2025
Correlates of Loneliness in Parkinson Disease During the COVID-19 Pandemic: A Longitudinal Study
de Figueiredo J, Kohn R, Patel A, Parsons E, Louis E, Koo B. Correlates of Loneliness in Parkinson Disease During the COVID-19 Pandemic: A Longitudinal Study. Behavioral Sciences 2025, 15: 1233. PMID: 41009263, PMCID: PMC12466522, DOI: 10.3390/bs15091233.Peer-Reviewed Original ResearchCorrelates of lonelinessEmotional supportHealth-related quality of lifeCOVID-19 pandemicLongitudinal studyAssociated with lonelinessParkinson's diseaseQuality of lifeEffects of lonelinessConsecutive PD outpatientsPublic health emergencyLinear regression analysisPD outpatientsPsychological variablesSocial isolationCOVID-19LonelinessHealth emergencyPD patientsRegression analysisTreatment planningDemoralizationExploring perceived and enacted stigma with related factors among gay, bisexual, and other men who have sex with men in Nepal
Sujan M, Khati A, Paudel K, Gautam K, Pandey A, Sharma S, Dhakal M, Wickersham J, Shrestha R. Exploring perceived and enacted stigma with related factors among gay, bisexual, and other men who have sex with men in Nepal. Sexual Health 2025, 22 PMID: 40977232, DOI: 10.1071/sh25031.Peer-Reviewed Original ResearchConceptsEnacted stigmaPatient Health Questionnaire-9Stigma reduction initiativesCross-sectional studyMultivariate linear regression analysisSleep Quality ScaleStigma ScalePerceived stigmaBackground StigmaExploratory factor analysisComprehensive interventionDepressive symptomsGBMSMStigmaAnal sexLinear regression analysisGroup sexOlder individualsSexual behaviorAssociated FactorsTransactional sexWell-beingReduction initiativesParticipantsQuality scalePain, fatigue, and associated gene expressions over chemotherapy in patients with colorectal cancer
Wu W, Li A, Singh V, Salner A, Chen M, Judge M, Cong X, Xu W. Pain, fatigue, and associated gene expressions over chemotherapy in patients with colorectal cancer. PLOS ONE 2025, 20: e0325849. PMID: 40577278, PMCID: PMC12204541, DOI: 10.1371/journal.pone.0325849.Peer-Reviewed Original ResearchConceptsSelf-report outcome measuresPain interferenceColorectal cancerOutcome measures of painHigher pain interferenceMixed-effects linear regression analysisMeasures of painStatistically significant associationSymptom burdenNon-HispanicProspective longitudinal studyFatigue patternsLinear mixed modelsFatigue levelsEffective interventionsTargeted interventionsLinear regression analysisSignificant associationCancer CenterPost-chemotherapyLongitudinal studyPainStage III cancerChemotherapy cyclesRegression analysisGrowth‐Associated Protein 43 Levels in the Cerebrospinal Fluid Correspond to the Cerebral Blood Flow Alterations in Alzheimer's Dementia Continuum: An Original Study
Songhori N, Goushky M, Khaleghi M, Mojerloo M, Sadeghi M, Mozafar M, Aghdam Z, Ghajar M, Kianifar Y, Karimzadeh F, Khosravi F, Mayeli M. Growth‐Associated Protein 43 Levels in the Cerebrospinal Fluid Correspond to the Cerebral Blood Flow Alterations in Alzheimer's Dementia Continuum: An Original Study. Health Science Reports 2025, 8: e70534. PMID: 40078900, PMCID: PMC11896815, DOI: 10.1002/hsr2.70534.Peer-Reviewed Original ResearchMild cognitive impairmentComposite scoreAlzheimer's Disease Neuroimaging InitiativeMini Mental State ExaminationExecutive function composite scoreMental State ExaminationCognitive impairmentIndependent t-testDiagnostic groupsDementia continuumMultiple linear regression analysisState ExaminationAlzheimer's diseaseAPOE-e4Cognitive statusLinear regression analysisCognitive composite scoreComparison of continuous variablesCognitive scoresConfounding factorsCN individualsCerebrospinal fluid biomarkersSignificant positive correlationCognitive functionMann-Whitney testPerceived Discrimination, Trauma, Mental Health, and Blood Pressure Outcomes Among Young African American/Black Mothers in the InterGEN Study.
