2022
PRESENCE OF BRCA MUTATIONS AND A PRE-CHEMOTHERAPY AMH LEVEL OF < 2ng/ML STRONGLY PREDICT RISK OF AMENORRHEA IN WOMEN WITH BREAST CANCER
Oktay K, Turan V, Bedoschi G, Goldfarb S, Bang H. PRESENCE OF BRCA MUTATIONS AND A PRE-CHEMOTHERAPY AMH LEVEL OF < 2ng/ML STRONGLY PREDICT RISK OF AMENORRHEA IN WOMEN WITH BREAST CANCER. Fertility And Sterility 2022, 118: e231. DOI: 10.1016/j.fertnstert.2022.08.652.Peer-Reviewed Original ResearchFemale Infertility
Oktay K, Taylan E. Female Infertility. 2022, 1376-1381. DOI: 10.1093/med/9780198870197.003.0165.Peer-Reviewed Original ResearchFertility preservationOvarian insufficiencyOvarian follicle reservePreservation of fertilityReproductive-age womenEffective treatment optionOvarian endocrine functionAntineoplastic treatmentSurgical interventionFollicle reserveTreatment optionsAge womenFemale infertilityEndocrine functionPsychosocial healthChromosomal disordersReproductive technologiesWomenImproved qualityModern healthcareIrreversible lossInfertilityInsufficiencyChapter 19 Ovarian Tissue Cryopreservation for Delaying Childbearing and Menopause
Oktay K, Marin L. Chapter 19 Ovarian Tissue Cryopreservation for Delaying Childbearing and Menopause. 2022, 193-201. DOI: 10.1016/b978-0-12-823344-3.00003-0.Peer-Reviewed Original ResearchOvarian tissue cryopreservationHealthy womenTissue cryopreservationOvarian tissue harvestingOvarian tissue freezingRisk-benefit assessmentOvarian cryopreservationClinical guidelinesReproductive yearsAmount of tissueMedical indicationsReproductive agingTransplantation techniquesTissue harvestingMenopauseTransplantationWomenTissue freezingCryopreservationChapter 11 Preoperative Evaluation and Preparation for Ovarian Tissue Transplant Surgery
Oktay K, Turan V. Chapter 11 Preoperative Evaluation and Preparation for Ovarian Tissue Transplant Surgery. 2022, 109-115. DOI: 10.1016/b978-0-12-823344-3.00009-1.Peer-Reviewed Original ResearchPreoperative evaluationTransplantation surgeryFertility preservation methodsOvarian tissue cryopreservationOvarian autotransplantationOvarian stimulationHealthy babyTransplant surgeryPrepubertal girlsTissue cryopreservationSurgeryWomenPreparation of womenOnly optionAutotransplantationChemotherapyBabiesEvaluationChapter 18 Approach to Ovarian Stimulation and In Vitro Fertilization in Patients With Transplanted Ovarian Tissue
Oktay K, Babayev S. Chapter 18 Approach to Ovarian Stimulation and In Vitro Fertilization in Patients With Transplanted Ovarian Tissue. 2022, 185-192. DOI: 10.1016/b978-0-12-823344-3.00010-8.Peer-Reviewed Original ResearchOvarian stimulationOvarian autotransplantsIVF outcomesOvarian tissueOptimal ovarian stimulationOvarian stimulation cyclesStandard ovarian stimulationTransplanted ovarian tissueFollicular growth patternOvarian transplantsExtrapelvic locationsStimulation cyclesVitro FertilizationSame womenStimulationWomenAutotransplantsSignificant differencesFertilization protocolsOutcomesTissueGrowth patternPatientsTransplantAvailable data
2021
Delaying Reproductive Aging by Ovarian Tissue Cryopreservation and Transplantation: Is it Prime Time?
