Aymen Alian, MBChB
Associate Professor of AnesthesiologyCards
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Division Chief, Obstetric & Gynecological Anesthesiology
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Anesthesiology
PO Box 208051, 333 Cedar Street, TMP 3
New Haven, CT 06520-8051
United States
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Division Chief, Obstetric & Gynecological Anesthesiology
Contact Info
Anesthesiology
PO Box 208051, 333 Cedar Street, TMP 3
New Haven, CT 06520-8051
United States
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Division Chief, Obstetric & Gynecological Anesthesiology
Contact Info
Anesthesiology
PO Box 208051, 333 Cedar Street, TMP 3
New Haven, CT 06520-8051
United States
About
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Titles
Associate Professor of Anesthesiology
Division Chief, Obstetric & Gynecological Anesthesiology
Biography
Dr. Alian is an Associate Professor of Anesthesiology, board certified anesthesiologist, clinical researcher and interim Division Chief for Obstetrics & Gynecologic Anesthesiology. Dr. Alian is a nationally recognized educator and has received several Faculty Awards of Excellence in education and mentorship. His clinical research is dedicated to the investigation of cardiopulmonary and autonomic physiology through the use of non-invasive monitors. Ongoing studies in Dr. Alian’s laboratory focuses on pulse oximetry and cerebral oximetry waveforms as sensitive biomarkers of central hypovolemia during anesthesia-surgery.
Appointments
Anesthesiology
Associate Professor on TermPrimary
Other Departments & Organizations
Education & Training
- Resident
- Yale-New Haven Hospital (2008)
- Intern
- Griffin Hospital (2005)
- MBChB
- Zagazig University (1991)
Research
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Overview
Medical Research Interests
ORCID
0000-0002-4810-8155
Research at a Glance
Yale Co-Authors
Publications Timeline
Kirk Shelley, MD, PhD
Kristen L. Fardelmann, MD
Angelique Garay
Nils Petersen, MD, PhD, MSc
Antonio Gonzalez-Fiol, MD
Katherine Kohari, MD, FACOG
Publications
2025
Aggregated postpartum cerebral autoregulatory curves in normotensive individuals, preeclampsia with severe features, and superimposed preeclampsia with severe features
Woolcock H, Katsidoniotaki M, Meng L, Haghighi N, van Wingerden A, Alian A, Booker W, Bello N, Marshall R, Kougioumtzoglou I, Petersen N, Miller E. Aggregated postpartum cerebral autoregulatory curves in normotensive individuals, preeclampsia with severe features, and superimposed preeclampsia with severe features. Physiological Measurement 2025, 46: 09nt01. PMID: 40845907, PMCID: PMC12441783, DOI: 10.1088/1361-6579/adfeb4.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsMean arterial pressureSuperimposed preeclampsiaPreeclampsia groupProspective observational studyNormotensive groupCerebral blood velocityRetrospective analysisPostpartum participantsAutoregulatory rangeRetrospective analysis of dataAutoregulatory curveContinuous mean arterial pressureImpaired cerebral autoregulationSevere featuresChronic hypertensionPreeclampsiaArterial pressureCerebral autoregulatory curveNormotensive individualsFinger plethysmographyPostpartum periodPair-wise comparisonsTranscranial DopplerAutoregulation curveCerebral autoregulationComparison of feature-based indices derived from photoplethysmogram recorded from different body locations during lower body negative pressure
