy-based treatmentStratified Cox proportional hazard regressionsLog-rank testCox proportional hazards regressionDisease burdenTime of diagnosisKaplan-Meier estimatesProportional hazards regressionConsolidation radiotherapyPolymetastatic diseaseOligometastatic patientsW94. ALLELE FREQUENCIES AT CRUCIAL LOCI MIGHT UNDERLIE DISPARATE CONSEQUENCES OF ALCOHOL ABUSE ACROSS WORLD POPULATIONS
Shankarappa B, Ganesh S, Purushottam M, Jain S. W94. ALLELE FREQUENCIES AT CRUCIAL LOCI MIGHT UNDERLIE DISPARATE CONSEQUENCES OF ALCOHOL ABUSE ACROSS WORLD POPULATIONS. European Neuropsychopharmacology 2024, 87: 151. DOI: 10.1016/j.euroneuro.2024.08.303.Peer-Reviewed Original ResearchDistribution of allele frequenciesAllele frequenciesAlcohol use disorderAlcohol-related comorbiditiesAlcohol abuseUse disorderHeritability of alcohol use disordersRisk of diseaseIll healthSequence alignmentSIFT scoreAlcohol consumptionAlcohol-related complicationsHealth consequencesAlcohol useAssociated with alcoholDisease burdenConsequences of alcohol abuseHealth complicationsContext of alcohol abuseRisk factorsHealthGenetic predispositionMetabolize alcoholCultural practicesIncorporating Social Determinants of Health in Infectious Disease Models: A Systematic Review of Guidelines
Ali S, Li Z, Moqueet N, Moghadas S, Galvani A, Cooper L, Stranges S, Haworth-Brockman M, Pinto A, Asaria M, Champredon D, Hamilton D, Moulin M, John-Baptiste A. Incorporating Social Determinants of Health in Infectious Disease Models: A Systematic Review of Guidelines. Medical Decision Making 2024, 44: 742-755. PMID: 39305116, PMCID: PMC11491037, DOI: 10.1177/0272989x241280611.Peer-Reviewed Original ResearchSocial determinants of healthDeterminants of healthIncorporating social determinants of healthSocial determinantsSystematic review of guidelinesDisease riskHealth burdenPolicy impactImprove equitable accessSocial groupsImplementation challengesReview of guidelinesSocial heterogeneityImpact of infectious disease outbreaksSocioeconomic statusMitigation of disparitiesSystematic reviewEquitable accessDisease burdenEstimate policy impactsHealthID guidelinesInfectious disease outbreaksCOVID-19 pandemicDistributional impactsBeta Spike-Presenting SARS-CoV-2 Virus-like Particle Vaccine Confers Broad Protection against Other VOCs in Mice
Ullah I, Symmes K, Keita K, Zhu L, Grunst M, Li W, Mothes W, Kumar P, Uchil P. Beta Spike-Presenting SARS-CoV-2 Virus-like Particle Vaccine Confers Broad Protection against Other VOCs in Mice. Vaccines 2024, 12: 1007. PMID: 39340037, PMCID: PMC11435481, DOI: 10.3390/vaccines12091007.Peer-Reviewed Original ResearchImmune responseVirus-like particlesBeta spikesCross-protective immune responsesSARS-CoV-2 immunitySARS-CoV-2Effective immune responseEffective humoral immune responseHumoral immune responseAncestral spikeT cellsVaccination regimenSARS-CoV-2 virus-like particlesVaccine platformMouse modelVariant spike proteinsOmicron spikeBeta variantDisease burdenNon-infectiousReduce virus spreadImmunityVariant spikesFusion glycoproteinSpike proteinProposed Mechanisms and Associations of COVID-19 with Cardiometabolic Risk Factors.
Reddy K, Faridi K, Aggarwal M, Tirumalai A, Singh T, Tejtel K, Williams K, Litwin S, Dastmalchi L, White B, Barnard N, Ornish D, Batts T, Ajene G, Aspry K, Kris Etherton P, Hull S, Freeman A. Proposed Mechanisms and Associations of COVID-19 with Cardiometabolic Risk Factors. American Journal Of Lifestyle Medicine 2024, 15598276241269532. PMID: 39540176, PMCID: PMC11556543, DOI: 10.1177/15598276241269532.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCardiometabolic riskLifestyle choicesCardiovascular diseaseHealthy lifestyle choicesCardiometabolic risk factorsHealth promotionReduce disease burdenCode BlueCardiovascular healthDisease preventionCOVID-19 morbidityPoor nutritionDisease burdenCOVID-19Disease burden resultsPublic healthGlobal leading causeLeading causeRisk factorsAssociation of COVID-19HealthLifestyleBurden resultsNutritionCardiovascular medicine‘Exerkines’: A Comprehensive Term for the Factors Produced in Response to Exercise
Novelli G, Calcaterra G, Casciani F, Pecorelli S, Mehta J. ‘Exerkines’: A Comprehensive Term for the Factors Produced in Response to Exercise. Biomedicines 2024, 12: 1975. PMID: 39335489, PMCID: PMC11429193, DOI: 10.3390/biomedicines12091975.Peer-Reviewed Original ResearchPhysical activityMuscle adaptationBenefits of physical trainingMultiple benefits of exerciseBenefits of exerciseEffects of exerciseRegular exerciseLifestyle factorsPhysical exercisePhysical trainingExerkinesExerciseDisease burdenHealthPrevent diseaseHealth implicationsHealth benefitsClinical course of diseaseCourse of diseaseTissue adaptationPharmacological therapyMuscleClinical courseAutocrine pathwayMetabolic regulationPatient Perspectives on Social and Identity Factors Affecting Multiple Myeloma Care: Barriers and Opportunities
