2023
Association of Somatic ATP2A2 Damaging Variants With Grover Disease
Seli D, Ellis K, Goldust M, Shah K, Hu R, Zhou J, McNiff J, Choate K. Association of Somatic ATP2A2 Damaging Variants With Grover Disease. JAMA Dermatology 2023, 159: 745-749. PMID: 37195706, PMCID: PMC10193258, DOI: 10.1001/jamadermatol.2023.1139.Peer-Reviewed Original ResearchConceptsGrover's diseaseGD tissuesSomatic single nucleotide variantsControl tissuesRetrospective case seriesCase series studyAnnotation-dependent depletion scoreConsecutive patientsCase seriesKidney failureHistopathologic findingsAcantholytic disordersOrgan transplantationMAIN OUTCOMEBiopsy tissueSeries studyDarier's diseaseClinical diagnosisParticipant's DNAOlder individualsTissue DNADiseaseDisordersPatientsBiopsy
2020
Determining the significance of psammoma bodies in pelvic washings: A 10‐year retrospective review
Sun T, Pitman MB, Torous VF. Determining the significance of psammoma bodies in pelvic washings: A 10‐year retrospective review. Cancer Cytopathology 2020, 129: 83-89. PMID: 32931128, DOI: 10.1002/cncy.22346.Peer-Reviewed Original ResearchConceptsPelvic washing specimensBorderline tumorsPsammoma bodiesPelvic washingsSerous adenocarcinomaWashing specimensLow-grade serous adenocarcinomaHigh-grade serous adenocarcinomaSerous borderline tumorsEndometrioid endometrial carcinomaBenign processSurgical pathology specimensBorderline diseaseOccult diseaseYounger patientsRetrospective reviewEndometrial carcinomaGynecologic surgeryUncommon findingHistopathologic findingsClinical significanceCytologic analysisRetrospective searchMesothelial hyperplasiaPathology specimensPerniosis during the COVID‐19 pandemic: Negative anti‐SARS‐CoV‐2 immunohistochemistry in six patients and comparison to perniosis before the emergence of SARS‐CoV‐2
Ko CJ, Harigopal M, Damsky W, Gehlhausen JR, Bosenberg M, Patrignelli R, McNiff JM. Perniosis during the COVID‐19 pandemic: Negative anti‐SARS‐CoV‐2 immunohistochemistry in six patients and comparison to perniosis before the emergence of SARS‐CoV‐2. Journal Of Cutaneous Pathology 2020, 47: 997-1002. PMID: 32745281, PMCID: PMC7436569, DOI: 10.1111/cup.13830.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 nucleocapsid proteinPerivascular lymphocytesImmunohistochemical stainingCOVID-19 pandemicSARS-CoV-2 immunohistochemistryNucleocapsid proteinSARS-CoV-2Inflammatory lesionsHistopathologic findingsIntravascular occlusionMicroscopic findingsPerniosisIntravascular materialLymphocytesLesionsPatientsStainingPandemicSuch casesCuffingHistopathologyCasesImmunohistochemistryFindingsProteinCutaneous Involvement by Mantle Cell Lymphoma: Expanding the Spectrum of Histopathologic Findings in a Series of 9 Cases.
