2025
1145 Higher Proceduralist Stroke Thrombectomy Volume is Associated With Reduced Inpatient Mortality
Koo A, Renedo D, Ney J, Amllay A, Kanzler M, Stogniy S, Alawieh A, Sujijantarat N, Antonios J, Al Kasab S, Malhotra A, Hebert R, Matouk C, de Havenon A. 1145 Higher Proceduralist Stroke Thrombectomy Volume is Associated With Reduced Inpatient Mortality. Neurosurgery 2025, 71: 177-178. DOI: 10.1227/neu.0000000000003360_1145.Peer-Reviewed Original ResearchCut-pointsAbsolute risk of deathAssociated with lower oddsState Inpatient DatabasesFlorida State Inpatient DatabaseIn-hospital moralityRates of in-hospital mortalityPrimary study outcomeCare certificationRisk of deathOptimal cut-pointAssociated with reduced inpatient mortalityThrombectomy-capable stroke centersOverall careRetrospective cohort studyAIS patientsIn-Hospital DeathLow-volume cohortLower oddsIn-Hospital MortalityPotential confoundersAbsolute riskVolume cohortsInpatient mortalityCohort study
2024
Higher proceduralist stroke thrombectomy volume is associated with reduced inpatient mortality
Koo A, Renedo D, Ney J, Amllay A, Kanzler M, Stogniy S, Alawieh A, Sujijantarat N, Antonios J, Al Kasab S, Malhotra A, Hebert R, Matouk C, de Havenon A. Higher proceduralist stroke thrombectomy volume is associated with reduced inpatient mortality. Journal Of NeuroInterventional Surgery 2024, jnis-2024-022021. PMID: 39214687, DOI: 10.1136/jnis-2024-022021.Peer-Reviewed Original ResearchIn-Hospital DeathIn-Hospital MortalityAcute ischemic strokeCut-pointsAbsolute risk of deathAssociated with lower oddsState Inpatient DatabasesFlorida State Inpatient DatabaseIn-hospital moralityRates of in-hospital mortalityDiagnosis of acute ischemic strokePrimary study outcomeRisk of deathStroke careOptimal cut-pointAssociated with reduced inpatient mortalityEndovascular thrombectomyRetrospective cohort studyLower oddsPotential confoundersAbsolute riskAcute ischemic stroke patientsInpatient mortalityCohort studyInpatient Database
2023
The interaction between geriatric and neighborhood vulnerability: Delineating prehospital risk among older adult emergency general surgery patients
Zogg C, Falvey J, Kodadek L, Staudenmayer K, Davis K. The interaction between geriatric and neighborhood vulnerability: Delineating prehospital risk among older adult emergency general surgery patients. Journal Of Trauma And Acute Care Surgery 2023, 96: 400-408. PMID: 37962136, PMCID: PMC10922165, DOI: 10.1097/ta.0000000000004191.Peer-Reviewed Original ResearchGeriatric vulnerabilitiesOlder adultsEGS careAdverse outcomesHospital Frailty Risk ScoreEmergency general surgery patientsGreater riskFlorida State Inpatient DatabaseFrailty Risk ScoreGeneral surgery patientsState Inpatient DatabasesArea Deprivation IndexEthnic minority patientsNeighborhood vulnerabilityEGS outcomesHazard ratioOlder patientsSurgery patientsPatient ageEGS conditionsInpatient DatabaseVulnerable patientsPatient residesMinority patientsRisk scoreDemographic Disparities in the Incidence, Clinical Characteristics, and Outcome of Posterior Reversible Encephalopathy Syndrome in the United States
Otite F, Patel S, Anikpezie N, Hoffman H, Beutler T, Akano E, Aneni E, Lamikanra O, Osondu C, Wee C, Burke D, Albright K, Latorre J, Mejico L, Khandelwal P, Chaturvedi S. Demographic Disparities in the Incidence, Clinical Characteristics, and Outcome of Posterior Reversible Encephalopathy Syndrome in the United States. Neurology 2023, 101: e1554-e1559. PMID: 37487751, PMCID: PMC10585693, DOI: 10.1212/wnl.0000000000207604.Peer-Reviewed Original ResearchConceptsPosterior reversible encephalopathy syndromeNational Readmission DatabaseReversible encephalopathy syndromeEncephalopathy syndromeFemale patientsHispanic patientsMale patientsSex-standardized incidenceRetrospective cohort studyRace-specific incidenceSimilar demographic distributionState Inpatient DatabasesNon-Hispanic whitesIncident hospitalizationClinical characteristicsCohort studyFirst hospitalizationBlack patientsInpatient DatabasePatientsNew casesIncidenceStudy periodDemographic disparitiesHospitalizationAssociation Between Hospital-Documented Atrial Fibrillation and Central Retinal Artery Occlusion
