2014
Electrocardiography changes in bipolar patients during long-term lithium monotherapy
Altinbas K, Guloksuz S, Caglar I, Caglar F, Kurt E, Oral E. Electrocardiography changes in bipolar patients during long-term lithium monotherapy. General Hospital Psychiatry 2014, 36: 694-697. PMID: 25091141, DOI: 10.1016/j.genhosppsych.2014.07.001.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntimanic AgentsArrhythmias, CardiacBipolar DisorderElectrocardiographyFemaleHumansLithium CompoundsMaleMiddle AgedConceptsTherapeutic serum levelsHealthy controlsSerum levelsLithium monotherapyLithium levelsEuthymic BD type I patientsBipolar disorderLong-term lithium useBD type I patientsCardiovascular side effectsChronic lithium treatmentSerum lithium levelsVentricular electrical instabilityType I patientsQT dispersion ratioUse of lithiumElectrocardiography changesI patientsBD patientsTherapeutic rangeLithium treatmentQRS intervalQT dispersionLithium useElectrocardiogram parameters
2012
Evidence for an association between tumor necrosis factor-alpha levels and lithium response
Guloksuz S, Altinbas K, Cetin E, Kenis G, Gazioglu S, Deniz G, Oral E, van Os J. Evidence for an association between tumor necrosis factor-alpha levels and lithium response. Journal Of Affective Disorders 2012, 143: 148-152. PMID: 22749155, DOI: 10.1016/j.jad.2012.04.044.Peer-Reviewed Original ResearchConceptsTNF-α levelsBipolar patientsLithium responsePartial responseTumor necrosis factor-alpha levelsBipolar disorderTreatment-resistant bipolar patientsNecrosis factor-alpha levelsRole of inflammationPotential pathophysiological mechanismsAdditional inflammatory markersAssessment of responseGood responseEnzyme-linked immunosorbentEuthymic bipolar patientsImmune imbalanceImmune alterationsInflammatory markersImmune changesPathophysiological mechanismsPotential confoundersLithium therapyNatural coursePoor responseTreatment response