2025
Letter to the Editor: Effect of Nicotine Replacement Therapy on Perioperative Pain Management and Opioid Requirement in Abstinent Tobacco Smokers Undergoing Spinal Fusion: A Double-Blind Randomized Controlled Trial.
Costa G, De Aquino J. Letter to the Editor: Effect of Nicotine Replacement Therapy on Perioperative Pain Management and Opioid Requirement in Abstinent Tobacco Smokers Undergoing Spinal Fusion: A Double-Blind Randomized Controlled Trial. Journal Of Neurosurgical Anesthesiology 2025 PMID: 40325556, DOI: 10.1097/ana.0000000000001041.Peer-Reviewed Original ResearchNicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective
Ameral V, Sofuoglu M, Kelly M. Nicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective. Expert Review Of Clinical Pharmacology 2025, 18: 189-196. PMID: 40047379, PMCID: PMC11961306, DOI: 10.1080/17512433.2025.2472837.Peer-Reviewed Original ResearchSmoking cessationE-cigarettesEvidence-based clinical guidelinesEfficacy of e-cigarettesBenefits of e-cigarettesSmoking cessation treatmentHarm reduction optionsHarm reduction principlesNicotine replacement therapyNicotine e-cigarettesQuality of lifeIncreased life expectancyNicotine useCessation treatmentClinical guidelinesNicotineSmokingLife expectancyCigarette smokingClinical pharmacology perspectivePharmacological perspectiveClinical practiceHigh riskLong-term effectsReplacement therapyPilot study of a comprehensive multidisciplinary inpatient-based approach to smoking cessation in patients with vascular disease
Kim T, Brahmandam A, Alameddine D, Forman R, Hardik A, Fucito L, Mena-Hurtado C, Guzman R, Chaar C. Pilot study of a comprehensive multidisciplinary inpatient-based approach to smoking cessation in patients with vascular disease. JVS-Vascular Insights 2025, 3: 100174. DOI: 10.1016/j.jvsvi.2024.100174.Peer-Reviewed Original ResearchSmoking cessation ratesSmoking cessation programSmoking cessationCessation programsCessation ratesQuit smokingTeachable momentInpatient smoking cessation interventionsPatient-Reported Outcomes Measurement Information System questionnairesFree nicotine replacement therapyPilot studySmoking cessation counselingSmoking cessation interventionsProvider follow-upCarbon monoxide breath testNicotine replacement therapyCare of patientsQuality of lifeCessation counselingCessation interventionsInpatient strategiesVascular surgeryMental healthStop smokingCounseling sessions
2024
A randomized controlled trial evaluation of a smoking cessation and physical activity intervention delivered via telemedicine in the Norton Sound region of Alaska
Prochaska J, Vogel E, Oppezzo M, Skan J, Knox M, Chieng A, Crouch M, Aikens R, Schnellbaecher M, Benowitz N. A randomized controlled trial evaluation of a smoking cessation and physical activity intervention delivered via telemedicine in the Norton Sound region of Alaska. Addictive Behaviors 2024, 160: 108179. PMID: 39348775, PMCID: PMC11560622, DOI: 10.1016/j.addbeh.2024.108179.Peer-Reviewed Original ResearchModerate-to-vigorous physical activityMetabolic equivalent of taskNicotine replacement therapyNorton Sound regionPhysical activityModerate-to-vigorous physical activity guidelinesSelf-reported physical activity outcomesQuit smokingQuit attemptsNorton Sound region of AlaskaPhysical activity outcomesPhysical activity interventionsNicotine replacement therapy useAlaska Native peopleAlaska Native adultsRandomized controlled trial evaluationMetabolic equivalentsActivity outcomesActivity interventionsTelehealth counselingHealth interventionsTelemedicine counselingTobacco useMedication adherenceSmoking cessationA Pilot Study to Test the Feasibility of a Randomized Controlled Trial of E-cigarettes as Harm Reduction Tools Among People Who Smoke and Previously Failed to Quit With Pharmacotherapy