Lusk J, Song A, Unnithan S, Al-Khalidi H, Delic A, de Havenon A, Biousse V, Schrag M, Poli S, Piccini J, Xian Y, O’Brien E, Mac Grory B. Association Between Hospital-Documented Atrial Fibrillation and Central Retinal Artery Occlusion. Stroke 2023, 54: 983-991. PMID: 36729390, PMCID: PMC11173326, DOI: 10.1161/strokeaha.122.042292.Peer-Reviewed Original ResearchConceptsCentral retinal artery occlusionRetinal artery occlusionCardiovascular comorbiditiesArtery occlusionAtrial fibrillationInverse associationNon-Hispanic white race/ethnicityState Emergency Department DatabasesWhite race/ethnicityPrespecified sensitivity analysisPrimary end pointRisk of strokeCause-specific hazards modelEmergency Department DatabasesEmergency department settingPrimary risk factorState Inpatient DatabasesPositive control outcomesRace/ethnicityMedian followCohort studyCumulative incidenceIschemic strokeAF statusInpatient Database
2022
Safety Warning about Laparoscopic Power Morcellation in Hysterectomy: A Cost-Effectiveness Analysis of National Impact
Xu X, Desai VB, Schwartz PE, Gross CP, Lin H, Schymura MJ, Wright JD. Safety Warning about Laparoscopic Power Morcellation in Hysterectomy: A Cost-Effectiveness Analysis of National Impact. Women's Health Reports 2022, 3: 369-384. PMID: 35415718, PMCID: PMC8994439, DOI: 10.1089/whr.2021.0101.Peer-Reviewed Original Research
2021
Morbidity and Mortality Trends of Pancreatitis: An Observational Study
Ingraham NE, King S, Proper J, Siegel L, Zolfaghari EJ, Murray TA, Vakayil V, Sheka A, Feng R, Guzman G, Roy SS, Muddappa D, Usher MG, Chipman JG, Tignanelli CJ, Pendleton KM. Morbidity and Mortality Trends of Pancreatitis: An Observational Study. Surgical Infections 2021, 22: 1021-1030. PMID: 34129395, PMCID: PMC8851213, DOI: 10.1089/sur.2020.473.Peer-Reviewed Original ResearchConceptsState Inpatient DatabasesAcute pancreatitisGallbladder diseaseHealthcare costsMortality rateUtilization Project State Inpatient DatabasesIncidence of pancreatitisInpatient mortality rateCrude mortality rateHospital-based databaseLarge hospital-based databaseHospital-level dataHospital mortalityInpatient mortalityPatient demographicsMedian ageInpatient DatabaseMedian lengthEndoscopic interventionAdmission yearDecreased oddsObservational studyPancreatitisSurgical providersMedical providers
2020
Hospital variation in responses to safety warnings about power morcellation in hysterectomy
Xu X, Desai VB, Wright JD, Lin H, Schwartz PE, Gross CP. Hospital variation in responses to safety warnings about power morcellation in hysterectomy. American Journal Of Obstetrics And Gynecology 2020, 224: 589.e1-589.e13. PMID: 33359176, PMCID: PMC8180513, DOI: 10.1016/j.ajog.2020.12.1207.