Aymen Alian, MBChB
Associate Professor of AnesthesiologyCards
About
Research
Overview
Medical Research Interests
Anesthesiology; Laser-Doppler Flowmetry; Plethysmography
Publications
2024
Photoplethysmography Features Correlated with Blood Pressure Changes
Elgendi M, Jost E, Alian A, Fletcher R, Bomberg H, Eichenberger U, Menon C. Photoplethysmography Features Correlated with Blood Pressure Changes. Diagnostics 2024, 14: 2309. PMID: 39451632, PMCID: PMC11506471, DOI: 10.3390/diagnostics14202309.Peer-Reviewed Original ResearchTemporal domain featuresBlood pressure estimationPPG featuresBlood pressure predictionDomain featuresWearable devicesPhotoplethysmography signalsAcceleration photoplethysmogramPPG signalsPressure estimationPressure predictionPhotoplethysmography's featuresPhotoplethysmographyPredictor of systolic blood pressurePostpartum Blood Pressure Variability and Heart Rate Variability in Preeclampsia
van Wingerden A, Katsidoniotaki M, Haghighi N, Almonte C, Martinez H, Valdes E, Castro P, Alian A, Booker W, Bello N, Marshall R, Kougioumtzoglou I, Petersen N, Miller E. Postpartum Blood Pressure Variability and Heart Rate Variability in Preeclampsia. Hypertension 2024, 81: 2510-2519. PMID: 39403810, PMCID: PMC11578794, DOI: 10.1161/hypertensionaha.124.23321.Peer-Reviewed Original ResearchBlood pressure variabilityChronic hypertensionHeart rate variabilitySuperimposed preeclampsiaBlood pressurePressure variabilityProspective cohort of womenTime-domain heart rate variabilityAssociated with autonomic dysregulationCohort of womenRatio of heart rate variabilityHigh blood pressure variabilityRate variabilityPreeclampsia groupLow-/high-frequency ratioPostpartum patientsPostpartum controlsPreeclampsiaRR interval differencesProspective cohortHigh-frequency heart rate variabilityAutonomic dysregulationPostpartum womenFinger plethysmographyWeeks postpartumGraph connection Laplacian allows for enhanced outcomes of consumer camera based photoplethysmography imaging
Borik S, Wu H, Shelley K, Alian A. Graph connection Laplacian allows for enhanced outcomes of consumer camera based photoplethysmography imaging. Biomedical Signal Processing And Control 2024, 96: 106574. DOI: 10.1016/j.bspc.2024.106574.Peer-Reviewed Original ResearchRecommendations for evaluating photoplethysmography-based algorithms for blood pressure assessment
Elgendi M, Haugg F, Fletcher R, Allen J, Shin H, Alian A, Menon C. Recommendations for evaluating photoplethysmography-based algorithms for blood pressure assessment. Communications Medicine 2024, 4: 140. PMID: 38997447, PMCID: PMC11245506, DOI: 10.1038/s43856-024-00555-2.Peer-Reviewed Original Research
2023
A Prospective Cohort Study to Evaluate Needle Passes Using a Portable Ultrasound Device versus Traditional Landmark Approach for Epidural Anesthesia in a Busy Obstetric Tertiary Care Center
Fiol A, Rodriguez P, Zhao X, Gaiser R, Herrera A, Alian A. A Prospective Cohort Study to Evaluate Needle Passes Using a Portable Ultrasound Device versus Traditional Landmark Approach for Epidural Anesthesia in a Busy Obstetric Tertiary Care Center. POCUS Journal 2023, 8: 153-158. PMID: 38099155, PMCID: PMC10721287, DOI: 10.24908/pocus.v8i2.16298.Peer-Reviewed Original ResearchAssessment of changes in blood volume during lower body negative pressure-induced hypovolemia using bioelectrical impedance analysis
Anakmeteeprugsa S, Gonzalez-Fiol A, Vychodil R, Shelley K, Alian A. Assessment of changes in blood volume during lower body negative pressure-induced hypovolemia using bioelectrical impedance analysis. Journal Of Clinical Monitoring And Computing 2023, 38: 293-299. PMID: 37966562, DOI: 10.1007/s10877-023-01098-y.Peer-Reviewed Original ResearchEstimated blood lossBioelectrical impedance analysisBlood lossHealthy volunteersBlood volumeProspective observational studyBody negative pressureSignificant increaseT-testStudent's t-testAcute hemorrhageLBNP protocolLower extremitiesObservational studyHypovolemiaLBNPCompensatory mechanismsPercentage changeReciprocal changesSignificant decreaseBioimpedanceBaselineSignificant correlationMmHgP-valueSignal quality assessment of peripheral venous pressure
Chiu N, Chuang B, Anakmeteeprugsa S, Shelley K, Alian A, Wu H. Signal quality assessment of peripheral venous pressure. Journal Of Clinical Monitoring And Computing 2023, 38: 101-112. PMID: 37917210, DOI: 10.1007/s10877-023-01071-9.Peer-Reviewed Original ResearchSignal quality indexSignal qualityAdaptive non-harmonic modelSignal quality assessmentLower body negative pressure experimentsHigh qualityPressure experimentsSVM modelWaveformsPVP waveformsPressure waveformPeripheral venous pressure waveformsPVP segmentsOne-subject-out cross validationPowerPractical purposesPressureConvincing potentialContinuous non-invasive hemodynamic monitoring in early onset severe preeclampsia
