Emily Christison-Lagay, MD
Cards
About
Titles
Associate Professor of Surgery (Pediatrics)
Director of Pediatric Trauma, Surgery; Surgical Director, Pediatric Thyroid Center, Surgery
Biography
Emily Christison-Lagay, MD is a pediatric surgeon with broad clinical interests spanning the width pediatric surgery from congenital anomalies in newborns to common childhood surgical conditions (hernias, appendicitis, gallbladder disease) to childhood tumors, trauma, and benign and malignant thyroid disease. She is the surgical director of the Pediatric Thyroid Center at Yale and the Director of Pediatric Trauma. Following completion of her pediatric surgical training, Dr. Christison-Lagay pursued additional training in the medical and surgical management of pediatric solid tumors including thoracic, liver, and renal tumors, as well as neuroblastoma, childhood sarcomas, and pediatric diseases of the thyroid. She is board-certified in surgery and pediatric surgery,
Dr. Christison-Lagay completed her medical degree at Harvard Medical School and her general surgical residency at the Massachusetts General Hospital, with research in tumor angiogenesis at Boston Children's Hospital. From there, she completed a pediatric surgical fellowship at the Hospital for Sick Children in Toronto, followed by a "super"-fellowship in pediatric surgical oncology at Memorial Sloan Kettering Cancer Center. She is a member of the Children's Oncology Group and the International Society of Paediatric Surgical Oncology as well the American Thyroid Association Taskforce on Pediatric Thyroid Disease and a founding member of the Child and Adolescent Thyroid Consortium.
Appointments
Pediatric Surgery
Associate Professor on TermPrimaryPediatrics
Associate Professor on TermSecondary
Other Departments & Organizations
- All Institutions
- Fetal Care Center
- General Pediatric & Thoracic Surgery
- Pediatric Aerodigestive Disorders Program
- Pediatric Inflammatory Bowel Disease Surgery Program
- Pediatric Surgery
- Pediatric Surgery
- Pediatric Trauma Surgery Program
- Pediatrics
- Surgery
- Yale Medicine
- Yale New Haven Health System
- Yale Ventures
Education & Training
- Fellowship
- Memorial Sloan Kettering Cancer Center (2012)
- Fellowship
- Hospital for Sick Children (2011)
- Residency
- Massachusetts General Hospital (2009)
- Fellowship
- Massachusetts General Hospital (2009)
- MD
- Harvard Medical School (2002)
Research
Publications
2026
Variation in Management of Blunt Splenic Injury by Trauma Center Training Status.
Hellmann Z, Sohi G, Thaxton C, Jones A, Christison-Lagay E, Solomon D. Variation in Management of Blunt Splenic Injury by Trauma Center Training Status. Journal Of The American College Of Surgeons 2026 PMID: 41562442, DOI: 10.1097/xcs.0000000000001779.Peer-Reviewed Original ResearchBlunt splenic injuryNon-operative managementManagement of blunt splenic injuryPediatric Health Information SystemSplenic injuryInjury Severity ScoreSurgical managementPatient demographicsNon-operative management of blunt splenic injuryFailure of non-operative managementPediatric blunt splenic injuryPercutaneous endovascular embolizationSevere splenic injuriesPediatric trauma surgeonICD-10 diagnostic codesHealth information systemsInjury severityMultivariate logistic regressionRates of interventionSplenic interventionEndovascular embolizationFellowship training programsSurgical fellowshipsSurgical interventionInterinstitutional variabilityImplementing an Education Intervention for Prescription Opioid Pain Medication at Pediatric Trauma Centers
Mello M, Baird J, Spirito A, Scott K, Zonfrillo M, Lee L, Kiragu A, Christison-Lagay E, Bromberg J, Ruest S, Pruitt C, Lawson K, Nasr I, Aidlen J, Becker S. Implementing an Education Intervention for Prescription Opioid Pain Medication at Pediatric Trauma Centers. Substance Use & Misuse 2026, ahead-of-print: 1-6. PMID: 41481074, DOI: 10.1080/10826084.2025.2609292.Peer-Reviewed Original ResearchOpioid pain medicationsPediatric trauma centerMedical educationPain medicationTrauma centerEducational interventionOpioid prescribingOpioid pain medication useAdolescent patientsPrescription opioid pain medicationPreventive educational interventionsPain medication useIntervention implementationOpioid overdose deathsPost-implementationPositive screenPain managementMedication useTrained staffHospital dischargeOpioidInterventionOverdose deathsFamily membersMedicationMulticenter Histology Image Integration and Multiscale Deep Learning Support Machine Learning-Enabled Pediatric Sarcoma Classification.
