Lauren Cohn, MD

Emeritus Faculty

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Additional Titles

Associate Director, MD/PHD Program

Director, Newington VA Pulmonary Clinic, Medicine, VA Connecticut Health System

Contact Info

lauren.cohn@yale.edu

203.785.3627

Pulmonary, Critical Care & Sleep Medicine

PO Box 208057, 300 Cedar Street

New Haven, CT 06520-8057

United States

About

Titles

Emeritus Faculty

Associate Director, MD/PHD Program

Positions outside Yale

Director, Newington VA Pulmonary Clinic, Medicine, VA Connecticut Health System

Appointments

Pulmonary, Critical Care & Sleep Medicine
Senior Research Scientist
Secondary
Pulmonary, Critical Care & Sleep Medicine

Asthma & Airways Disease Program
Internal Medicine
MD-PhD Program
Pulmonary, Critical Care & Sleep Medicine
Rheumatic Diseases Research Core
Tuberculosis Program
Winchester Center for Lung Disease
Yale New Haven Health System
Yale Ventures

Education & Training

Post-doctoral Fellow: Yale School of Medicine (1995)

Fellow: Columbia Presbyterian Medical Center (1993)

Post-Doctoral Research Fellow: Columbia University College of Physicians and Surgeons (1993)

Clinical Fellow: Columbia University College of Physicians and Surgeons (1991)

Resident: Columbia-Presbyterian Medical Center (1990)

MD: University of Minnesota (1987)

BA: Smith College, Biology (1982)

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Research

Overview

Medical Research Interests

Airway Management; Asthma; Epithelium; Lung; Lung Diseases; Metaplasia

Cohn Lab
View Lab Website

Research at a Glance

Yale Co-Authors

Frequent collaborators of Lauren Cohn's published research.

Robert Homer, MD, PhD
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View 11 Common Publications
Geoffrey Chupp, MD
View Full Profile
View 5 Common Publications
Jose Gomez Villalobos, MD, MS
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View 3 Common Publications
Xiting Yan, PhD
View Full Profile
View 3 Common Publications
Brian Clark, MD
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View 2 Common Publications
Farida Ahangari, MD
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View 2 Common Publications

Publications

2023

2022

The long-term effect of dupilumab on dyspnea, sleep, and activity in oral corticosteroid-dependent severe asthma
Sher L, Passalacqua G, Taillé C, Cohn L, Daizadeh N, Pandit-Abid N, Soler X, Khodzhayev A, Jacob-Nara J, Deniz Y, Rowe P, Nag A, Zhang Y. The long-term effect of dupilumab on dyspnea, sleep, and activity in oral corticosteroid-dependent severe asthma. Annals Of Allergy Asthma & Immunology 2022, 130: 298-304. PMID: 36509407, DOI: 10.1016/j.anai.2022.12.002.
Peer-Reviewed Original Research
MeSH Keywords and Concepts

2018

Eosinophil Binding and Activation is Regulated Through the Coordinated Expression of miR-1 Endothelial Targets
Korde A, Ahangari F, Mehta S, Cohn L, Gonzalez A, Takyar S. Eosinophil Binding and Activation is Regulated Through the Coordinated Expression of miR-1 Endothelial Targets. American Journal Of Respiratory And Critical Care Medicine 2018, 197: a1293-a1293. DOI: 10.1164/ajrccm-conference.2018.197.1_meetingabstracts.a1293.
Peer-Reviewed Original Research

2017

Short Palate Lung Nasal Epithelium Clone 1 (SPLUNC1): A Regulator of Early Epithelial Responses to Pseudomonas Aeruginosa
Britto-Leon C, Niu N, Sharma L, Cohn L, Dela Cruz C. Short Palate Lung Nasal Epithelium Clone 1 (SPLUNC1): A Regulator of Early Epithelial Responses to Pseudomonas Aeruginosa. American Journal Of Respiratory And Critical Care Medicine 2017, 195: a2788-a2788. DOI: 10.1164/ajrccm-conference.2017.195.1_meetingabstracts.a2788.
Peer-Reviewed Original Research
Concepts
Emerging Role of YKL-40 In IL-13 Induced Inflammation in Monocyte Cells
Nezgovorova V, Chen X, Liu Q, Liang A, Yan X, Niu N, Gomez J, Cohn L, Hu B, Unutmaz D, Chupp G. Emerging Role of YKL-40 In IL-13 Induced Inflammation in Monocyte Cells. American Journal Of Respiratory And Critical Care Medicine 2017, 195: a5304-a5304. DOI: 10.1164/ajrccm-conference.2017.195.1_meetingabstracts.a5304.
Peer-Reviewed Original Research
Blocking YKL-40 (Chitinase-Like Protein Chitinase 3) Attenuates IL-13-Induced Airway Hyper-Responsiveness in a Human Precision Cut Lung Slice Model
Koziol-White C, Nezgovorova V, Cohn L, Chupp G, Panettieri R. Blocking YKL-40 (Chitinase-Like Protein Chitinase 3) Attenuates IL-13-Induced Airway Hyper-Responsiveness in a Human Precision Cut Lung Slice Model. American Journal Of Respiratory And Critical Care Medicine 2017, 195: a4948-a4948. DOI: 10.1164/ajrccm-conference.2017.195.1_meetingabstracts.a4948.
Peer-Reviewed Original Research