Panse G, Cowper S, Ko CJ, Subtil A. Cutaneous Involvement by Mantle Cell Lymphoma: Expanding the Spectrum of Histopathologic Findings in a Series of 9 Cases. American Journal Of Dermatopathology 2020, 42: 848-853. PMID: 32675465, DOI: 10.1097/dad.0000000000001742.Peer-Reviewed Case Reports and Technical NotesConceptsMantle cell lymphomaCutaneous involvementCell lymphomaSystemic mantle cell lymphomaAggressive B-cell neoplasmSingle institutional seriesSame biopsy specimenSite of involvementMarginal zone lymphomaB-cell neoplasmsImmunoglobulin M expressionSurface IgM expressionInstitutional seriesSecond malignanciesSystemic involvementClinicopathologic featuresCutaneous lesionsSitu hybridization studiesBiopsy specimenHistopathologic findingsMetastatic melanomaFirst manifestationDirect immunofluorescenceHematolymphoid neoplasmsTissue manifestationsClinical Characteristics, Histopathology, and Tissue Immunolocalization of Chikungunya Virus Antigen in Fatal Cases
Sharp T, Keating M, Shieh W, Bhatnagar J, Bollweg B, Levine R, Blau D, Torres J, Rivera A, Perez-Padilla J, Munoz-Jordan J, Sanabria D, Fischer M, Garcia B, Tomashek K, Zaki S. Clinical Characteristics, Histopathology, and Tissue Immunolocalization of Chikungunya Virus Antigen in Fatal Cases. Clinical Infectious Diseases 2020, 73: e345-e354. PMID: 32615591, PMCID: PMC11307670, DOI: 10.1093/cid/ciaa837.Peer-Reviewed Original ResearchConceptsSeptic shockFatal casesTissue specimensMononuclear cellsSplenic follicular dendritic cellsChikungunya virus antigenIntra-alveolar hemorrhageFatal septic shockFollicular dendritic cellsChikungunya virus infectionCommon histopathologic findingsBlood mononuclear cellsReverse transcriptase-polymerase chain reactionTranscriptase-polymerase chain reactionCHIKV antigenSevere comorbiditiesAcute illnessClinical characteristicsCHIKV infectionDendritic cellsMedian ageRecord reviewIllness onsetImmunohistochemical findingsHistopathologic findingsEffect of High Fructose Corn Sirup on Pancreatic Ductal Adenocarcinoma Induced by Dimethyl Benzantracene (DMBA) in Rats
Ozcan-Sınır G, Inan S, Suna S, Tamer CE, Akgül MB, Bagdas D, Sonmez G, Evrensel T, Kaya E, Sarandol E, Dündar HZ, Tarım OF, Ercan I, Sıgırlı D, Incedayı B, Copur OU. Effect of High Fructose Corn Sirup on Pancreatic Ductal Adenocarcinoma Induced by Dimethyl Benzantracene (DMBA) in Rats. Nutrition And Cancer 2020, 73: 339-349. PMID: 32475178, DOI: 10.1080/01635581.2020.1770811.Peer-Reviewed Original ResearchConceptsPancreatic ductal adenocarcinomaMale Sprague-Dawley ratsDevelopment of PDACSprague-Dawley ratsConsumption of sugarHistopathologic findingsPancreatic cancerDawley ratsDuctal adenocarcinomaRat modelGlucose levelsChow consumptionBody weightHistologic specimensDifferentiated typeDimethyl benzanthraceneDaily intakeRatsEntire groupTissue processing protocolChowTumor formationSignificant differencesFeeding periodGroupContribution of Sonoelastography to Diagnosis in Distinguishing Benign and Malignant Breast Masses
Yıldız M, Goya C, Adin M. Contribution of Sonoelastography to Diagnosis in Distinguishing Benign and Malignant Breast Masses. Journal Of Ultrasound In Medicine 2020, 39: 1395-1403. PMID: 32083349, DOI: 10.1002/jum.15236.Peer-Reviewed Original ResearchConceptsB-mode ultrasoundStrain indexMalignant lesionsBenign lesionsSonoelastographic examinationBreast massesMean strain indexDiagnostic performanceMean strain index valueSubcutaneous adipose tissueStrain index valueFemale patientsMean ageHistopathologic evaluationHistopathologic findingsScoring methodDifferential diagnosisAdipose tissueDistinguishing BenignUnnecessary biopsiesDiagnostic efficacyLesionsSolid breast massesMalignant breast massesDiagnostic accuracy
2019
Hypergranulotic dyscornification: 30 cases of a striking epithelial reaction pattern