Smith T, Ferreira A, Wahlquist A, Cummings K, Rojewski A, McClure E, Toll B, Carpenter M. A Pilot Study to Test the Feasibility of a Randomized Controlled Trial of E-cigarettes as Harm Reduction Tools Among People Who Smoke and Previously Failed to Quit With Pharmacotherapy. Nicotine & Tobacco Research 2024, 27: 553-557. PMID: 39233579, DOI: 10.1093/ntr/ntae212.Peer-Reviewed Original ResearchRandomized Controlled TrialsE-cigarette groupE-cigarettesNRT groupPilot studyPoint prevalence abstinenceNicotine replacement therapyHarm reduction interventionsHarm reduction toolCombination nicotine replacement therapyTraditional pharmacotherapyTrial of e-cigarettesMean cigarettesReduction interventionsPrevalence abstinencePowered trialsControlled TrialsEffect sizeNon-whiteElectronic diaryCigarette smokersReplacement therapyParticipantsStandard pharmacotherapyDaily diariesPrescription of Nicotine Replacement Therapy for Hospitalized Tobacco Users
Nielsen E, Ware E, Heincelman M, Schreiner A, Lenert L, Toll B. Prescription of Nicotine Replacement Therapy for Hospitalized Tobacco Users. Southern Medical Journal 2024, 117: 517-520. PMID: 39094806, DOI: 10.14423/smj.0000000000001719.Peer-Reviewed Original ResearchConceptsNicotine replacement therapyPrescribed nicotine replacement therapyPrescription of nicotine replacement therapyNicotine replacement therapy prescriptionManagement of chronic conditionsHospitalized tobacco usersInitiate health behavior changeHealth behavior changeEmergency department visitsRate of prescriptionTobacco treatmentIncreased readmission ratesChronic conditionsHealth systemDepartment visitsRetrospective cohort studySmoking cessationTobacco usersInpatient admissionsReplacement therapyOutpatient settingCohort studyReadmission ratesSignificantly lower ratesCigarette smokingUrgent need for treatment addressing co-use of tobacco and cannabis: An updated review and considerations for future interventions
Nguyen N, Bold K, McClure E. Urgent need for treatment addressing co-use of tobacco and cannabis: An updated review and considerations for future interventions. Addictive Behaviors 2024, 158: 108118. PMID: 39089194, PMCID: PMC11365784, DOI: 10.1016/j.addbeh.2024.108118.Peer-Reviewed Original ResearchCo-useIntervention componentsAdvance health equityCannabis co-useMulti-component interventionCognitive behavioral therapyCo-use of tobaccoUse of tobaccoClinical practice guidelinesPublished intervention studiesNicotine replacement therapyHealth equityBehavioral therapyPriority populationsContingency managementMotivational interviewingPharmacotherapy strategiesUpdate previous reviewsTreatment studiesCompensatory useIn-personIntervention studiesPractice guidelinesCannabisYoung adultsNicotine Use Disorder
Khan A, Tampi R, Tampi D. Nicotine Use Disorder. 2024, 227-239. DOI: 10.1007/978-3-031-55711-8_16.Peer-Reviewed Original ResearchOlder adultsNicotine use disorderCombination of pharmacotherapyCessation interventionsNicotine replacement therapyRelapse preventionUse disorderBehavioral interventionsRelapsing conditionQuit smokingPopulation of older adultsSmoking cessationFood and Drug AdministrationNicotineReplacement therapyAdultsDrug AdministrationEffective cessation interventionsTobacco useInterventionRelapseBupropionVareniclinePharmacotherapyCessationDiscordance Between Insurance Coverage of Antiviral Medications and Nicotine Replacement Therapy Among Individuals With Human Immunodeficiency Virus Who Smoke
Bernstein S, Yager J, Sigel K, Porter E, Do T, Payne E, Bold K, Ledgerwood D, Edelman E. Discordance Between Insurance Coverage of Antiviral Medications and Nicotine Replacement Therapy Among Individuals With Human Immunodeficiency Virus Who Smoke. Journal Of Addiction Medicine 2024, 18: 404-407. PMID: 38606851, PMCID: PMC11290992, DOI: 10.1097/adm.0000000000001302.Peer-Reviewed Original ResearchNicotine replacement therapyHuman immunodeficiency virusTobacco use disorderAntiretroviral therapyReplacement therapyTobacco useImmunodeficiency virusCoverage of antiretroviral therapyInsurance coverageSecondary analysis of dataUse disorderManaged care planOut-of-pocketMandated insurance coverageCare planningEfficacy of antiviralsRandomized clinical trialsPharmacy benefit managersInsurance barriersMedication prescriptionsSecondary analysisTracking formParticipation AssessmentAntiviral medicationsPWH