Nyembwe A, Zhao Y, Millender E, Hall K, Caceres B, Taylor B, Morrison M, Prescott L, Potts-Thompson S, Aziz A, Aruleba F, Crusto C, Taylor J. Perceived Discrimination, Trauma, Mental Health, and Blood Pressure Outcomes Among Young African American/Black Mothers in the InterGEN Study. The Journal Of Cardiovascular Nursing 2025 PMID: 40052829, DOI: 10.1097/jcn.0000000000001190.Peer-Reviewed Original ResearchDepressive symptomsSecondary data analysis of dataAssociation of discriminationPresentation of depressive symptomsFactors associated with BPLongitudinal cohort studySecondary data analysisAssociated with blood pressureBlood pressure outcomesExperiences of discriminationInfluence of discriminationChildren aged 3InterGEN StudyMother-child dyadsPsychosocial measuresAA womenBlood pressureMental healthPressure outcomesCohort studyLinear regression analysisCulturally sensitive screening toolsScreening toolMaternal BPSensitive screening toolHIV risk perception and problematic alcohol use among urban slum residents in Bangladesh: findings from a cross-sectional survey
Sujan S, Sikder T, Siddique A, Hossain J, Hossen I, Saikat E, Uddin M, Keya S, Paudel K, Gautam K, Ha T, Shrestha R. HIV risk perception and problematic alcohol use among urban slum residents in Bangladesh: findings from a cross-sectional survey. AIDS Care 2025, 37: 1076-1084. PMID: 40043190, PMCID: PMC12213132, DOI: 10.1080/09540121.2025.2473941.Peer-Reviewed Original ResearchHIV risk perceptionUrban slum residentsProblematic alcohol useSexually transmitted infectionsAlcohol useSlum residentsHigh HIV risk perceptionRisk perceptionHistory of sexually transmitted infectionsPoor mental healthUrban slum settingsParticipants' mean ageCross-sectional surveyGlobal public health issueCross-sectional studyDecreased alcohol usePublic health issueMultivariate linear regression analysisHIV perceptionMental healthSlum settingsHIV epidemicHealth issuesUrban slumsLinear regression analysisBASELINE PROGNOSTIC FACTORS OF BOWEL URGENCY IMPROVEMENT IN PATIENTS WITH ULCERATIVE COLITIS TREATED WITH MIRIKIZUMAB
Dubinsky M, Schreiber S, Matsuoka K, Jairath V, Al-Bawardy B, Pellanda P, Zhu B, Bleakman A, Redondo I, Owen C, Limdi J. BASELINE PROGNOSTIC FACTORS OF BOWEL URGENCY IMPROVEMENT IN PATIENTS WITH ULCERATIVE COLITIS TREATED WITH MIRIKIZUMAB. Inflammatory Bowel Diseases 2025, 31: s62-s63. DOI: 10.1093/ibd/izae282.147.Peer-Reviewed Original ResearchNumerical rating scalePain numerical rating scaleModified Mayo scoreMultivariate linear regression analysisInflammatory Bowel Disease QuestionnaireUnivariate analysisUlcerative colitisMayo scorePrognostic variablesAnti-IL-23p19 antibodyBaseline characteristics of patientsAnti-IL-23p19Linear regression analysisPhase 3 trialRegression analysisCharacteristics of patientsUrgency Numeric Rating ScaleBristol Stool ScaleMultivariate regression analysisPost Hoc AnalysisUnivariate analysis of associationPrognostic factorsDisease extentBaseline characteristicsMirikizumab
2024
Identifying subgroups of individuals based on their epistemic stance, attachment dimensions and childhood trauma: A latent profile analysis
Delamain H, Saunders R, Tanzer M, Luyten P, Fonagy P, Campbell C. Identifying subgroups of individuals based on their epistemic stance, attachment dimensions and childhood trauma: A latent profile analysis. Journal Of Psychiatric Research 2024, 181: 701-708. PMID: 39753089, DOI: 10.1016/j.jpsychires.2024.12.033.Peer-Reviewed Original ResearchConceptsLatent profile analysisAttachment dimensionsChildhood traumaSubgroups of individualsMental health symptom severityWellbeing measuresRisk of mental health concernsMental health outcomesMental health concernsMental health symptomsRisk of negative outcomesHealth outcomesFour-profile solutionMental healthHealth symptomsSociodemographic variablesGroup comparison testsEducation levelHigher risk of negative outcomesLinear regression analysisGeneral populationRelationship statusDemographic factorsHealth concernEpistemic stanceThe Most Socially Vulnerable Patients Benefit the Most Following Gender Affirming Facial Surgery
