2021
Three-Dimensional Osteosynthesis Plates for the Surgical Treatment of Mandibular Fractures
Khalil S, Khamis H, Kauke M, Iizuka T, Safi AF. Three-Dimensional Osteosynthesis Plates for the Surgical Treatment of Mandibular Fractures. Journal Of Craniofacial Surgery 2021, 32: e728-e735. PMID: 34172684, DOI: 10.1097/scs.0000000000007709.Peer-Reviewed Original ResearchConceptsAdditional surgical interventionMandibular fracturesPostoperative complicationsMajor complicationsRetrospective studySurgical interventionSystematic reviewPlate fractureAge of patientsEffective treatment modalityNumber of patientsRisk of biasComprehensive electronic searchCochrane HandbookSurgical treatmentClinical outcomesStability of osteosynthesisProspective studyWound dehiscenceOutcome parametersTreatment modalitiesMandible fracturesLower incidenceHigh riskFracture classification
2020
Effects of intraovarian injection of autologous platelet rich plasma on ovarian reserve and IVF outcome parameters in women with primary ovarian insufficiency
Cakiroglu Y, Saltik A, Yuceturk A, Karaosmanoglu O, Kopuk SY, Scott RT, Tiras B, Seli E. Effects of intraovarian injection of autologous platelet rich plasma on ovarian reserve and IVF outcome parameters in women with primary ovarian insufficiency. Aging 2020, 12: 10211-10222. PMID: 32507764, PMCID: PMC7346073, DOI: 10.18632/aging.103403.Peer-Reviewed Original ResearchConceptsAutologous platelet-rich plasmaPrimary ovarian insufficiencyPlatelet-rich plasmaIVF outcome parametersAntral follicle countIntraovarian injectionOvarian reservePRP injectionAntimullerian hormoneOutcome parametersOvarian insufficiencyRich plasmaSerum antimullerian hormoneUnderwent embryo transferExperimental treatment optionsESHRE criteriaSustained implantationOvarian stimulationSerum follicleFollicle countPRP treatmentTreatment optionsFertilization outcomeAntral folliclesEmbryo transferQuantification of contrast-uptake as imaging biomarker for disease progression of renal cell carcinoma after tumor ablation
Tegel BR, Huber S, Savic LJ, Lin M, Gebauer B, Pollak J, Chapiro J. Quantification of contrast-uptake as imaging biomarker for disease progression of renal cell carcinoma after tumor ablation. Acta Radiologica 2020, 61: 1708-1716. PMID: 32216452, PMCID: PMC7529766, DOI: 10.1177/0284185120909964.Peer-Reviewed Original ResearchMeSH KeywordsAblation TechniquesAdultAgedAged, 80 and overBiomarkers, TumorCarcinoma, Renal CellContrast MediaDisease ProgressionFemaleHumansImaging, Three-DimensionalKidney NeoplasmsMaleMiddle AgedNeoplasm StagingRadiography, InterventionalRetrospective StudiesSensitivity and SpecificityTumor BurdenUltrasonography, InterventionalConceptsProgression-free survivalTotal tumor volumeRenal cell carcinomaCell carcinomaOdds ratioTumor volumeImaging biomarkersImage-guided thermal ablationPrognosis of patientsRENAL nephrometry scoreCox regression modelLargest tumor diameterLog-rank testKaplan-Meier plotsCross-sectional imagingSensitive imaging biomarkerMetastatic diseaseSecondary outcomesPrimary outcomeDistant metastasisNephrometry scoreTumor diameterOutcome parametersLesion vascularityTNM stageCharacterization of Wnt signaling pathway (WSP) aberrations in advanced prostate cancer.