Chand S, Chiu N, Chou Y, Alian A, Shelley K, Wu H. Comparison of feature-based indices derived from photoplethysmogram recorded from different body locations during lower body negative pressure. Physiological Measurement 2025, 46: 085002. PMID: 40712634, DOI: 10.1088/1361-6579/adf489.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsLower body negative pressureSensor locationsPhotoplethysmogram signalsTime-domain featuresPulse transit timeSensor placementSignal qualityPulse rateDiverse body sitesEar photoplethysmogramsPhotoplethysmogram sensorMeasurement locationsHealthy volunteersFinger photoplethysmogramDomain featuresPulse oximetry probeBaseline values for Quantra® QPlus® in healthy pregnant women at term and comparison to standard laboratory coagulation values: a prospective observational study
Anakmeteeprugsa S, Gonzalez-Fiol A, Garay A, Lin H, He Z, Alian A. Baseline values for Quantra® QPlus® in healthy pregnant women at term and comparison to standard laboratory coagulation values: a prospective observational study. BMC Pregnancy And Childbirth 2025, 25: 826. PMID: 40781663, PMCID: PMC12333236, DOI: 10.1186/s12884-025-07927-z.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsManagement of postpartum hemorrhageStandard laboratory coagulation testsPostpartum hemorrhageLaboratory coagulation testsCesarean deliveryPoint-of-care viscoelastic testingPregnant womenHealthy pregnant womenProspective observational studyCoagulation testsObservational studyMethodsHealthy pregnant womenSevere postpartum hemorrhageEarly recognitionElective cesarean deliveryPartial Pearson correlationsLabor groupFibrinogen levelsHealthy term pregnant womenTerm pregnant womenBaseline valuesAssociated with progressionAssessment of hemostasisPearson correlationInterquartile rangePhotoplethysmography imaging to assess facial perfusion under simulated hypovolemia
Borik S, Gilmore M, Gonzales-Fiol A, Biondi J, Wu H, Shelley K, Alian A. Photoplethysmography imaging to assess facial perfusion under simulated hypovolemia. Physiological Measurement 2025, 46: 075008. PMID: 40623433, DOI: 10.1088/1361-6579/adece3.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsSystemic vascular resistanceLower-body negative pressureHeart rate variabilityStroke volumeIntolerant groupMean arterial pressureHeart rate variability analysisVascular resistanceSV increaseArterial pressureSympathetic activityHR reductionProgressive hypovolemiaCardiovascular assessmentSimulated hypovolemiaEmergency settingAutonomic changesLF/HF ratioHealthy adultsPerfusion variationsAutonomic responsesHF powerHypovolemiaTolerance groupCritical careSpinal Sonography for Ultrasound-Guided Lumbar Neuraxial Anesthesia.
Gonzalez Fiol A, Pawan F, Alian A. Spinal Sonography for Ultrasound-Guided Lumbar Neuraxial Anesthesia. Journal Of Visualized Experiments 2025 PMID: 39960192, DOI: 10.3791/66901.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsSpine anatomyNeuraxial anesthesiaEpidural spaceCases of difficult anatomyLumbar spine anatomyNeuraxial ultrasonographyPreprocedural ultrasonographyNeuraxial techniquesSpinal sonographyDifficult anatomyRegular practiceAbnormal anatomyPalpation techniqueTraumatic procedureRegional anesthesiaUltrasonographyNeedle puncturePatientsSuccess rateAnesthesiaUltrasound techniqueAnatomyPractical tipsPalpationSeries of videosVital signs-based healthcare kiosks for screening chronic and infectious diseases: a systematic review
Bhutani S, Alian A, Fletcher R, Bomberg H, Eichenberger U, Menon C, Elgendi M. Vital signs-based healthcare kiosks for screening chronic and infectious diseases: a systematic review. Communications Medicine 2025, 5: 28. PMID: 39837977, PMCID: PMC11751283, DOI: 10.1038/s43856-025-00738-5.Peer-Reviewed Original ResearchCitationsAltmetricConceptsHealth kiosksHealthcare systemParticipant selectionUser experience evaluationResearch-to-practice gapOvercrowded emergency roomsDisease detectionHealthcare accessData reportingHealthcare deliveryStaff shortagesVital signsCardiovascular disease detectionResearch-to-practiceBackgroundIncreasing demandConclusionsThis reviewMeasure vital signsResultsThe findingsIEEE XploreGoogle Scholar databasesExperience evaluationSystematic reviewInclusion criteriaUser demographicsSystematic searchChapter 20 Postoperative pain management for cesarean delivery
