2025
Disentangling informing participants from obtaining their consent
O'Rourke P, Ali J, Carrithers J, Magnus D, Wilfond B, Bull S, Dember L, D'Onofrio G, Goldman J, Ho P, Melnick E, Staman K, Tulsky J, Vazquez M, Volandes A, Wendler D. Disentangling informing participants from obtaining their consent. Learning Health Systems 2025 DOI: 10.1002/lrh2.70014.Peer-Reviewed Original ResearchResearch consentParticipants' understandingContext of routine careStudy team membersPragmatic clinical trialsContext of trialsRoutine careConsentWaiverParticipant consentParticipant engagementResearch participantsEthical analysisTeam membersSignificant riskInstitutional review boardParticipantsParticipants' abilityReview boardCommunicating informationTrialsRegulatory criteriaRisk
2024
Balancing act: the complex role of artificial intelligence in addressing burnout and healthcare workforce dynamics
Pavuluri S, Sangal R, Sather J, Taylor R. Balancing act: the complex role of artificial intelligence in addressing burnout and healthcare workforce dynamics. BMJ Health & Care Informatics 2024, 31: e101120. PMID: 39181545, PMCID: PMC11344516, DOI: 10.1136/bmjhci-2024-101120.Peer-Reviewed Original ResearchConceptsQuality of patient careSustainability of health systemsComplexity of medical informationArtificial intelligenceWorkforce attritionHealth systemClinical skillsPatient careSense of purposeHealthcare workersHealthcareMedical informationWorkforce dynamicsMedical practiceProfessional attributesDigital scribeData management systemCognitive burdenBurnoutAdvanced data management systemsAI technologyAI potentialAutomated billingSignificant riskCaregivers
2023
Bronchoscopy-related outbreaks and pseudo-outbreaks: A systematic review
Kakoullis L, Economidou S, Mehrotra P, Panos G, Karampitsakos T, Stratakos G, Tzouvelekis A, Sampsonas F. Bronchoscopy-related outbreaks and pseudo-outbreaks: A systematic review. Infection Control And Hospital Epidemiology 2023, 45: 509-519. PMID: 38099453, DOI: 10.1017/ice.2023.250.Peer-Reviewed Original Research18 years of face transplantation: Adverse outcomes and challenges
Longo B, Pomahac B, Giacalone M, Cardillo M, Cervelli V. 18 years of face transplantation: Adverse outcomes and challenges. Journal Of Plastic Reconstructive & Aesthetic Surgery 2023, 87: 187-199. PMID: 37879143, DOI: 10.1016/j.bjps.2023.09.043.Peer-Reviewed Original ResearchConceptsAllograft lossAdverse outcomesFace transplantationMedian timeStandard of careGoogle Scholar databasesFace transplant teamHeterogeneity of casesAllograft removalChronic rejectionInfectious complicationsIrreversible rejectionMajor complicationsTransplant centersTransplant casesTransplant teamPatient deathPRISMA guidelinesComplicationsSystematic reviewTransplantationScholar databasesSingle center approachSignificant riskPeer-reviewed literaturePrevalence and predictors of long-delayed (> 120 h) chemotherapy-induced nausea and vomiting (CINV)—a systematic review and individual patient data meta-analysis
Chow R, Yin L, Baqri W, Huang R, Boldt G, Younus J, Lock M, Prsic E, Zimmermann C, Herrstedt J. Prevalence and predictors of long-delayed (> 120 h) chemotherapy-induced nausea and vomiting (CINV)—a systematic review and individual patient data meta-analysis. Supportive Care In Cancer 2023, 31: 505. PMID: 37535218, DOI: 10.1007/s00520-023-07978-y.Peer-Reviewed Original ResearchConceptsChemotherapy-induced nauseaIndividual patient dataDay 4Individual patient-level dataPatient dataPatient-level dataStepwise logistic regressionEmetogenic chemotherapyChemotherapy regimenChemotherapy regimensPatient demographicsCochrane CENTRALResultsA totalOverall prevalenceCINVNauseaVomitingPatientsEligible articlesSystematic reviewAntineoplastic agentsStudy authorsLogistic regressionMethodsThis reviewSignificant riskSuicide Risk Assessment, Management, and Mitigation in the Emergency Setting
