2024
Overview of Unilateral and Bilateral Pediatric Facial Paralysis: Workup, Treatment, and Frontiers
Wiebe J, Mulenga C, Crabtree J, Hussain A, Borschel G. Overview of Unilateral and Bilateral Pediatric Facial Paralysis: Workup, Treatment, and Frontiers. Facial Plastic Surgery 2024, 41: 410-416. PMID: 39209283, DOI: 10.1055/s-0044-1788994.Peer-Reviewed Original ResearchConceptsEtiology of facial nerve palsyFacial paralysisFacial nerve palsyFacial nerve paralysisNerve palsyIdiopathic causesSurgical managementTreatment optionsDifferential diagnosisNerve paralysisTreatment planningParalysisPermanent lossEtiologyTreatmentPsychosocial implicationsChildrenWorkupDiagnosis
2023
Facial Expression after Face Transplant: An International Face Transplant Cohort Comparison
Dorante M, Wang A, Kollar B, Perry B, Ertosun M, Lindford A, Kiukas E, Özkan Ö, Özkan Ö, Lassus P, Pomahac B. Facial Expression after Face Transplant: An International Face Transplant Cohort Comparison. Plastic & Reconstructive Surgery 2023, 152: 315e-325e. PMID: 36727808, DOI: 10.1097/prs.0000000000010242.Peer-Reviewed Original ResearchMeSH KeywordsFacial ExpressionFacial NerveFacial ParalysisFacial TransplantationFemaleHumansMaleSmilingSoftwareConceptsFT patientsHealthy controlsMotor function restorationMotor functionFace transplantFunction restorationAge-matched healthy controlsCLINICAL QUESTION/LEVELInterpositional nerve graftFull face transplantRespective healthy controlsMotor outcomeNerve coaptationFemale patientsNerve graftsPatientsPercentage restorationCohort comparisonFacial proceduresBilateral testsTransplantScore valuesFacial movements
2020
In Reply: The Utility of Intraoperative Lateral Spread Recording in Microvascular Decompression for Hemifacial Spasm: A Systematic Review and Meta-Analysis
Chang R, Reddy R, Altibi A, Iyengar P, Anetakis K, Crammond D, Balzer J, Sekula R, Thirumala P. In Reply: The Utility of Intraoperative Lateral Spread Recording in Microvascular Decompression for Hemifacial Spasm: A Systematic Review and Meta-Analysis. Neurosurgery 2020, 87: nyaa345-. PMID: 32761240, DOI: 10.1093/neuros/nyaa345.Peer-Reviewed Original ResearchLabel‐free histomorphometry of peripheral nerve by stimulated Raman spectroscopy
Hernández I, Yang W, Mohan S, Jowett N. Label‐free histomorphometry of peripheral nerve by stimulated Raman spectroscopy. Muscle & Nerve 2020, 62: 137-142. PMID: 32304246, DOI: 10.1002/mus.26895.Peer-Reviewed Original ResearchThe Utility of Intraoperative Lateral Spread Recording in Microvascular Decompression for Hemifacial Spasm: A Systematic Review and Meta-Analysis.