Roy SF, Ko CJ, Moeckel GW, Mcniff JM. Hypergranulotic dyscornification: 30 cases of a striking epithelial reaction pattern. Journal Of Cutaneous Pathology 2019, 46: 742-747. PMID: 31157457, DOI: 10.1111/cup.13522.Peer-Reviewed Original ResearchConceptsBenign keratosesDistinctive histopathologic findingsHistological reaction patternEpidermolytic hyperkeratosisReaction patternsBowen's diseaseRetrospective reviewMean ageProminent granular layerHistopathologic findingsEpidermoid cystKeratin immunohistochemistryClinical impressionSeborrheic keratosisPositive stainingNeck areaAbnormal keratinizationKeratohyaline granulesUnique reaction patternReproducible findingsKeratosesCytoplasmic areaGranular layerHyperkeratosisPrevious reportsImmune Checkpoint Inhibitor–Associated Pericarditis
Altan M, Toki MI, Gettinger SN, Carvajal-Hausdorf DE, Zugazagoitia J, Sinard JH, Herbst RS, Rimm DL. Immune Checkpoint Inhibitor–Associated Pericarditis. Journal Of Thoracic Oncology 2019, 14: 1102-1108. PMID: 30851443, PMCID: PMC6617516, DOI: 10.1016/j.jtho.2019.02.026.Peer-Reviewed Original ResearchConceptsAdverse eventsCTLA-4 inhibitorsImmune checkpoint inhibitorsDeath-1/Pericardial window procedureCheckpoint inhibitorsThird patientClinical presentationCardiac toxicityHistopathologic findingsSide effectsPericarditisPatientsDeath ligandsPotential mechanismsWindow procedureInhibitorsImmunotherapyNSCLCCardiotoxicityAutopsiesTherapy
2017
Squamous proliferations on the legs of women: Qualitative examination of histopathology, TP53 sequencing, and implications for diagnosis in a series of 30 cases
Ko CJ, Glusac EJ, McNiff JM, Rodic N, Leffell DJ. Squamous proliferations on the legs of women: Qualitative examination of histopathology, TP53 sequencing, and implications for diagnosis in a series of 30 cases. Journal Of The American Academy Of Dermatology 2017, 77: 1126-1132.e1. PMID: 28709693, DOI: 10.1016/j.jaad.2017.04.1119.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaProminent cytologic atypiaMultiple squamous cell carcinomasCytologic atypiaSquamous proliferationTP53 mutationsDetectable TP53 mutationsLegs of womenFollicle-like structuresCell carcinomaHistopathologic findingsMultiple lesionsSCC lesionsHistopathologic analysisTP53 sequencingNumerous tumorsSmall seriesTP53 variantsClinical phenotypeKeratoacanthomaLesionsTumorsDifferent patientsAtypiaReactive phenomenon
2016
Anterior Chamber Non-Hodgkin Lymphoma of the Iris Masquerading as Uveitis-Glaucoma-Hyphema Syndrome
Gauthier AC, Nguyen A, Munday WR, Xu ML, Materin MA. Anterior Chamber Non-Hodgkin Lymphoma of the Iris Masquerading as Uveitis-Glaucoma-Hyphema Syndrome. Ocular Oncology And Pathology 2016, 2: 230-233. PMID: 27843901, PMCID: PMC5091236, DOI: 10.1159/000445119.Peer-Reviewed Original Research
2015
White fibrous papulosis of the neck.
Schaffer P, Tran K, Kaplan J, Patel R, Kamino H, Ramachandran S, Franks A. White fibrous papulosis of the neck. Dermatology Online Journal 2015, 20 PMID: 25526334, DOI: 10.5070/d32012025054.Peer-Reviewed Original Research
2013
Histopathologic Manifestations of Drug-induced Hepatotoxicity
Zhang X, Ouyang J, Thung SN. Histopathologic Manifestations of Drug-induced Hepatotoxicity. Clinics In Liver Disease 2013, 17: 547-564. PMID: 24099017, DOI: 10.1016/j.cld.2013.07.004.Peer-Reviewed Original ResearchConceptsDrug-induced hepatotoxicityChronic liver diseaseLiver diseaseCareful medication historySpecific histopathologic patternAbnormal liver testsLiver testsResponsible drugSymptom onsetLiver injuryMedication historyCounter medicationsHistopathologic patternHistopathologic findingsDrug exposureHistopathologic manifestationsHepatobiliary diseaseCertain drugsSupplementary agentPrescription drugsHepatotoxicityHerbal productsLatent periodDiseaseDrugsPediatric Cholestatic Disorders Approach to Pathologic Diagnosis
Morotti RA, Jain D. Pediatric Cholestatic Disorders Approach to Pathologic Diagnosis. Surgical Pathology Clinics 2013, 6: 205-225. PMID: 26838972, DOI: 10.1016/j.path.2013.03.001.Peer-Reviewed Original ResearchLiver diseaseDiagnostic challengePediatric cholestatic disordersClinical featuresPediatric groupHistopathologic featuresCholestatic disordersHistopathologic findingsPathologic diagnosisDifferential diagnosisDiagnostic modalitiesBile synthesisMolecular abnormalitiesDiagnosisDiseaseDisordersSignificant overlapPathophysiologyMolecular geneticsAbnormalities
2007
Intrathoracic xanthoma mimicking lung cancer in a patient with familial hypercholesterolemia type II: a case report.
