Molecule
With support from the National Institutes of Health, electron microscopist Vinzenz Unger, associate professor of molecular biophysics and biochemistry, is determining the structure of biologically important molecules. This image depicts a three-dimensional reconstruction of a gap junction channel found in the human heart.
Federal
- Serap Aksoy, NIH, Evolutionary Genetics of Tsetse and its Symbionts, 5 years, $3,609,045
- Norma Andrews, NIH, Lysosome-Mediated Cell Invasion by Trypanosoma cruzi, 5 years, $2,549,132
- Lauren Cohn, NIH, Airway Inflammation-Related Inhibition of Disease (AIRID), 5 years, $1,654,270
- Joseph Craft, NIH, Dissecting the Role for IL-15 in CD8+ T Cell Homeostasis in Human Lupus, 5 years, $1,654,480
- Tore Eid, NIH, Dysregulation of Glutamine Synthetase in Human Temporal Lobe Epilepsy, 5 years, $866,750
- Peter Glazer, NIH, Hypoxia, Genetic Instability and DNA Mismatch Repair, 5 years, $1,853,968
- Jeffrey Gruen, NIH, Discovery of the 6p21.3 Reading Disability Gene, 3 years, $1,999,501
- Ya Ha, NIH, Structural Studies of Intramembrane Protease GlpG, 4 years, $1,256,220
- James Hebda, NIH, Investigating IAPP Aggregation and Toxicity Using Small Molecule Interference, 3 years, $91,673
- Mark Hochstrasser, NIH, Function and Assembly of Eukaryotic Proteasome, 4 years, $1,179,381
- Stanimir Ivanov, NIH, Analysis of F-Box Domain Containing Effector Proteins from Legionella pneumophila, 2 years, $96,472
- Leslie Jacobsen, NIH, Reward-Motivated Learning in Adolescent Cannabis Users, 2 years, $421,754
- James Leckman, NIH, rTMS For Adults with Severe Tourette Syndrome, 2 years, $423,620
- David McCormick, NIH, Properties of Axons and Synaptic Communication in the Neocortex, 4 years, $1,468,281
- Andrew Miranker, NIH, Fibrillogenesis Pathways in Diabetes and Renal Diseases, 1 year, $135,571
- Michael Nitabach, NIH, Calcium Signaling in Circadian Clock Neurons, 5 years, $1,763,529
- Justin Peacock, NIH, Arg Coordinates Contractile Forces with Adhesion Dynamics in Migrating Neurons, 3 years, $91,673
- John Rose, NIH, Development of VSV/HIV Recombinants as HIV Vaccines, 5 years, $1,654,500
- Gerald Shadel, NIH, Nuclear Control of Mitochondrial Gene Expression, 4 years, $1,489,032
- Richard Shiffman, Agency for Health Care Research and Quality (AHRQ), Clinical Decision Support Services, 2 years, $2,460,732
- Mehmet Sofuoglu, NIH, Human Laboratory Studies for Stimulant Addiction, 5 years, $631,800
- Uhna Sung, NIH, A Proteomic Analysis of Norepinephrine Transporters, 1 year, $75,206
- Elisabetta Ullu, NIH, Small RNAs and their Role in Trypanosome Biology, 5 years, $1,861,313
- Vinzenz Unger, NIH, Structural Biology of Presynaptic Scaffolds, 1 year, $165,292
Non-Federal
- Albert Ayoub, Robert Leet and Clara Guthrie Patterson Trust, Primitive Cortical Networks, 2 years, $106,000
- Allen Bale, Breast Cancer Alliance, Inc., Novel Chemopreventive Agents for Hereditary Breast Cancer, 1 year, $100,000
- Vineet Bhandari, American Thoracic Society, Role of Angiopoietin-2 in Hyperoxia-Induced Lung Injury in the Newborn, 2 years, $100,000
- Donald Botta, CoolSpine, LLC., Intraventricular Cooling Catheter, 1 year, $33,222
- Elizabeth Bradley, United Health Foundation, Hospital Variation in Survival Rates after Acute Myocardial Infarction, 3 years, $300,000; The Patrick and Catherine Weldon Donaghue Medical Research Foundation, Diffusion of Hospital Strategies to Improve Care for Heart Attacks: How and Why do Organizations Learn?, 1 year, $55,000