Fiol A, McGuire P, Fardelmann K, Alian A. Chapter 20 Postoperative pain management for cesarean delivery. 2025, 213-221. DOI: 10.1016/b978-0-443-21707-4.00020-3.Peer-Reviewed Original Research
2024
Photoplethysmography Features Correlated with Blood Pressure Changes
Elgendi M, Jost E, Alian A, Fletcher R, Bomberg H, Eichenberger U, Menon C. Photoplethysmography Features Correlated with Blood Pressure Changes. Diagnostics 2024, 14: 2309. PMID: 39451632, PMCID: PMC11506471, DOI: 10.3390/diagnostics14202309.Peer-Reviewed Original ResearchCitationsConceptsTemporal domain featuresBlood pressure estimationPPG featuresBlood pressure predictionDomain featuresWearable devicesPhotoplethysmography signalsAcceleration photoplethysmogramPPG signalsPressure estimationPressure predictionPhotoplethysmography's featuresPhotoplethysmographyPredictor of systolic blood pressurePostpartum Blood Pressure Variability and Heart Rate Variability in Preeclampsia
van Wingerden A, Katsidoniotaki M, Haghighi N, Almonte C, Martinez H, Valdes E, Castro P, Alian A, Booker W, Bello N, Marshall R, Kougioumtzoglou I, Petersen N, Miller E. Postpartum Blood Pressure Variability and Heart Rate Variability in Preeclampsia. Hypertension 2024, 81: 2510-2519. PMID: 39403810, PMCID: PMC11578794, DOI: 10.1161/hypertensionaha.124.23321.Peer-Reviewed Original ResearchCitationsAltmetricConceptsBlood pressure variabilityChronic hypertensionHeart rate variabilitySuperimposed preeclampsiaBlood pressurePressure variabilityProspective cohort of womenTime-domain heart rate variabilityAssociated with autonomic dysregulationCohort of womenRatio of heart rate variabilityHigh blood pressure variabilityRate variabilityPreeclampsia groupLow-/high-frequency ratioPostpartum patientsPostpartum controlsPreeclampsiaRR interval differencesProspective cohortHigh-frequency heart rate variabilityAutonomic dysregulationPostpartum womenFinger plethysmographyWeeks postpartumGraph connection Laplacian allows for enhanced outcomes of consumer camera based photoplethysmography imaging
Borik S, Wu H, Shelley K, Alian A. Graph connection Laplacian allows for enhanced outcomes of consumer camera based photoplethysmography imaging. Biomedical Signal Processing And Control 2024, 96: 106574. DOI: 10.1016/j.bspc.2024.106574.Peer-Reviewed Original Research
Clinical Care
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Overview
Aymen Alian, MBChB (a medical degree awarded outside the U.S.), is an anesthesiologist who specializes in obstetric and gynecological anesthesiology.
Dr. Alian is an associate professor of anesthesiology at Yale School of Medicine and interim division chief for obstetrics and gynecologic anesthesiology. He studies cardiopulmonary and autonomic physiology and uses non-invasive monitors to detect central hypovolemia, a condition where there is decreased blood volume in the central circulatory system, during surgical procedures. Dr. Alian earned his medical degree from Zagazig University in Egypt. He completed his residency in anesthesiology at Yale New Haven Hospital and an internship at Griffin Hospital.
Clinical Specialties
Fact Sheets
Pain Management for C-Sections
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Board Certifications
Anesthesiology
- Certification Organization
- AB of Anesthesiology
- Original Certification Date
- 2009
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Contacts
Anesthesiology
PO Box 208051, 333 Cedar Street, TMP 3
New Haven, CT 06520-8051
United States
Locations
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Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.