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overFemaleGuideline AdherenceHealthcare DisparitiesHospitalsHumansHysterectomyIntraoperative ComplicationsLaparoscopyLogistic ModelsMiddle AgedMorcellationOutcome Assessment, Health CarePatient SafetyPostoperative ComplicationsPractice Guidelines as TopicPractice Patterns, Physicians'Retrospective StudiesRisk AssessmentUnited StatesYoung AdultConceptsLaparoscopic supracervical hysterectomyOpen abdominal hysterectomySupracervical hysterectomyPower morcellationAbdominal hysterectomySurgical complicationsMajor complicationsPatient clinical risk factorsNew York Statewide PlanningClinical risk factorsDistinct trajectory patternsState Ambulatory SurgeryState Inpatient DatabasesSafety warningsTrajectory groupsResearch Cooperative SystemLow useHigher useHysterectomy practiceMinor complicationsBenign hysterectomyBenign indicationsComplication riskHospital variationCorpus uteriRisk of Ischemic Stroke in Patients With Atrial Fibrillation After Extracranial Hemorrhage
Zhou E, Lord A, Boehme A, Henninger N, de Havenon A, Vahidy F, Ishida K, Torres J, Mistry EA, Mac Grory B, Sheth KN, Gurol ME, Furie K, Elkind MSV, Yaghi S. Risk of Ischemic Stroke in Patients With Atrial Fibrillation After Extracranial Hemorrhage. Stroke 2020, 51: 3592-3599. PMID: 33028172, PMCID: PMC7751804, DOI: 10.1161/strokeaha.120.029959.Peer-Reviewed Original ResearchConceptsExtracranial hemorrhageIschemic strokeAtrial fibrillationAnticoagulation therapyGenitourinary cancersSubgroup analysisCalifornia State Inpatient DatabaseFuture ischemic strokePrimary admission diagnosisAcute ischemic strokeAtrial appendage closureHistory of strokeCox regression modelState Inpatient DatabasesSeverity/typeVASc scoreAdmission diagnosisHemorrhagic complicationsSubsequent hospitalizationAppendage closureHazard ratioHospital admissionInpatient DatabasePertinent demographicPrevious diagnosisGeographic Variation in the Utilization of and Mortality After Emergency General Surgery Operations in the Northeastern and Southeastern United States
Becher RD, Jin L, Warren JL, Gill TM, DeWane MP, Davis KA, Zhang Y. Geographic Variation in the Utilization of and Mortality After Emergency General Surgery Operations in the Northeastern and Southeastern United States. Annals Of Surgery 2020, 275: 340-347. PMID: 32516232, PMCID: PMC7726051, DOI: 10.1097/sla.0000000000003939.Peer-Reviewed Original ResearchConceptsHospital service areasSubsequent mortalityEmergency general surgery careEmergency general surgery operationsEGS operationsCommon EGS operationsAge-standardized ratesGeneral surgery careState Inpatient DatabasesGeneral surgery operationsRandom-effects modelWide geographic variationHospital mortalityInpatient DatabaseSurgery careKruskal-Wallis testMortality rateUnwarranted variationMortalityStandardized ratesLinear random effects modelSurgery operationsUnited StatesGeographic variationCareHospital Variation in Geriatric Surgical Safety for Emergency Operation
Becher RD, Sukumar N, DeWane MP, Stolar MJ, Gill TM, Schuster KM, Maung AA, Zogg CK, Davis KA. Hospital Variation in Geriatric Surgical Safety for Emergency Operation. Journal Of The American College Of Surgeons 2020, 230: 966-973.e10. PMID: 32032720, PMCID: PMC7409563, DOI: 10.1016/j.jamcollsurg.2019.10.018.Peer-Reviewed Original ResearchConceptsStandardized mortality ratioHospital-level characteristicsGeneral surgery operationsGeriatric patientsEmergency operationHospital variationEmergency general surgery operationsMean standardized mortality ratioCalifornia State Inpatient DatabaseHospital-based mortalitySignificant hospital variationPatients 65 yearsSubstantial excess mortalitySurgery operationsState Inpatient DatabasesMixed effects logistic regression modelsCommon general surgery operationsLow-mortality outliersLogistic regression modelsPostoperative mortalityHospital deathOlder patientsInpatient DatabaseMortality outcomesNonelective operations
2019
High-performance acute care hospitals: Excelling across multiple emergency general surgery operations in the geriatric patient.