Parikh N, Hu K, Ihnat J, Allam O, Diatta F, Rancu A, Wood S, Flores-Pérez P, Persing J, Alperovich M. The Most Socially Vulnerable Patients Benefit the Most Following Gender Affirming Facial Surgery. Journal Of Craniofacial Surgery 2024, 36: 772-776. PMID: 39637358, DOI: 10.1097/scs.0000000000010718.Peer-Reviewed Original ResearchArea deprivation index scoreDeprivation index scoreSocial vulnerability index scoresSocial Vulnerability IndexMinor themesImpact of social vulnerabilityNeighborhood socioeconomic disadvantageIndex scorePatient-reported outcomesAppearance satisfactionSocioeconomic disadvantageHome addressFACE-Q modulesSocial vulnerabilityVulnerable patientsLinear regression analysisImpact of surgeryUnivariate linear regression analysisPatient benefitThemesGeo-codedLack of informationRegression analysisScoresTransportation themeThe fetal origins of metabolic health: exploring the association between newborn biological age and metabolism hormones in childhood
Jia Z, Qiu F, He Y, Chen H, Yang C, Liu H, Zheng T, Xu S, Wang S, Li Y. The fetal origins of metabolic health: exploring the association between newborn biological age and metabolism hormones in childhood. BMC Medicine 2024, 22: 429. PMID: 39379967, PMCID: PMC11462715, DOI: 10.1186/s12916-024-03629-z.Peer-Reviewed Original ResearchConceptsRestricted cubic splinesLeptin levelsMetabolic hormonesMetabolic healthDNA methylationRestricted cubic spline analysisProspective birth cohort studyDNA methylation ageMother-child pairsBirth cohort studyDNA copy numberFetal originMitochondrial DNA copy numberResultsThe linear regression analysisReal-time PCRCohort studyHorvath's epigenetic clockInsulin levelsInverse associationLeptinQuantitative real-time PCRInfinium MethylationEPIC BeadChipElectrochemiluminescence assayLinear regression analysisMetabolic statusThe Associating Factors of Parent-Teen and Peer Relationships Among Chinese Adolescents with Type 1 Diabetes Mellitus
Luo J, Li Q, Whittemore R, Välimäki M, Guo J. The Associating Factors of Parent-Teen and Peer Relationships Among Chinese Adolescents with Type 1 Diabetes Mellitus. Psychology Research And Behavior Management 2024, 17: 3611-3623. PMID: 39435368, PMCID: PMC11492902, DOI: 10.2147/prbm.s474339.Peer-Reviewed Original ResearchDiabetes Self-ManagementPositive coping styleNegative coping styleSelf-ManagementCoping stylesParenting teensRelationships subscaleDevelopment of targeted interventionsAssociated FactorsType 1 diabetes mellitusMultivariate linear regression analysisRandomized Controlled TrialsPeer relationshipsPerceived stressDiabetes managementSelf-EfficacyLinear regression analysisBaseline dataPeer cohesionSocial demographicsYounger ageStyle trainingRegression analysisSubscalesAdolescentsAssociation Between Juvenile Psychotic Experiences and Problematic Gaming
Fernandes A, Biokino R, Miguel A, Machado V, Koga G, Fonseca L, Pan P, Roza T, Salum G, Passos I, Rohde L, Miguel E, Ziebold C, Gadelha A. Association Between Juvenile Psychotic Experiences and Problematic Gaming. Schizophrenia Bulletin Open 2024, 5: sgae021. PMID: 39296676, PMCID: PMC11408271, DOI: 10.1093/schizbullopen/sgae021.Peer-Reviewed Original ResearchPsychotic experiencesProblematic gamingGame addictionDSM-IVBrazilian community sampleDSM-IV diagnosisMental health conditionsCommunity samplePsychiatric disordersCross-sectional subsamplePsychiatric conditionsAssociated with significant adverse outcomesReport PEBehavioral pathwaysLevels of PESignificant adverse outcomesAssociated with PEPE scoresSociodemographic variablesAdverse outcomesBrazilian cohortDisordersParticipantsHealth conditionsLinear regression analysisThe European psychiatric association (EPA) – early career psychiatrists committee survey on trainees’ and early-career psychiatrists’ attitudes towards therapeutic drug monitoring (TDM) use and utility during antipsychotic treatment
Schoretsanitis G, Correll C, Agorastos A, Sanchez A, Erzin G, Grigoras R, Benussi M, Gondek T, Guloksuz S, Højlund M, Jerotic S, Kilic O, Metaj E, Sidhu D, Skandali N, Skuhareuski A, Tveito M, Wolthusen R, Communication and Publications E, Chumakov E, de Filippis R. The European psychiatric association (EPA) – early career psychiatrists committee survey on trainees’ and early-career psychiatrists’ attitudes towards therapeutic drug monitoring (TDM) use and utility during antipsychotic treatment. The World Journal Of Biological Psychiatry 2024, 25: 342-351. PMID: 38905131, DOI: 10.1080/15622975.2024.2367138.Peer-Reviewed Original ResearchConceptsEuropean Psychiatric AssociationAntipsychotic treatmentPsychiatrists' attitudesTherapeutic drug monitoringEarly-career psychiatristsExploratory factor analysisBenefit of therapeutic drug monitoringPsychiatric AssociationAntipsychoticsNegative expectationsAssociated with frequencyTDM useDrug monitoringTherapeutic drug monitoring useFactor analysisBeliefs of patientsHigh-income countriesLow-/middle-income countriesResponse varianceClinical benefitClozapineOutpatient settingLinear regression analysisClinical settingPsychiatristsThe Impact of a Pandemic on a Military Oral and Maxillofacial Pathology Biopsy Service
Miller T, Dickens N, Rehmel M, Jones B, Hamlin N, Robbins Q. The Impact of a Pandemic on a Military Oral and Maxillofacial Pathology Biopsy Service. Military Medicine 2024, 189: e1797-e1804. PMID: 38536204, DOI: 10.1093/milmed/usae102.Peer-Reviewed Original ResearchMaxillofacial pathology biopsy serviceBiopsy diagnosisBiopsy serviceHuman papillomavirus (HPV)-associated squamous cell carcinomaSquamous cell carcinomaStudent's t-testMalignant biopsiesCell carcinomaBiopsy RegistryBiopsy sitePatient demographicsPre-malignantPatient biopsiesDental schoolsIn-officeBiopsyDentist appointmentsFollow-on carePercentage of diagnosesCoronavirus disease 2019Linear regression analysisChi-square analysisDiagnosisAnalysis of casesPatientsSex differences in the pleiotropy of hearing difficulty with imaging-derived phenotypes: a brain-wide investigation
He J, Cabrera-Mendoza B, De Angelis F, Pathak G, Koller D, Curhan S, Curhan G, Mecca A, van Dyck C, Polimanti R. Sex differences in the pleiotropy of hearing difficulty with imaging-derived phenotypes: a brain-wide investigation. Brain 2024, 147: 3395-3408. PMID: 38454550, PMCID: PMC11449129, DOI: 10.1093/brain/awae077.Peer-Reviewed Original ResearchImaging-derived phenotypesHearing difficultiesBrain imaging-derived phenotypesSex-combined analysisLatent causal variable analysesMendelian randomization approachGeneralized linear regression analysisLocal genetic correlation analysisMultivariate generalized linear regression analysisGenome-wide association studiesLatent causal variableGenetic correlation analysisGenetic correlationsLocal genetic correlationMendelian randomizationPeripheral auditory systemOlder adultsGWAS dataLinear regression analysisHealth burdenGenomic regionsAssociation studiesPleiotropic regionsSex differencesTranscriptome regulationTaste and smell function in Wilson's disease
Salmon M, Cohen W, Hu F, Aydin A, Coskun A, Schilsky M, Doty R. Taste and smell function in Wilson's disease. Journal Of The Neurological Sciences 2024, 459: 122949. PMID: 38493734, DOI: 10.1016/j.jns.2024.122949.Peer-Reviewed Original ResearchWilson's diseaseSmell functionUniversity of Pennsylvania Smell Identification TestPennsylvania Smell Identification TestSmell test scoresSmell Identification TestAbnormal copper metabolismOlfactory dysfunctionWD patientsOlfactory functionNeurological symptomsControl subjectsPrimary medicationTaste functionPathophysiological mechanismsHealthy controlsLinear regression analysisMultiple linear regression analysisIdentification TestCopper metabolismPatientsNO effectTaste testRegression analysisDiseaseVisit duration of office-based ophthalmology visits in a nationally representative sample