Powsner S, Goebert D, Richmond J, Takeshita J. Suicide Risk Assessment, Management, and Mitigation in the Emergency Setting. FOCUS The Journal Of Lifelong Learning In Psychiatry 2023, 21: 8-17. PMID: 37205029, PMCID: PMC10172543, DOI: 10.1176/appi.focus.20220072.Peer-Reviewed Original ResearchRisk of suicideEmergency settingIndividual patientsEvidence-based screeningSerious public health issueEmergency department settingBetter clinical assessmentPublic health issueSuicide risk assessmentCommon presentationHospital admissionPsychiatric admissionsDepartment settingLeading causeClinical assessmentED boardingPatientsPsychiatric crisisSuicidal ideationSuicide riskAvailable evidenceHealth issuesSignificant riskAdmissionRiskNonutility of procalcitonin for diagnosing bacterial pneumonia in patients with severe COVID-19
Cohen A, Glick L, Lee S, Kunitomo Y, Tsang D, Pitafi S, Toro P, Ristic N, Zhang E, Carey G, Datta R, Dela Cruz C, Gautam S. Nonutility of procalcitonin for diagnosing bacterial pneumonia in patients with severe COVID-19. European Clinical Respiratory Journal 2023, 10: 2174640. PMID: 36815942, PMCID: PMC9930745, DOI: 10.1080/20018525.2023.2174640.Peer-Reviewed Original ResearchSevere COVID-19Bacterial superinfectionBacterial pneumoniaCOVID-19Lower respiratory culturesSuperimposed bacterial pneumoniaUtility of procalcitoninProcalcitonin measurementImmune biomarkersClinical resemblanceRespiratory culturesImmunomodulatory agentsProcalcitoninPatientsBacterial infectionsSuperinfectionCurve analysisSignificant riskCharacteristic curvePneumoniaTime of cultureDiagnosisInfectionBiomarkers
2022
The COVID-19 Pandemic, Socioeconomic Effects, and Intimate Partner Violence Against Women: A Population-Based Cohort Study in 2020, Iran
Fereidooni R, Mootz J, Sabaei R, Khoshnood K, Heydari ST, Moradian MJ, Taherifard E, Nasirian M, Molavi Vardanjani H. The COVID-19 Pandemic, Socioeconomic Effects, and Intimate Partner Violence Against Women: A Population-Based Cohort Study in 2020, Iran. American Journal Of Public Health 2022, 113: 228-237. PMID: 36302221, PMCID: PMC9850608, DOI: 10.2105/ajph.2022.306839.Peer-Reviewed Original ResearchConceptsSexual intimate partner violenceRisk factorsIntimate partner violenceSocioeconomic statusIranian womenPandemic onsetMain exposure variableSocioeconomic risk factorsLow socioeconomic statusHigher socioeconomic statusCohort studyPandemic prevalencePartner violencePhysical intimate partner violenceHigh incidenceIPV surveyExposure variablesPrevalenceCOVID-19 epidemicSignificant riskWomenIncidenceIPV prevalenceCOVID-19 pandemicIncidence of IPVCOVID-19 outbreak in a state prison: a case study on the implementation of key public health recommendations for containment and prevention
Duarte C, Cameron DB, Kwan AT, Bertozzi SM, Williams BA, McCoy SI. COVID-19 outbreak in a state prison: a case study on the implementation of key public health recommendations for containment and prevention. BMC Public Health 2022, 22: 977. PMID: 35568894, PMCID: PMC9107313, DOI: 10.1186/s12889-022-12997-1.Peer-Reviewed Original ResearchConceptsPublic health recommendationsHealth recommendationsCOVID-19 outbreakCOVID-19 infectionPublic health strategiesInter-facility transferMulti-level interventionsPublic health officialsInfectious disease riskStaff cohortingInfectious disease outbreaksHealth strategiesOutbreak containmentDisease riskHealth officialsHealth OrganizationMedical isolationSignificant riskFuture outbreaksMulti-level determinantsCOVID-19 pandemicAdministrative dataPublic healthRapid testingCarceral settingsThe role of alcohol intake in the pharmacogenetics of treatment with clozapine
Monroy-Jaramillo N, Martínez-Magaña JJ, Pérez-Aldana BE, Ortega-Vázquez A, Montalvo-Ortiz J, López-López M. The role of alcohol intake in the pharmacogenetics of treatment with clozapine. Pharmacogenomics 2022, 23: 371-392. PMID: 35311547, DOI: 10.2217/pgs-2022-0006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAdverse reactionsAlcohol intakeConcomitant useSevere adverse reactionsGood therapeutic effectPrecision medicine approachRefractory psychosisAtypical antipsychoticsInterindividual responseTherapeutic effectClozapineMedicine approachPharmacogenetic studiesSignificant riskIntakePatientsGenetic variantsPharmacogeneticsAntipsychoticsPsychosisCYP1A2ReceptorsAn Analysis of Risk-Assessment Driven Security Restraint Use during the Transport of Forensic Patients.