2023
Effectiveness of smoking cessation interventions among pregnant women: An updated systematic review and meta-analysis
Vila-Farinas A, Pérez-Rios M, Montes-Martinez A, Ruano-Ravina A, Forray A, Rey-Brandariz J, Candal-Pedreira C, Fernández E, Casal-Acción B, Varela-Lema L. Effectiveness of smoking cessation interventions among pregnant women: An updated systematic review and meta-analysis. Addictive Behaviors 2023, 148: 107854. PMID: 37683574, DOI: 10.1016/j.addbeh.2023.107854.Peer-Reviewed Original ResearchNicotine replacement therapyRandomized clinical trialsLong-term nicotine replacement therapyPregnant womenCessation interventionsSystematic reviewSocioeconomic statusNon-pharmacological interventionsEffectiveness of pharmacologicalRisk of biasRoB 2 toolLow socioeconomic statusHigher socioeconomic statusPrimary search strategyHeavy smokersRoutine careReplacement therapySmoking cessationPharmacologic interventionsClinical trialsEligible studiesSTUDY APPRAISALDaily smokersEligibility criteriaPsychosocial interventionsImpact of Nicotine Replacement Therapy on Breast Surgery Outcomes
Patel S, Junn A, Sasson D, Dinis J, Duan K, Islam S, Fucito L, Bernstein S, Hsia H. Impact of Nicotine Replacement Therapy on Breast Surgery Outcomes. Journal Of Reconstructive Microsurgery 2023, 40: 239-244. PMID: 37467771, DOI: 10.1055/a-2133-1130.Peer-Reviewed Original ResearchNicotine replacement therapyNRT usageNRT useSurgical complicationsCessation therapyBreast surgeryReplacement therapyEffect of NRTYale New Haven Health SystemMultivariable logistic regression modelBreast surgery outcomesTobacco smoke intakeRetrospective chart reviewType of surgeryBody mass indexSmoking cessation therapyLogistic regression modelsPostoperative complicationsChart reviewPostoperative outcomesSmoke intakeComplication dataMass indexSmoking statusFat necrosisImpact of a Multidisciplinary Curriculum Training Students and Residents in Tobacco Cessation Strategies for Adult Caregivers of Children
Gribben V, Chang A, Ling P, Rasmussen J, Tebb K, Fuentes-Afflick E, Marbin J. Impact of a Multidisciplinary Curriculum Training Students and Residents in Tobacco Cessation Strategies for Adult Caregivers of Children. MedEdPORTAL 2023, 19: 11313. PMID: 37228253, PMCID: PMC10203095, DOI: 10.15766/mep_2374-8265.11313.Peer-Reviewed Original ResearchConceptsClinical Effort Against Secondhand Smoke ExposureNicotine replacement therapyAdult caregiversCeased trainingPrescription of nicotine replacement therapyChildren's exposure to secondhand smokePediatric residentsAdult caregivers of childrenExposure to secondhand smokeGroup of pediatric residentsCaregivers of childrenSmoking cessation skillsTrained pediatric providersNurse practitioner studentsSecondhand smoke exposureHealth professions studentsSmoking cessation techniquesFamily medicine residentsSurveys measuring changesSelf-perceived knowledgeTobacco cessation strategiesUrban academic centerPhysician championsState quitlinesPractitioner studentsReceipt of Smoking Cessation Medications Among People With and Without Human Immunodeficiency Virus in the Veterans Aging Cohort Study (2003–2018)
Shahrir S, Crothers K, McGinnis K, Chan K, Baeten J, Wilson S, Butt A, Pisani M, Baldassarri S, Justice A, Williams E. Receipt of Smoking Cessation Medications Among People With and Without Human Immunodeficiency Virus in the Veterans Aging Cohort Study (2003–2018). Open Forum Infectious Diseases 2023, 10: ofad089. PMID: 36968969, PMCID: PMC10034589, DOI: 10.1093/ofid/ofad089.Peer-Reviewed Original ResearchVeterans Aging Cohort StudyAging Cohort StudyHuman immunodeficiency virusCessation medicationsCohort studyCurrent smokersCurrent smokingHIV statusImmunodeficiency virusRelative riskHuman immunodeficiency virus statusSmoking cessation medicationsNicotine replacement therapyRates of receiptDangers of smokingOutpatient prescriptionsReplacement therapyPharmacy dataVirus statusTobacco useAnnual rateMedicationsSmokingPWHStatistical differenceCost-Effectiveness of Smoking Cessation Approaches in Emergency Departments
