2015
Enteric‐coated mycophenolate sodium given in combination with tacrolimus has a lower incidence of serious infections in Asian renal‐transplant recipients compared with mycophenolate mofetil
Feng J, Zhang L, Zhao P, Bow L, Tian J. Enteric‐coated mycophenolate sodium given in combination with tacrolimus has a lower incidence of serious infections in Asian renal‐transplant recipients compared with mycophenolate mofetil. International Journal Of Clinical Practice Supplement 2015, 69: 1-7. PMID: 26176848, DOI: 10.1111/ijcp.12660.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdultChinaDose-Response Relationship, DrugEnzyme InhibitorsFemaleFollow-Up StudiesGraft RejectionHumansImmunosuppressive AgentsIncidenceKidney TransplantationMaleMiddle AgedMycophenolic AcidProspective StudiesSurgical Wound InfectionTablets, Enteric-CoatedTacrolimusTransplant RecipientsConceptsAsian renal transplant recipientsRenal transplant recipientsEnteric-coated mycophenolate sodiumEC-MPSMycophenolate sodiumMMF groupIncidence of infectionMycophenolate mofetilSerious infectionsAdverse eventsLower incidenceTherapeutic effectLive donor kidney transplant recipientsInfection rateGastro-intestinal adverse eventsClinical trial registration numberIncidence of biopsyPosttransplant infection ratesTimes of diarrheaKidney transplant recipientsSerum creatinine levelsTRIAL REGISTRATION NUMBEREnteric-coated formulationAcute rejectionRenal transplantation
2001
Use of cryopreserved cadaveric vein allograft for hemodialysis access precludes kidney transplantation because of allosensitization
Benedetto B, Lipkowitz G, Madden R, Kurbanov A, Hull D, Miller M, Bow L. Use of cryopreserved cadaveric vein allograft for hemodialysis access precludes kidney transplantation because of allosensitization. Journal Of Vascular Surgery 2001, 34: 139-142. PMID: 11436087, DOI: 10.1067/mva.2001.114206.Peer-Reviewed Original ResearchConceptsVein allograftsHemodialysis accessPRA valuesControl cohortPRA assaysWaiting listKidney transplantation waiting listPanel-reactive antibodies valuesPotential kidney transplant recipientsUniversity-affiliated medical centerMajor histocompatibility complex IKidney transplant recipientsHistory of transfusionTransplant waiting listTransplantation waiting listMean PRANonimmunosuppressed individualsHemodialysis populationKidney transplantationPrior transplantationTransplant recipientsConsecutive patientsProsthetic graftsAntibody valuesKidney failure
2000
Modulation of efficacies and pharmacokinetics of antibiotics by granulocyte colony-stimulating factor in neutropenic mice with multidrug-resistant Enterococcus faecalis infection
Onyeji C, Nicolau D, Nightingale C, Bow L. Modulation of efficacies and pharmacokinetics of antibiotics by granulocyte colony-stimulating factor in neutropenic mice with multidrug-resistant Enterococcus faecalis infection. Journal Of Antimicrobial Chemotherapy 2000, 46: 429-436. PMID: 10980170, DOI: 10.1093/jac/46.3.429.Peer-Reviewed Original ResearchConceptsGranulocyte colony-stimulating factorG-CSFColony-stimulating factorInfected animalsNeutropenic miceFaecalis infectionDisposition of vancomycinNon-neutropenic animalsEnterococcus faecalis infectionPharmacokinetics of antibioticsInduction of neutropeniaConcentration-time curveEfficacy of gentamicinDose-dependent increaseE. faecalis infectionNeutropenic patientsPharmacokinetic interactionsDosing regimensSame infectionPlasma clearanceUseful adjunctGentamicinInfectionVancomycinMice
1999
Influence of adjunctive interferon-γ on treatment of gentamicin- and vancomycin-resistant Enterococcus faecalis infection in mice
