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Fred Sanford Gorelick, MD

Henry J. and Joan W. Binder Professor of Medicine (Digestive Diseases) and of Cell Biology; Director Investigated Gastroenterology NIH T32, Internal Medicine; Deputy Director, MD-PhD Program

Contact Information

Fred Sanford Gorelick, MD

Mailing Address

  • Yale School of Medicine

    Department of Medicine (Digestive Diseases), PO Box 208019

    New Haven, CT 06520-8019

    United States



After completing medical school and internal medicine training at the University of Missouri, Dr. Gorelick trained at Yale in Gastroenterology. After his clinical training, he began basic science training with Dr. James Jamieson at Yale. During that period he described calcium-calmodulin dependent protein kinase II and subsequently worked with Dr. Paul Greengard (Rockefeller University) to examine the enzyme's mechanism of activation, a response critical to neuronal memory.

His later work has focused on the mechanisms of acute pancreatits and how digestive enzymes, such as trypsin, are activated within the pancreas during this disease. Dr. Gorelick sees patients with gastrointestinal diseases at the VAMC in West Haven, CT. He is also the Deputy Director for the Yale physician Scientist program and directs a year-long course for the group that links basic science to clinical disease. He has also been the Director of the Yale Program in Investigative Gastroenterology for over 10 years. His laboratory at the VA studies the molecular mechanisms related to acute pancreatitis with a goal of developing tools that prevent or lessen disease.

Education & Training

  • Visiting Scientist
    Rockefeller University (2018)
  • Post Doctoral
    Yale University (1980)
  • GI Fellow
    Yale University School of Medicine (1979)
  • Resident
    University of Missouri (1976)
  • MD
    University of Missouri (1973)


  • Board Certification
    AB of Internal Medicine, Gastroenterology (1980)
  • Board Certification
    AB of Internal Medicine, Internal Medicine (1976)

Honors & Recognition

AwardAwarding OrganizationDate
Senior Clinical Scientist AwardVeterans Administration2019
Lifetime Mentorship AwardAmerican Gastroenterological Association2019
Research Mentor Award in Pancreatic DiseasesAmerican Gastroenterological Association2018
Henry J and Joan W Binder Professor of Medicine and Cell BiologyYale University2017
Howard Spiro Teaching AwardYale Section of Digestive Diseases2012
American Association of PhysiciansAAMC2010
William Go Life-time Achievement AwardAmerican Pancreatic Association2008
Bohmfalk Teaching Award in Basic ScienceYale University2007
Alvin Feinstein Clinical Mentor AwardYale School of Medicine2006
ASCIAmer Soc Clin Investigation1990
Morton Grossman Research AwardAmerican Gastroenterological Association1984

Professional Service

NIH NIDDKNIDDK Special emphasis study section: ZDK1 GRB-G 032020
Veterans AdministrationVeterans Administration Merit Award Section Section: Gastroenterology2020
NIH NIDDKZDK1 GRB-G 5 NIDDK special emphasis study section2018
NIH NIDDKZKDI GRB-3-J2 NIDDK Study Section: Chair2017
NIH-NIDDKSKUS-IRG special emphasis study section NIDDK2017
DOD PRMRP-P2rmis pancreasChaired grant review committee and reviewed grant submissions2012 - 2014
DOD P2RMISDigestive Disease Grant reviews2012 - 2014
NIHNIH ZDKi GRB-2 Study Section2009
Yale UniversityDeputy Director Yale MD, PhD Program2009 - 2013
Yale University School of MedicineDirector NIH T32 Training Program in Investigative Gastroenterology2005 - 2017
National Institutes of HealthNIH Study Section Chair (CIGP)2004 - 2006
NIH NIDDKFull-time member NIH GMA2 grant review committee2001 - 2004
American Pancreatic AssociationPresident1998 - 1999
American Gastroenterological Association Pancreatic SectionCo-chair then chair; organized pancreatic research and state of the art talks on pancreatic diseases for 4 day international meeting.1996 - 2000

Departments & Organizations