DeWane MP, Sukumar N, Stolar MJ, Gill TM, Maung AA, Schuster KM, Davis KA, Becher RD. High-performance acute care hospitals: Excelling across multiple emergency general surgery operations in the geriatric patient. Journal Of Trauma And Acute Care Surgery 2019, 87: 140-146. PMID: 31259872, PMCID: PMC7656193, DOI: 10.1097/ta.0000000000002273.Peer-Reviewed Original ResearchConceptsCommon EGS operationsEmergency general surgeryOlder patientsGeriatric patientsEmergency general surgery operationsEGS operationsCalifornia State Inpatient DatabaseGeneral surgery hospitalsPatients 65 yearsRisk-adjusted mortalitySurvival rates 1State Inpatient DatabasesGeneral surgery operationsClusters of hospitalsOperation typeHospital performanceEGS patientsSurgery HospitalInpatient DatabaseGroup of hospitalsGeriatric populationGeneral surgeryPatientsHospitalLevel IIITop-tier emergency general surgery hospitals: Good at one operation, good at them all.
DeWane MP, Sukumar N, Stolar MJ, Gill TM, Maung AA, Schuster KM, Davis KA, Becher RD. Top-tier emergency general surgery hospitals: Good at one operation, good at them all. Journal Of Trauma And Acute Care Surgery 2019, 87: 289-296. PMID: 31349347, PMCID: PMC6771423, DOI: 10.1097/ta.0000000000002367.Peer-Reviewed Original ResearchConceptsRisk-adjusted mortalityEGS hospitalsHospital risk-adjusted mortalityOperation typeEGS operationsCalifornia State Inpatient DatabaseGeneral surgery hospitalsHospital-level factorsAcute care hospitalsState Inpatient DatabasesAmerican Hospital Association databasePoor-performing hospitalsSystems of careLow-risk operationAssessment of mortalityAdult patientsCare hospitalSurgery HospitalInpatient DatabaseHospital characteristicsMultinomial logistic regressionMortality rateHospitalLevel IIIZ-scoreHospital Operative Volume and Quality Indication for General Surgery Operations Performed Emergently in Geriatric Patients
Becher RD, DeWane MP, Sukumar N, Stolar MJ, Gill TM, Becher RM, Maung AA, Schuster KM, Davis KA. Hospital Operative Volume and Quality Indication for General Surgery Operations Performed Emergently in Geriatric Patients. Journal Of The American College Of Surgeons 2019, 228: 910-923. PMID: 31005629, PMCID: PMC6582986, DOI: 10.1016/j.jamcollsurg.2019.02.053.Peer-Reviewed Original ResearchConceptsHospital operative volumeGeneral surgery operationsGeriatric patientsOperative volumeEmergency operationHospital volumeProbability of survivalEmergency general surgery operationsCalifornia State Inpatient DatabaseRetrospective cohort studySurgery operationsState Inpatient DatabasesHigher operative volumesAverage mortality riskOlder patientsCohort studyInpatient DatabaseGeriatric populationSurgical careSurgical qualityAmerican CollegeMortality riskOptimizing outcomesStandardized increasePatientsEvaluating mortality outlier hospitals to improve the quality of care in emergency general surgery.
Becher RD, DeWane MP, Sukumar N, Stolar MJ, Gill TM, Maung AA, Schuster KM, Davis KA. Evaluating mortality outlier hospitals to improve the quality of care in emergency general surgery. Journal Of Trauma And Acute Care Surgery 2019, 87: 297-306. PMID: 30908450, PMCID: PMC6660354, DOI: 10.1097/ta.0000000000002271.Peer-Reviewed Original ResearchConceptsStandardized mortality ratioOutlier hospitalsHospital variationMortality ratioStandardized mortalityEmergency general surgery operationsCalifornia State Inpatient DatabaseEGS operationsCommon EGS operationsSignificant hospital variationEmergency general surgeryHospital-level characteristicsHospital-level variablesSignificant excess mortalityGeneral surgery operationsState Inpatient DatabasesQuality improvement initiativesQuality of careHospital quality indicatorsNational Quality ForumEGS outcomesInpatient DatabaseExcess mortalityOnly hospitalEpidemiologic studies
2017
Current Healthcare Utilization Patterns and Most Common Reasons for Admission Amongst Patients with Sickle Cell Disease
