2023
[18F]-fluoroethyl-L-tyrosine (FET) in glioblastoma (FIG) TROG 18.06 study: protocol for a prospective, multicentre PET/CT trial
Koh E, Gan H, Senko C, Francis R, Ebert M, Lee S, Lau E, Khasraw M, Nowak A, Bailey D, Moffat B, Fitt G, Hicks R, Coffey R, Verhaak R, Walsh K, Barnes E, De Abreu Lourenco R, Rosenthal M, Adda L, Foroudi F, Lasocki A, Moore A, Thomas P, Roach P, Back M, Leonard R, Scott A. [18F]-fluoroethyl-L-tyrosine (FET) in glioblastoma (FIG) TROG 18.06 study: protocol for a prospective, multicentre PET/CT trial. BMJ Open 2023, 13: e071327. PMID: 37541751, PMCID: PMC10407346, DOI: 10.1136/bmjopen-2022-071327.Peer-Reviewed Original ResearchConceptsFET PETPositron emission tomographyPrimary central nervous system cancerTumor progressionCentral nervous system cancerL-tyrosine positron emission tomographyFET-PET imagingPhase II studyCo-primary outcomesProgression-free survivalMaximal safe resectionPost-chemotherapy treatmentNervous system cancersHealth economic impactHuman Research Ethics CommitteePatterns of failureTrue tumor progressionGood clinical practiceDeclaration of HelsinkiRadiological progressionConcurrent chemoradiationInitial surgeryPostoperative radiotherapyII studyOverall survivalComparing Patient-Reported Outcomes Among Anti-TNF Experienced Patients With Ulcerative Colitis Initiating Vedolizumab Versus Tofacitinib
Kappelman M, Long M, Zhang X, Lin F, Weisbein L, Chen W, Burris J, Dorand J, Parlett L, Fehlmann T, Brensinger C, Haynes K, Nair V, Kaul A, Dobes A, Lewis J. Comparing Patient-Reported Outcomes Among Anti-TNF Experienced Patients With Ulcerative Colitis Initiating Vedolizumab Versus Tofacitinib. Crohn's & Colitis 360 2023, 5: otad031. PMID: 37350775, PMCID: PMC10284045, DOI: 10.1093/crocol/otad031.Peer-Reviewed Original ResearchUlcerative colitisIBD PartnersSecondary outcomesPain interferenceAnti-tumor necrosis factor therapyOutcomes Measurement Information System (PROMIS) domainsEffectiveness of vedolizumabNecrosis factor therapyCo-primary outcomesProspective cohort studyPatient-reported outcomesSocial role satisfactionSecondary nonresponseVedolizumab usersSecondary endpointsTreatment persistenceCohort studyFactor therapyTreatment initiationBiological therapyTreatment groupsPatientsLarger sample sizeTofacitinibVedolizumabPartial Meal Replacement for Weight Loss after Stroke: Results of a Pilot Clinical Trial
Dearborn Tomazos J, Viscoli C, Amin H, Lovelett L, Rivera J, Gull A, Kernan W. Partial Meal Replacement for Weight Loss after Stroke: Results of a Pilot Clinical Trial. Cerebrovascular Diseases 2023, 53: 54-61. PMID: 37231793, DOI: 10.1159/000530996.Peer-Reviewed Original ResearchRecent ischemic strokeBody mass indexIschemic strokeStandard carePMR groupWeight lossSC groupMeal replacementMean percent weight changePartial meal replacementOpen-label trialAcute ischemic strokeCo-primary outcomesHalf of patientsSuccessful weight lossPilot clinical trialPercent weight changeBMI 27Eligible patientsAdverse eventsObese patientsMass indexVascular inflammationLarge trialsFunctional outcomeComparing Patient-Reported Outcomes Among Anti-TNF-Experienced Patients with Crohn’s Disease Initiating Vedolizumab Versus Ustekinumab