Neparidze N, Godara A, Lin D, Le H, Fixler K, Shea L, Everson S, Brittle C, Brunisholz K. Patient Perspectives on Social and Identity Factors Affecting Multiple Myeloma Care: Barriers and Opportunities. Healthcare 2024, 12: 1587. PMID: 39201146, PMCID: PMC11354118, DOI: 10.3390/healthcare12161587.Peer-Reviewed Original ResearchDisease journeyHealth care providersImprove patient supportCare providersPatient prioritiesPatient advocatesPatient perspectiveMedical appointmentsMultiple myelomaPatient supportMultiple barriersInformed treatment decisionsPrioritized needsMultidisciplinary teamTreatment adherenceDisease burdenFocus group researchComprehensive supportImprove outcomesSocial workersTreatment decisionsInsurance optionsMixing methodBurdenSupportComparing suicide completion rates in bipolar I versus bipolar II disorder: A systematic review and meta-analysis
Dev D, Le G, Kwan A, Wong S, Arulmozhi A, Ceban F, Teopiz K, Meshkat S, Rosenblat J, Guillen-Burgos H, Rhee T, Ho R, Cao B, d'Andrea G, Sundberg I, McIntyre R. Comparing suicide completion rates in bipolar I versus bipolar II disorder: A systematic review and meta-analysis. Journal Of Affective Disorders 2024, 361: 480-488. PMID: 38901691, DOI: 10.1016/j.jad.2024.06.045.Peer-Reviewed Original ResearchSuicide completion ratesCompletion ratesMeta-analysisSystematic reviewRisk of completed suicideHeterogeneity of studiesCompared to personsPooled odds ratioHigher mortality riskRate of completed suicideBipolar disorderIllness burdenPsychINFO databasesBD-IBD-IIMortality riskMortality hazardEligibility criteriaPRISMA guidelinesDisease burdenSuicide ratesLiterature searchSuicideBipolar disorder type IINon-significantPrevalence and prognostic importance of exercise limitation and physical inactivity in COPD
Vaes A, Burtin C, Casaburi R, Celli B, Evans R, Lareau S, Nici L, Rochester C, Troosters T. Prevalence and prognostic importance of exercise limitation and physical inactivity in COPD. Breathe 2024, 20: 230179. PMID: 38873237, PMCID: PMC11167648, DOI: 10.1183/20734735.0179-2023.Peer-Reviewed Original ResearchPhysical inactivityExercise limitationWalk testExercise performanceEndurance shuttle walk testExercise capacityMeasures of exercise performanceShuttle walk testAssess exercise capacityAssociated with mortalityExerciseDisease burdenInactivityPredictive of adverse outcomesAdverse outcomesCOPDAdditional resourcesNegative outcomesOutcomesTreadmillRespiratory impairmentEnduranceCliniciansPrevalenceBurdenCorrelation of body mass index (BMI) with survival outcomes in patients (pts) with metastatic hormone-sensitive prostate cancer (mHSPC): Analysis of patient (pt)-level data from SWOG 1216 study.
Swami U, Jo Y, Narang A, Plets M, Hage Chehade C, Gebrael G, Gupta S, Myint Z, Tangen C, Lara P, Thompson I, Hussain M, Dorff T, Lerner S, Agarwal N. Correlation of body mass index (BMI) with survival outcomes in patients (pts) with metastatic hormone-sensitive prostate cancer (mHSPC): Analysis of patient (pt)-level data from SWOG 1216 study. Journal Of Clinical Oncology 2024, 42: 5081-5081. DOI: 10.1200/jco.2024.42.16_suppl.5081.Peer-Reviewed Original ResearchMetastatic hormone-sensitive prostate cancerBody mass indexBody mass index cohortZubrod performance statusCorrelation of body mass indexPhase III studyOverall survivalSurvival outcomesGleason scoreIII studiesPerformance statusProstate cancerMetastatic hormone-sensitive prostate cancer settingAssociated with improved survival outcomesMetastatic castration-resistant prostate cancerMultivariate analysisHormone-sensitive prostate cancerAssociated with better OSRandomized phase III studyCastration-resistant prostate cancerNormal body mass indexCategorized body mass indexPrognostication of patientsAssociation of obesityDisease burdenThe brain structure, inflammatory, and genetic mechanisms mediate the association between physical frailty and depression
Jiang R, Noble S, Rosenblatt M, Dai W, Ye J, Liu S, Qi S, Calhoun V, Sui J, Scheinost D. The brain structure, inflammatory, and genetic mechanisms mediate the association between physical frailty and depression. Nature Communications 2024, 15: 4411. PMID: 38782943, PMCID: PMC11116547, DOI: 10.1038/s41467-024-48827-8.Peer-Reviewed Original ResearchConceptsIncident depressionPre-frailPhysical frailtyFrail individualsPopulation attributable fraction analysisRisk factors of depressionMendelian randomization analysisFactors of depressionPotential causal effectModifiable risk factorsNon-frail individualsCross-sectional studyEffect of frailtyHigher disease burdenUK BiobankRandomization analysisBrain volumeDepression casesDisease burdenFrailtyRegional brain volumesIncreased riskDepressionHigh riskFollow-up
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