2022
MULTIMORBIDITY PROGRESSION AMONG MEDICARE BENEFICIARIES IN THE HEALTH AND RETIREMENT STUDY (1991–2015)
Quiñones A, Markwardt S, Bobo M, Allore H, Newsom J, Nagel C, Botoseneanu A, Dorr D. MULTIMORBIDITY PROGRESSION AMONG MEDICARE BENEFICIARIES IN THE HEALTH AND RETIREMENT STUDY (1991–2015). Innovation In Aging 2022, 6: 693-693. DOI: 10.1093/geroni/igac059.2540.Peer-Reviewed Original ResearchMultimorbidity groupObese body mass indexOlder adultsLevel of multimorbidityBody mass indexHigh incidence rateHigh multimorbidityMass indexIncidence rateED ratesMultimorbidityMedicare beneficiariesMedicare feeBirth cohortService beneficiariesLower multimorbidityFunctional lossGreater riskSociodemographic differencesDisease accumulationLater lifeAbstract Older adultsRetirement StudyHigher proportionAdults
2020
The Effect of Ethnicity in the Rate of Beta-Cell Functional Loss in the First 3 Years After Type 1 Diabetes Diagnosis
Tosur M, Cleves M, Sosenko J, Libman I, Baidal D, Balasubramanyam A, Redondo M, Greenbaum C, Anderson M, Antinozzi P, Atkinson M, Battaglia M, Becker D, Bingley P, Bosi E, Buckner J, Colman P, DiMeglio L, Gitelman S, Goland R, Gottlieb P, Herold K, Insel R, Kay T, Knip M, Krischer J, Lernmark A, Marks J, Moran A, Palmer J, Peakman M, Philipson L, Pugliese A, Raskin P, Redondo M, Rodriguez H, Roep B, Russell W, Spain L, Schatz D, Sosenko J, Wherrett D, Wilson D, Winter W, Ziegler A, Benoist C, Blum J, Bourcier K, Chase P, Clare-Salzler M, Clynes R, Eisenbarth G, Fathman C, Grave G, Hering B, Kaufman F, Leschek E, Mahon J, Nanto-Salonen K, Nepom G, Orban T, Parkman R, Pescovitz M, Peyman J, Roncarolo M, Savage P, Simell O, Sherwin R, Siegelman M, Skyler J, Steck A, Thomas J, Trucco M, Wagner J, Greenbaum C, Bourcier K, Insel R, Krischer J, Leschek E, Rafkin L, Spain L, Cowie C, Foulkes M, Krause-Steinrauf H, Lachin J, Malozowski S, Peyman J, Ridge J, Savage P, Skyler J, Zafonte S, Greenbaum C, Kenyon N, Rafkin L, Santiago I, Sosenko J, Skyler J, Krischer J, Bundy B, Abbondondolo M, Adams T, Amado D, Asif I, Boonstra M, Bundy B, Burroughs C, Cuthbertson D, Deemer M, Eberhard C, Fiske S, Ford J, Garmeson J, Guillette H, Geyer S, Hays B, Henderson C, Henry M, Heyman K, Hsiao B, Karges C, Keaton N, Kinderman A, Law P, Leinbach A, Linton C, Liu S, Lloyd J, Malloy J, Maddox K, Martin J, Miller J, Milliot E, Moore M, Muller S, Nguyen T, O’Donnell R, Oduah V, Pilger J, Roberts A, Sadler K, Stavros T, Tamura R, Wood K, Xu P, Young K, Alies P, Badias F, Baker A, Bassi M, Beam C, Boulware D, Bounmananh L, Bream S, Freeman D, Gough J, Ginem J, Granger M, Kieffer M, Lane P, Nallamshetty L, Parrimon Y, Paulus K, Ramiro J, Ritzie A, Sharma A, Shor A, Song X, Terry A, Weinberger J, Wootten M, Lachin J, Foulkes M, Harding P, Krause-Steinrauf H, McDonough S, McGee P, Hess K, Phoebus D, Quinlan S, Raiden E, Greenbaum C, Batts E, Buddy C, Kirpatrick K, Ramey M, Shultz A, Webb C, Romesco M, Fradkin J, Leschek E, Spain L, Savage P, Blumberg E, Beck G, Brillon D, Gubitosi-Klug R, Laffel L, Veatch R, Wallace D, Braun J, Lernmark A, Lo B, Mitchell H, Naji A, Nerup J, Orchard T, Steffes M, Tsiatis A, Zinman B, Loechelt B, Baden L, Green M, Weinberg