Ghali F, Patel D, Jamieson C, Parsons J, McKay R. Characterization of Wnt signaling pathway (WSP) aberrations in advanced prostate cancer. Journal Of Clinical Oncology 2020, 38: 203-203. DOI: 10.1200/jco.2020.38.6_suppl.203.Peer-Reviewed Original ResearchProstate cancerOverall survivalActivating mutationsDe novo metastatic diseaseAdvanced prostate cancerSomatic activating mutationsEligible patientsAdvanced diseaseGleason 8Visceral metastasesClinical characteristicsMetastatic diseaseOverall cohortMedian ageMedian timePCa patientsDisease characteristicsOutcome parametersCRPC developmentBiomarker statusDisease progressionMultiple malignanciesTreatment strategiesClinical significanceBRCA1/2 alterations
2019
Factor VIII prophylaxis effects outweigh other hemostasis contributors in predicting severe haemophilia A joint outcomes
Warren B, Jacobson L, Kempton C, Buchanan G, Recht M, Brown D, Leissinger C, Shapiro A, Abshire T, Manco‐Johnson M, Investigators F. Factor VIII prophylaxis effects outweigh other hemostasis contributors in predicting severe haemophilia A joint outcomes. Haemophilia 2019, 25: 867-875. PMID: 31115111, PMCID: PMC7273872, DOI: 10.1111/hae.13778.Peer-Reviewed Original ResearchConceptsFactor VIIITreatment armsGlobal assaysGlobal assays of coagulationFactor VIII half-lifeUnivariate logistic regression analysisFVIII half-lifeAged 6Treatment adherenceAssays of coagulationPresence of subchondral cystsProphylactic factor VIIILogistic regression analysisFVIII infusionHalf-lifeAssociation of variablesJoint-space narrowingHemophilia AUntreated childrenOutcome parametersSevere haemophiliaProphylaxis effectAnticoagulant proteinsLogistic regressionSubchondral cysts
2013
Cumulus and granulosa cell markers of oocyte and embryo quality
Uyar A, Torrealday S, Seli E. Cumulus and granulosa cell markers of oocyte and embryo quality. Fertility And Sterility 2013, 99: 979-997. PMID: 23498999, PMCID: PMC3866131, DOI: 10.1016/j.fertnstert.2013.01.129.Peer-Reviewed Original ResearchConceptsQuantitative reverse transcriptase-polymerase chain reactionGranulosa cell gene expressionRelevant outcome parametersReverse transcriptase-polymerase chain reactionTranscriptase-polymerase chain reactionMural granulosa cellsGranulosa cell markersBiomarkers of oocyteClinical benefitOutcome parametersWhole genome expression profilingGranulosa cellsOocyte qualityEmbryo qualityCell markersFollicular cellsNoninvasive meansCell gene expressionGenome expression profilingChain reactionEmbryo competenceMultitude of studiesOocytesTranscriptomic profilingExpression profiling
2003
Aortic Aneurysm Sac Shrinkage after Endovascular Repair Is Device-dependent: A Comparison of Zenith and AneuRx Endografts
Sternbergh W, Conners M, Tonnessen B, Carter G, Money S. Aortic Aneurysm Sac Shrinkage after Endovascular Repair Is Device-dependent: A Comparison of Zenith and AneuRx Endografts. Annals Of Vascular Surgery 2003, 17: 49-53. PMID: 12545252, DOI: 10.1007/s10016-001-0334-y.Peer-Reviewed Original ResearchConceptsAneurysm sac shrinkageEndovascular aneurysm repairSac shrinkageZenith groupZenith endograftSac diameterSac shrinkage rateSuccessful aneurysm exclusionAneurysm sac diameterComputed tomography measurementsAneuRx deviceAneuRx endograftEndovascular repairAneurysm exclusionAneurysm repairOutcome parametersSingle institutionMean reductionEndograftPatientsEndoleakObjective evidenceMonthsStatistical significanceHigh rate
2000
Impact of Guglielmi detachable coils on outcomes of patients with intracranial aneurysms treated by a multidisciplinary team at a single institution.
Sturaitis M, Rinne J, Chaloupka J, Kaynar M, Lin Z, Awad I. Impact of Guglielmi detachable coils on outcomes of patients with intracranial aneurysms treated by a multidisciplinary team at a single institution. Journal Of Neurosurgery 2000, 93: 569-80. PMID: 11014534, DOI: 10.3171/jns.2000.93.4.0569.Peer-Reviewed Original ResearchConceptsIntensive care unitInflation-adjusted hospital chargesHospital chargesClinical outcomesTherapeutic optionsIntracranial aneurysmsDuration of hospitalOutcomes of patientsPoor surgical risksAcademic referral centerLength of stayOverall management outcomeGuglielmi detachable coilsHigher clinical gradeEffectiveness of treatmentDisease severity parametersComputerized tomography scanningGDC procedureHospital stayIntradural aneurysmsReferral centerSurgical riskCare unitTertiary careOutcome parameters
1998
Arterial and venous Doppler velocimetry in the severely growth‐restricted fetus and associations with adverse perinatal outcome
Ozcan T, Sbracia M, d'Ancona R, Copel J, Mari G. Arterial and venous Doppler velocimetry in the severely growth‐restricted fetus and associations with adverse perinatal outcome. Ultrasound In Obstetrics And Gynecology 1998, 12: 39-44. PMID: 9697283, DOI: 10.1046/j.1469-0705.1998.12010039.x.Peer-Reviewed Original ResearchMeSH KeywordsBlood Flow VelocityCerebral ArteriesFemaleFetal Growth RetardationFetusHumansInfant, NewbornPregnancyPregnancy OutcomePrognosisPulsatile FlowReference ValuesSensitivity and SpecificitySignal Processing, Computer-AssistedSurvival RateUltrasonography, Doppler, ColorUltrasonography, PrenatalUmbilical ArteriesUmbilical VeinsConceptsAdverse outcome parametersAdverse perinatal outcomesGrowth-restricted fetusesOutcome parametersApgar scorePerinatal outcomesDuctus venosusPerinatal deathNeonatal intensive care unitSevere intrauterine growth restrictionDuctus venosus Doppler velocimetryAbnormal Doppler velocimetryVenous Doppler velocimetryVenous Doppler waveformsRespiratory distress syndromeMiddle cerebral arteryRetinopathy of prematurityIntensive care unitIntrauterine growth restrictionDays of lifeOnly significant parameterApgar valuesPeriventricular leukomalaciaDistress syndromeFetal demise
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