Kappelman M, Lewis J, Zhang X, Lin F, Weisbein L, Chen W, Burris J, Dorand J, Parlett L, Haynes K, Nair V, Kaul A, Dobes A, Long M. Comparing Patient-Reported Outcomes Among Anti-TNF-Experienced Patients with Crohn’s Disease Initiating Vedolizumab Versus Ustekinumab. Digestive Diseases And Sciences 2023, 68: 3413-3420. PMID: 37115362, DOI: 10.1007/s10620-023-07942-0.Peer-Reviewed Original ResearchConceptsShort Crohn's Disease Activity IndexDisease activity indexCrohn's diseasePain interferenceCorticosteroid useTreatment persistenceSecondary outcomesAnti-tumor necrosis factor therapyOutcomes Measurement Information System (PROMIS) domainsCrohn's Disease Activity IndexEffectiveness of vedolizumabHigher corticosteroid useLower treatment persistenceNecrosis factor therapyCo-primary outcomesPatient-reported outcomesInternet-based cohort studyLogistic regression modelsIBD PartnersCohort studyExperienced patientsFactor therapyPrimary outcomeBiological therapySteroid use
2022
Validation of the Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) questionnaire for adults
Solmi M, Thompson T, Estradé A, Agorastos A, Radua J, Cortese S, Dragioti E, Leisch F, Vancampfort D, Thygesen L, Aschauer H, Schlögelhofer M, Aschauer E, Schneeberger A, Huber C, Hasler G, Conus P, Do Cuénod K, von Känel R, Arrondo G, Fusar-Poli P, Gorwood P, Llorca P, Krebs M, Scanferla E, Kishimoto T, Rabbani G, Skonieczna-Żydecka K, Brambilla P, Favaro A, Takamiya A, Zoccante L, Colizzi M, Bourgin J, Kamiński K, Moghadasin M, Seedat S, Matthews E, Wells J, Vassilopoulou E, Gadelha A, Su K, Kwon J, Kim M, Lee T, Papsuev O, Manková D, Boscutti A, Gerunda C, Saccon D, Righi E, Monaco F, Croatto G, Cereda G, Demurtas J, Brondino N, Veronese N, Enrico P, Politi P, Ciappolino V, Pfennig A, Bechdolf A, Meyer-Lindenberg A, Kahl K, Domschke K, Bauer M, Koutsouleris N, Winter S, Borgwardt S, Bitter I, Balazs J, Czobor P, Unoka Z, Mavridis D, Tsamakis K, Bozikas V, Tunvirachaisakul C, Maes M, Rungnirundorn T, Supasitthumrong T, Haque A, Brunoni A, Costardi C, Schuch F, Polanczyk G, Luiz J, Fonseca L, Aparicio L, Valvassori S, Nordentoft M, Vendsborg P, Hoffmann S, Sehli J, Sartorius N, Heuss S, Guinart D, Hamilton J, Kane J, Rubio J, Sand M, Koyanagi A, Solanes A, Andreu-Bernabeu A, Cáceres A, Arango C, Díaz-Caneja C, Hidalgo-Mazzei D, Vieta E, Gonzalez-Peñas J, Fortea L, Parellada M, Fullana M, Verdolini N, Andrlíková E, Janků K, Millan M, Honciuc M, Moniuszko-Malinowska A, Łoniewski I, Samochowiec J, Kiszkiel Ł, Marlicz M, Sowa P, Marlicz W, Spies G, Stubbs B, Firth J, Sullivan S, Darcin A, Aksu H, Dilbaz N, Noyan O, Kitazawa M, Kurokawa S, Tazawa Y, Anselmi A, Cracco C, Machado A, Estrade N, De Leo D, Curtis J, Berk M, Ward P, Teasdale S, Rosenbaum S, Marx W, Horodnic A, Oprea L, Alexinschi O, Ifteni P, Turliuc S, Ciuhodaru T, Bolos A, Matei V, Nieman D, Sommer I, van Os J, van Amelsvoort T, Sun C, Guu T, Jiao C, Zhang J, Fan J, Zou L, Yu X, Chi X, de Timary P, van Winkel R, Ng B, Pena E, Arellano R, Roman R, Sanchez T, Movina L, Morgado P, Brissos S, Aizberg O, Mosina A, Krinitski D, Mugisha J, Sadeghi-Bahmani D, Sheybani F, Sadeghi M, Hadi S, Brand S, Errazuriz A, Crossley N, Ristic D, López-Jaramillo C, Efthymiou D, Kuttichira P, Kallivayalil R, Javed A, Afridi M, James B, Seb-Akahomen O, Fiedorowicz J, Carvalho A, Daskalakis J, Yatham L, Yang L, Okasha T, Dahdouh A, Gerdle B, Tiihonen J, Shin J, Lee J, Mhalla A, Gaha L, Brahim T, Altynbekov K, Negay N, Nurmagambetova S, Jamei Y, Weiser M, Correll C. Validation of the Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) questionnaire for adults. Journal Of Affective Disorders 2022, 326: 249-261. PMID: 36586617, PMCID: PMC9794522, DOI: 10.1016/j.jad.2022.12.022.Peer-Reviewed Original ResearchConceptsConfirmatory factor analysisExploratory factor analysisCollaborative outcome studiesMeasure mental healthHealth and FunctioningFactor structureMental healthFactor analysisOutcome studiesFirst-order factorsExploratory factor analysis resultsHigh internal reliabilityObsessive-CompulsivePsychotic symptomsConcurrent validityInternal reliabilityAdult responsesCo-primary outcomesMeasure healthP-scoreCompanion questionnaireItemsHealthQuestionnairePost-traumaticA 10+10+30 radio campaign is associated with increased infant vaccination and decreased morbidity in Jimma Zone, Ethiopia: A prospective, quasi-experimental trial