A, Marcovina S, Palmer J, Weinberg A, Yu L, Babu S, Winter W, Eisenbarth G, Bingley P, Clynes R, DiMeglio L, Eisenbarth G, Greenbaum C, Hays B, Krischer J, Leschek E, Marks J, Matheson D, Rafkin L, Rodriguez H, Skyler J, Sosenko J, Spain L, Wilson D, Redondo M, Gomez D, Zheng X, Pena S, Pietropaolo M, Greenbaum C, Batts E, Brown T, Buckner J, Dove A, Hammond M, Hefty D, Klein J, Kuhns K, Letlau M, Lord S, McCulloch-Olson M, Miller L, Nepom G, Odegard J, Ramey M, Sachter E, St. Marie M, Stickney K, VanBuecken D, Vellek B, Webber C, Allen L, Bollyk J, Hilderman N, Ismail H, Lamola S, Sanda S, Vendettuoli H, Tridgell D, Monzavi R, Bock M, Fisher L, Halvorson M, Jeandron D, Kim M, Wood J, Geffner M, Kaufman F, Parkman R, Salazar C, Goland R, Clynes R, Cook S, Freeby M, Gallagher M, Gandica R, Greenberg E, Kurland A, Pollak S, Wolk A, Chan M, Koplimae L, Levine E, Smith K, Trast J, DiMeglio L, Blum J, Evans-Molina C, Hufferd R, Jagielo B, Kruse C, Patrick V, Rigby M, Spall M, Swinney K, Terrell J, Christner L, Ford L, Lynch S, Menendez M, Merrill P, Pescovitz M, Rodriguez H, Alleyn C, Baidal D, Fay S, Gaglia J, Resnick B, Szubowicz S, Weir G, Benjamin R, Conboy D, deManbey A, Jackson R, Jalahej H, Orban T, Ricker A, Wolfsdorf J, Zhang H, Wilson D, Aye T, Baker B, Barahona K, Buckingham B, Esrey K, Esrey T, Fathman G, Snyder R, Aneja B, Chatav M, Espinoza O, Frank E, Liu J, Perry J, Pyle R, Rigby A, Riley K, Soto A, Gitelman S, Adi S, Anderson M, Berhel A, Breen K, Fraser K, Gerard-Gonzalez A, Jossan P, Lustig R, Moassesfar S, Mugg A, Ng D, Prahalod P, Rangel-Lugo M, Sanda S, Tarkoff J, Torok C, Wesch R, Aslan I, Buchanan J, Cordier J, Hamilton C, Hawkins L, Ho T, Jain A, Ko K, Lee T, Phelps S, Rosenthal S, Sahakitrungruang T, Stehl L, Taylor L, Wertz M, Wong J, Philipson L, Briars R, Devine N, Littlejohn E, Grant T, Gottlieb P, Klingensmith G, Steck A, Alkanani A, Bautista K, Bedoy R, Blau A, Burke B, Cory L, Dang M, Fitzgerald-Miller L, Fouts A, Gage V, Garg S, Gesauldo P, Gutin R, Hayes C, Hoffman M, Ketchum K, Logsden-Sackett N, Maahs D, Messer L, Meyers L, Michels A, Peacock S, Rewers M, Rodriguez P, Sepulbeda F, Sippl R, Steck A, Taki I, Tran B, Tran T, Wadwa R, Zeitler P, Barker J, Barry S, Birks L, Bomsburger L, Bookert T, Briggs L, Burdick P, Cabrera R, Chase P, Cobry E, Conley A, Cook G, Daniels J, DiDomenico D, Eckert J, Ehler A, Eisenbarth G, Fain P, Fiallo-Scharer R, Frank N, Goettle H, Haarhues M, Harris S, Horton L, Hutton J, Jeffrrey J, Jenison R, Jones K, Kastelic W, King M, Lehr D, Lungaro J, Mason K, Maurer H, Nguyen L, Proto A, Realsen J, Schmitt K, Schwartz M, Skovgaard S, Smith J, Vanderwel B, Voelmle M, Wagner R, Wallace A, Walravens P, Weiner L, Westerhoff B, Westfall E, Widmer K, Wright H, Schatz D, Abraham A, Atkinson M, Cintron M, Clare-Salzler M, Ferguson J, Haller M, Hosford J, Mancini D, Rohrs H, Silverstein J, Thomas J, Winter W, Cole G, Cook R, Coy R, Hicks E, Lewis N, Marks J, Pugliese A, Blaschke C, Matheson D, Pugliese A, Sanders-Branca N, Sosenko J, Arce L, Cisneros M, Sabbag S, Moran A, Gibson C, Fife B, Hering B, Kwong C, Leschyshyn J, Nathan B, Pappenfus B, Street A, Boes M, Eck S, Finney L, Fischer T, Martin