Oktay K, Marin L, Petrikovsky B, Terrani M, Babayev S. Delaying Reproductive Aging by Ovarian Tissue Cryopreservation and Transplantation: Is it Prime Time? Trends In Molecular Medicine 2021, 27: 753-761. PMID: 33549473, PMCID: PMC8427891, DOI: 10.1016/j.molmed.2021.01.005.Peer-Reviewed Original ResearchConceptsOvarian tissue cryopreservationTissue cryopreservationHealthy womenFertility preservation proceduresOvarian endocrine functionRisk-benefit assessmentOvarian cryopreservationEndocrine functionMedical indicationsOvarian tissueReproductive agingReproductive medicinePreservation proceduresAmerican SocietyWomenPrime timeCryopreservationResearch guidelinesAutotransplantationMenopauseTransplantation
2020
Impact of adjuvant chemotherapy or tamoxifen-alone on the ovarian reserve of young women with breast cancer
Goldfarb S, Turan V, Bedoschi G, Taylan E, Abdo N, Cigler T, Bang H, Patil S, Dickler M, Oktay K. Impact of adjuvant chemotherapy or tamoxifen-alone on the ovarian reserve of young women with breast cancer. Breast Cancer Research And Treatment 2020, 185: 165-173. PMID: 32930927, PMCID: PMC7877450, DOI: 10.1007/s10549-020-05933-7.Peer-Reviewed Original ResearchConceptsAnti-Mullerian hormoneOvarian reserveAdjuvant chemotherapyBreast cancerAMH levelsChemotherapy regimensCompletion of ACSerum AMH levelsAdjuvant tamoxifenAMH recoveryChemotherapy groupPrimary diagnosisBaseline ageMethodsOne hundredAMH assessmentRegimensChemotherapyYoung womenTamoxifenSignificant recoveryCancerMixed effects modelsMonthsTreatment effectsWomen
2019
Ovarian Stimulation in Women with Breast Cancer
Turan V, Oktay K. Ovarian Stimulation in Women with Breast Cancer. 2019, 105-115. DOI: 10.1007/978-3-030-24086-8_10.Peer-Reviewed Original ResearchFertility preservation optionsOvarian stimulationBreast cancerPreservation optionsEffective fertility preservation optionsEstrogen-sensitive malignanciesReproductive-aged womenCommon cancer typesCytotoxic chemotherapyGonadal failureAged womenOocyte cryopreservationNumber of womenCancer typesCancerWomenStimulationTreatmentHigh levelsChemotherapyPatientsMalignancyOptionsRadiotherapyEstradiolFertility preservation in gynecologic cancers
Taylan E, Oktay K. Fertility preservation in gynecologic cancers. Gynecologic Oncology 2019, 155: 522-529. PMID: 31604663, DOI: 10.1016/j.ygyno.2019.09.012.Peer-Reviewed Original ResearchConceptsFertility preservationGynecologic cancerFertility-sparing surgical approachCancer survivorship careReproductive-age womenGynecologic malignanciesSurvivorship careSurgical approachTreatment optionsAge womenOvarian cancerNumber of womenCancerWomenReproductive technologiesSignificant proportionCurrent knowledgeReview articleMalignancyReproductive potentialCare
2016
Embryo Cryopreservation in Breast Cancer Patients
Bedoschi G, Oktay K. Embryo Cryopreservation in Breast Cancer Patients. 2016, 39-52. DOI: 10.1007/978-4-431-55963-4_3.Peer-Reviewed Original ResearchBreast cancer patientsCancer patientsFertility preservationEmbryo cryopreservationAdjuvant systemic chemotherapyFertility preservation techniquesOvarian stimulation protocolsBreast cancer casesOvarian stimulationSystemic chemotherapyOvarian reserveIncident casesAromatase inhibitorsBreast cancerCancer casesStimulation protocolPatientsDonor semenCommon typeWomenFuture reproductive potentialCancerPreservation techniquesAttractive strategySpecial consideration
2015
Comparison of random start controlled ovarian stimulation with standard start in letrozole gonadotropin cycles for fertility preservation in women with breast cancer
Bedoschi G, Turan V, Emirdar V, Sonmezer M, Oktay K. Comparison of random start controlled ovarian stimulation with standard start in letrozole gonadotropin cycles for fertility preservation in women with breast cancer. Fertility And Sterility 2015, 104: e267. DOI: 10.1016/j.fertnstert.2015.07.838.Peer-Reviewed Original ResearchSafety of controlled ovarian stimulation with gonadotropins and letrozole in women with BRCA mutations
Kim J, Turan V, Oktay K. Safety of controlled ovarian stimulation with gonadotropins and letrozole in women with BRCA mutations. Fertility And Sterility 2015, 104: e265. DOI: 10.1016/j.fertnstert.2015.07.832.Peer-Reviewed Original ResearchLong-term safety of fertility preservation by ovarian stimulation and concurrent aromatase inhibitor treatment in women with breast cancer.