Thirumala P, Altibi A, Chang R, Saca E, Iyengar P, Reddy R, Anetakis K, Crammond D, Balzer J, Sekula R. The Utility of Intraoperative Lateral Spread Recording in Microvascular Decompression for Hemifacial Spasm: A Systematic Review and Meta-Analysis. Neurosurgery 2020, 87: e473-e484. PMID: 32297629, DOI: 10.1093/neuros/nyaa069.Peer-Reviewed Original ResearchConceptsLateral spread responseSpasm-free statusMicrovascular decompressionHemifacial spasmIntraoperative LSR monitoringClinical outcome of microvascular decompressionPersistence of lateral spread responseCranial nervesAbnormal lateral spread responseIntraoperative lateral spread responseLateral spread response monitoringResponse to facial nerve stimulationOutcome of microvascular decompressionAdequacy of decompressionFacial nerve stimulationMeta-analysisDiagnostic odds ratioPositive predictive valueSurgical treatmentClinical outcomesNerve stimulationOdds ratioWeb of ScienceHigh riskPredictive value
2019
Implantable wireless device for study of entrapment neuropathy
Malka R, Guarin D, Mohan S, Hernández I, Gorelik P, Mazor O, Hadlock T, Jowett N. Implantable wireless device for study of entrapment neuropathy. Journal Of Neuroscience Methods 2019, 329: 108461. PMID: 31626845, PMCID: PMC7325518, DOI: 10.1016/j.jneumeth.2019.108461.Peer-Reviewed Original ResearchConceptsAnimal modelsFunctional lossNeural dysfunctionGrade V injuriesFacial nerve functionSmall animal modelsPartial functional lossComplete functional lossWhisker displacementSurgical decompressionEntrapment syndromeDecompression surgeryNerve functionBell's palsyNerve damageFunctional recoveryGrade IIIFacial nervePeripheral nervesCompartment pressuresMurine modelDisease processInsufficient evidenceLive animal modelsOptimal timingAn Anatomic Variant of the Ansa Cervicalis Precluding Its Use as a Donor Nerve
Zhu A, Mohan S, Richmon J, Jowett N. An Anatomic Variant of the Ansa Cervicalis Precluding Its Use as a Donor Nerve. Annals Of Otology Rhinology & Laryngology 2019, 129: 78-81. PMID: 31510759, DOI: 10.1177/0003489419875975.Peer-Reviewed Original ResearchConceptsAnsa cervicalisAnatomic variantsVagus nerveParotid adenoid cystic carcinomaLeft vocal fold palsyCranial nerve repairFacial nerve resectionIpsilateral hypoglossal nerveRelevant anatomic variantsVocal fold palsyAdenoid cystic carcinomaInterposition repairDonor nerveNerve resectionSural nerveHypoglossal nerveInadvertent injuryNerve epineuriumCystic carcinomaGraft harvestNerve repairApparent morbidityNerveMuscle contractionCervicalisAnatomical Basis for Lip Reconstruction
Tong C, Vandegriend Z, Lee Y, Lawson W. Anatomical Basis for Lip Reconstruction. Annals Of Plastic Surgery 2019, Publish Ahead of Print: &na;. PMID: 30557180, DOI: 10.1097/sap.0000000000001642.Peer-Reviewed Original ResearchConceptsLower lip reconstructionLower lip depressorsLip reconstructionAnatomic basisLocoregional flapsFunctional lip reconstructionFresh cadaver studyKarapandzic flapUpper lip reconstructionBuccal branchFacial nerveDenervated tissueOrbicularis orisAnatomical basisCadaver studyMajor muscleZygomaticus major muscleFlapMuscular attachmentsOral apertureLarge defectsTransectionFan flapBuccinatorDepressor
2016
Discussion
Aycart M, Pomahac B. Discussion. Plastic & Reconstructive Surgery 2016, 137: 1898-1899. PMID: 27219243, DOI: 10.1097/prs.0000000000002207.Peer-Reviewed Original ResearchSurgical Optimization of Motor Recovery in Face Transplantation
Aycart M, Perry B, Alhefzi M, Bueno E, Kueckelhaus M, Fischer S, Pomahac B. Surgical Optimization of Motor Recovery in Face Transplantation. Journal Of Craniofacial Surgery 2016, 27: 286-292. PMID: 26967066, DOI: 10.1097/scs.0000000000002305.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolCleft LipCleft PalateCohort StudiesComorbidityCross InfectionFacial MusclesFacial NerveFacial TransplantationFemaleHospitals, PediatricHumansInfantInfant, NewbornMaleMotor NeuronsNerve TransferPlastic Surgery ProceduresPostoperative ComplicationsQuality ImprovementReoperationRetrospective StudiesRisk AdjustmentSmilingSurgical Wound InfectionConceptsMotor recoveryPatient 2Nerve transferNerve graftingPatient 1Devastating facial injuriesFacial nerve stumpFacial nerve reconstructionManual muscle testingFull face transplantIntraoperative soft tissueFacial nerve managementPrinciples of managementGradual improvementMuscle testingNerve reconstructionNerve stumpChallenging patientsMotor functionRetrospective analysisSensory restorationPatient's abilitySatisfactory motorFacial injuriesNerve management
2015
Surgical Anatomy of the Whole Facial Nerve for Enabling Craniofacial and Regenerative Medicine Translational Research in Swine
Aycart M, Alhefzi M, Bueno E, Pomahac B. Surgical Anatomy of the Whole Facial Nerve for Enabling Craniofacial and Regenerative Medicine Translational Research in Swine. Journal Of Reconstructive Microsurgery 2015, 31: 547-550. PMID: 26115545, DOI: 10.1055/s-0035-1555113.Peer-Reviewed Original ResearchGamma Knife radiosurgery for facial nerve schwannomas: a multicenter study.
