2022
Integrating responses to caregiver substance misuse, intimate partner violence and child maltreatment: Initiatives and policies that support families at risk for entering the child welfare system
Bosk E, Van Scoyoc A, Mihalec-Adkins B, Conrad A, Hanson K, Chaiyachati B. Integrating responses to caregiver substance misuse, intimate partner violence and child maltreatment: Initiatives and policies that support families at risk for entering the child welfare system. Aggression And Violent Behavior 2022, 65: 101637. DOI: 10.1016/j.avb.2021.101637.Peer-Reviewed Original ResearchIntimate partner violencePartner violenceChild maltreatmentConceptual paperChild welfare systemWelfare systemTransformative servicesPolicy optionsPrevention ActViolenceInnovative programsUnited StatesPractical discussionMaltreatmentSubstance misuseComplex traumaFundamental elementsPositive trajectoryInnovative approachCommon elementsTheoretical foundationPolicyIntegrative approachFamilyInitiatives
2017
Impact of Alternative Splicing on the Human Proteome
Liu Y, Gonzàlez-Porta M, Santos S, Brazma A, Marioni JC, Aebersold R, Venkitaraman AR, Wickramasinghe VO. Impact of Alternative Splicing on the Human Proteome. Cell Reports 2017, 20: 1229-1241. PMID: 28768205, PMCID: PMC5554779, DOI: 10.1016/j.celrep.2017.07.025.Peer-Reviewed Original ResearchConceptsProteomic diversityAlternative splicingAlternative splicing eventsDifferential transcript usageIntron retentionSplicing eventsHuman transcriptomeHuman proteomeTranscript usageRNA sequencingProtein abundanceTranscript levelsHuman diseasesProteomeSWATH-MSSplicingQuantitative snapshotIntegrative approachCritical determinantDiversityTranscriptomeSequencingAbundanceMRNAQuantitative mannerModeling of Receptor Tyrosine Kinase Signaling: Computational and Experimental Protocols
Fey D, Aksamitiene E, Kiyatkin A, Kholodenko BN. Modeling of Receptor Tyrosine Kinase Signaling: Computational and Experimental Protocols. Methods In Molecular Biology 2017, 1636: 417-453. PMID: 28730495, DOI: 10.1007/978-1-4939-7154-1_27.Peer-Reviewed Original ResearchConceptsReceptor tyrosine kinasesReceptor tyrosine kinase signalingMultiple cellular processesTyrosine kinase signalingCellular processesProtein phosphorylationKinase signalingNetwork biologySystems biologyTyrosine kinaseCell survivalIntegration of experimentsPowerful approachIntegrative approachBiologyComputational protocolQuantitative datasetsKinasePhosphorylationSignalingIdentification of salientApoptosisDifferentiationGlucose metabolismRegulation
2016
An integrative approach to investigate the respective roles of single-nucleotide variants and copy-number variants in Attention-Deficit/Hyperactivity Disorder
de Araújo Lima L, Feio-dos-Santos A, Belangero S, Gadelha A, Bressan R, Salum G, Pan P, Moriyama T, Graeff-Martins A, Tamanaha A, Alvarenga P, Krieger F, Fleitlich-Bilyk B, Jackowski A, Brietzke E, Sato J, Polanczyk G, Mari J, Manfro G, do Rosário M, Miguel E, Puga R, Tahira A, Souza V, Chile T, Gouveia G, Simões S, Chang X, Pellegrino R, Tian L, Glessner J, Hashimoto R, Rohde L, Sleiman P, Hakonarson H, Brentani H. An integrative approach to investigate the respective roles of single-nucleotide variants and copy-number variants in Attention-Deficit/Hyperactivity Disorder. Scientific Reports 2016, 6: 22851. PMID: 26947246, PMCID: PMC4780010, DOI: 10.1038/srep22851.Peer-Reviewed Original ResearchConceptsCopy number variantsProtein-protein interaction networkDe novo CNVsSingle nucleotide variantsGenetic architectureNew genesInteraction networksOnly geneFunctional analysisCNV studiesNovo CNVsGenesCell adhesionGenetic variantsExome dataIntegrative approachPathwayGenetic susceptibilityVariantsGWASTriosRespective rolesSilicoCNVsSNVs
2011
Mixed Methods Research Design for Pragmatic Psychoanalytic Studies
Tillman JG, Clemence AJ, Stevens JL. Mixed Methods Research Design for Pragmatic Psychoanalytic Studies. Journal Of The American Psychoanalytic Association 2011, 59: 1023-1040. PMID: 21880844, DOI: 10.1177/0003065111418650.Peer-Reviewed Original ResearchConceptsMixed methods researchMixed method research designMethods research designMethods researchResearch designComplex human phenomenaPsychoanalytic studyQuantitative research methodsHermeneutic endeavoursResearch methodologyHuman sciencesResearch methodsThird communityPragmatic approachHuman phenomenaEndeavorPast decadeQuantitative methodsIntegrative approachResearchDebateScienceCommunitySingle study designCalls
2008
A view from Riggs: treatment resistance and patient authority-IX. Integrative psychodynamic treatment of psychotic disorders.
Tillman JG. A view from Riggs: treatment resistance and patient authority-IX. Integrative psychodynamic treatment of psychotic disorders. Psychodynamic Psychiatry 2008, 36: 739-61. PMID: 19113964, DOI: 10.1521/jaap.2008.36.4.739.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntipsychotic AgentsAuthoritarianismCombined Modality TherapyDefense MechanismsFamily TherapyGriefHumansIndividuationInterpersonal RelationsLife Change EventsMalePsychoanalytic TheoryPsychoanalytic TherapyPsychotic DisordersSchizophreniaSchizophrenic PsychologyTransference, PsychologyConceptsPsychotic spectrum disordersSpectrum disorderTreatment-refractory patientsPsychodynamic treatment approachesRefractory patientsExtended case vignetteTreatment challengesTreatment resistancePsychosocial engagementPsychotic disordersTreatment approachesSchizoaffective disorderPatientsPsychological approachMental disordersPsychodynamic treatmentDisordersFamily systemTreatmentCase vignettesIntegrative approachEtiologySymptomsClinicians
1998
Ecologic Studies of Rodent Reservoirs: Their Relevance for Human Health - Volume 4, Number 4—December 1998 - Emerging Infectious Diseases journal - CDC
Mills J, Childs J. Ecologic Studies of Rodent Reservoirs: Their Relevance for Human Health - Volume 4, Number 4—December 1998 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 1998, 4: 529-537. PMID: 9866729, PMCID: PMC2640244, DOI: 10.3201/eid0404.980403.Peer-Reviewed Original Research
1995
Role-Relationship Models for Case Formulation
Horowitz M, Eells T, Singer J, Salovey P. Role-Relationship Models for Case Formulation. JAMA Psychiatry 1995, 52: 625-632. PMID: 7632110, DOI: 10.1001/archpsyc.1995.03950200015003.Peer-Reviewed Original ResearchConceptsRole relationship modelsCase formulationInterpersonal behavior patternsTerms of motivationDisorders of personalityIndividualized formulationMeans of configurationCore traitsSocial eventsPersonality disorderSymptom disorderBeliefsIntegrative approachApproaches of stateBehavior patternsSelfRelationship modelDisordersRecurrent elementsPersonalityAttributionDiverse selfMotivationRepetitionTreatment planning
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