2025
Nicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective
Ameral V, Sofuoglu M, Kelly M. Nicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective. Expert Review Of Clinical Pharmacology 2025, 18: 189-196. PMID: 40047379, PMCID: PMC11961306, DOI: 10.1080/17512433.2025.2472837.Peer-Reviewed Original ResearchSmoking cessationE-cigarettesEvidence-based clinical guidelinesEfficacy of e-cigarettesBenefits of e-cigarettesSmoking cessation treatmentHarm reduction optionsHarm reduction principlesNicotine replacement therapyNicotine e-cigarettesQuality of lifeIncreased life expectancyNicotine useCessation treatmentClinical guidelinesNicotineSmokingLife expectancyCigarette smokingClinical pharmacology perspectivePharmacological perspectiveClinical practiceHigh riskLong-term effectsReplacement therapy
2024
Implications of Atrial Fibrillation for Guideline-Directed Therapy in Patients With Heart Failure JACC State-of-the-Art Review
Newman J, O'Meara E, Böhm M, Savarese G, Kelly P, Vardeny O, Allen L, Lancellotti P, Gottlieb S, Samad Z, Morris A, Desai N, Rosano G, Teerlink J, Giraldo C, Lindenfeld J. Implications of Atrial Fibrillation for Guideline-Directed Therapy in Patients With Heart Failure JACC State-of-the-Art Review. Journal Of The American College Of Cardiology 2024, 83: 932-950. PMID: 38418008, DOI: 10.1016/j.jacc.2023.12.033.Peer-Reviewed Original ResearchConceptsGuideline-directed medical therapyAtrial fibrillationHeart failureAssociated with significant morbiditySpectrum of ejection fractionPrevention of AFIncidence of AFGuideline-directed therapyDiagnosis of AFEjection fractionSignificant morbidityMedical therapyJACC State-of-the-Art ReviewPatientsFrequent hospitalizationsIncreased life expectancyAssociated with greater symptom burdenCardiovascular conditionsGreater symptom burdenTherapySymptom burdenLife expectancyFibrillationHeartPrognosisLongitudinal trends in causes of death among adults with HIV on antiretroviral therapy in Europe and North America from 1996 to 2020: a collaboration of cohort studies
Trickey A, McGinnis K, Gill M, Abgrall S, Berenguer J, Wyen C, Hessamfar M, Reiss P, Kusejko K, Silverberg M, Imaz A, Teira R, d'Arminio Monforte A, Zangerle R, Guest J, Papastamopoulos V, Crane H, Sterling T, Grabar S, Ingle S, Sterne J. Longitudinal trends in causes of death among adults with HIV on antiretroviral therapy in Europe and North America from 1996 to 2020: a collaboration of cohort studies. The Lancet HIV 2024, 11: e176-e185. PMID: 38280393, PMCID: PMC11656032, DOI: 10.1016/s2352-3018(23)00272-2.Peer-Reviewed Original ResearchConceptsCause-specific mortalityAvailability of effective antiretroviral therapyAll-Cause MortalityRates of all-cause mortalityPatterns of cause-specific mortalityCause-specific mortality ratesCohort studyAdjusted mortality rate ratiosAntiretroviral Therapy Cohort CollaborationMortality rate ratiosInternational Classification of DiseasesMortality rateLongitudinal trendsAccident-related mortalityRates of cause-specific mortalityProportion of deathsClassification of diseasesAIDS-related mortalityAIDS-related deathsAntiretroviral therapyInvestigate longitudinal trendsIncreased life expectancyInjection drug useHIV ageObservational cohort study
2022
Overcoming Therapy Resistance in Colon Cancer by Drug Repurposing
Zarif T, Yibirin M, De Oliveira-Gomes D, Machaalani M, Nawfal R, Bittar G, Bahmad H, Bitar N. Overcoming Therapy Resistance in Colon Cancer by Drug Repurposing. Cancers 2022, 14: 2105. PMID: 35565237, PMCID: PMC9099737, DOI: 10.3390/cancers14092105.Peer-Reviewed Original ResearchColorectal cancerDecreases chemotherapy toxicityTreatment of colorectal cancerOvercome therapy resistanceDevelopment of promising therapiesRates of obesityMetastatic settingChemotherapy toxicityStandard screening methodTherapy resistanceAnti-diabetic agentsAdjuvant roleColon cancerSurvival rateAnti-malarialsPromising therapiesDrug repurposingIncreased life expectancyPoor dietCancerGeneral populationAnti-hypertensiveDrugAnti-inflammatoryComorbidities
2020
Emergency General Surgery in the Elderly
Con J, Gogna S, Latifi R. Emergency General Surgery in the Elderly. 2020, 205-210. DOI: 10.1007/978-3-030-47963-3_15.Peer-Reviewed Original Research
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