Wasser TD, Strockbine BA, Hauser LL, Mathew MA, Gay B, Smith HE, Dike CC. An Analysis of Risk-Assessment Driven Security Restraint Use during the Transport of Forensic Patients. The Journal Of The American Academy Of Psychiatry And The Law 2022, 50: 74-83. PMID: 35042737, DOI: 10.29158/jaapl.210050-21.Peer-Reviewed Original ResearchConceptsForensic hospitalState forensic hospitalForensic hospital patientsForensic psychiatric patientsRisk assessment toolHospital patientsRestraint useHigh riskPsychiatric patientsHospital staffPatientsPatient advocatesPatient transportationSignificant riskForensic patientsHospital administratorsTool correlateHospitalRisk
2021
Mental health and behavioural difficulties in adopted children: A systematic review of post-adoption risk and protective factors
Duncan M, Woolgar M, Ransley R, Fearon P. Mental health and behavioural difficulties in adopted children: A systematic review of post-adoption risk and protective factors. Adoption & Fostering 2021, 45: 414-429. DOI: 10.1177/03085759211058358.Peer-Reviewed Original ResearchBehavioral difficultiesMental healthProtective factorsNon-adopted peersFuture researchChild mental healthRigorous methodological criteriaFamily factorsBehavioral outcomesContextual variablesMental health servicesShape interventionsPrevious researchChildrenClinical implicationsWeb of ScienceHealth servicesSystematic reviewGreater riskSociological AbstractsDifficultiesMethodological criteriaSystemic factorsSignificant riskResearchREVeAL-HF Design and Rationale of a Pragmatic Randomized Controlled Trial Embedded Within Routine Clinical Practice
Ahmad T, Yamamoto Y, Biswas A, Ghazi L, Martin M, Simonov M, Hsiao A, Kashyap N, Velazquez EJ, Desai NR, Wilson FP. REVeAL-HF Design and Rationale of a Pragmatic Randomized Controlled Trial Embedded Within Routine Clinical Practice. JACC Heart Failure 2021, 9: 409-419. PMID: 33992566, DOI: 10.1016/j.jchf.2021.03.006.Peer-Reviewed Original ResearchConceptsHeart failurePatient outcomesClinical decision makingN-terminal pro-B-type natriuretic peptide levelsPro-B-type natriuretic peptide levelsPragmatic Randomized Controlled TrialIntravenous diuretic agentsNatriuretic peptide levelsRandomized Controlled TrialsRoutine clinical practiceEvidence-based interventionsElectronic health recordsControlled TrialsPatient populationAccurate prognosticationCommon causeDiuretic agentsPeptide levelsClinical practicePg/TrialsHealth recordsSignificant riskMortalityOutcomes
2020
Risk Factors and Cardiovascular Disease (CVD) Related Outcomes in Hospitalized Patients with Hemophilia 10 Year Follow up
Day J, Gupta A, Abro C, Jung K, Krishnamurti L, Takemoto C, Goel R. Risk Factors and Cardiovascular Disease (CVD) Related Outcomes in Hospitalized Patients with Hemophilia 10 Year Follow up. Blood 2020, 136: 30-31. DOI: 10.1182/blood-2020-136486.Peer-Reviewed Original ResearchCVD risk factorsAcute myocardial infarctionAtherosclerotic coronary artery diseaseCVD outcomesCoronary artery diseaseNationwide Inpatient SamplePrevalent risk factorsRisk factorsCardiovascular diseaseHaemophilia populationOrder of frequencyHemophilia AArtery diseaseHeart failureHospitalized patientsHaemophilia patientsMean agePrevalence ratesJohns Hopkins Institutional Review BoardUtilization Project Nationwide Inpatient SampleUnadjusted prevalence ratesCardiovascular risk factorsSignificant riskCrude prevalence rateICD-9 codesAnalysis of DNA Methylation Changes in Mice Mediated by Early‐life Exposure to the Antidepressant S‐citalopram
Rodriquez M, Shetty M, Black E, Kretschmar M, Perley D, De Kumar B, Henry L. Analysis of DNA Methylation Changes in Mice Mediated by Early‐life Exposure to the Antidepressant S‐citalopram. The FASEB Journal 2020, 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.06398.Peer-Reviewed Original ResearchMethylation changesSelective serotonin reuptake inhibitorsGenome-wide scaleDNA methylation changesSingle amino acid substitutionDNA methylation analysisSpecific methylation changesAmino acid substitutionsExpression changesMolecular mechanismsAcid substitutionsMethylation analysisSerotonin transporter blockadeSerotonin reuptake inhibitorsEarly life exposurePost-analysis methodsEarly developmentMice MediatedTransgenic miceReuptake inhibitorsTransporter blockadeMale miceS-citalopramSerotonin transporterSignificant riskUmbilical catheter-associated complications in a level IV neonatal intensive care unit
