2023
Vitamin D and infertility
Simpson S, Pal L. Vitamin D and infertility. Current Opinion In Obstetrics & Gynecology 2023, 35: 300-305. PMID: 37266579, DOI: 10.1097/gco.0000000000000887.Peer-Reviewed Original ResearchConceptsPolycystic ovarian syndromeVitamin DGynaecological disordersVitamin D serum levelsOvarian reserve parametersD serum levelsVitamin D deficiencyVitamin D statusDiminished ovarian reserveCommon gynaecological disorderReproductive health burdenHigher pregnancy rateD deficiencyD statusOvarian reserveOvarian syndromeInfertile womenSerum levelsUterine myomaMenstrual regularityEndometriosis patientsInsulin levelsUterine fibroidsHealth burdenPregnancy rateGenital tuberculosis, infertility and assisted reproduction
Mir N, Pal L. Genital tuberculosis, infertility and assisted reproduction. Current Opinion In Obstetrics & Gynecology 2023, 35: 263-269. PMID: 36912346, DOI: 10.1097/gco.0000000000000866.Peer-Reviewed Original ResearchMeSH KeywordsFemaleFertilization in VitroHumansInfertilityInfertility, FemaleReproductionReproductive Techniques, AssistedTuberculosis, Female GenitalConceptsGenital tuberculosisClinical presentationLife-threatening risksGenital TBFetal morbidityInfertile womenCouple infertilityAppropriate screeningTimely treatmentRisk populationsUntreated casesInfertilityAssisted reproductionReproductive technologiesUnique risksTuberculosisRiskPresentationMorbidityIVFEpidemiologyDiagnosisRecent literatureWomen
2008
Characterizing the reproductive hormone milieu in infertile women with diminished ovarian reserve
Pal L, Zhang K, Zeitlian G, Santoro N. Characterizing the reproductive hormone milieu in infertile women with diminished ovarian reserve. Fertility And Sterility 2008, 93: 1074-1079. PMID: 19100532, DOI: 10.1016/j.fertnstert.2008.10.069.Peer-Reviewed Original ResearchConceptsDiminished ovarian reserveReproductive hormone profilesOvarian reserveInfertile womenUrinary excretionMenstrual cycleHealthy controlsHormone profilesAge-comparable healthy controlsUrinary FSH levelsProspective observational studyEarly follicular phaseEntire menstrual cycleAge-comparable controlsMetabolites of estrogenFSH levelsHormone milieuInfertility practiceMenopause transitionUrine voidsFollicular phaseEstrone conjugatesFSH surgeObservational studyMAIN OUTCOMEDiminished ovarian reserve in a woman with a balanced 13;21 translocation
Kummer N, Martin JR, Pal L. Diminished ovarian reserve in a woman with a balanced 13;21 translocation. Fertility And Sterility 2008, 91: 931.e3-931.e5. PMID: 18829026, DOI: 10.1016/j.fertnstert.2008.07.1726.Peer-Reviewed Original ResearchConceptsOvarian reservePrimary infertilityDecreased ovarian reserveUniversity Teaching HospitalLaboratory evaluationBalanced autosomal translocationEndocrinologic evaluationConcomitant findingsEarly menopauseInfertility practiceUnknown etiologyCase reportCaucasian womenTeaching hospitalMAIN OUTCOMEFamilial historyReproductive endocrinologySemen analysisBalanced translocationInfertilityPossible roleDiagnosisWomenAutosomal translocationsKaryotype analysisLess is more: increased gonadotropin use for ovarian stimulation adversely influences clinical pregnancy and live birth after in vitro fertilization
Pal L, Jindal S, Witt BR, Santoro N. Less is more: increased gonadotropin use for ovarian stimulation adversely influences clinical pregnancy and live birth after in vitro fertilization. Fertility And Sterility 2008, 89: 1694-1701. PMID: 18440515, PMCID: PMC2601677, DOI: 10.1016/j.fertnstert.2007.05.055.Peer-Reviewed Original ResearchConceptsNondonor IVF cyclesClinical pregnancyCycle cancellationLive birthsGonadotropin useIVF cyclesSpontaneous miscarriageOvarian reserve statusOvarian hyperstimulation resultsHigh gonadotropinsOvarian stimulationFertilization cyclesIVF outcomesOocyte yieldWorse prognosisRetrospective studyIVF centerImproved outcomesAggressive approachMAIN OUTCOMEPregnancyIVFHigher likelihoodBirthOutcomes
1998
Malignancy may adversely influence the quality and behaviour of oocytes.
Pal L, Leykin L, Schifren J, Isaacson K, Chang Y, Nikruil N, Chen Z, Toth T. Malignancy may adversely influence the quality and behaviour of oocytes. Human Reproduction 1998, 13: 1837-1840. PMID: 9740435, DOI: 10.1093/humrep/13.7.1837.Peer-Reviewed Original ResearchConceptsMalignant diseaseMalignant disordersAge-matched patientsCell of originTubal infertilityIVF cyclesOvarian stimulationDefinitive treatmentCase seriesCertain malignanciesNeoplastic processPatientsComparable total numberMature oocytesMalignancyFertilization rateDiseasePotential fertilityApparent adverse influenceOocytesPoor qualityDisordersTotal numberAdverse influenceInfertility