Miller T, Johnson M, Dziura J, Weiss J, Carpenter K, Grau L, Pantalon M, Abroms L, Collins L, Toll B, Bernstein S. Cost-Effectiveness of Smoking Cessation Approaches in Emergency Departments. American Journal Of Preventive Medicine 2023, 65: 39-44. PMID: 36710199, PMCID: PMC10293014, DOI: 10.1016/j.amepre.2023.01.006.Peer-Reviewed Original ResearchConceptsSmoking cessation interventionNicotine replacement therapyCessation interventionsReplacement therapyEmergency departmentMulticomponent smoking cessation interventionSmoking cessation approachesEmergency department visitsEffects of briefCessation approachesQuitline referralDepartment visitsTobacco treatmentDedicated staffIntervention componentsTobacco productsDistinct interventionsInterventionLow SESUnderstudied populationTherapyHigh rateIdeal timeParticipantsQuit
2022
Successful Optimization of Tobacco Dependence Treatment in the Emergency Department: A Randomized Controlled Trial Using the Multiphase Optimization Strategy
Bernstein S, Dziura J, Weiss J, Brooks A, Miller T, Vickerman K, Grau L, Pantalon M, Abroms L, Collins L, Toll B. Successful Optimization of Tobacco Dependence Treatment in the Emergency Department: A Randomized Controlled Trial Using the Multiphase Optimization Strategy. Annals Of Emergency Medicine 2022, 81: 209-221. PMID: 36585318, PMCID: PMC9868063, DOI: 10.1016/j.annemergmed.2022.08.018.Peer-Reviewed Original ResearchConceptsBrief Negotiation InterviewNicotine replacement therapyTobacco dependence treatmentEmergency departmentHospital emergency departmentReplacement therapyDependence treatmentMultiphase optimization strategyNicotine replacement therapy prescriptionTobacco dependence interventionsExhaled carbon monoxidePrimary endpointFirst doseControlled TrialsAbstinence ratesTelephone quitlinesClinical efficacyTherapy prescriptionTobacco abstinenceActive referralOdds ratioAdult smokersMulticomponent interventionPrimary analysisTherapySmoking Status, Nicotine Medication, Vaccination, and COVID-19 Hospital Outcomes: Findings from the COVID EHR Cohort at the University of Wisconsin (CEC-UW) Study
Piasecki T, Smith S, Baker T, Slutske W, Adsit R, Bolt D, Conner K, Bernstein S, Eng O, Lazuk D, Gonzalez A, Jorenby D, D’Angelo H, Kirsch J, Williams B, Nolan M, Hayes-Birchler T, Kent S, Kim H, Lubanski S, Yu M, Suk Y, Cai Y, Kashyap N, Mathew J, McMahan G, Rolland B, Tindle H, Warren G, An L, Boyd A, Brunzell D, Carrillo V, Chen L, Davis J, Deshmukh V, Dilip D, Ellerbeck E, Goldstein A, Iturrate E, Jose T, Khanna N, King A, Klass E, Mermelstein R, Tong E, Tsoh J, Wilson K, Theobald W, Fiore M. Smoking Status, Nicotine Medication, Vaccination, and COVID-19 Hospital Outcomes: Findings from the COVID EHR Cohort at the University of Wisconsin (CEC-UW) Study. Nicotine & Tobacco Research 2022, 25: 1184-1193. PMID: 36069915, PMCID: PMC9494410, DOI: 10.1093/ntr/ntac201.Peer-Reviewed Original ResearchConceptsNicotine replacement therapySARS-CoV-2 vaccinationCOVID-19 patientsCurrent smokersFormer smokersSmoking statusCOVID-19 outcomesICU admissionNRT prescriptionHospital outcomesVaccination statusReplacement therapySevere COVID-19 disease outcomesCOVID-19 clinical outcomesCOVID-19 disease outcomesBetter hospital outcomesOdds of deathBody mass indexElectronic health record dataLarge cohort studyCOVID-19 hospitalizationHealth record dataPotential beneficial effectsU.S. health systemEHR cohortClinical approach to the treatment of e-cigarette use among adolescents