Appiah B, Gebretsadik L, Mamo A, Kmush B, Asefa Y, France C, Samman E, Alemayehu T, Abafogi M, Ahmed M, Forastiere L, Singh G, Larsen D, Morankar S. A 10+10+30 radio campaign is associated with increased infant vaccination and decreased morbidity in Jimma Zone, Ethiopia: A prospective, quasi-experimental trial. PLOS Global Public Health 2022, 2: e0001002. PMID: 36962651, PMCID: PMC10021526, DOI: 10.1371/journal.pgph.0001002.Peer-Reviewed Original ResearchIntervention districtsRadio campaignCommunity radio stationsInfant vaccination coverageIntention-to-treatPer-protocol analysisDistrict clustersCommunity health workersInfluence health behaviorsJimma ZoneInfant morbidityQuasi-experimental trialVaccination coverageControl districtsPre-intervention differencesMass media interventionsRadio dramaRadio stationsDrama seriesCo-primary outcomesRandomized Controlled TrialsLow-income countriesHealth workersHealth behaviorsMedia interventionsThromboelastography-Guided Therapy Enhances Patient Blood Management in Cirrhotic Patients: A Meta-analysis Based on Randomized Controlled Trials
Hartmann J, Dias J, Pivalizza E, Garcia-Tsao G. Thromboelastography-Guided Therapy Enhances Patient Blood Management in Cirrhotic Patients: A Meta-analysis Based on Randomized Controlled Trials. Seminars In Thrombosis And Hemostasis 2022 DOI: 10.1055/s-0042-1757135.Peer-Reviewed Original ResearchPatient blood managementBlood productsAdult patientsAdverse eventsBlood managementIntensive care unit stayIndividual blood productsLess blood productsBlood product useCo-primary outcomesLong-term mortalityFresh frozen plasma unitsRisk of hemorrhageRandomized Controlled TrialsRegistered Systematic ReviewUse of thromboelastographyFrozen plasma unitsBleeding eventsFFP useUnit stayProduct transfusionTerm mortalityCirrhotic patientsCoagulation statusPlatelet useEffect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder
Oslin DW, Lynch KG, Shih MC, Ingram EP, Wray LO, Chapman SR, Kranzler HR, Gelernter J, Pyne JM, Stone A, DuVall SL, Lehmann LS, Thase ME, Aslam M, Batki S, Bjork J, Blow F, Brenner L, Chen P, Desai S, Dieperink E, Fears S, Fuller M, Goodman C, Graham D, Haas G, Hamner M, Helstrom A, Hurley R, Icardi M, Jurjus G, Kilbourne A, Kreyenbuhl J, Lache D, Lieske S, Lynch J, Meyer L, Montalvo C, Muralidhar S, Ostacher M, Paschall G, Pfeiffer P, Prieto S, Przygodzki R, Ranganathan M, Rodriguez-Suarez M, Roggenkamp H, Schichman S, Schneeweis J, Simonetti J, Steinhauer S, Suppes T, Umbert M, Vassy J, Voora D, Wiechers I, Wood A. Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder. JAMA 2022, 328: 151-161. PMID: 35819423, PMCID: PMC9277497, DOI: 10.1001/jama.2022.9805.Peer-Reviewed Original ResearchConceptsMajor depressive disorderPatient Health Questionnaire-9Usual care groupUsual carePharmacogenomic testingDrug-gene interactionsRemission rateMedication selectionCare groupDepressive disorderVeterans Affairs Medical CenterActive substance use disorderCo-primary outcomesPrescription of medicationsBetter clinical outcomesProportion of prescriptionsRemission of symptomsSubstance use disordersEligible patientsWeek 24Effective antidepressantSingle antidepressantClinical outcomesInitial treatmentQuestionnaire-90158 Risk perception, outcome expectancy, and treatment self-efficacy among women and men with obstructive sleep apnea (OSA)
