2025
Effect of empiric antibiotics against Pseudomonas aeruginosa on mortality in hospitalized patients: a systematic review and meta-analysis—authors’ response
Hunter C, Marhoffer E, Holleck J, Alshaeba S, Grimshaw A, Chou A, Carey G, Gunderson C. Effect of empiric antibiotics against Pseudomonas aeruginosa on mortality in hospitalized patients: a systematic review and meta-analysis—authors’ response. Journal Of Antimicrobial Chemotherapy 2025, 80: 1162-1162. PMID: 39976564, DOI: 10.1093/jac/dkaf047.Peer-Reviewed Original Research
2024
Effect of empiric antibiotics against Pseudomonas aeruginosa on mortality in hospitalized patients: a systematic review and meta-analysis
Hunter C, Marhoffer E, Holleck J, Alshaeba S, Grimshaw A, Chou A, Carey G, Gunderson C. Effect of empiric antibiotics against Pseudomonas aeruginosa on mortality in hospitalized patients: a systematic review and meta-analysis. Journal Of Antimicrobial Chemotherapy 2024, 80: 322-333. PMID: 39656468, DOI: 10.1093/jac/dkae422.Peer-Reviewed Original ResearchPrevalence of P. aeruginosaEffects of empiric antibioticsEmpirical antibioticsUrinary tract infectionSoft tissue infectionsCommunity-acquired pneumoniaTract infectionsTissue infectionsP. aeruginosaMortality benefitHospitalized patientsPseudomonas aeruginosaPooled adjusted ORP. aeruginosa infectionType of infectionStudy of patientsAbsolute mortality benefitIntensive care settingSystematic literature searchNosocomial pneumoniaSeptic shockMeaningful benefitAdjusted ORWeb of ScienceCompare mortality ratesFever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document
Nohra E, Appelbaum R, Farrell M, Carver T, Jung H, Kirsch J, Kodadek L, Mandell S, Nassar A, Pathak A, Paul J, Robinson B, Cuschieri J, Stein D. Fever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document. Trauma Surgery & Acute Care Open 2024, 9: e001303. PMID: 38835635, PMCID: PMC11149120, DOI: 10.1136/tsaco-2023-001303.Peer-Reviewed Original ResearchAmerican Association for the SurgeryIntensive care unitClinical consensus documentCatheter-associated urinary infectionDuration of antibiotic treatmentCatheter-related bloodstream infectionNecrotizing soft tissue infectionConsensus documentWorkup of feverIntra-abdominal infectionsSurgical intensive care unitSoft tissue infectionsEvaluation of feverSurgical site infectionVentilator-associated pneumoniaDiagnosis of infectionSurgical intensive careEmpirical antibioticsBloodstream infectionsRespiratory specimensUrinary infectionTissue infectionsSite infectionAntibiotic treatmentTreat infections
2023
Estimated mortality with early empirical antibiotic coverage of methicillin-resistant Staphylococcus aureus in hospitalized patients with bacterial infections: a systematic review and meta-analysis
Carey G, Holleck J, Alshaeba S, Jayakrishnan R, Gordon K, Grimshaw A, Gunderson C. Estimated mortality with early empirical antibiotic coverage of methicillin-resistant Staphylococcus aureus in hospitalized patients with bacterial infections: a systematic review and meta-analysis. Journal Of Antimicrobial Chemotherapy 2023, 78: 1150-1159. PMID: 36964648, DOI: 10.1093/jac/dkad078.Peer-Reviewed Original ResearchConceptsCommon infectious syndromesEmpirical antibioticsPrevalence of MRSAInfectious syndromesMRSA infectionIll patientsMortality rateSystematic reviewAbsolute mortality benefitAnti-MRSA therapyEmpirical antibiotic coverageLow-risk infectionsSoft tissue infectionsUrinary tract infectionAbsolute risk reductionMethicillin-resistant Staphylococcus aureusCatheter-related infectionsStudy of patientsBaseline mortality ratesSystematic literature searchWeb of ScienceMRSA coverageAntibiotic coverageEmpirical antimicrobialsMortality benefit
2020
T-cell and NK-cell lymphomas in the lung
Pan Z, Xu ML. T-cell and NK-cell lymphomas in the lung. Seminars In Diagnostic Pathology 2020, 37: 273-282. PMID: 32448591, DOI: 10.1053/j.semdp.2020.04.003.Peer-Reviewed Original ResearchConceptsT-cell lymphomaWorld Health Organization classificationNK-cell lymphomasAdequate antibiotic therapyTypical radiologic featuresPrinciples of treatmentDifferent histologic typesPrecise pathologic diagnosisHilar adenopathyEmpirical antibioticsSystemic lymphomaWedge biopsyAntibiotic therapyLymphomas accountRadiologic featuresRadiologic findingsBronchoscopic examinationHistologic typePleural effusionClinical symptomsRecurrent infectionsCystic changesOrganization classificationPathologic diagnosisPulmonary opacities
1987
Prolongation of survival for high-grade malignant gliomas with adjuvant high-dose BCNU and autologous bone marrow transplantation.
Johnson D, Thompson J, Corwin J, Mosley K, Smith M, de los Reyes R, Daly M, Petty A, Lamaster D, Pierson W. Prolongation of survival for high-grade malignant gliomas with adjuvant high-dose BCNU and autologous bone marrow transplantation. Journal Of Clinical Oncology 1987, 5: 783-9. PMID: 3553437, DOI: 10.1200/jco.1987.5.5.783.Peer-Reviewed Original ResearchConceptsAutologous bone marrow transplantationHigh-dose BCNUBone marrow transplantationSignificant survival advantageMarrow transplantationMedian survivalMalignant gliomasBone marrowSurvival advantageConsecutive historical control patientsDied of pulmonary hemorrhageWeeks of initial surgeryHigh-grade malignant gliomasBone marrow infusionProlongation of survivalPoor performance statusAbsolute granulocyte countHistorical control patientsAutologous bone marrowMalignant glial tumorsHistorical control groupEmpirical antibioticsBrain irradiationInitial surgeryMarrow infusion
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