A, Muzamhindo C, Rhodes M, Smith J, Wagner J, Wood B, Becker D, Delallo K, Diaz A, Elnyczky B, Libman I, Pasek B, Riley K, Trucco M, Copemen B, Gwynn D, Toledo F, Rodriguez H, Bollepalli S, Diamond F, Eyth E, Henson D, Lenz A, Shulman D, Raskin P, Adhikari S, Dickson B, Dunnigan E, Lingvay I, Pruneda L, Ramos-Roman M, Raskin P, Rhee C, Richard J, Siegelman M, Sturges D, Sumpter K, White P, Alford M, Arthur J, Aviles-Santa M, Cordova E, Davis R, Fernandez S, Fordan S, Hardin T, Jacobs A, Kaloyanova P, Lukacova-Zib I, Mirfakhraee S, Mohan A, Noto H, Smith O, Torres N, Wherrett D, Balmer D, Eisel L, Kovalakovska R, Mehan M, Sultan F, Ahenkorah B, Cevallos J, Razack N, Ricci J, Rhode A, Srikandarajah M, Steger R, Russell W, Black M, Brendle F, Brown A, Moore D, Pittel E, Robertson A, Shannon A, Thomas J, Herold K, Feldman L, Sherwin R, Tamborlane W, Weinzimer S, Toppari J, Kallio T, Kärkkäinen M, Mäntymäki E, Niininen T, Nurmi B, Rajala P, Romo M, Suomenrinne S, Näntö-Salonen K, Simell O, Simell T, Bosi E, Battaglia M, Bianconi E, Bonfanti R, Grogan P, Laurenzi A, Martinenghi S, Meschi F, Pastore M, Falqui L, Muscato M, Viscardi M, Bingley P, Castleden H, Farthing N, Loud S, Matthews C, McGhee J, Morgan A, Pollitt J, Elliot-Jones R, Wheaton C, Knip M, Siljander H, Suomalainen H, Colman P, Healy F, Mesfin S, Redl L, Wentworth J, Willis J, Farley M, Harrison L, Perry C, Williams F. The Effect of Ethnicity in the Rate of Beta-Cell Functional Loss in the First 3 Years After Type 1 Diabetes Diagnosis. The Journal Of Clinical Endocrinology & Metabolism 2020, 105: dgaa348. PMID: 32502242, PMCID: PMC7531906, DOI: 10.1210/clinem/dgaa348.Peer-Reviewed Original ResearchConceptsMixed meal tolerance testNon-Hispanic whitesBMI z-scoreDiabetic ketoacidosisClinical diagnosisIntervention trialsImmunological characteristicsEffect of ethnicityFunctional lossC-peptide areaMeal tolerance testBody mass indexType 1 diabetesPositive clinical trialsExclusion of participantsAutoantibody positivityMass indexExperimental armTolerance testClinical trialsC-peptideObservational studyZ-scoreType 1Diagnosis
2019
Implantable wireless device for study of entrapment neuropathy
Malka R, Guarin D, Mohan S, Hernández I, Gorelik P, Mazor O, Hadlock T, Jowett N. Implantable wireless device for study of entrapment neuropathy. Journal Of Neuroscience Methods 2019, 329: 108461. PMID: 31626845, PMCID: PMC7325518, DOI: 10.1016/j.jneumeth.2019.108461.Peer-Reviewed Original ResearchConceptsAnimal modelsFunctional lossNeural dysfunctionGrade V injuriesFacial nerve functionSmall animal modelsPartial functional lossComplete functional lossWhisker displacementSurgical decompressionEntrapment syndromeDecompression surgeryNerve functionBell's palsyNerve damageFunctional recoveryGrade IIIFacial nervePeripheral nervesCompartment pressuresMurine modelDisease processInsufficient evidenceLive animal modelsOptimal timingAnalysis of genioglossus-centered tongue muscle function groups from dynamic magnetic resonance imaging