Sheehan JP, Kano H, Xu Z, Chiang V, Mathieu D, Chao S, Akpinar B, Lee JY, Yu JB, Hess J, Wu HM, Chung WY, Pierce J, Missios S, Kondziolka D, Alonso-Basanta M, Barnett GH, Lunsford LD. Gamma Knife radiosurgery for facial nerve schwannomas: a multicenter study. Journal Of Neurosurgery 2015, 123: 387-94. PMID: 25955875, DOI: 10.3171/2014.11.jns141160.Peer-Reviewed Original ResearchConceptsFacial nerve schwannomaFacial nerve functionNorth American Gamma Knife ConsortiumHouse-Brackmann scoreStereotactic radiosurgeryNerve functionTumor controlNeurological preservationMargin doseMedian ageNerve schwannomaPreoperative facial nerve functionNormal facial nerve functionResidual/recurrent tumorActuarial tumor controlEffective salvage treatmentMean margin dosePermanent neurological symptomsTumor margin doseUpfront stereotactic radiosurgeryPatients' median ageMean tumor volumeTreatment of choiceGamma knife radiosurgeryRare intracranial tumors
2014
Hemifacial Spasm and Neurovascular Compression
Lu AY, Yeung JT, Gerrard JL, Michaelides EM, Sekula RF, Bulsara KR. Hemifacial Spasm and Neurovascular Compression. The Scientific World JOURNAL 2014, 2014: 349319. PMID: 25405219, PMCID: PMC4227371, DOI: 10.1155/2014/349319.Peer-Reviewed Original ResearchConceptsHemifacial spasmMicrovascular decompressionMagnetic resonance imagingSymptomatic reliefFacial nerveNerve root entry zonePrimary hemifacial spasmSecondary hemifacial spasmBotulinum neurotoxin injectionStandard medical managementTreatment of choiceFacial nerve rootRoot entry zoneIpsilateral facial nerveFacial nerve damageFacial movement disordersHFS patientsNerve damageVascular compressionCurative treatmentMedical managementNerve rootsNeurovascular compressionSurgical interventionClinical examinationNeuroblastoma Presenting as Facial Nerve Palsy and Bulging Tympanic Membrane
Bernson-Leung M, Ananth P, Shusterman S. Neuroblastoma Presenting as Facial Nerve Palsy and Bulging Tympanic Membrane. Clinical Pediatrics 2014, 54: 183-185. PMID: 24817076, DOI: 10.1177/0009922814534314.Peer-Reviewed Original Research
2012
Facial Composite Tissue Allograft
Pomahac B, Pribaz J. Facial Composite Tissue Allograft. Journal Of Craniofacial Surgery 2012, 23: 265-267. PMID: 22337422, DOI: 10.1097/scs.0b013e318241b8b8.Peer-Reviewed Original ResearchConceptsSuperficial temporal vesselsTemporal vesselsPeripheral facial nerve branchesComposite tissue allograftsFacial nerve branchesExternal auditory canalHair-bearing scalpComplete sensoryOcular ischemiaOropharyngeal dysfunctionNerve branchesAuditory canalFacial nerveDifficult dissectionTissue allograftsNerve connectionsPreauricular areaCarotid anastomosisMuscle insertionFacial vesselsFacial allograftFunctional problemsSoft tissueDissectionAllografts
2010
Vascular Considerations in Composite Midfacial Allotransplantation
Pomahac B, Lengele B, Ridgway E, Matros E, Andrews B, Cooper J, Kutz R, Pribaz J. Vascular Considerations in Composite Midfacial Allotransplantation. Plastic & Reconstructive Surgery 2010, 125: 517-522. PMID: 19910848, DOI: 10.1097/prs.0b013e3181c82e6f.Peer-Reviewed Original ResearchConceptsComposite tissue allograftsVascular considerationsTissue allograftsClinical casesFacial mimetic musclesComposite tissue transplantationFace transplant surgerySuccessful clinical caseAllograft revascularizationFrequent indicationMotor nervesTransplant surgeryFace allograftMotor functionBony canalGraft harvestHard palatePreclinical studiesRecipient vesselsClinical observationsFacial arteryTransplantationMimetic musclesAnastomotic networkTissue transplantation