Sharma A, Byrne S, Deng A, Chu J, Sands S, Wellman A, Redeke N, Yaggi H, Zinchuk A. 0158 Risk perception, outcome expectancy, and treatment self-efficacy among women and men with obstructive sleep apnea (OSA). Sleep 2022, 45: a73-a73. DOI: 10.1093/sleep/zsac079.156.Peer-Reviewed Original ResearchOutcome expectanciesContinuous positive airway pressureObstructive sleep apneaSub-scale scoresRisk perceptionSelf-efficacy measuresCPAP adherenceIndividual risk perceptionInsomnia Severity Index scoreCPAP therapyEffectiveness of CPAPNon-CPAP therapiesUnstable medical conditionsCo-primary outcomesFirst-line therapyPositive airway pressureApnea-hypopnea indexSeverity Index scoreEpworth Sleepiness ScalePerceptionSex differencesCPAP useOSA severityAirway pressureDaytime symptomsCompression stockings for treating vasovagal syncope (COMFORTS-II) trial: Rationale and design of a triple-blind, multi-center, randomized controlled trial
Tavolinejad H, Poopak A, Sadeghian S, Bozorgi A, Oraii A, Mollazadeh R, Emkanjoo Z, Kiarsi M, Shahabi J, Jalali A, Alaeddini F, Ariannejad H, Yadangi S, Oraii S, Kheirkhah J, Assadianrad M, Aminorroaya A, Tajdini M. Compression stockings for treating vasovagal syncope (COMFORTS-II) trial: Rationale and design of a triple-blind, multi-center, randomized controlled trial. American Heart Journal 2022, 249: 57-65. PMID: 35405100, DOI: 10.1016/j.ahj.2022.04.002.Peer-Reviewed Original ResearchConceptsElastic compression stockingsRandomized Controlled TrialsVasovagal syncopeProportion of participantsCompression stockingsTriple-blindLifestyle modification recommendationsVenous returnCo-primary outcomesPatient-reported adverse effectsTreat vasovagal syncopeVasovagal syncope recurrencesDiary sheetsSecondary outcomesStudy armsReduced venous returnSyncope recurrenceTrial backgroundSyncopal episodesFollow-upClinical trialsParticipantsMulti-centerOnline randomizationRecurrencePhase 2 Trial of Rituximab in Acetylcholine Receptor Antibody-Positive Generalized Myasthenia Gravis
Nowak RJ, Coffey CS, Goldstein JM, Dimachkie MM, Benatar M, Kissel JT, Wolfe GI, Burns TM, Freimer ML, Nations S, Granit V, Smith AG, Richman DP, Ciafaloni E, Al-Lozi MT, Sams LA, Quan D, Ubogu E, Pearson B, Sharma A, Yankey JW, Uribe L, Shy M, Amato AA, Conwit R, O'Connor KC, Hafler DA, Cudkowicz ME, Barohn RJ. Phase 2 Trial of Rituximab in Acetylcholine Receptor Antibody-Positive Generalized Myasthenia Gravis. Neurology 2022, 98: e376-e389. PMID: 34857535, PMCID: PMC8793103, DOI: 10.1212/wnl.0000000000013121.Peer-Reviewed Original ResearchPhase 2 trialPrednisone doseMean daily prednisone doseMulticenter phase 2 trialDaily prednisone doseSteroid sparing effectSteroid-sparing effectGeneralized myasthenia gravisCo-primary outcomesPhase 3 trialYears of agePlacebo regimenWeek 52Clinical improvementSecondary outcomesMyasthenia gravisPrimary outcomeLarge trialsSteroid useMean ageClinical assessmentEfficacy trialsSignificant worseningRituximabTargeted treatment
2021
Design of Behavioral Economic Applications to Geriatrics Leveraging Electronic Health Records (BEAGLE): A pragmatic cluster randomized controlled trial