Calhoun C, Keller M, Olsen M, King A. Current Healthcare Utilization Patterns and Most Common Reasons for Admission Amongst Patients with Sickle Cell Disease. Blood 2017, 130: 866. DOI: 10.1182/blood.v130.suppl_1.866.866.Peer-Reviewed Original ResearchSickle cell diseaseVaso-occlusive crisisSCD patientsState Inpatient DatabasesIndex hospitalizationRespiratory infectionsHealthcare utilizationSCD populationAge groupsAdult careCell diseaseCommon reasonHuman Research Protection OfficeICD-9-CM diagnosis codesICD-9-CM diagnosisUtilization Project State Inpatient DatabasesYoung adult age groupPrimary insurance typeVaso-occlusive episodesAnnual healthcare costsChronic lung diseaseHealthcare utilization patternsHospital resource useYears age groupHigher mortality risk
2015
Standardized Data Collection Practices and the Racial/Ethnic Distribution of Hospitalized Patients
Chakkalakal RJ, Green JC, Krumholz HM, Nallamothu BK. Standardized Data Collection Practices and the Racial/Ethnic Distribution of Hospitalized Patients. Medical Care 2015, 53: 666-672. PMID: 26147864, PMCID: PMC4503513, DOI: 10.1097/mlr.0000000000000392.Peer-Reviewed Original ResearchCosts, Effectiveness, and Workload Impact of Management Strategies for Women With an Adnexal Mass
Havrilesky L, Dinan M, Sfakianos G, Curtis L, Barnett J, Van Gorp T, Myers E. Costs, Effectiveness, and Workload Impact of Management Strategies for Women With an Adnexal Mass. Obstetrical & Gynecological Survey 2015, 70: 253-255. DOI: 10.1097/01.ogx.0000464937.42384.2d.Peer-Reviewed Original ResearchPostmenopausal womenAdnexal massesPremenopausal womenReferral algorithmCA 125Clinical outcomesReferral strategiesCost-effective strategyEnd Results-MedicareMarkov microsimulation modelState Inpatient DatabasesOptimal cost-effective strategyRelative survival dataGynecologists guidelinesBiomarker validation studiesInitial surgeryGynecologic oncologistsInpatient DatabaseMalignancy AlgorithmPremenopausalEffective referralCutoff valueMedical careEffectiveness studiesSubspecialistsThe Impact of Regionalization of Cystectomy on Racial Disparities in Bladder Cancer Care
Casey M, Gross T, Wisnivesky J, Stensland K, Oh W, Galsky M. The Impact of Regionalization of Cystectomy on Racial Disparities in Bladder Cancer Care. Journal Of Urology 2015, 194: 36-41. PMID: 25623748, DOI: 10.1016/j.juro.2015.01.076.Peer-Reviewed Original ResearchConceptsBladder cancer careLow-volume hospitalsRacial disparitiesCancer careBlack patientsVolume hospitalsNew York State Inpatient DatabaseQuality of careRegionalization of surgical careState Inpatient DatabasesBladder cancerHospital useBlack communityPatient communitySurgical careVulnerable subpopulationsHospital volumeInpatient DatabaseCareWhite raceBlack raceLogistic regressionPatients treated with cystectomyDisparitiesHigher likelihoodAssociation between Respiratory Syncytial Virus Activity and Pneumococcal Disease in Infants: A Time Series Analysis of US Hospitalization Data
Weinberger DM, Klugman KP, Steiner CA, Simonsen L, Viboud C. Association between Respiratory Syncytial Virus Activity and Pneumococcal Disease in Infants: A Time Series Analysis of US Hospitalization Data. PLOS Medicine 2015, 12: e1001776. PMID: 25562317, PMCID: PMC4285401, DOI: 10.1371/journal.pmed.1001776.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusPneumococcal pneumoniaRate of hospitalizationPneumococcal diseaseHospitalization dataSeven-valent pneumococcal conjugate vaccineBacterial infectionsRespiratory syncytial virus activityLaboratory-confirmed dataPneumococcal pneumonia hospitalizationsPneumococcal conjugate vaccineIntroduction of PCV7Secondary bacterial infectionState Inpatient DatabasesPoisson regression modelsRSV hospitalizationPCV7 introductionPneumonia hospitalizationsConjugate vaccineInpatient DatabaseSyncytial virusPneumococcal septicemiaPneumonia casesEpidemic timingHospitalization
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