2005
Localization of the Na+‐activated K+ channel Slick in the rat central nervous system
Bhattacharjee A, von Hehn CA, Mei X, Kaczmarek LK. Localization of the Na+‐activated K+ channel Slick in the rat central nervous system. The Journal Of Comparative Neurology 2005, 484: 80-92. PMID: 15717307, DOI: 10.1002/cne.20462.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAuditory PathwaysCentral Nervous SystemCHO CellsComputer SimulationCricetinaeDNA, ComplementaryFacial NerveImmunoblottingImmunohistochemistryIn Situ HybridizationKineticsModels, NeurologicalNeuronsOlfactory BulbPotassium ChannelsPotassium Channels, Sodium-ActivatedRatsReverse Transcriptase Polymerase Chain ReactionRNA ProbesSubcellular FractionsConceptsRat central nervous systemCentral nervous systemNervous systemAuditory neuronsCortical layers IIHigh-frequency stimulationLow-frequency firingDeep cerebellar nucleiSubstantia nigraTrapezoid bodyVestibular nucleiHippocampal CA1Dentate gyrusMedial nucleusCA3 regionOculomotor nucleusCertain neuronsFacial nucleusNeuronal nucleiOlfactory bulbPontine nucleiImmunohistochemical techniquesRed nucleusLayers IISupraoptic nucleus
1994
Prevalence of facial canal dehiscence and of persistent stapedial artery in the human middle ear: A report of 1000 temporal bones
Moreano E, Paparella M, Zelterman D, Goycoolea M. Prevalence of facial canal dehiscence and of persistent stapedial artery in the human middle ear: A report of 1000 temporal bones. The Laryngoscope 1994, 104: 309-320. PMID: 8127188, DOI: 10.1288/00005537-199403000-00012.Peer-Reviewed Original ResearchConceptsPersistent stapedial arteryFacial canal dehiscenceCanal dehiscenceTemporal boneStapedial arteryFacial canalPrevalence of bilateralityOval window areaVascular anomaliesCommon siteFirst histological studyHistological studyMiddle earPrevalenceDehiscenceArteryHuman middle earBoneCanalBilaterality
1992
Referred otalgia
Yanagisawa K, Kveton J. Referred otalgia. American Journal Of Otolaryngology 1992, 13: 323-327. PMID: 1443387, DOI: 10.1016/0196-0709(92)90072-2.Peer-Reviewed Original Research
1988
Hemifacial Spasm Caused by a Tortuous Vertebral Artery
Tash R, Kier E, Chyatte D. Hemifacial Spasm Caused by a Tortuous Vertebral Artery. Journal Of Computer Assisted Tomography 1988, 12: 492-494. PMID: 3366969, DOI: 10.1097/00004728-198805010-00027.Peer-Reviewed Original ResearchConceptsTortuous vertebral arteryInferior cerebellar arteryHemifacial spasmVertebral arteryFacial nerveBrain stemCerebellar arteryAnterior inferior cerebellar arteryPosterior inferior cerebellar arteryInternal auditory canalAxial T1-weighted imagesRoot exit zoneT1-weighted imagesMagnetic resonance (MR) appearanceCochlear arteryVertebrobasilar systemAuditory canalVascular loopsArterySpasmOrbicularis muscleNerveExit zoneFacial musclesResult of compression
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