- Owen Chan, Juvenile Diabetes Research Foundation International, Role of GABA in Modulation of Counterregulatory Responses to Hypoglycemia, 2 years, $110,000
- Joseph Craft, Arthritis Foundation, A Novel T Cell Subset That Promotes Autoimmune Responses, 2 years, $200,000
- Larry Davidson, The Patrick and Catherine Weldon Donaghue Medical Research Foundation, Restoring Hope and Health to Adults with Serious Mental Illness, 3 years, $360,000
- Sabrina Diano, American Diabetes Association, Inc., Role of Arcuate AMPK on Energy Metabolism, 3 years, $300,000
- David Donnelly, Arkansas Children’s Hospital Research Institute, Postnatal Resetting of Carotid Chemoreceptor Sensitivity, 1 year, $347,277
- Eloise Dray, Susan G. Komen Breast Cancer Foundation, Molecular Basis of BRCA2-Mediated Repair of Chromosome Damage, 3 years, $135,000
- Naomi Driesen, The Patrick and Catherine Weldon Donaghue Medical Research Foundation, Prefrontal Development in Youths at Risk for Schizophrenia, 2 years, $239,956
- Michelle Erickson, College of American Pathologists Foundation, Evaluation of Usage Pattern of Fresh Frozen Plasma in a Tertiary Teaching Hospital Before and After an Interventional Program Initiated by the Transfusion Committee, 1 year, $9,545
- Matia Finn-Stevenson, Independence Public Schools, Evaluation Design of Three Middle-Childhood Before- and After-School Programs, 1 year, $45,000
- John Forrest, Doris Duke Charitable Foundation, Doris Duke Charitable Foundation Clinical Research Fellowship (CRF), 3.5 years, $900,000
- Qian Gao, American Diabetes Association, Inc., Crosstalk Between Estrogen and Leptin Signaling, 3 years, $300,000
- Nora Groce, Padua University Medical School, Investing for Health: Addressing the Social Determinants of Health, 2 months, $7,000
- Marsha Guess, Robert Wood Johnson Foundation, Vaginal Smooth Muscle Cell Differentiation in Pelvic Organ Prolapse, 4 years, $416,558
- Handan Gunduz-Bruce, National Alliance for Research on Schizophrenia and Depression, Modeling Glial Dysfunction in Psychotic and Mood Disorders, 2 years, $60,000
- Matija Hedl, Crohn’s & Colitis Foundation of America Inc., Nod2-Mediated Self-Tolerance and Cross-Tolerance to Toll-Like Receptors 2 and 4, 2 years, $57,447
- Robert Heimer, State of CT Dept. of Public Health, Preventing HIV and Other Infection by Expanding Syringe Access over the Counter and by Prescription, 2.5 years, $166,290
- Mark Horowitz, Maine Medical Center Research Institute, Mouse Models to Delineate a Unique Metabolic and Skeletal Network, 1 year, $144,644
- Tamas Horvath, Michael J. Fox Foundation for Parkinson’s Research, Ghrelin Protects Nigral Dopamine Cells, 1 year, $75,000
- Richard Kibbey, American Diabetes Association, Inc., Interaction of Mitochondrial GTP, Calcium and Anaplerotic Metabolism to Regulate Insulin Secretion, 3 years, $414,000
- Donald Lannin, Susan G. Komen Breast Cancer Foundation, Molecular Definition of DCIS that has Become Invasive, 2 years, $1,465,856
- Qiang Leng, American Heart Association, National Center, Identification, Characterization and Regulation of Intermediate Conductance 70 pS K Channel in Kidney, 4 years, $308,000
- Richard Lifton, Fondation Leducq, Transatlantic Network on Hypertension: Renal Salt Handling in the Control of Blood Pressure, 1 year, $3,000,000
