2021
Pazopanib ameliorates acute lung injuries via inhibition of MAP3K2 and MAP3K3
Yuan Q, Basit A, Liang W, Qu R, Luan Y, Ren C, Li A, Xu X, Liu X, Yang C, Kuo A, Pierce R, Zhang L, Turk B, Hu X, Li F, Cui W, Li R, Huang D, Mo L, Sessa WC, Lee PJ, Kluger Y, Su B, Tang W, He J, Wu D. Pazopanib ameliorates acute lung injuries via inhibition of MAP3K2 and MAP3K3. Science Translational Medicine 2021, 13 PMID: 33910977, PMCID: PMC8466683, DOI: 10.1126/scitranslmed.abc2499.Peer-Reviewed Original ResearchConceptsAcute lung injuryLung injuryMyeloid cellsLung transplantation recipientsMouse ALI modelPulmonary barrier functionTransplantation recipientsALI modelReactive oxygen species formationPharmacological interventionsPazopanibOxygen species formationVasculature integrityEpithelial cell survivalHigh mortalityMitogen-activated protein kinase kinase kinase 2Barrier functionGenetic inactivationInjuryCell survivalMortalityProtein kinase kinase kinase 2MAP3K3Kinase 2Manifestations
2020
Association of a Prior Psychiatric Diagnosis With Mortality Among Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Infection
Li L, Li F, Fortunati F, Krystal JH. Association of a Prior Psychiatric Diagnosis With Mortality Among Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Infection. JAMA Network Open 2020, 3: e2023282. PMID: 32997123, PMCID: PMC7527869, DOI: 10.1001/jamanetworkopen.2020.23282.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overBetacoronavirusCerebrovascular DisordersCohort StudiesComorbidityCoronavirus InfectionsCOVID-19Diabetes MellitusFemaleHeart FailureHIV InfectionsHospitalizationHumansKaplan-Meier EstimateKidney DiseasesLiver DiseasesMaleMental DisordersMiddle AgedMyocardial InfarctionNeoplasmsPandemicsPneumonia, ViralProportional Hazards ModelsRisk FactorsSARS-CoV-2United StatesTransdisciplinary Research in Energetics and Cancer early career investigator training program: first year results
Irwin ML, Lowry D, Neuhouser ML, Ligibel J, Schmitz K, Patterson RE, Colditz G, Li F, Nebeling L. Transdisciplinary Research in Energetics and Cancer early career investigator training program: first year results. Translational Behavioral Medicine 2020, 11: 549-562. PMID: 32065834, PMCID: PMC7963289, DOI: 10.1093/tbm/ibaa009.Peer-Reviewed Original ResearchConceptsYear of mentorshipYear 1 participantsEarly career investigatorsCancer burdenCancer riskHealth of populationsMentorship periodTraining programProgram satisfactionGroup sessionsCancer researchSmall group sessionsYear resultsFirst year resultsRiskEnergy imbalanceProgram impactFifth yearCourseInvestigatorsSessionsFellowsYearsCancerMortality