2023
Do Clinical Outcomes and Quality of Life Differ by the Number of Antianginals for Stable Ischemic Heart Disease? Insights from the BARI 2D Trial
Jamil Y, Park D, Verde L, Sherwood M, Tehrani B, Batchelor W, Frampton J, Damluji A, Nanna M. Do Clinical Outcomes and Quality of Life Differ by the Number of Antianginals for Stable Ischemic Heart Disease? Insights from the BARI 2D Trial. The American Journal Of Cardiology 2023, 214: 66-76. PMID: 38160927, PMCID: PMC10923116, DOI: 10.1016/j.amjcard.2023.12.045.Peer-Reviewed Original ResearchStable ischemic heart diseaseAnti-anginal agentIntensive medical therapyIschemic heart diseaseMedical therapyQOL metricsHeart diseaseFindings merit further researchMajor adverse cardiovascular eventsAnti-anginal treatmentBARI 2D trialGreater QoL improvementAdverse cardiovascular eventsMyocardial jeopardy indexCardiovascular eventsCause mortalityCardiovascular endpointsClinical confoundersPatient characteristicsDiabetes mellitusHeart failureTherapy intensityClinical outcomesQOL improvementMyocardial infarctionUncovering the role of substance use in suicide attempts using a mixed‐methods approach
Diefenbach G, Stubbing J, Rice T, Lord K, Rudd M, Tolin D. Uncovering the role of substance use in suicide attempts using a mixed‐methods approach. Suicide And Life-Threatening Behavior 2023, 54: 70-82. PMID: 37987548, DOI: 10.1111/sltb.13019.Peer-Reviewed Original ResearchDrug use disordersLifetime suicide attemptsSuicide attemptsSubstance useRisk factorsSuicide attempt historyUse disordersAcute substance useCo-occurring alcoholAttempt historySubstance use contributesModifiable treatment targetSuicide risk factorsSuicide attempt methodClinical confoundersAdult inpatientsBaseline riskTreatment targetsTreatment planAttempt methodInpatientsAcute riskDisordersRiskStudy 2Differences in Mortality Among Patients With Asthma and COPD Hospitalized With COVID-19
Liu Y, Rajeevan H, Simonov M, Lee S, Wilson F, Desir G, Vinetz J, Yan X, Wang Z, Clark B, Possick J, Price C, Lutchmansingh D, Ortega H, Zaeh S, Gomez J, Cohn L, Gautam S, Chupp G. Differences in Mortality Among Patients With Asthma and COPD Hospitalized With COVID-19. The Journal Of Allergy And Clinical Immunology In Practice 2023, 11: 3383-3390.e3. PMID: 37454926, PMCID: PMC10787810, DOI: 10.1016/j.jaip.2023.07.006.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseType 2 inflammationCOVID-19 severitySOFA scoreAirway diseaseNoneosinophilic asthmaSequential Organ Failure Assessment scoreOrgan Failure Assessment scoreSevere coronavirus disease 2019Higher SOFA scoreMedian SOFA scoreRetrospective cohort studyObstructive pulmonary diseaseOdds of mortalityLower SOFA scoresCells/μLCOVID-19 outcomesCoronavirus disease 2019Logistic regression analysisCOVID-19Clinical confoundersAsthma patientsCohort studyImmunological factorsClinical features
2022
Nonselective beta blockers, hepatic decompensation, and mortality in cirrhosis: A national cohort study
Serper M, Kaplan DE, Taddei TH, Tapper EB, Cohen JB, Mahmud N. Nonselective beta blockers, hepatic decompensation, and mortality in cirrhosis: A national cohort study. Hepatology 2022, 77: 489-500. PMID: 35984731, PMCID: PMC9877112, DOI: 10.1002/hep.32737.Peer-Reviewed Original ResearchConceptsNonselective beta blockersSelective beta blockersLiver-related mortalityHepatic decompensationBeta blockersCTP classPlatelet countSubgroup analysisLiver disease etiologyLower hazardNational cohort studyNew-user designInverse probability treatmentRoutine clinical settingPrior decompensationViremia statusChild-TurcotteHCV viremiaClinical confoundersComposite outcomeCohort studyPrimary outcomeActive comparatorNational cohortDecompensation
2018
The association between psychotic experiences and traumatic life events: the role of the intention to harm
Moriyama T, Drukker M, Gadelha A, Pan P, Salum G, Manfro G, de Jesus Mari J, Miguel E, Rohde L, Polanczyk G, van Os J, Bressan R. The association between psychotic experiences and traumatic life events: the role of the intention to harm. Psychological Medicine 2018, 48: 2235-2246. PMID: 29331167, DOI: 10.1017/s0033291717003762.Peer-Reviewed Original ResearchConceptsTraumatic life eventsPsychotic experiencesLife eventsType of traumaTraumatic exposureTraumatic experiencesPositive associationMental healthTrauma categoriesChildren's exposureIntentionGreater levelsAccount potential confoundersMethods of assessmentExperiencePsychologistsBullyingAdolescentsDose of exposureTraumaStrong associationClinical confoundersBiasesDemographic characteristicsPotential confounders
2017
Racial and Ethnic Differences in Total Knee Arthroplasty in the Veterans Affairs Health Care System, 2001–2013