Onyeji C, Bui K, Nicolau D, Nightingale C, Bow L, Quintiliani R. Influence of adjunctive interferon-γ on treatment of gentamicin- and vancomycin-resistant Enterococcus faecalis infection in mice. International Journal Of Antimicrobial Agents 1999, 12: 301-309. PMID: 10493606, DOI: 10.1016/s0924-8579(99)00055-2.Peer-Reviewed Original ResearchConceptsIFN-gammaFaecalis infectionDisposition of gentamicinInfected neutropenic miceNon-neutropenic miceTreatment of gentamicinSerious enterococcal infectionsEnterococcus faecalis infectionNew treatment optionsE. faecalis infectionOutcome of therapyActivity of gentamicinE. faecalis clinical isolatesDose-dependent mannerPharmacokinetic interactionsConcurrent administrationDosing regimensNeutropenic miceCombination therapyInfectious burdenTreatment optionsEnterococcal infectionsIntraperitoneal inoculationClinical isolatesInfected animals
1997
Local urokinase delivery with the Channel balloon: Device safety, pharmacokinetics of intracoronary drug delivery, and efficacy of thrombolysis
Mitchel J, Barry J, Bow L, Alberghini T, Abbas S, McKay R. Local urokinase delivery with the Channel balloon: Device safety, pharmacokinetics of intracoronary drug delivery, and efficacy of thrombolysis. Catheterization And Cardiovascular Interventions 1997, 41: 254-260. PMID: 9213023, DOI: 10.1002/(sici)1097-0304(199707)41:3<254::aid-ccd5>3.0.co;2-5.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, Balloon, CoronaryAnimalsCell DivisionDrug Delivery SystemsEquipment DesignEquipment SafetyFeasibility StudiesFemaleFibrinolytic AgentsIliac ArteryMaleMuscle, Smooth, VascularProliferating Cell Nuclear AntigenSwineThrombolytic TherapyTreatment OutcomeTunica MediaUrokinase-Type Plasminogen ActivatorConceptsLocal urokinase deliveryConventional balloon angioplastyBalloon angioplastyDrug infusionDrug depositionPorcine modelLocal drug delivery catheterLocal deliveryDrug delivery catheterEfficacy of thrombolysisComparative histologic studyCatheter infusionBalloon useVessel traumaCoronary arteryLocal infusionThrombolytic techniquesIntracoronary useHistologic changesBalloon inflationIntramural depositionHistologic studyArtery ratioCoronary vesselsAnesthetized swineLocal delivery of c‐myb antisense oligonucleotides during balloon angioplasty
Azrin M, Mitchel J, Bow L, Pedersen C, Cartun R, Aretz T, Waters D, McKay R. Local delivery of c‐myb antisense oligonucleotides during balloon angioplasty. Catheterization And Cardiovascular Interventions 1997, 41: 232-240. PMID: 9213020, DOI: 10.1002/(sici)1097-0304(199707)41:3<232::aid-ccd2>3.0.co;2-7.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, Balloon, CoronaryAnimalsAutoradiographyCell DivisionCoronary DiseaseCoronary VesselsDrug Delivery SystemsFeasibility StudiesFemaleLymphocyte ActivationMiceMicroscopy, FluorescenceMuscle, Smooth, VascularOligonucleotides, AntisenseProliferating Cell Nuclear AntigenProto-Oncogene ProteinsProto-Oncogene Proteins c-mybSwineTrans-ActivatorsConceptsSmooth muscle cell proliferationMuscle cell proliferationIntraluminal deliveryBalloon angioplastyCell proliferationLess cellular proliferationQuantitative immunohistochemical stainingCatheter-based systemC-MybC-myb antisenseCell nuclear antigenArterial injuryPeripheral arteriesLymphocyte proliferationContralateral vesselCarotid arteryImmunohistochemical stainingAngioplastyArterial mediaArterial segmentsNuclear antigenLocal deliveryCellular proliferationArteryProliferation
1995
Enhanced intracoronary thrombolysis with urokinase using a novel, local drug delivery system. In vitro, in vivo, and clinical studies.