Ackerman-Banks C, Bhinder J, Eder M, Heerdt P, Sugeng L, Testani J, Alian A, Lipkind H, Velazquez E, Reddy U, Chou J. Continuous non-invasive hemodynamic monitoring in early onset severe preeclampsia. Pregnancy Hypertension 2023, 34: 27-32. PMID: 37783090, DOI: 10.1016/j.preghy.2023.09.003.Peer-Reviewed Original ResearchConceptsTotal peripheral resistanceCardiac outputSevere preeclampsiaHemodynamic monitoringEarly-onset severe preeclampsiaProspective observational studyOnset severe preeclampsiaContinuous hemodynamic monitoringNon-invasive hemodynamic monitoringEarly preeclampsiaPregnant patientsPeripheral resistanceObservational studyPreeclampsiaLow mean biasDays postpartumNICOMModerate correlationPoor correlationMean biasAntepartumPatientsBaseline rotational thromboelastometry (ROTEM) values in a healthy, diverse obstetric population and parameter changes by pregnancy-induced comorbidities
Fiol A, Yoo J, Yanez D, Fardelmann K, Salimi N, Alian M, Mancini P, Alian A. Baseline rotational thromboelastometry (ROTEM) values in a healthy, diverse obstetric population and parameter changes by pregnancy-induced comorbidities. Baylor University Medical Center Proceedings 2023, 36: 562-571. PMID: 37614857, PMCID: PMC10443986, DOI: 10.1080/08998280.2023.2217534.Peer-Reviewed Original ResearchRotational thromboelastometryCoagulability statusObstetric populationROTEM valuesFIBTEM A10Elevated liver enzymesLow platelets (HELLP) syndromeMaximum clot firmnessClot formation timeBody mass indexPostpartum hemorrhage managementEXTEM A10Recent bleedingCesarean deliveryClot firmnessHypercoagulable profileGestational ageLiver diseasePostpartum hemorrhageRetrospective reviewMass indexBlack raceMaternal ageBlood productsHealthy criteriaUsing the ear photoplethysmographic waveform as an early indicator of central hypovolemia in healthy volunteers utilizing LBNP induced hypovolemia model
Eid A, Elgamal M, Gonzalez-Fiol A, Shelley K, Wu H, Alian A. Using the ear photoplethysmographic waveform as an early indicator of central hypovolemia in healthy volunteers utilizing LBNP induced hypovolemia model. Physiological Measurement 2023, 44: 055008. PMID: 37116503, DOI: 10.1088/1361-6579/acd165.Peer-Reviewed Original ResearchConceptsLower body negative pressureCentral hypovolemiaHealthy volunteersNon-invasive cardiac output monitorProgressive lower body negative pressureNoninvasive blood pressure monitorBody negative pressureCardiac output monitorBlood pressure monitorPhotoplethysmographic waveformPulse oximetry probeHypoperfusion symptomsSymptomatic subjectsHemodynamic indicesLBNP stageStroke volumeEarly predictorLT groupHypovolemiaEarly stagesPressure monitorWaveform indicesEarly indicatorWaveform morphologySymptoms
Clinical Care
Overview
Aymen Alian, MBChB (a medical degree awarded outside the U.S.), is an anesthesiologist who specializes in obstetric and gynecological anesthesiology.
Dr. Alian is an associate professor of anesthesiology at Yale School of Medicine and interim division chief for obstetrics and gynecologic anesthesiology. He studies cardiopulmonary and autonomic physiology and uses non-invasive monitors to detect central hypovolemia, a condition where there is decreased blood volume in the central circulatory system, during surgical procedures. Dr. Alian earned his medical degree from Zagazig University in Egypt. He completed his residency in anesthesiology at Yale New Haven Hospital and an internship at Griffin Hospital.
Clinical Specialties
Anesthesiology; Obstetric Anesthesiology
Fact Sheets
Pain Management for C-Sections
Learn More on Yale Medicine
Board Certifications
Anesthesiology
- Certification Organization
- AB of Anesthesiology
- Original Certification Date
- 2009
News
News
- October 31, 2022
Dr. Christine Won Elected President of Society of Anesthesiology and Sleep Medicine
- February 27, 2018
Dr. Aymen Alian receives two extramural grants to fund his research work.
- November 01, 2017
The Anesthesia department conducted a Ultrasound use for OB Anesthesiology workshop for residents and faculty on 11/05/2017
- January 31, 2017
STA 2017 Annual Meeting: Technology Advancing Perioperative Outcomes
Get In Touch
Contacts
Email
Appointment Number
Mailing Address
Anesthesiology
PO Box 208051, 333 Cedar Street, TMP 3
New Haven, CT 06520-8051
United States
Locations
Patient Care Locations
Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.