Hausmann LRM, Brandt CA, Carroll CM, Fenton BT, Ibrahim SA, Becker WC, Burgess DJ, Wandner LD, Bair MJ, Goulet JL. Racial and Ethnic Differences in Total Knee Arthroplasty in the Veterans Affairs Health Care System, 2001–2013. Arthritis Care & Research 2017, 69: 1171-1178. PMID: 27788302, PMCID: PMC5538734, DOI: 10.1002/acr.23137.Peer-Reviewed Original ResearchConceptsTotal knee arthroplastyKnee arthroplastyOA diagnosisHispanic-white differencesHispanic veteransVeterans Affairs Health Care SystemTotal knee arthroplasty (TKA) rateCox proportional hazards regressionTotal knee arthroplasty proceduresIncreased clinical severityKnee arthroplasty ratesPotential clinical confoundersPain intensity scoresProportional hazards regressionBody mass indexKnee arthroplasty proceduresEthnic differencesMusculoskeletal disorder diagnosisHealth care systemElectronic health recordsClinical confoundersHazards regressionMass indexRheumatology specialistsClinical severity
2016
Impact of Anemia on Platelet Reactivity and Ischemic and Bleeding Risk: From the Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents Study
Giustino G, Kirtane AJ, Baber U, Généreux P, Witzenbichler B, Neumann FJ, Weisz G, Maehara A, Rinaldi MJ, Metzger C, Henry TD, Cox DA, Duffy PL, Mazzaferri EL, Brodie BR, Stuckey TD, Gurbel PA, Dangas GD, Francese DP, Ozan O, Mehran R, Stone GW. Impact of Anemia on Platelet Reactivity and Ischemic and Bleeding Risk: From the Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents Study. The American Journal Of Cardiology 2016, 117: 1877-1883. PMID: 27131611, DOI: 10.1016/j.amjcard.2016.03.034.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnemiaAspirinBlood PlateletsClopidogrelCoronary Artery DiseaseDrug Therapy, CombinationDrug-Eluting StentsEuropeFemaleHemorrhageHumansIncidenceMaleMiddle AgedMyocardial IschemiaPercutaneous Coronary InterventionPlatelet AggregationPlatelet Aggregation InhibitorsProspective StudiesRegistriesRisk AssessmentRisk FactorsSurvival RateTiclopidineUnited StatesConceptsHigh platelet reactivityDrug-Eluting Stents studyMajor adverse cardiac eventsAdverse cardiac eventsDual antiplatelet therapyPlatelet reactivityAntiplatelet therapyMajor bleedingCause mortalityCardiac eventsMultivariate adjustmentStent studiesWorld Health Organization criteriaImpact of anemiaPresence of anemiaPercutaneous coronary interventionDrug-eluting stentsIschemic riskBleeding riskClinical confoundersCoronary interventionAnemic patientsClinical outcomesHemoglobin levelsStudy cohort
2014
Maternal Age and Risk of Labor and Delivery Complications
Cavazos-Rehg P, Krauss M, Spitznagel E, Bommarito K, Madden T, Olsen M, Subramaniam H, Peipert J, Bierut L. Maternal Age and Risk of Labor and Delivery Complications. Maternal And Child Health Journal 2014, 19: 1202-1211. PMID: 25366100, PMCID: PMC4418963, DOI: 10.1007/s10995-014-1624-7.Peer-Reviewed Original ResearchConceptsComplications of laborPoor fetal growthPregnant womenMaternal morbidityPreterm deliverySevere preeclampsiaFetal distressMild preeclampsiaFetal growthMaternal ageOlder womenGreater oddsUnited States Nationwide Inpatient SampleExtremes of ageNationwide Inpatient SampleYear old womanSeparate logistic regression modelsYears of ageRisk of laborLogistic regression modelsDelivery complicationsClinical confoundersPostpartum hemorrhageInpatient SampleSuch complications
2013
National psychotropic prescription dispensation among dually diagnosed patients
Marienfeld C, Rosenheck R. National psychotropic prescription dispensation among dually diagnosed patients. Advances In Dual Diagnosis 2013, 6: 34-44. DOI: 10.1108/17570971311309015.Peer-Reviewed Original ResearchAnalysis of covarianceNational Veterans Health AdministrationOutpatient mental health visitsMental health service useMental health visitsHealth service useVeterans Health AdministrationSevere mental illnessDrug-drug interactionsSchizophrenia spectrum disordersPrescription dispensationMedication classesClinic visitsClinical confoundersPharmacy recordsHealth visitsPsychotropic prescriptionsMood stabilizersPsychotropic medicationsMore prescriptionsHigh riskPatientsService useHealth AdministrationBipolar disorder
2004
Obesity and the Risk of New-Onset Atrial Fibrillation
Wang T, Parise H, Levy D, D’Agostino R, Wolf P, Vasan R, Benjamin E. Obesity and the Risk of New-Onset Atrial Fibrillation. JAMA 2004, 292: 2471-2477. PMID: 15562125, DOI: 10.1001/jama.292.20.2471.Peer-Reviewed Original ResearchConceptsBody mass indexNew-onset atrial fibrillationEchocardiographic left atrial diameterLeft atrial diameterAtrial fibrillationRisk factorsAtrial diameterBMI categoriesMass indexAF riskCommunity-based observational cohortNormal body mass indexAge-adjusted incidence ratesInterim myocardial infarctionCardiovascular risk factorsVentricular diastolic dysfunctionBaseline atrial fibrillationClinical risk factorsModifiable risk factorsInfluence of obesityDiastolic dysfunctionAtrial dilatationAtrial dimensionClinical confoundersHazard ratio
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