Research in the Track focuses on the molecular, cellular, and genetic underpinnings of immune system function and dysfunction during development, pathogen and microbiome encounter, cancer, genetic disease, and in a variety of autoimmune and inflammatory disorders. In addition to our growing efforts to advance basic science research that can be applied towards human disease, we have developed a Human Translational Immunology (HTI) Section to directly study human immunology and human diseases as a complementary lens to advance basic and translational immunology. Additionally, research in the Track benefits from numerous resources, collaborations, training, and synergies with centers and institutes that intersect with basic and human/translational immunology, including the Yale Center for Immuno-Oncology (YCIO), Colton Center for Autoimmunity at Yale (CCAY), Microbial Sciences Institute (MSI), Institute of Biomolecular Design and Discovery (IBDD), Center for Infection and Immunity (CII), and the Center for Systems and Engineering Immunology (CSEI). The general research interests of the Immunology Track break down into eight major themes, spanning almost all aspects of the immune system and its role in disease prevention.
The general research interests of the Immunology Track break down into seven major research themes, spanning almost all aspects of the immune system and its role in disease prevention, as described in the links above. Research within each of these themes employs a combination of cutting-edge methodologies leveraging not only mouse modeling but also a major emphasis on human immunology, systems immunology, and advanced imaging approaches.
Nearly forty laboratories are actively involved in research in immunology. Many share immediately adjoining or nearby laboratory space in The Anlyan Center (TAC), Amistad building, and 300 George Street building; and four faculty are funded by the Howard Hughes Medical Institute. Many of the faculty are in Yale’s Department of Immunobiology, which provides one of the largest integrated training programs in immunology in the country and which is led by a faculty with a reputation for excellence in research and dedication to mentorship, diversity, and inclusivity. The Department of Immunobiology maintains a wide variety of major equipment and benefits from cutting-edge core facilities supporting flow cytometry, genomics, genome engineering, imaging, and other applications.