Levit OL, Shabanova V, Bizzarro MJ. Umbilical catheter-associated complications in a level IV neonatal intensive care unit. Journal Of Perinatology 2020, 40: 573-580. PMID: 31911645, DOI: 10.1038/s41372-019-0579-3.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitIntensive care unitLevel IV neonatal intensive care unitCatheter-associated complicationsUmbilical arterial catheterUmbilical cathetersCare unitCatheter useArterial catheterArterial catheter useUmbilical venous catheterVenous catheter useObservational cohort studyCatheter dwell timeCohort studyComplication rateCumulative incidenceVenous cathetersCox regressionResultsFifty-oneComplicationsCatheterEvent ratesSignificant riskLower percentage
2018
A Novel Approach to Serial Amnioinfusion in a Case of Premature Rupture of Membranes Near the Limit of Viability
Kohari K, Mehlhaff K, Merriam A, Abdel-Razeq S, Grechukhina O, Leon-Martinez D, Bahtiyar MO. A Novel Approach to Serial Amnioinfusion in a Case of Premature Rupture of Membranes Near the Limit of Viability. American Journal Of Perinatology Reports 2018, 08: e180-e183. PMID: 30250757, PMCID: PMC6138466, DOI: 10.1055/s-0038-1669964.Peer-Reviewed Original ResearchLimit of viabilityIntra-amniotic infectionSerial transabdominal amnioinfusionsIntra-amniotic infusionSerial amnioinfusionsMaternal morbidityPlacental abruptionPreterm laborTransabdominal amnioinfusionPrelabor rupturePulmonary hypoplasiaPremature rupturePersistent oligohydramniosNormal salineNeonatal survivalLatency periodClinical scenariosAdditional riskSignificant riskAmnioinfusionRiskFetusesInfectionImmediate riskRupture
2017
Surgical Management of Pulmonary Embolism
Jung J, Bonde P. Surgical Management of Pulmonary Embolism. 2017, 405-418. DOI: 10.1007/978-3-319-65226-9_31.Peer-Reviewed Original ResearchChronic thromboembolic pulmonary hypertensionDeep vein thrombosisPulmonary embolismVenous thromboembolismPathophysiology of PERight heart dysfunctionThromboembolic pulmonary hypertensionAcute pulmonary embolismSpectrum of disordersPulmonary endarterectomyPulmonary embolectomyPulmonary hypertensionVein thrombosisHeart failureSurgical managementOperative managementPulmonary vasculatureSurgical interventionHeart dysfunctionEffective treatmentMechanical occlusionEmbolismSignificant riskEndarterectomyEmbolectomy
2016
Factors affecting carriage and intensity of infection of Calodium hepaticum within Norway rats (Rattus norvegicus) from an urban slum environment in Salvador, Brazil
WALKER R, CARVALHO-PEREIRA T, SERRANO S, PEDRA G, HACKER K, TAYLOR J, MINTER A, PERTILE A, PANTI-MAY A, CARVALHO M, SOUZA FN, NERY N, RODRIGUES G, BAHIENSE T, REIS MG, KO AI, CHILDS JE, BEGON M, COSTA F. Factors affecting carriage and intensity of infection of Calodium hepaticum within Norway rats (Rattus norvegicus) from an urban slum environment in Salvador, Brazil. Epidemiology And Infection 2016, 145: 334-338. PMID: 27780498, PMCID: PMC6247895, DOI: 10.1017/s0950268816002259.Peer-Reviewed Original ResearchConceptsIntensity of infectionNorway ratsIndependent risk factorC. hepaticumHumans of exposureUrban slum environmentsCalodium hepaticumUrban slum areaSlum areasLiver involvementMammalian hostsRisk factorsInfective eggsRatsCarriage levelsSignificant riskInfectionUrban slumsCarriageFurther studiesSub-standard living conditionsRiskZoonotic pathogensSlum environmentRodent-borne zoonotic pathogensA Surgeon's Dilemma
Shuman A, Fins J. A Surgeon's Dilemma. The Hastings Center Report 2016, 46: 9-10. PMID: 27150413, DOI: 10.1002/hast.586.Peer-Reviewed Original ResearchTreatment-refractory cancerCritically ill patientsObstructing tumorAwake tracheotomyIntraoperative deathsProgressive diseasePulmonary embolismAggressive resuscitationPerioperative windowMechanical ventilationIll patientsDifficulty breathingEmergency roomPatientsPatient's desireSurgeonsSurgical staffSignificant riskYoung mothersMortality conferencesMothersEmbolizationSurgeryTracheotomyTumor
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply