2025
A Randomized Phase 3 Study Evaluating the Efficacy and Safety of Alogliptin in Pediatric Participants with Type 2 Diabetes Mellitus
Peng X, Klingensmith G, Hsia D, Xie Y, Czerniak R, Tamborlane W, Shah A. A Randomized Phase 3 Study Evaluating the Efficacy and Safety of Alogliptin in Pediatric Participants with Type 2 Diabetes Mellitus. Diabetes Therapy 2025, 16: 865-883. PMID: 40032809, PMCID: PMC12006607, DOI: 10.1007/s13300-025-01700-3.Peer-Reviewed Original ResearchType 2 diabetes mellitusAlogliptin treatmentEfficacy endpointPediatric patientsAntihyperglycemic therapyOral dipeptidyl peptidase-4 inhibitorHbA1c levelsRandomized phase 3 studyDipeptidyl peptidase-4 inhibitorsSafety of alogliptinPlacebo-controlled trialPhase 3 studyBaseline to weekPeptidase-4 inhibitorsBody mass indexImprove glycemic controlDouble-blindPlacebo groupSecondary endpointsBackground metforminSchedule APharmacological therapyMass indexGlycosylated hemoglobinInsulin therapy
2021
Associations between Fasting Duration, Timing of First and Last Meal, and Cardiometabolic Endpoints in the National Health and Nutrition Examination Survey
Wirth M, Zhao L, Turner-McGrievy G, Ortaglia A. Associations between Fasting Duration, Timing of First and Last Meal, and Cardiometabolic Endpoints in the National Health and Nutrition Examination Survey. Nutrients 2021, 13: 2686. PMID: 34444846, PMCID: PMC8397975, DOI: 10.3390/nu13082686.Peer-Reviewed Original ResearchConceptsNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyNighttime fasting durationNutrition Examination SurveyCardiometabolic endpointsExamination SurveyLow HDLAssociated with higher HbA1cFasting durationOne-hour increaseCross-sectional dataPublic health datasetsCardiometabolic benefitsHealth datasetsHigh-density lipoprotein (HDLC-reactive proteinSurvey design proceduresLow-density lipoprotein (LDLHigher HbA1cLogistic regressionLipoprotein (HDLLipoprotein (LDLHbA1c %Glycosylated hemoglobinLower LDL
2012
The T1D Exchange Clinic Registry
Beck RW, Tamborlane WV, Bergenstal RM, Miller KM, DuBose SN, Hall CA, Network F. The T1D Exchange Clinic Registry. The Journal Of Clinical Endocrinology & Metabolism 2012, 97: 4383-4389. PMID: 22996145, DOI: 10.1210/jc.2012-1561.Peer-Reviewed Original ResearchConceptsT1D Exchange Clinic RegistryClinic registryAutoimmune type 1 diabetesFirst-degree family membersClinic-based registrySevere hypoglycemic eventsChronic diabetic complicationsType 1 diabetesContinuous glucose monitoringAssessment of associationsDiabetes historyDiabetic ketoacidosisEndocrinology centersPatient characteristicsRenal diseaseChart extractionT1D ExchangeGlycosylated hemoglobinHypoglycemic eventsDiabetic complicationsRetinopathy treatmentGeneral healthFamily historyMedical conditionsRegistry
2010
Blood Pressure is Associated with BMI and Predicts Plasma Glucose Control and Triglycerides among Obese Latinos with Type 2 Diabetes
Chhabra J, Vega‐López S, D'Agostino D, Fernandes M, Segura‐Pérez S, Damio G, Pérez‐Escamilla R. Blood Pressure is Associated with BMI and Predicts Plasma Glucose Control and Triglycerides among Obese Latinos with Type 2 Diabetes. The FASEB Journal 2010, 24: 935.3-935.3. DOI: 10.1096/fasebj.24.1_supplement.935.3.Peer-Reviewed Original ResearchBlood pressureDiastolic BPPlasma glucoseDiagnosis of hypertensionSystolic blood pressurePlasma glucose controlRelationship of BMIMetabolic syndrome indicatorsType 2 diabetesObese LatinosHDL cholesterolObese populationGlucose controlGlycosylated hemoglobinLatino patientsBlood samplesBMIType 2TriglyceridesHealth disparitiesPatientsFPGDlDemographic informationLDLImportance of Measuring Glycosylated Hemoglobin in Patients With Myocardial Infarction and Known Diabetes Mellitus
Stolker JM, Sun D, Conaway DG, Jones PG, Masoudi FA, Peterson PN, Krumholz HM, Kosiborod M, Spertus JA. Importance of Measuring Glycosylated Hemoglobin in Patients With Myocardial Infarction and Known Diabetes Mellitus. The American Journal Of Cardiology 2010, 105: 1090-1094. PMID: 20381658, PMCID: PMC2856846, DOI: 10.1016/j.amjcard.2009.12.010.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionDiabetes mellitusMyocardial infarctionChronic glycemic controlPoor controlMyocardial infarction patientsProspective registryGlycemic controlClinical outcomesGlycosylated hemoglobinHemoglobin assessmentInfarction patientsAMI careDM controlDM treatmentHospital levelPatientsDisease managementAdditional quality indicatorsMarked variabilityMellitusInfarctionCurrent performance measuresDM evaluationAssessment
1998
Glycosylated Hemoglobin in Insulin-Dependent Diabetes Mellitus Related to Preeclampsia
Hsu C, Hong S, Nickless N, Copel J. Glycosylated Hemoglobin in Insulin-Dependent Diabetes Mellitus Related to Preeclampsia. American Journal Of Perinatology 1998, 15: 199-202. PMID: 9572378, DOI: 10.1055/s-2007-993926.Peer-Reviewed Original ResearchConceptsIDDM pregnant womenMean HbA1c valuesIncidence of preeclampsiaHbA1c valuesPregnant womenGestational periodExact testInsulin-dependent diabetes mellitusHigher mean HbA1cPathogenesis of preeclampsiaWeeks of gestationFisher's exact testDifferent gestational periodsNormal mean valueIDDM pregnanciesMean HbA1cDiabetes mellitusWeeks' gestationGlycosylated hemoglobinInsulin-DependentRetrospective studyTrophoblastic invasionMedical recordsPreeclampsiaHigh incidence
1992
Effect of growth hormone treatment on hyperinsulinemia associated with turner syndrome
Caprio S, Boulware S, Press M, Sherwin R, Rubin K, Carpenter T, Plewe G, Tamborlane W. Effect of growth hormone treatment on hyperinsulinemia associated with turner syndrome. The Journal Of Pediatrics 1992, 120: 238-243. PMID: 1735819, DOI: 10.1016/s0022-3476(05)80434-2.Peer-Reviewed Original ResearchConceptsControl subjectsGrowth hormoneTurner syndromeHyperinsulinemic responseInsulin responseHyperglycemic glucose clamp techniqueSecond-phase insulin responseInsulin-stimulated glucose metabolismGlucose-stimulated insulin responseMonths of therapyMonths of treatmentTotal cholesterol levelsExcessive insulin secretionGrowth hormone treatmentGlucose clamp techniqueGlucose clamp procedureHuman growth hormoneBlood pressureGlucose incrementGlycosylated hemoglobinInsulin resistancePlasma levelsCholesterol levelsClamp procedureHealthy children
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