- Yilun Liu, Breast Cancer Alliance, Inc., Understanding the Role of RAD51C Complexes in DNA Repair and Tumor Avoidance, 2 years, $125,000
- Paul Lombroso, Wesleyan University, Regulation of Epileptogenesis by STEP, 1 year, $16,089
- Jinyu Lu, American Cancer Society, Inc., Deciphering the Genetic Basis of Tumor Metastasis in Drosophila, 2 years, $94,000
- Shuangge Ma, University of Iowa, Regularized Classification and Survival Analysis for Expression Profiling of Cancer,
4 years, $306,420 - Mark Mamula, Juvenile Diabetes Research Foundation International, Post-Transitional Protein Modifications in
Diabetes Autoantigens, 1 year, $110,000 - Wang Min, AtheroGenics, Inc., Atherogenics Testing Agreement, 1 year, $19,860
- Yorgo Modis, The Lupus Research Institute, The Structural Basis of Endogenous Nucleic Acid Recognition by Toll-Like Receptors 7 and 9, 3 years, $300,000
- Alexander Neumeister, The Patrick and Catherine Weldon Donaghue Medical Research Foundation, Contribution of Life Trauma to the Neurobiology of Depression, 5 years, $467,110
- Jennifer Prah Ruger, The Patrick and Catherine Weldon Donaghue Medical Research Foundation, Ethics and Economics of Healthcare Disparities, 5 years, $595,796
- Lynne Regan, Breast Cancer Alliance, Inc., Novel Hsp90 Inhibitors as Potential Anti-Breast Cancer Agents, 1 year, $100,000
- Lei Song, National Organization for Hearing Research Foundation, Cable Properties of Outer Hair Cell Cylinder, 1 year, $20,000
- Mario Strazzabosco, PKD Foundation for Research in Polycystic Kidney Disease, Angiogenesis and Progression of Liver Cysts in ADPKD, 2 years, $150,000
- Mary Tinetti, John A. Hartford Foundation, Hartford Foundation Center of Excellence in Aging at Yale, 5 years, $750,000
- Christopher Tormey, College of American Pathologists Foundation, The Development of a Laboratory-Based Assay for the Identification and Evaluation of Transfusion Reactions, 1 year, $10,000
- Hong Wang, William J. Clinton Foundation, Expert Advice on Non-ARV Costs, China, 6 months, $27,500
- Tong Wang, Research Foundation of State University of New York, Cytoskeletal Mechanisms of the Epithelial Mesenchymal Transition Induced by the Receptor for Advanced Glycation End Products: The Role in Diabetic Kidney Disease, 1 year, $16,027
- Lauren Zenewicz, American Cancer Society, Inc., The Role of the Cytokine IL-22 in Liver Inflammation, 2 years, $94,000
- Edward Zigler, Foundation for Child Development, PCD Book, 1 year, $12,500
Featured in this article
- Serap Aksoy, PhD
- Tong Wang, MD
- Christopher Tormey, MD
- Mary Tinetti, MD
- Mario Strazzabosco, MD, PhD
- Lei Song, MD, PhD
- Mark Mamula, PhD
- Donald Lannin, MD
- Mark Horowitz, PhD
- Shuangge Steven Ma, PhD
- Richard Lifton, MD, PhD
- Matia Finn-Stevenson, PhD
- Naomi Driesen, PhD
- Edward Zigler, PhD
- Lynne Regan, PhD
- Paul Lombroso, MD
- Tamas Horvath, DVM, PhD
- Robert Heimer, PhD
- John Forrest Jr, MD
- Joseph Craft, MD
- Allen Bale, MD
- John Rose, PhD
- Andrew Miranker, PhD
- David McCormick, PhD
- James Leckman, MD, PhD
- Mark Hochstrasser, PhD
- Ya Ha, PhD
- Jeffrey R Gruen, MD
- Peter M. Glazer, MD, PhD
- Mehmet Sofuoglu, MD, PhD
- Richard Shiffman, MD
- Michael Nitabach, PhD, JD
- Tore Eid, MD, PhD
- Sabrina Diano, PhD
- Larry Davidson, PhD
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