Thiesen A, Domanskyi S, Foroughi Pour A, Zhang J, Sheridan T, Neuhauser S, Stetson A, Dannheim K, Henriksen J, Cameron D, Ahn S, Wu H, Christison Lagay E, Bult C, Chen E, Chuang J, Rubinstein J. Multicenter Histology Image Integration and Multiscale Deep Learning Support Machine Learning-Enabled Pediatric Sarcoma Classification. Cancer Research 2026 PMID: 41481196, PMCID: PMC12893192, DOI: 10.1158/0008-5472.can-25-2275.Peer-Reviewed Original ResearchConvolutional neural networkWhole slide imagesMultiple convolutional neural networksTransformer encoder architectureTwo-stage pipelineDeep learning methodsEncoder architectureFeature extractorVision TransformerImage harmonizationClassifier generalizabilityClassification accuracyNeural networkMultiscale featuresLearning methodsDigital histopathologySlide imagesClassifierArchitectureClassificationRepresentationImagesGPUPipelineExtractor
2025
Factors Associated With Rare Pediatric Cancer Trial Enrollment: A Report From the Children's Oncology Group Rare Tumors Committee
Englum B, Piao J, Younis L, Baertschiger R, Chen K, Christison‐Lagay E, Dholaria H, Gartrell R, Hicks M, Kamihara J, Mitchell S, Orjuela‐Grimm M, Pashankar F, Potter S, Aldrink J, Rosenblum J, Sargen M, Schultz K, Seynnaeve B, Wedekind M, Laetsch T. Factors Associated With Rare Pediatric Cancer Trial Enrollment: A Report From the Children's Oncology Group Rare Tumors Committee. Pediatric Blood & Cancer 2025, 73: e32164. PMID: 41451685, PMCID: PMC13034881, DOI: 10.1002/pbc.32164.Peer-Reviewed Original ResearchConceptsChildren's Oncology GroupRare cancersTherapeutic trialsAdrenocortical carcinomaNasopharyngeal carcinomaBiobank studyChildren's Oncology Group studyPatient geographyUS childrenTrial accrualUS populationRare Tumor CommitteeUS incidenceEnd ResultsPatient characteristicsDemographic dataTumor CommitteeUS patientsOncology GroupThyroid carcinomaEnrollmentMolecular testingTrial developmentCarcinomaCancerComparing injury severity scores from trauma registries with those mapped from injury diagnosis codes in injured adolescents
Zonfrillo M, Baird J, Spirito A, Scott K, Lee L, Kiragu A, Christison-Lagay E, Bromberg J, Ruest S, Pruitt C, Lawson K, Nasr I, Aidlen J, Maxson R, Becker S, Mello M. Comparing injury severity scores from trauma registries with those mapped from injury diagnosis codes in injured adolescents. Injury Prevention 2025, 32: 348-351. PMID: 41386800, DOI: 10.1136/ip-2024-045525.Peer-Reviewed Original ResearchInjury Severity ScoreTrauma registryAbbreviated Injury ScaleInternational ClassificationInternational Classification of Diseases (ICD)Electronic health recordsInjury diagnosis codePaediatric trauma centreAbbreviated Injury Scale scoreAdolescent trauma patientsSeverity scoreHealth recordsInjury Severity Score valuesInjury severity classificationClinical careDiagnosis codesTrauma centreQuality improvementICD-10Injury ScaleRegistryISS valuesInjury severityDescriptive analysisTrauma patientsManagement of perianal abscesses in infants: A systematic review from the APSA outcomes and evidence-based practice committee
Acker S, Sulkowski J, Chang H, Cyrus J, Christison-Lagay E, Mansfield S, Diesen D, Gulack B, Russell K, Beres A, Rentea R, Yousef Y, Alemayehu H, Danko M, Kabagambe S, Kulaylat A, Levene T, Pennell C, Polites S, Ramjist J, Rich B, Scholz S, Skarda D, Tashiro J, Hey M, Ignacio R, Baird R, Kelley-Quon L, Ricca R, Committee T. Management of perianal abscesses in infants: A systematic review from the APSA outcomes and evidence-based practice committee. Journal Of Pediatric Surgery 2025, 60: 162691. PMID: 40983150, DOI: 10.1016/j.jpedsurg.2025.162691.Peer-Reviewed Original ResearchConceptsFistula-in-anoManagement of perianal abscessNon-operative approachNonoperative managementPerianal abscessPerianal diseaseAmerican Pediatric Surgical Association OutcomesManagement of fistula-in-anoFailure of nonoperative managementSystematic reviewPractice CommitteeRecurrence rateSurgical managementTreatment strategiesAbscessOperative interventionApproaches to managementPreferred Reporting ItemsConsensus-based questionsComprehensive search strategyRecurrenceCase-by-case basisReporting ItemsInfantsAssociated outcomesArnold Schwarzenegger or Danny DeVito? The fate of twins with necrotizing enterocolitis in the NICU
Hellmann Z, Thaxton C, Sapir N, Rehman S, Cowles R, Christison-Lagay E, Solomon D. Arnold Schwarzenegger or Danny DeVito? The fate of twins with necrotizing enterocolitis in the NICU. Journal Of Pediatric Surgery 2025, 61: 162526. PMID: 40812408, DOI: 10.1016/j.jpedsurg.2025.162526.Peer-Reviewed Original ResearchMultiple gestation pregnanciesGestation pregnanciesSingleton birthsUncontrolled cohortIncidence of necrotizing enterocolitisNeonatal intensive care unitDevelopment of NECIncidence of NECPediatric Health Information SystemIntensive care unitSingleton gestationsGestational ageMultiple gestationsNICU populationSingleton infantsNecrotizing enterocolitisNICU infantsLow birthweightAverage birthweightInternal validityPrimary outcomeGestationCare unitShort gestationInfantsWhy did the children cross the road? The relationship between roadway design and severe pediatric trauma in pedestrians struck by motor vehicle
Hellmann Z, Jones A, Thaxton C, Bergus K, Mansfield A, Solomon D, Mansfield S, Christison-Lagay E. Why did the children cross the road? The relationship between roadway design and severe pediatric trauma in pedestrians struck by motor vehicle. Journal Of Pediatric Surgery 2025, 61: 162522. PMID: 40812397, DOI: 10.1016/j.jpedsurg.2025.162522.Peer-Reviewed Original ResearchInjury Severity ScorePediatric pedestriansSchool zonesIntersection densityMotor vehiclesICD-10 diagnostic codesRoadway designMultivariable Poisson regressionLower Injury Severity ScoreWalking IndexSevere pediatric traumaOhio DepartmentSeverity of injuryPoisson regressionDiagnostic codesCensus tractsPediatric traumaICD-10Children's HospitalPediatric hospitalPrimary outcomeSlow trafficSpeed limitDriving speedSeverity scoreRelationship Between Total Parenteral Nutrition, Ventilation, and Hepatoblastoma: A Study of 258,929 Neonatal Intensive Care Unit Admissions
Hellmann Z, Rehman S, Brown L, Vasquez J, Solomon D, Christison‐Lagay E. Relationship Between Total Parenteral Nutrition, Ventilation, and Hepatoblastoma: A Study of 258,929 Neonatal Intensive Care Unit Admissions. Pediatric Blood & Cancer 2025, 72: e31741. PMID: 40275525, PMCID: PMC12209882, DOI: 10.1002/pbc.31741.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitPediatric Health Information SystemNeonatal intensive care unit admissionDays of TPNDiagnosis of hepatoblastomaMechanical ventilationGestational ageBirth weightNeonatal intensive care unit hospitalizationPediatric Health Information System hospitalsNICU interventionsDuration of TPNIntensive care unit admissionTotal parenteral nutritionLow birth weightDevelopment of hepatoblastomaIntensive care unitConditional logistic regressionParenteral nutritionUnit admissionClinical characteristicsHepatoblastomaOvergrowth syndromeVentilation exposureCare unitThe Natural History of Congenital Hepatic Hemangiomas
Ostertag-Hill C, Fevurly R, Kulungowski A, Christison-Lagay E, McGuire A, Rialon K, Duggan E, Murillo R, Zurakowski D, Staffa S, Alomari A, Kozakewich H, Al-Ibraheemi A, Fishman S, Dickie B. The Natural History of Congenital Hepatic Hemangiomas. The Journal Of Pediatrics 2025, 281: 114523. PMID: 40023218, DOI: 10.1016/j.jpeds.2025.114523.Peer-Reviewed Original ResearchCongenital hepatic hemangiomasCongenital HHHepatic hemangiomaMedical therapyRetrospective review of patientsNatural historyReview of patientsKaplan-Meier curvesMonths of ageCongenital hemangiomaRetrospective reviewClinical presentationRespiratory failureClinical behaviorHeart failureHH volumeHistological findingsEarly recognitionResidual volumeGeneralized Estimating EquationsIncorrect diagnosisHemangiomaPatientsNo differenceRate of involution
Clinical Care
Overview
Emily Christison-Lagay, MD, is a pediatric surgeon with broad clinical interests spanning the width of pediatric surgery from congenital anomalies in newborns to common childhood surgical conditions (hernias, appendicitis, gallbladder disease) to childhood tumors, trauma, and benign and malignant thyroid disease. She is board-certified in surgery and pediatric surgery and has pursued additional training in the medical and surgical management of pediatric solid tumors including thoracic, liver, and renal tumors, as well as neuroblastoma, childhood sarcomas, and pediatric diseases of the thyroid.
She completed her medical degree at Harvard Medical School and her general surgical residency at the Massachusetts General Hospital, with research in tumor angiogenesis at Boston Children's Hospital. From there, she completed a pediatric surgical fellowship at the Hospital for Sick Children in Toronto, followed by a "super" fellowship in pediatric surgical oncology at Memorial Sloan Kettering Cancer Center. She is a member of both the Children's Oncology Group and the American Thyroid Association Taskforce on Pediatric Thyroid Disease.
Clinical Specialties
Fact Sheets
Pediatric Crohn's Disease
Learn More on Yale MedicinePediatric Ulcerative Colitis
Learn More on Yale MedicinePediatric Congenital Heart Surgery
Learn More on Yale MedicinePediatric Cancer Surgery
Learn More on Yale Medicine
Yale Medicine News
News & Links
News
Get In Touch
Contacts
Pediatric Surgery
PO Box 208062
New Haven, CT 06520-8062
United States
Administrative Support
Locations
Patient Care Locations
Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.