Brown T, Rowe T, Lee J, Petito L, Chmiel R, Ciolino J, Doctor J, Fox C, Goldstein N, Kaiser D, Linder J, Meeker D, Peprah Y, Persell S. Design of Behavioral Economic Applications to Geriatrics Leveraging Electronic Health Records (BEAGLE): A pragmatic cluster randomized controlled trial. Contemporary Clinical Trials 2021, 112: 106649. PMID: 34896294, PMCID: PMC8724916, DOI: 10.1016/j.cct.2021.106649.Peer-Reviewed Original ResearchConceptsPrimary care clinicsProstate-specific antigenCo-primary outcomesElectronic health recordsCare clinicsOlder adultsClinician educationParallel armsPragmatic cluster-randomized trialNon-specific reasonsOvertreatment of diabetesClinical decision support interventionHealth recordsPrimary care cliniciansChoosing Wisely campaignLarge regional health systemCluster-randomized trialDecision support interventionsPragmatic clusterRegional health systemOlder patientsStudy armsCare cliniciansDiabetes measuresUrine testingEffect of sustained-release long-acting intravitreal dexamethasone implant in patients of non-proliferative diabetic retinopathy undergoing phacoemulsification: A randomized controlled trial
Gupta P, Ram J, Kumar M, Agarwal A, Gupta V, Singh R, Bansal R, Katoch D, Dogra M, Gupta A. Effect of sustained-release long-acting intravitreal dexamethasone implant in patients of non-proliferative diabetic retinopathy undergoing phacoemulsification: A randomized controlled trial. Indian Journal Of Ophthalmology 2021, 69: 3263-3272. PMID: 34708785, PMCID: PMC8725102, DOI: 10.4103/ijo.ijo_749_21.Peer-Reviewed Original ResearchConceptsEarly Treatment Diabetic Retinopathy StudyDexamethasone drug delivery systemStandard of careIntravitreal dexamethasone implantLaser flare meterDexamethasone implantIntraocular pressureOptical coherence tomographyMacular thicknessIntraocular lensDiabetic retinopathyDexamethasone groupTreatment Diabetic Retinopathy StudyNon-proliferative diabetic retinopathyStatistically significant interactionCentral macular thicknessIOP scoreDiabetic Retinopathy StudyStandard of care groupVisual acuity scoresType 2 diabetes mellitusRescue interventionCo-primary outcomesFlare meterMacular edemaPhysical and mental health impact of COVID-19 on children, adolescents, and their families: The Collaborative Outcomes study on Health and Functioning during Infection Times - Children and Adolescents (COH-FIT-C&A)
Solmi M, Estradé A, Thompson T, Agorastos A, Radua J, Cortese S, Dragioti E, Leisch F, Vancampfort D, Thygesen L, Aschauer H, Schloegelhofer M, Akimova E, Schneeberger A, Huber C, Hasler G, Conus P, Cuénod K, von Känel R, Arrondo G, Fusar-Poli P, Gorwood P, Llorca P, Krebs M, Scanferla E, Kishimoto T, Rabbani G, Skonieczna-Żydecka K, Brambilla P, Favaro A, Takamiya A, Zoccante L, Colizzi M, Bourgin J, Kamiński K, Moghadasin M, Seedat S, Matthews E, Wells J, Vassilopoulou E, Gadelha A, Su K, Kwon J, Kim M, Lee T, Papsuev O, Manková D, Boscutti A, Gerunda C, Saccon D, Righi E, Monaco F, Croatto G, Cereda G, Demurtas J, Brondino N, Veronese N, Enrico P, Politi P, Ciappolino V, Pfennig A, Bechdolf A, Meyer-Lindenberg A, Kahl K, Domschke K, Bauer M, Koutsouleris N, Winter S, Borgwardt S, Bitter I, Balazs J, Czobor P, Unoka Z, Mavridis D, Tsamakis K, Bozikas V, Tunvirachaisakul C, Maes M, Rungnirundorn T, Supasitthumrong T, Haque A, Brunoni A, Costardi C, Schuch F, Polanczyk G, Luiz J, Fonseca L, Aparicio L, Valvassori S, Nordentoft M, Vendsborg P, Hoffmann S, Sehli J, Sartorius N, Heuss S, Guinart D, Hamilton J, Kane J, Rubio J, Sand M, Koyanagi A, Solanes A, Andreu-Bernabeu A, Cáceres A, Arango C, Díaz-Caneja C, Hidalgo-Mazzei D, Vieta E, Gonzalez-Peñas J, Fortea L, Parellada M, Fullana M, Verdolini N, Fárková E, Janků K, Millan M, Honciuc M, Moniuszko-Malinowska A, Łoniewski I, Samochowiec J, Kiszkiel Ł, Marlicz M, Sowa P, Marlicz W, Spies G, Stubbs B, Firth J, Sullivan S, Darcin A, Aksu H, Dilbaz N, Noyan O, Kitazawa M, Kurokawa S, Tazawa Y, Anselmi A, Cracco C, Machado A, Estrade N, De Leo D, Curtis J, Berk M, Ward