Bluma Lesch, MD, PhD

Assistant Professor of Genetics

Departments & Organizations


Yale Cancer Center: Genomics, Genetics, and Epigenetics

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Computational Biology and Bioinformatics | Molecular Cell Biology, Genetics and Development


Bluma (Bibi) Lesch works on the genetics and epigenetics of reproduction and development, with a special interest in the evolution of epigenetic and chromatin states in mammals. Understanding the evolution of gene regulation in gametes requires integrating information across a wide range of biological scales, from the regulation of molecules to the development of individuals to the evolution of species. Dr. Lesch’s work brings together these divergent approaches to thinking about biology.

Dr. Lesch earned her B.S. from Yale University in 2003. She obtained her Ph.D. in 2010 from Rockefeller University and her M.D. in 2011 from Weill Cornell Medical College in New York City.  She was a postdoctoral fellow at the Whitehead Institute in Cambridge, MA, from 2011-2017, where she was awarded an NIH Kirschstein postdoctoral fellowship and also named a Hope Funds for Cancer Research postdoctoral fellow.  She received a Burroughs Wellcome Career Award for Medical Scientists in 2015, and returned to New Haven to join the Yale faculty in 2017.

Education & Training

MD Weill Medical College of Cornell University (2011)
PhD Rockefeller University (2010)
BS Yale University (2003)

Honors & Recognition

  • Searle Scholar (2019)

  • Kingsley FellowYale School of Medicine (2017)

  • Burroughs-Wellcome Career Award (2015)

  • Hope Funds for Cancer Research Fellow (2013)

  • NIH Ruth L. Kirschstein Postdoctoral Fellow (2013)

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