Guvener M, Ucar H, Tok M, Dogan O, Yildiz I, Yilmaz M, Firat P. Intrathoracic xanthoma mimicking lung cancer in a patient with familial hypercholesterolemia type II: a case report. The Heart Surgery Forum 2007, 10: e3-5. PMID: 17162397, DOI: 10.1532/hsf98.20061030.Peer-Reviewed Original ResearchConceptsLarge tumor-like massChest X-ray filmComplaints of dyspneaBenign soft tissue lesionTumor-like massSoft tissue lesionsX-ray filmsChest painCardiopulmonary bypassRight hemithoraxPrior diagnosisCase reportHistopathologic findingsLung cancerTendon sheathTomography scanTracheal segmentsThoracic cavityRare locationFamilial hypercholesterolemiaXanthomasPatientsType IIDyspneaCough
2006
The Association Between Marijuana Smoking and Lung Cancer: A Systematic Review
Mehra R, Moore BA, Crothers K, Tetrault J, Fiellin DA. The Association Between Marijuana Smoking and Lung Cancer: A Systematic Review. JAMA Internal Medicine 2006, 166: 1359-1367. PMID: 16832000, DOI: 10.1001/archinte.166.13.1359.Peer-Reviewed Original ResearchConceptsLung cancerMarijuana smokingLung cancer risk factorsCancer risk factorsPotential adverse health outcomesPersons 18 yearsAdverse health outcomesFurther rigorous studiesEnglish-language studiesLung changesTobacco smokingTobacco smokersHistopathologic abnormalitiesHistopathologic findingsEmbase databasesPremalignant changesRisk factorsObservational studyMarijuana exposureMethodologic deficienciesTobacco useNineteen studiesSmokingTar exposureLack of adjustment
2004
A Case of Adenomyosis per se with a Uterine Weight of 475 g
Harmanli O, Shen T, Zhu S, Chatwani A. A Case of Adenomyosis per se with a Uterine Weight of 475 g. Gynecologic And Obstetric Investigation 2004, 58: 216-218. PMID: 15331854, DOI: 10.1159/000080360.Peer-Reviewed Original ResearchConceptsPelvic reconstructive surgerySignificant uterine enlargementCases of adenomyosisPelvic organ prolapseUterine weightVaginal hysterectomyUterine enlargementHistopathologic findingsLarge uterusOrgan prolapseReconstructive surgeryAdenomyosisUterusExtreme enlargementEnlargementHysterectomyProlapseSurgeryWomen
2001
Nephrogenic Fibrosing Dermopathy
Cowper S, Su L, Bhawan J, Robin H, LeBoit P. Nephrogenic Fibrosing Dermopathy. American Journal Of Dermatopathology 2001, 23: 383-393. PMID: 11801769, DOI: 10.1097/00000372-200110000-00001.Peer-Reviewed Original ResearchConceptsNephrogenic fibrosing dermopathyElastic fibersPositive dermal dendrocytesCollagen bundlesDifferent kidney diseasesThick collagen bundlesRenal transplantCutaneous changesDendritic cellsFibrosing disorderRenal diseaseSystemic findingsIndurated plaquesDermal mucinKidney diseaseSingle institutionDermal dendrocytesDialysis centersHistopathologic examinationHistopathologic findingsRenal dialysisEntire dermisSpindle cellsEarly lesionsRoutine microscopy
1996
Refractory epilepsy: comparison of MR imaging, CT, and histopathologic findings in 117 patients.
Bronen RA, Fulbright RK, Spencer DD, Spencer SS, Kim JH, Lange RC, Sutilla C. Refractory epilepsy: comparison of MR imaging, CT, and histopathologic findings in 117 patients. Radiology 1996, 201: 97-105. PMID: 8816528, DOI: 10.1148/radiology.201.1.8816528.Peer-Reviewed Original Research
1995
Histologic findings in acute HIV exanthem
Goldman G, Milstone L, Shapiro P. Histologic findings in acute HIV exanthem. Journal Of Cutaneous Pathology 1995, 22: 371-373. PMID: 7499579, DOI: 10.1111/j.1600-0560.1995.tb01422.x.Peer-Reviewed Case Reports and Technical Notes
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