2024
A nested case‐control study of untargeted plasma metabolomics and lung cancer among never‐smoking women within the prospective Shanghai Women's Health Study
Rahman M, Shu X, Jones D, Hu W, Ji B, Blechter B, Wong J, Cai Q, Yang G, Gao Y, Zheng W, Rothman N, Walker D, Lan Q. A nested case‐control study of untargeted plasma metabolomics and lung cancer among never‐smoking women within the prospective Shanghai Women's Health Study. International Journal Of Cancer 2024, 155: 508-518. PMID: 38651675, PMCID: PMC11284831, DOI: 10.1002/ijc.34929.Peer-Reviewed Original ResearchShanghai Women's Health StudyProspective Shanghai Women's Health StudyNested Case-Control StudyNever-smoking womenLung cancerWomen's Health StudyCase-control studyNever-smokersPlasma metabolomeLung adenocarcinomaRisk factorsPre-diagnostic plasmaHealth StudyLung cancer risk factorsMetabolic featuresCancer risk factorsCancer-free womenAssociated with lung adenocarcinomaFactors of lung cancerLung cancer pathogenesisRisk factors of lung cancerLung cancer casesConditional logistic regression modelsEtiology of lung cancerTraffic-related air pollution
2023
Polygenic Risk Score, Environmental Tobacco Smoke, and Risk of Lung Adenocarcinoma in Never-Smoking Women in Taiwan
Blechter B, Chien L, Chen T, Chang I, Choudhury P, Hsiao C, Shu X, Wong J, Chen K, Chang G, Tsai Y, Su W, Huang M, Chen Y, Chen C, Hung H, Hu J, Shi J, Zheng W, Rositch A, Chen C, Chatterjee N, Yang P, Rothman N, Hsiung C, Lan Q. Polygenic Risk Score, Environmental Tobacco Smoke, and Risk of Lung Adenocarcinoma in Never-Smoking Women in Taiwan. JAMA Network Open 2023, 6: e2339254. PMID: 37955902, PMCID: PMC10644212, DOI: 10.1001/jamanetworkopen.2023.39254.Peer-Reviewed Original ResearchConceptsEnvironmental tobacco smokeAbsolute riskLung adenocarcinomaPolygenic risk scoresETS exposureTobacco smokeRisk scoreLung cancer risk factorsLung cancer screening programsGenetic susceptibilityLung cancer incidence ratesLifetime absolute riskCancer screening programsCancer risk factorsCase-control studyCancer incidence ratesRelative risk estimatesOverall genetic susceptibilitySuper-additive interactionRecent genome-wide association studiesLung cancerIncidence rateRisk factorsScreening programMAIN OUTCOME
2018
Smoking Is the Most Significant Modifiable Lung Cancer Risk Factor in Systemic Lupus Erythematosus.
Bernatsky S, Ramsey-Goldman R, Petri M, Urowitz MB, Gladman DD, Fortin PR, Yelin EH, Ginzler E, Hanly JG, Peschken C, Gordon C, Nived O, Aranow C, Bae SC, Isenberg D, Rahman A, Hansen JE, Pierre Y, Clarke AE. Smoking Is the Most Significant Modifiable Lung Cancer Risk Factor in Systemic Lupus Erythematosus. The Journal Of Rheumatology 2018, 45: 393-396. PMID: 29335347, PMCID: PMC5834350, DOI: 10.3899/jrheum.170652.Peer-Reviewed Original ResearchConceptsLung cancer risk factorsSystemic lupus erythematosusCancer risk factorsLung cancer casesLung cancer riskLung cancerRisk factorsSLE cohortDisease activityLupus erythematosusDrug exposureCancer casesCancer riskMcGill University Health CentreCumulative disease activityIncident lung cancerUniversity Health CentreCancer risk studiesInstitutional review boardHigher SLEDAIMedication exposureSLE controlsAdjusted effectHealth centersAdjusted model
2006
The Association Between Marijuana Smoking and Lung Cancer: A Systematic Review
Mehra R, Moore BA, Crothers K, Tetrault J, Fiellin DA. The Association Between Marijuana Smoking and Lung Cancer: A Systematic Review. JAMA Internal Medicine 2006, 166: 1359-1367. PMID: 16832000, DOI: 10.1001/archinte.166.13.1359.Peer-Reviewed Original ResearchConceptsLung cancerMarijuana smokingLung cancer risk factorsCancer risk factorsPotential adverse health outcomesPersons 18 yearsAdverse health outcomesFurther rigorous studiesEnglish-language studiesLung changesTobacco smokingTobacco smokersHistopathologic abnormalitiesHistopathologic findingsEmbase databasesPremalignant changesRisk factorsObservational studyMarijuana exposureMethodologic deficienciesTobacco useNineteen studiesSmokingTar exposureLack of adjustment
2003
Fruits, vegetables and lung cancer: A pooled analysis of cohort studies
Smith‐Warner S, Spiegelman D, Yaun S, Albanes D, Beeson WL, van den Brandt PA, Feskanich D, Folsom AR, Fraser GE, Freudenheim JL, Giovannucci E, Goldbohm RA, Graham S, Kushi LH, Miller AB, Pietinen P, Rohan TE, Speizer FE, Willett WC, Hunter DJ. Fruits, vegetables and lung cancer: A pooled analysis of cohort studies. International Journal Of Cancer 2003, 107: 1001-1011. PMID: 14601062, DOI: 10.1002/ijc.11490.Peer-Reviewed Original ResearchConceptsLung cancer riskCancer riskVegetable consumptionLung cancerRelative riskLung cancer risk factorsStudy-specific relative risksIncident lung cancer casesTotal fruitCancer risk factorsLung cancer incidenceLung cancer casesTotal vegetable consumptionRandom-effects modelCohort studyCurrent smokersSmoking habitsProspective studyQuintiles 2Pooled analysisLowest quintileResidual confoundingInverse associationRisk factorsCancer incidence
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