P, Teasdale S, Rosenbaum S, Marx W, Horodnic A, Oprea L, Alexinschi O, Ifteni P, Turliuc S, Ciuhodaru T, Bolos A, Matei V, Nieman D, Sommer I, van Os J, van Amelsvoort T, Sun C, Guu T, Jiao C, Zhang J, Fan J, Zou L, Yu X, Chi X, de Timary P, van Winke R, Ng B, Pena E, Arellano R, Roman R, Sanchez T, Movina L, Morgado P, Brissos S, Aizberg O, Mosina A, Krinitski D, Mugisha J, Sadeghi-Bahmani D, Sadeghi M, Hadi S, Brand S, Errazuriz A, Crossley N, Ristic D, López-Jaramillo C, Efthymiou D, Kuttichira P, Kallivayalil R, Javed A, Afridi M, James B, Seb-Akahomen O, Fiedorowicz J, Carvalho A, Daskalakis J, Yatham L, Yang L, Okasha T, Dahdouh A, Gerdle B, Tiihonen J, Shin J, Lee J, Mhalla A, Gaha L, Brahim T, Altynbekov K, Negay N, Nurmagambetova S, Jamei Y, Weiser M, Correll C. Physical and mental health impact of COVID-19 on children, adolescents, and their families: The Collaborative Outcomes study on Health and Functioning during Infection Times - Children and Adolescents (COH-FIT-C&A). Journal Of Affective Disorders 2021, 299: 367-376. PMID: 34606810, PMCID: PMC8486586, DOI: 10.1016/j.jad.2021.09.090.Peer-Reviewed Original ResearchConceptsHealth and FunctioningQuality of lifeCollaborative outcome studiesMental health impact of COVID-19Health impact of COVID-19Health of vulnerable childrenMental health of vulnerable childrenService utilization factorsEvidence-based interventionsWell-beingMental health impactsOutcome studiesCo-primary outcomesPromote HealthPhysical healthWHO-5Mental healthPhysical illnessCoping strategiesLimited social interactionAnonymous surveyParent ratingsFamily functioningSelf-ratingsHealthPeripheral levels of C-reactive protein, tumor necrosis factor-α, interleukin-6, and interleukin-1β across the mood spectrum in bipolar disorder: A meta-analysis of mean differences and variability
Solmi M, Suresh Sharma M, Osimo E, Fornaro M, Bortolato B, Croatto G, Miola A, Vieta E, Pariante C, Smith L, Fusar-Poli P, Shin J, Berk M, Carvalho A. Peripheral levels of C-reactive protein, tumor necrosis factor-α, interleukin-6, and interleukin-1β across the mood spectrum in bipolar disorder: A meta-analysis of mean differences and variability. Brain Behavior And Immunity 2021, 97: 193-203. PMID: 34332041, DOI: 10.1016/j.bbi.2021.07.014.Peer-Reviewed Original ResearchConceptsC-reactive proteinInflammatory mediator levelsTNF-aIL-6Meta-analysisSystematic review of observational studiesIL-1BSystematic reviewManic episodesReview of observational studiesBipolar disorderLow-quality studiesFull-text reviewMediator levelsDepressive episodeHealthy controlsBody mass indexCase-control studyCo-primary outcomesPhase of bipolar disorderMood spectrumTumor necrosis factor-aDisease activity stateDuration of illnessData extractionThe collaborative outcomes study on health and functioning during infection times in adults (COH-FIT-Adults): Design and methods of an international online survey targeting physical and mental health effects of the COVID-19 pandemic
Solmi M, Estradé A, Thompson T, Agorastos A, Radua J, Cortese S, Dragioti E, Leisch F, Vancampfort D, Thygesen L, Aschauer H, Schloegelhofer M, Akimova E, Schneeberger A, Huber C, Hasler G, Conus P, Cuénod K, von Känel R, Arrondo G, Fusar-Poli P, Gorwood P, Llorca P, Krebs M, Scanferla E, Kishimoto T, Rabbani G, Skonieczna-Żydecka K, Brambilla P, Favaro A, Takamiya A, Zoccante L, Colizzi M, Bourgin J, Kamiński K, Moghadasin M, Seedat S, Matthews E, Wells J, Vassilopoulou E, Gadelha A, Su K, Kwon J, Kim M, Lee T, Papsuev O, Manková D, Boscutti A, Gerunda C, Saccon D, Righi E, Monaco F, Croatto G, Cereda G, Demurtas J, Brondino