Skip to Main Content

Autoimmunity, Allergy, & Transplantation

The immune response is tightly regulated to prevent and suppress reactivity to self and benign environmental stimuli, and the mechanisms by which these tolerance processes are maintained and cause disease when disrupted are studied in several laboratories. Additionally, immune responses to transplanted organs and ways to prevent and ameliorate graft rejection are active areas. Another major interest is in learning how specialized cells or anatomic locations, such as vascular endothelial cells or the brain, regulate and direct the immune response. Diseases being actively investigated include diabetes, multiple sclerosis, lupus, rheumatoid arthritis, allergy, celiac disease, and transplant rejection.