Decoding protein binding landscape on circular RNAs with base-resolution transformer models
Wu H, Liu X, Fang Y, Yang Y, Huang Y, Pan X, Shen H. Decoding protein binding landscape on circular RNAs with base-resolution transformer models. Computers In Biology And Medicine 2024, 171: 108175. PMID: 38402841, DOI: 10.1016/j.compbiomed.2024.108175.Peer-Reviewed Original ResearchConceptsRNA-binding protein binding sitesRNA-binding proteinsCircRNA transcriptsBinding sitesBinding to RNA-binding proteinsSingle-nucleotide resolutionCovalent loop structureCircular RNAsBound nucleotideBinding motifBinding landscapeGene expressionTranscriptionRNANucleotideLoop structureCircRNAsProteinEndogenous RNAFragmentsSitesComputational methodsMotifGenesConvolutional neural network