DeBroff B, Andoh J. Visit duration of office-based ophthalmology visits in a nationally representative sample. Advances In Ophthalmology & Visual System 2024, 14: 18-23. DOI: 10.15406/aovs.2024.14.00456.Peer-Reviewed Original ResearchNational Ambulatory Medical Care SurveyOphthalmology visitsVisit durationElectronic medical record useMedical record useProvider-patient encountersHealthcare utilization patternsOffice-based visitsNon-metropolitan locationsPatient statusLow-resource populationsNationally Representative SampleShortage of ophthalmologistsMean visit durationPrimary outcome measureRecord useCare SurveyChronic conditionsHealth informationInternational ClassificationMetropolitan statusMedicaid insuranceInsurance typeOutcome measuresLinear regression analysisStructural Basis for p19 Targeting by Anti–IL-23 Biologics: Correlations with Short- and Long-Term Efficacy in Psoriasis
Daniele S, Eldirany S, Damiani G, Ho M, Bunick C. Structural Basis for p19 Targeting by Anti–IL-23 Biologics: Correlations with Short- and Long-Term Efficacy in Psoriasis. JID Innovations 2024, 4: 100261. PMID: 38445231, PMCID: PMC10914523, DOI: 10.1016/j.xjidi.2024.100261.Peer-Reviewed Original ResearchIL-23Clinical efficacyIL-23 inhibitors risankizumabSurface areaLong-term clinical efficacyMolecular propertiesIL-23 inhibitorsSolvent accessible surface areaHydrogen-deuterium exchangeIL-23 p19 subunitAccessible surface areaAssociated with short-Clinical efficacy scorePlaque psoriasisClinical responseP19 subunitCrystallographic experimentsPsoriasis pathogenesisReceptor epitopesInhibitor epitopesPsoriasisLinear regression analysisEfficacyTherapeutic classesBinding affinitySmooth versus Textured Tissue Expanders: Comparison of Outcomes and Complications in 536 Implants
Allam O, Dinis J, Almeida M, Junn A, Mozaffari M, Shah R, Chong L, Olawoyin O, Mehta S, Park K, Avraham T, Alperovich M. Smooth versus Textured Tissue Expanders: Comparison of Outcomes and Complications in 536 Implants. Archives Of Plastic Surgery 2024, 51: 042-051. PMID: 38425846, PMCID: PMC10901592, DOI: 10.1055/s-0043-1775592.Peer-Reviewed Original ResearchTextured tissue expandersPain scoresTissue expanderTwo-stage breast reconstructionTextured surface implantsExpander fill volumeStudy evaluated outcomesAssociated with ageComparison of outcomesRegression analysisBilateral reconstructionPrepectoral placementComplication rateTextured implantsNo significant differenceBreast reconstructionPerioperative informationSurface implantsOperative timeTE exchangeComplicationsLinear regression analysisSignificant differencePainChi-square
2023
Mass spectrometry on cerebrospinal fluid uncovers association of novel glycolysis biomarkers with Alzheimer’s disease in a complex clinical cohort
de Geus M, Leslie S, Wang W, Lam T, Broekman M, Neefjes S, Nairn A, Carlyle B, Arnold S. Mass spectrometry on cerebrospinal fluid uncovers association of novel glycolysis biomarkers with Alzheimer’s disease in a complex clinical cohort. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.078466.Peer-Reviewed Original ResearchAlzheimer's diseaseMild cognitive impairmentHospital neurology serviceNon-AD diagnosesDiagnostic lumbar puncturePrognosis of ADCerebrospinal fluid biomarkersClinic cohortFurther mechanistic studiesNeurology serviceFDG-PETBrain metabolismFluid biomarkersLumbar puncturePatient cohortClinical indicationsDisease progressionATN biomarkersClinical cohortTreatment responseComplex cohortBackground DiagnosisCSF samplesTreatment efficacyLinear regression analysis
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