Oktay K, Turan V, Kim J. Long-term safety of fertility preservation by ovarian stimulation and concurrent aromatase inhibitor treatment in women with breast cancer. Journal Of Clinical Oncology 2015, 33: 9521-9521. DOI: 10.1200/jco.2015.33.15_suppl.9521.Peer-Reviewed Original Research
2013
The impact of long-term tamoxifen treatment on ovarian reserve markers in women with breast cancer: a prospective-longitudinal study
Oktay K, Bedoschi G, Dickler M, Goldfarb S, Turan V, Moy F. The impact of long-term tamoxifen treatment on ovarian reserve markers in women with breast cancer: a prospective-longitudinal study. Fertility And Sterility 2013, 100: s64. DOI: 10.1016/j.fertnstert.2013.07.1879.Peer-Reviewed Original ResearchSafety and feasibility of performing two consecutive Letrozole-FSH stimulation cycles for fertility preservation in women with breast cancer
Bedoschi G, Turan V, Oktay K. Safety and feasibility of performing two consecutive Letrozole-FSH stimulation cycles for fertility preservation in women with breast cancer. Fertility And Sterility 2013, 100: s65. DOI: 10.1016/j.fertnstert.2013.07.1883.Peer-Reviewed Original Research
2011
A multicenter analysis of the predictors of fertility preservation in women with breast cancer: Role of neoadjuvant chemotherapy.
Kim J, Oktay K, Gracia C, Lee S, Morse C, Mersereau J. A multicenter analysis of the predictors of fertility preservation in women with breast cancer: Role of neoadjuvant chemotherapy. Journal Of Clinical Oncology 2011, 29: 9118-9118. DOI: 10.1200/jco.2011.29.15_suppl.9118.Peer-Reviewed Original Research
2010
Access to fertility preservation and post-chemotherapy assisted reproduction in women with breast cancer
Lee S, Heytens E, Ozkavukcu S, Rosen A, Moy F, Oktay K. Access to fertility preservation and post-chemotherapy assisted reproduction in women with breast cancer. Fertility And Sterility 2010, 94: s66. DOI: 10.1016/j.fertnstert.2010.07.258.Peer-Reviewed Original ResearchDoes higher starting dose of FSH stimulation improve fertility preservation cycle outcomes in women with breast cancer?
Oktay K, Lee S. Does higher starting dose of FSH stimulation improve fertility preservation cycle outcomes in women with breast cancer? Fertility And Sterility 2010, 94: s160. DOI: 10.1016/j.fertnstert.2010.07.637.Peer-Reviewed Original ResearchLong-term outcomes and safety of letrozole-FSH protocol in women with breast cancer undergoing fertility preservation: a prospective-controlled study
Oktay K, Lee S, Kim J, Moy F. Long-term outcomes and safety of letrozole-FSH protocol in women with breast cancer undergoing fertility preservation: a prospective-controlled study. Fertility And Sterility 2010, 94: s11. DOI: 10.1016/j.fertnstert.2010.07.041.Peer-Reviewed Original Research
2008
Serum FSH monitoring improves decision making in women undergoing controlled ovarian hyperstimulation with letrozole and follicle stimulating hormone
Oktay K, Kim J, Barad D, Gleicher N, Blanchette H. Serum FSH monitoring improves decision making in women undergoing controlled ovarian hyperstimulation with letrozole and follicle stimulating hormone. Fertility And Sterility 2008, 90: s183-s184. DOI: 10.1016/j.fertnstert.2008.07.779.Peer-Reviewed Original Research