N, Veronese N, Enrico P, Politi P, Ciappolino V, Pfennig A, Bechdolf A, Meyer-Lindenberg A, Kahl K, Domschke K, Bauer M, Koutsouleris N, Winter S, Borgwardt S, Bitter I, Balazs J, Czobor P, Unoka Z, Mavridis D, Tsamakis K, Bozikas V, Tunvirachaisakul C, Maes M, Rungnirundorn T, Supasitthumrong T, Haque A, Brunoni A, Costardi C, Schuch F, Polanczyk G, Luiz J, Fonseca L, Aparicio L, Valvassori S, Nordentoft M, Vendsborg P, Hoffmann S, Sehli J, Sartorius N, Heuss S, Guinart D, Hamilton J, Kane J, Rubio J, Sand M, Koyanagi A, Solanes A, Andreu-Bernabeu A, Cáceres A, Arango C, Díaz-Caneja C, Hidalgo-Mazzei D, Vieta E, Gonzalez-Peñas J, Fortea L, Parellada M, Fullana M, Verdolini N, Fárková E, Janků K, Millan M, Honciuc M, Moniuszko-Malinowska A, Łoniewski I, Samochowiec J, Kiszkiel Ł, Marlicz M, Sowa P, Marlicz W, Spies G, Stubbs B, Firth J, Sullivan S, Darcin A, Aksu H, Dilbaz N, Noyan O, Kitazawa M, Kurokawa S, Tazawa Y, Anselmi A, Cracco C, Machado A, Estrade N, De Leo D, Curtis J, Berk M, Ward P, Teasdale S, Rosenbaum S, Marx W, Horodnic A, Oprea L, Alexinschi O, Ifteni P, Turliuc S, Ciuhodaru T, Bolos A, Matei V, Nieman D, Sommer I, van Os J, van Amelsvoort T, Sun C, Guu T, Jiao C, Zhang J, Fan J, Zou L, Yu X, Chi X, de Timary P, van Winke R, Ng B, Pena E, Arellano R, Roman R, Sanchez T, Movina L, Morgado P, Brissos S, Aizberg O, Mosina A, Krinitski D, Mugisha J, Sadeghi-Bahmani D, Sadeghi M, Hadi S, Brand S, Errazuriz A, Crossley N, Ristic D, López-Jaramillo C, Efthymiou D, Kuttichira P, Kallivayalil R, Javed A, Afridi M, James B, Seb-Akahomen O, Fiedorowicz J, Carvalho A, Daskalakis J, Yatham L, Yang L, Okasha T, Dahdouh A, Gerdle B, Tiihonen J, Shin J, Lee J, Mhalla A, Gaha L, Brahim T, Altynbekov K, Negay N, Nurmagambetova S, Jamei Y, Weiser M, Correll C. The collaborative outcomes study on health and functioning during infection times in adults (COH-FIT-Adults): Design and methods of an international online survey targeting physical and mental health effects of the COVID-19 pandemic. Journal Of Affective Disorders 2021, 299: 393-407. PMID: 34949568, PMCID: PMC8288233, DOI: 10.1016/j.jad.2021.07.048.Peer-Reviewed Original ResearchConceptsCross-sectional surveyCollaborative outcome studiesSecondary outcomesHealth and FunctioningMental health effectsHealth care workersOutcome studiesHealth effectsLong-term interventionsCo-primary outcomesCOVID-19 pandemicInternational online surveyWHO-5Physical healthCare workersHigh-risk groupRepresentative samplePhysical disordersTreatment adherenceMental disordersCOVID-19HealthImpact of COVID-19Well-beingPre-COVID-19Outcomes of Allogeneic Hematopoietic Cell Transplantation in Patients With Myelofibrosis—A Systematic Review and Meta-Analysis
Bewersdorf JP, Sheth AH, Vetsa S, Grimshaw A, Giri S, Podoltsev NA, Gowda L, Tamari R, Tallman MS, Rampal RK, Zeidan AM, Stahl M. Outcomes of Allogeneic Hematopoietic Cell Transplantation in Patients With Myelofibrosis—A Systematic Review and Meta-Analysis. Transplantation And Cellular Therapy 2021, 27: 873.e1-873.e13. PMID: 34052505, PMCID: PMC8478722, DOI: 10.1016/j.jtct.2021.05.016.Peer-Reviewed Original ResearchConceptsConditioning regimen intensityAllo-HCTRegimen intensityChronic graftTransplant characteristicsGraft failureOverall survivalPatient ageSubgroup analysisDynamic International Prognostic Scoring System scoresSystematic reviewAllogeneic hematopoietic cell transplantationInternational Prognostic Scoring System scoreCurative therapeutic modalityNon-relapse mortalityTransplant-related mortalityMedian patient ageOutcomes of patientsSecondary graft failureCo-primary outcomesHematopoietic cell transplantHematopoietic cell transplantationRandomized clinical trialsHeterogeneity of patientsRandom-effects model
