Medical Research Scholars Program

2018-2019 MRSP Class
Left to Right: Omar Gonzalez, Samuel Dorry, Grant Allington, Christopher Ng, Carrie davison, Diana Du, Edel Aron, Andrew Takeda
The Medical Research Scholars Program (MRSP) at Yale University bridges barriers between traditional predoctoral and medical training by providing Yale Ph.D. students with both medically oriented coursework and a mentored clinical experience. The coursework provides a grounding in biomedicine, and the clinical experience enables students to interact with patients to learn firsthand about disease symptoms, treatment options, and the limitations of current therapies. This combination of medical knowledge and face-to-face interaction with patients and their doctors provides a new perspective to Ph.D. students and enhances the rigorous training in basic science already provided within the BBS Program. Upon completion of their training, MRSP graduates will be capable of working much more closely with physicians and physician-scientists and to independently perform clinically relevant basic research. Funding for the creation of the MRSP was provided by a grant from the Howard Hughes Medical Institute and is now supported by the Molecular Medicine Training Grant (T32GM100884) funded by the National Institute of General Medical Sciences.

Program Eligibility

The MRSP is open only to students who have already been accepted into the BBS Program, and an application is required. Eligible students will be invited to apply to the MRSP program and will be provided with the application details via e-mail. Approximately five first year students are enrolled each year and remain in the program for three years. They still remain in their BBS Tracks or Departments but participate in the additional MRSP curriculum.

The Curriculum

The MRSP curriculum consists of four classroom courses that focus first on normal human physiology and organ-based cell biology, followed by human pathobiology and then an introduction to drug discovery, validation and clinical trials (see table below). Some of these classes will be open to all BBS students, at the discretion of the course directors. The centerpiece of the MRSP is a two-year Mentored Clinical Experience that takes place during years two and three of the program and provides students with patient contact. Exposure to patients and to the practice of medicine will enable graduate students to work more confidently at the interface of research and medicine and facilitate future collaborations with clinical researchers. The Mentored Clinical Experience is open only to students formally enrolled as Medical Research Scholars. 

  


MRSP Curriculum Descriptions

Comprehensive descriptions of the above courses are available in Word by clicking here.

Year 1

Term Course Directors
Fall Physiological Systems M. Saltzman
Spring Systems Cell Biology A. Vignery
Summer Intro to Biostatistics J. Dziura, C. Brandt

Year 2

Term Course Directors

Pathobiology-choice of #1 or #2 below:
Fall    1) Molecular Mechanisms of Human Disease N. Wajapeyee
Fall & Spring    2) Medical Physiology Case Conference E. Boulpaep
Spring Topics in Human Investigation J. Craft, K. Anderson
Fall & Spring Mentored Clinical Experience E. Herzog, M. Caplan

Year 3

Term Course Directors
Fall & Spring Mentored Clinical Experience E. Herzog, M. Caplan
Fall Medical Physiology Case Conference

E. Boulpaep  


Program Leadership

The MRSP has two co-Directors, Michael Nitabach, Ph.D., J.D. and Anthony Koleske, Ph.D. Erica Herzog, M.D., Ph.D. and Michael Caplan, M.D., Ph.D. are Associate Directors. The administrative liaison for the MRSP is Bonnie Ellis, Student Services Officer for the BBS Program. The MRSP also has a core leadership team that includes the above individuals and John Alvaro, Karen Anderson, David Stern, Joe Craft, and Fred Gorelick.


Student Selection Process

The application deadline will be in mid-May. The MRSP application, along with the student’s Application for Admission to the Yale Graduate School, which was submitted for entry into the BBS Program, are reviewed by members of the MRSP core leadership team. Selection is based largely on the applicant’s responses on the MRSP application as well as on the applicant’s potential for successfully handling the demands of the MRSP curriculum on top of their regular BBS Track coursework and lab rotations. If necessary, students may be interviewed.

MRSP Application

Application deadline

2017-18 Medical Research Scholars
2017-2018 MRSP Class

From Left to Right: Erica Herzog, M.D., Ph.D., Associate Director, Jessica Shaklee, Alexander Koo, Ian Gonzalez, Oscar Chavez Ibanez, Caroline Focht, Noa Golan,  Erin DeNardo

The next application deadline will be in May of 2019.

Eligible students will be invited to apply via e-mail in April. 

Please direct all questions related to the application process to Bonnie Ellis.

For questions related to the Program and the curriculum, please contact John Alvaro.