Mitchel J, Fram D, Palme D, Foster R, Hirst J, Azrin M, Bow L, Eldin A, Waters D, McKay R. Enhanced intracoronary thrombolysis with urokinase using a novel, local drug delivery system. In vitro, in vivo, and clinical studies. Circulation 1995, 91: 785-93. PMID: 7828307, DOI: 10.1161/01.cir.91.3.785.Peer-Reviewed Original ResearchConceptsDispatch catheterLocal infusionEnd-hole catheterU urokinaseCatheter infusionIntracoronary thrombusAngioplasty siteUrokinase administrationLocal drug delivery systemIntracoronary thrombolysisUrokinase infusionBalloon angioplastySystemic bolusIntramural depositionNew local drug delivery systemDistal coronary flowLocal urokinase deliveryLocal urokinase infusionThrombus-containing stenosesConventional balloon angioplastyInfusion of urokinaseInfusion of salinePorcine coronary arteriesSystemic fibrinolytic stateCardiac catheterization laboratory
1994
Inhibition of platelet deposition and lysis of intracoronary thrombus during balloon angioplasty using urokinase-coated hydrogel balloons.
Mitchel J, Azrin M, Fram D, Hong M, Wong S, Barry J, Bow L, Curley T, Kiernan F, Waters D. Inhibition of platelet deposition and lysis of intracoronary thrombus during balloon angioplasty using urokinase-coated hydrogel balloons. Circulation 1994, 90: 1979-1988. PMID: 7923688, DOI: 10.1161/01.cir.90.4.1979.Peer-Reviewed Original ResearchConceptsLocal urokinase deliveryVivo balloon angioplastyIntracoronary thrombusBalloon angioplastyPlatelet depositionThrombotic closureDistal embolizationAngioplasty siteAbrupt closureArterial wallHydrogel balloonContralateral control arteriesContralateral control vesselsIntramural drug deliveryVivo studiesConventional balloon angioplastyNew Zealand rabbitsU urokinaseConventional angioplastyBalloon dilatationClinical efficacyReflow phenomenonIliac arteryBlood exposureControl arteries
1993
Causes of late graft failure in cadaveric renal transplantation.
Bergmann L, Roper L, Bow L, Hull D, Bartus S, Schweizer R. Causes of late graft failure in cadaveric renal transplantation. Transplantation Proceedings 1993, 25: 1340-1. PMID: 8442136.Peer-Reviewed Original Research
1992
Late graft loss in cadaveric renal transplantation.
Bergmann L, Roper L, Bow L, Hull D, Bartus S, Schweizer R. Late graft loss in cadaveric renal transplantation. Transplantation Proceedings 1992, 24: 2718-9. PMID: 1465913.Peer-Reviewed Original Research
1989
Transplantation of cadaver kidneys from pediatric and older donors.
Bow L, Roper L, Bartus S, Hull D, Schweizer R. Transplantation of cadaver kidneys from pediatric and older donors. Transplantation Proceedings 1989, 21: 1938-9. PMID: 2652632.Peer-Reviewed Original Research
1986
USE OF TWO DONOR-SPECIFIC TRANSFUSIONS FOR LIVING -RELATED DONOR KIDNEY TRANSPLANTATION
Schweizer R, Bartus S, Rovelli M, Bow L. USE OF TWO DONOR-SPECIFIC TRANSFUSIONS FOR LIVING -RELATED DONOR KIDNEY TRANSPLANTATION. Transplantation 1986, 42: 564-567. PMID: 3538543, DOI: 10.1097/00007890-198611000-00026.Peer-Reviewed Original Research
1982
Serologic considerations in donor-specific transfusion therapy for kidney transplantation.
Schweizer R, Bow L, Generas D, Bartus S. Serologic considerations in donor-specific transfusion therapy for kidney transplantation. Transplantation Proceedings 1982, 14: 374-7. PMID: 6810522.Peer-Reviewed Original Research