Kaliamurthy S, Camenga DR. Clinical approach to the treatment of e-cigarette use among adolescents. Current Problems In Pediatric And Adolescent Health Care 2022, 52: 101203. PMID: 35534404, DOI: 10.1016/j.cppeds.2022.101203.Peer-Reviewed Educational MaterialsConceptsE-cigarette usePediatric healthcare providersHealthcare providersNicotine replacement therapyOff-label useSerious public health threatYears of ageE-cigarette cessationPublic health threatCessation strategiesReplacement therapyNicotine withdrawalClinical managementPediatric providersClinical approachAmerican AcademyBehavioral treatmentHealth consequencesHealth threatAdolescentsTreatmentProvidersFurther researchTherapySymptomsNicotine Patch Alters Patterns of Cigarette Smoking-Induced Dopamine Release: Patterns Relate to Biomarkers Associated With Treatment Response
Zakiniaeiz Y, Liu H, Gao H, Najafzadeh S, Ropchan J, Nabulsi N, Huang Y, Matuskey D, Chen MK, Cosgrove KP, Morris ED. Nicotine Patch Alters Patterns of Cigarette Smoking-Induced Dopamine Release: Patterns Relate to Biomarkers Associated With Treatment Response. Nicotine & Tobacco Research 2022, 24: 1597-1606. PMID: 35100429, PMCID: PMC9575980, DOI: 10.1093/ntr/ntac026.Peer-Reviewed Original ResearchConceptsNicotine replacement therapyDopamine releasePlacebo patchDorsal striatumTobacco smokingReplacement therapyFirst-line pharmacological treatmentVentral striatumMajor public health burdenPositron emission tomography scanEmission tomography scanPublic health burdenNicotine dependence levelNicotine metabolism rateNicotinic acetylcholine receptorsCounter-balanced orderTobacco smokersCigarette smokingSmoking cessationDopamine terminalsPharmacological treatmentDependent smokersFast metabolizersSlow metabolizersNicotine acts
2021
Pain and smoking study (PASS): A comparative effectiveness trial of smoking cessation counseling for veterans with chronic pain
Bastian LA, Driscoll M, DeRycke E, Edmond S, Mattocks K, Goulet J, Kerns RD, Lawless M, Quon C, Selander K, Snow J, Casares J, Lee M, Brandt C, Ditre J, Becker W. Pain and smoking study (PASS): A comparative effectiveness trial of smoking cessation counseling for veterans with chronic pain. Contemporary Clinical Trials Communications 2021, 23: 100839. PMID: 34485755, PMCID: PMC8391053, DOI: 10.1016/j.conctc.2021.100839.Peer-Reviewed Original ResearchCognitive-behavioral interventionsBehavioral interventionsAdaptive coping strategiesPain-related anxietyChronic painSmoking studiesGreater pain intensityCoping strategiesMotivational interviewingSmoking cessationPain-related functional interferenceTelephone counseling interventionCounseling interventionNicotine replacement therapyMental health comorbiditiesComparative effectiveness trialRandomized clinical trialsParticipantsEffectiveness trialRelapse managementVeteransCessation counselingBaseline characteristicsHealth comorbiditiesMedian agePreoperative contingency management intervention for smoking abstinence in cancer patients: trial protocol for a multisite randomised controlled trial
Rojewski AM, Fucito LM, Baker NL, Palmer AM, Foster MG, Warren GW, Bernstein SL, Toll BA. Preoperative contingency management intervention for smoking abstinence in cancer patients: trial protocol for a multisite randomised controlled trial. BMJ Open 2021, 11: e051226. PMID: 34187835, PMCID: PMC8245459, DOI: 10.1136/bmjopen-2021-051226.Peer-Reviewed Original ResearchConceptsSmoking abstinenceSelf-reported smoking abstinenceCancer-specific mortalityNicotine replacement therapyTime of surgeryDay of surgerySmoking cessation treatmentCancer treatment toxicitiesSouth Carolina Institutional Review BoardEffect of CMBreath carbon monoxideContingency management interventionCO breath testInstitutional review boardSubstantial health risksOperable cancerContinued smokingPeer-reviewed journalsPreoperative periodStandard careSurgical complicationsTreatment toxicitySecondary malignanciesCessation treatmentReplacement therapy
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