2019
Community Health Workers Improve Linkage to Hypertension Care in Western Kenya
Vedanthan R, Kamano JH, DeLong AK, Naanyu V, Binanay CA, Bloomfield GS, Chrysanthopoulou SA, Finkelstein EA, Hogan JW, Horowitz CR, Inui TS, Menya D, Orango V, Velazquez EJ, Were MC, Kimaiyo S, Fuster V. Community Health Workers Improve Linkage to Hypertension Care in Western Kenya. Journal Of The American College Of Cardiology 2019, 74: 1897-1906. PMID: 31487546, PMCID: PMC6788970, DOI: 10.1016/j.jacc.2019.08.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntihypertensive AgentsBlood PressureBlood Pressure DeterminationCluster AnalysisCommunicationCommunity Health ServicesCommunity Health WorkersFemaleHealth BehaviorHealth PromotionHealth Services AccessibilityHealth Services ResearchHumansHypertensionKenyaMaleMedication AdherenceMiddle AgedRisk FactorsSmartphoneSystoleTelemedicineConceptsCommunity health workersElevated blood pressureBlood pressureSystolic BPUsual careHealth workersHypertension careCovariate-adjusted mixed effects modelAverage overall followBaseline systolic BPHypertension care programCo-primary outcomesSystolic blood pressureSBP reductionHypertension controlOverall followSBP changeRisk factorsCare programLinkage of individualsCareMixed effects modelsGreater reductionMobile healthMortality
2018
Effect of a Multifaceted Quality Improvement Intervention on Hospital Personnel Adherence to Performance Measures in Patients With Acute Ischemic Stroke in China: A Randomized Clinical Trial
Wang Y, Li Z, Zhao X, Wang C, Wang X, Wang D, Liang L, Liu L, Wang C, Li H, Shen H, Bettger J, Pan Y, Jiang Y, Yang X, Zhang C, Han X, Meng X, Yang X, Kang H, Yuan W, Fonarow G, Peterson E, Schwamm L, Xian Y, Wang Y. Effect of a Multifaceted Quality Improvement Intervention on Hospital Personnel Adherence to Performance Measures in Patients With Acute Ischemic Stroke in China: A Randomized Clinical Trial. JAMA 2018, 320: 245-254. PMID: 29959443, DOI: 10.1001/jama.2018.8802.Peer-Reviewed Original ResearchConceptsMultifaceted quality improvement interventionAcute ischemic strokeQuality improvement interventionsEvidence-based performance measuresIschemic strokeImprovement interventionsControl groupUsual careClinical trialsIntervention groupEvidence-based stroke careCluster-randomized clinical trialClinical vascular eventsCo-primary outcomesLong-term outcomesHospital mortalityStroke RegistryVascular eventsSecondary outcomesPrimary outcomeStroke careCare protocolsClinical pathwayMAIN OUTCOMEPatients
2017
Comparison of Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Chronic Kidney Disease
Kumar N, Khera R, Garg N, Echouffo-Tcheugui JB, Venkatraman A, Pandey A, Bhatt DL. Comparison of Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Chronic Kidney Disease. The American Journal Of Cardiology 2017, 121: 343-348. PMID: 29268936, DOI: 10.1016/j.amjcard.2017.10.029.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve implantationDialysis-requiring acute kidney injuryAcute kidney injuryChronic kidney diseaseAortic valve replacementPostoperative strokeSAVR proceduresKidney diseaseHospital mortalityValve replacementTranscatheter Versus Surgical Aortic Valve ReplacementRate of AKIRetrospective cohort studySevere aortic stenosisCo-primary outcomesPropensity-matched pairsAortic valve implantationComparison of outcomesKidney injuryCohort studyValve implantationAortic stenosisMultivariate analysisPatients
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