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INFORMATION FOR

    Kristopher Kahle, MD, PhD

    Assistant Professor Adjunct
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    Additional Titles

    Pediatrics, and Cellular and Molecular Physiology

    Director, Neonatal and Congenital Anomaly Neurosurgery

    Contact Info

    kristopher.kahle@yale.edu

    Neurosurgery

    789 Howard Avenue, Tompkins 4

    New Haven, CT 06520

    United States

    About

    Titles

    Assistant Professor Adjunct

    Pediatrics, and Cellular and Molecular Physiology; Director, Neonatal and Congenital Anomaly Neurosurgery

    Biography

    Kristopher T. Kahle, M.D., Ph.D., is an Adjunct Professor of Neurosurgery and Pediatrics and Cellular and Molecular Physiology at Yale School of Medicine, and Director of Neonatal and Congenital Anomaly Neurosurgery in the Division of Pediatric Neurosurgery. He completed his MD and PhD degrees at the Yale School of Medicine under the mentorship of Richard Lifton, and neurosurgical residency at the Massachusetts General Hospital. After residency, Dr. Kahle completed his pediatric neurosurgery fellowship at Boston Children’s Hospital and was Instructor at Harvard Medical School. Dr. Kahle completed a postdoctoral research fellowship with Stephen Elledge and David Clapham at Harvard University. Dr. Kahle’s primary clinical practice includes disorders of neurodevelopment (hydrocephalus, arachnoid cysts, congenital vascular malformations, chiari malformations, spina bifida, and tethered spinal cord) and tumors of the pediatric brain and spinal cord. Dr. Kahle trained in neuroendoscopy, including third ventriculostomy and choroid plexus coagulation, with Dr. Benjamin Warf at Harvard. Dr. Kahle is an attending physician at Yale New Haven Hospital and the Yale New Haven Children’s Hospital. Dr. Kahle’s research is devoted to identifying the genes and pathways that regulate ion and water homeostasis in the developing nervous system, and how genetically-encoded or maladaptive changes in these processes contribute to the cellular, circuit, and behavioral abnormalities in neurodevelopmental disorders and in the traumatized brain. He also uses molecular genetic tools such as whole exome and genome sequencing to discover the molecular determinants of neurodevelopmental diseases, such as congenital hydrocephalus. The goal of his work is to translate advances in basic science into novel therapeutic strategies for pediatric neurosurgical diseases.

    Appointments

    Other Departments & Organizations

    Education & Training

    Pediatric Neurosurgery Fellowship
    Boston Children's Hospital (2015)
    Post-doctoral Research Fellow
    Harvard Medical School (2015)
    Neurosurgery Residency
    Massachusetts General Hospital (2014)
    MD
    Yale School of Medicine (2007)
    PhD
    Yale University, Cellular and Molecular Physiology (2007)

    Research

    Research at a Glance

    Yale Co-Authors

    Frequent collaborators of Kristopher Kahle's published research.

    Publications

    2024

    See All Publications

    Clinical Trials

    Current Trials

    Get In Touch

    Contacts

    Email
    Appointment Number
    Mailing Address

    Neurosurgery

    789 Howard Avenue, Tompkins 4

    New Haven, CT 06520

    United States

    Administrative Support