2024
Temporal trends in population attributable fractions of modifiable risk factors for dementia: a time-series study of the English Longitudinal Study of Ageing (2004–2019)
Chen S, Underwood B, Cardinal R, Chen X, Chen S, Amin J, Jin H, Huang J, Mueller C, Yan L, Brayne C, Kuper H. Temporal trends in population attributable fractions of modifiable risk factors for dementia: a time-series study of the English Longitudinal Study of Ageing (2004–2019). BMC Medicine 2024, 22: 268. PMID: 38926751, PMCID: PMC11210022, DOI: 10.1186/s12916-024-03464-2.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAgingDementiaEnglandFemaleHumansLongitudinal StudiesMaleMiddle AgedRisk FactorsConceptsPopulation attributable fractionModifiable risk factorsEnglish Longitudinal Study of AgeingOverall PAFLongitudinal Study of AgingEnglish Longitudinal StudyPhysical inactivitySocioeconomic statusStudy of AgingLower educationDementia riskSocial isolationAttributable fractionHearing lossRisk factorsTargeted public health strategiesTraumatic brain injuryProportion of dementiaDeterminants of dementiaSocioeconomic status categoriesEffective public health policiesDevelopment of evidence-basedPublic health strategiesPublic health policiesTime-series study
2022
Life course traumas and cardiovascular disease—the mediating role of accelerated aging
Cao X, Zhang J, Ma C, Li X, Kuo C, Levine ME, Hu G, Allore H, Chen X, Wu X, Liu Z. Life course traumas and cardiovascular disease—the mediating role of accelerated aging. Annals Of The New York Academy Of Sciences 2022, 1515: 208-218. PMID: 35725988, PMCID: PMC10145586, DOI: 10.1111/nyas.14843.Peer-Reviewed Original Research
2020
Linking early life risk factors to frailty in old age: evidence from the China Health and Retirement Longitudinal Study
Li Y, Xue QL, Odden MC, Chen X, Wu C. Linking early life risk factors to frailty in old age: evidence from the China Health and Retirement Longitudinal Study. Age And Ageing 2020, 49: 208-217. PMID: 31957780, PMCID: PMC7047816, DOI: 10.1093/ageing/afz160.Peer-Reviewed Original ResearchConceptsEarly life risk factorsLife risk factorsRisk factorsChildhood health statusRetirement Longitudinal StudyRisk differenceHealth statusChina HealthOlder ageOlder adultsAbsolute risk differenceCross-sectional studyLongitudinal studyUnfavorable socioeconomic statusLate-life frailtyWorse health conditionsChinese older adultsMiddle-income countriesDevelopment of diseaseHigh riskLower riskRepresentative cohortMultinomial regression modelsHealth conditionsFrailty