Xing F, Stone M, Goldsmith T, Prince J, Fakhri G, Woo J. Analysis of genioglossus-centered tongue muscle function groups from dynamic magnetic resonance imaging. The Journal Of The Acoustical Society Of America 2019, 146: 3086-3086. DOI: 10.1121/1.5137722.Peer-Reviewed Original ResearchMuscle functional groupsSpeech motor controlMotor controlInternal tongue musclesMuscle motionInternal musclesTongue muscle functionMuscle functionMuscle locationMotion patternsFunctional groupsMuscleDynamic magnetic resonance imagingFunctional lossDynamic magnetic resonanceMagnetic resonance imagingExtract motionCooperation patternsNormal controlsGenioglossusDigastric muscleUnique groupGroupResonance imagingClinical observationsAtlas-Based Tongue Muscle Correlation Analysis From Tagged and High-Resolution Magnetic Resonance Imaging.
Xing F, Stone M, Goldsmith T, Prince J, El Fakhri G, Woo J. Atlas-Based Tongue Muscle Correlation Analysis From Tagged and High-Resolution Magnetic Resonance Imaging. Journal Of Speech Language And Hearing Research 2019, 62: 2258-2269. PMID: 31265364, PMCID: PMC6808360, DOI: 10.1044/2019_jslhr-s-18-0495.Peer-Reviewed Original ResearchConceptsInternal tongue musclesFloor of mouthMagnetic resonance imagingHigh-resolution magnetic resonance imagingMuscle pairsTongue musclesRehabilitation strategiesSpeech sound productionResonance imagingCoordination patternsSpeech motor controlMuscle locationDisease populationMotion of muscleMotor controlIntersubjective behaviorsManually labeled masksMuscleGlossectomy patientsExtrinsic tongue musclesControl subjectsBloc movementFunctional lossPatientsMotion patterns
2018
An Atypical Presentation of Trauma-related Disorder in Geriatric Patients
Oyelakin A, Maksymenko A, Jegede O, Olupona T, Germain W, Jolayemi K. An Atypical Presentation of Trauma-related Disorder in Geriatric Patients. Journal Of Traumatic Stress Disorders & Treatment 2018, 2018 DOI: 10.4172/2324-8947.1000185.Peer-Reviewed Original ResearchPast psychiatric historyHistory of traumaYounger age groupsDSM-5 criteriaTraumatic eventsElderly patientsAtypical presentationGeriatric patientsClinical presentationComplicated presentationDefinitive diagnosisCase reportPsychiatric illnessMultiple traumatic eventsPsychiatric historyComorbid diagnosesPatientsCognitive impairmentAge groupsFunctional lossFurther evaluationConsiderable distressTraumaDisorganized behaviorDiagnosis
2015
Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin
Ambrosino P, Alaimo A, Bartollino S, Manocchio L, De Maria M, Mosca I, Gomis-Perez C, Alberdi A, Scambia G, Lesca G, Villarroel A, Taglialatela M, Soldovieri MV. Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin. Biochimica Et Biophysica Acta 2015, 1852: 1856-1866. PMID: 26073431, DOI: 10.1016/j.bbadis.2015.06.012.Peer-Reviewed Original ResearchBenign familial neonatal seizuresKv7.2/Kv7.3 channelsFunctional modulationPatch-clamp recordingsPotential therapeutic approachFamilial neonatal seizuresComplete functional lossNeonatal seizuresEpileptic encephalopathyPathogenetic mechanismsTherapeutic approachesChannel dysfunctionCaM affinityEpilepsy-causing mutationsKv7.3 channelsFunctional lossCaM overexpressionFunctional changesEpileptic diseasePhenotypic presentationChannel subunitsKCNQ2 geneKv7.2Significant alterationsC-terminal fragment
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