2016

SPLUNC1 Dysregulation in the Sputum of Stable Adult Cystic Fibrosis Subjects
Britto C, Niu N, Bruscia E, Barone C, Egan M, Cohn L. SPLUNC1 Dysregulation in the Sputum of Stable Adult Cystic Fibrosis Subjects. American Journal Of Respiratory And Critical Care Medicine 2016, 193: a2881-a2881. DOI: 10.1164/ajrccm-conference.2016.193.1_meetingabstracts.a2881.
Peer-Reviewed Original Research
Clinical and Molecular Characterization of the CHI3L1/YKL-40 Severe Asthma Endotypes
Gomez J, Crisafi G, Holm C, Jarjour N, Hawkins G, Meyers D, Bleecker E, Reibman J, Cohn L, Chupp G. Clinical and Molecular Characterization of the CHI3L1/YKL-40 Severe Asthma Endotypes. American Journal Of Respiratory And Critical Care Medicine 2016, 193: a4346-a4346. DOI: 10.1164/ajrccm-conference.2016.193.1_meetingabstracts.a4346.
Peer-Reviewed Original Research
SPLUNC1 Regulates LPS-Induced Innate Immune Activation and Lung Neutrophilic Inflammation
Britto C, Niu N, Cohn L. SPLUNC1 Regulates LPS-Induced Innate Immune Activation and Lung Neutrophilic Inflammation. American Journal Of Respiratory And Critical Care Medicine 2016, 193: a4793-a4793. DOI: 10.1164/ajrccm-conference.2016.193.1_meetingabstracts.a4793.
Peer-Reviewed Original Research

See All Publications

Clinical Trials

Current Trials

EPIPHANY study for people with moderate to severe asthma
IRB ID2000032380RoleSub InvestigatorPrimary Completion Date12/31/2024
Recruiting Participants
Asthma
Observational Study of Characteristics, Treatment and Outcomes With Severe Asthma in the United States (CHRONICLE)
IRB ID2000023925RoleSub InvestigatorPrimary Completion Date12/02/2022
Recruiting ParticipantsGenderBothAge18+ years
Women's HealthMen's HealthAsthma

Academic Achievements & Community Involvement

Activities

activity
Editorial Board, American Journal of Respiratory Cell and Molecular Biology
07/01/2008 - PresentJournal ServiceAssociate Editor
Details
activity
Member, Allergy, Immunology and Inflammation Assembly
07/01/1993 - PresentProfessional OrganizationsCommittee Member
activity
Journal of Clinical Investigation, Journal of Immunology, American Journal of Respiratory and Critical Care Medicine, American Journal of Respiratory Cell and Molecular Biology, Mucosal Immunology, Journal of Allergy and Clinical Immunology, Chest and others.
1998 - PresentJournal ServiceReviewer
activity
Dupilimab Asthma Advisory Boards (multiple)
2018 - PresentAdvisory BoardsAdvisor
Details
activity
Pieris Asthma Advisory Board
2018 - PresentAdvisory BoardsAdvisor
Details

View full list of activities

Honors

honor
Alumni Achievement Award
04/27/2018National AwardSarnoff Foundation
Details
honor
Research Core Center Pilot Funding
08/03/2009Yale School of Medicine AwardYale Rheumatic Diseases
Details
honor
Career Investigator Award
07/01/2004National AwardAmerican Lung Association
Details
honor
NIH Award (declined)
07/03/2000National AwardCystic Fibrosis Foundation
Details
honor
Mentored Clinical Scientist Award, 50th Anniversary Celebration
07/01/1998National AwardNIH/NHLBI
Details

View full list of honors

News & Links

News

Related Links
- Find Dr. Cohn's publications on PubMed
- New procedure is a breakthrough in helping asthmatics breathe

Get In Touch

Contacts

lauren.cohn@yale.edu

Academic Office Number

203.785.3627

Appointment Number

203.495.2410

Clinic Fax Number

203.737.5453

Mailing Addresses

Pulmonary, Critical Care & Sleep Medicine

PO Box 208057, 300 Cedar Street

New Haven, CT 06520-8057

United States

Pulmonary, Critical Care & Sleep Medicine

333 Cedar Street, P.O. Box 208057

New Haven, CT 06511

United States

Locations

The Anlyan Center
Academic Office
300 Cedar Street, Ste S433
New Haven, CT 06519
Get Directions

Additional Titles

Contact Info

Titles

Positions outside Yale

Appointments

Pulmonary, Critical Care & Sleep Medicine

Other Departments & Organizations

Education & Training

Overview

Medical Research Interests

Cohn Lab

Research at a Glance

Yale Co-Authors

Robert Homer, MD, PhD

Geoffrey Chupp, MD

Jose Gomez Villalobos, MD, MS

Xiting Yan, PhD

Brian Clark, MD

Farida Ahangari, MD

Publications

2023

2022

2018

2017

2016

Clinical Trials

Current Trials

Activities

Editorial Board, American Journal of Respiratory Cell and Molecular Biology

Member, Allergy, Immunology and Inflammation Assembly

Journal of Clinical Investigation, Journal of Immunology, American Journal of Respiratory and Critical Care Medicine, American Journal of Respiratory Cell and Molecular Biology, Mucosal Immunology, Journal of Allergy and Clinical Immunology, Chest and others.

Dupilimab Asthma Advisory Boards (multiple)

Pieris Asthma Advisory Board

Honors

Alumni Achievement Award

Research Core Center Pilot Funding

Career Investigator Award

NIH Award (declined)

Mentored Clinical Scientist Award, 50th Anniversary Celebration

News

Welcoming a New Faculty Associate Director: Lauren Cohn, MD

Eleven New Professors Appointed in Department of Internal Medicine

New Appointments & Promotions Within Department of Internal Medicine

Related Links

Contacts

Locations

The Anlyan Center