2022
Hypothalamic connectivities predict individual differences in ADT-elicited changes in working memory and quality of life in prostate cancer patients
Chaudhary S, Roy A, Summers C, Zhornitsky S, Ahles T, Li CR, Chao HH. Hypothalamic connectivities predict individual differences in ADT-elicited changes in working memory and quality of life in prostate cancer patients. Scientific Reports 2022, 12: 9567. PMID: 35688928, PMCID: PMC9187668, DOI: 10.1038/s41598-022-13361-4.Peer-Reviewed Original ResearchMeSH KeywordsAndrogen AntagonistsAndrogensHumansHypothalamusIndividualityMaleMemory, Short-TermProstatic NeoplasmsQuality of LifeConceptsAndrogen deprivation therapyProstate cancer patientsQuality of lifeCancer patientsCorrect response rateMonths of ADTLong-term androgen deprivation therapyResponse rateNon-metastatic prostate cancerMontreal Cognitive Assessment scoreProspective observational studyState functional connectivityCognitive Assessment scoreDeprivation therapyHypothalamic connectivityAndrogen deprivationPrognostic markerProstate cancerGonadal axisObservational studyYears of educationQOL effectsControl groupQoLSalience networkAcute effects of ketamine and esketamine on cognition in healthy subjects: A meta-analysis
Zhornitsky S, Tourjman V, Pelletier J, Assaf R, Li CR, Potvin S. Acute effects of ketamine and esketamine on cognition in healthy subjects: A meta-analysis. Progress In Neuro-Psychopharmacology And Biological Psychiatry 2022, 118: 110575. PMID: 35568275, DOI: 10.1016/j.pnpbp.2022.110575.Peer-Reviewed Original ResearchMeSH KeywordsCognitionCognition DisordersHealthy VolunteersHumansKetamineMemory, Short-TermNeuropsychological TestsConceptsVerbal learningCognitive domainsResponse inhibitionAcute ketamine administrationVerbal learning/memorySpeed of processingLearning/memorySocial cognitionVerbal memoryExecutive functionVisual learningVisuospatial abilitiesMemory figuresCognitionMemoryCognitive impairmentAcute ketamineKetamine administrationEffect sizeLearningImpairmentModerate impairmentDeficitsNegative effectsHealthy individualsThe effects of androgen deprivation on working memory and quality of life in prostate cancer patients: The roles of hypothalamic connectivity
Chaudhary S, Zhornitsky S, Roy A, Summers C, Ahles T, Li C, Chao HH. The effects of androgen deprivation on working memory and quality of life in prostate cancer patients: The roles of hypothalamic connectivity. Cancer Medicine 2022, 11: 3425-3436. PMID: 35315585, PMCID: PMC9487881, DOI: 10.1002/cam4.4704.Peer-Reviewed Original ResearchMeSH KeywordsAndrogen AntagonistsAndrogensHumansHypothalamusMaleMemory, Short-TermProstatic NeoplasmsQuality of LifeTestosteroneConceptsAndrogen deprivation therapyMid-cingulate cortexEffects of ADTFunctional connectivityPrecentral gyrusN-back taskN-back performanceState functional connectivityMontreal Cognitive Assessment scoreHypothalamic functional connectivityProspective observational studyNonmetastatic prostate cancerProstate cancer patientsCognitive Assessment scoreQuality of lifeSustain attentionAffective functionsDeprivation therapyHypothalamic connectivityYears of educationAndrogen deprivationCorrect response rateQOL scoresCancer patientsClinical correlatesClinical and behavior characteristics of individuals who used ketamine
Lee TS, Liu YH, Huang YJ, Tang WK, Wang Y, Hu S, Lin CP, Li CR, Hung CC. Clinical and behavior characteristics of individuals who used ketamine. Scientific Reports 2022, 12: 801. PMID: 35039593, PMCID: PMC8764021, DOI: 10.1038/s41598-022-04832-9.Peer-Reviewed Original ResearchConceptsMemory testLower urinary tract symptomsN-back memory testShort-term recallShort-term memoryDrug-using participantsCigarette smokersImpulsivity measuresTerm recallBehavioral dispositionsPolydrug usersKetamine usersGroup of individualsSex-related behaviorsUrinary tract symptomsPolydrug useDrug-related problemsCross-sectional interviewMemoryRisk behaviorsKetamine useTract symptomsClinical characteristicsParticipantsHIV serostatusDo Real-Time Strategy Video Gamers Have Better Attentional Control?
He M, Xu LX, Li CR, Liu Z, Hu J, Guo X, Liu H, Zhang JT. Do Real-Time Strategy Video Gamers Have Better Attentional Control? Human Factors The Journal Of The Human Factors And Ergonomics Society 2022, 66: 258-270. PMID: 35012373, DOI: 10.1177/00187208211064683.Peer-Reviewed Original ResearchConceptsNon-video game playersStreet-crossing taskBetter attentional controlAttentional controlReal-life tasksMulti-object tracking taskVideo gamersMOT taskSecondary taskSensory modalitiesAuditory secondary taskVisual dual taskAction video gamesMultiple visual objectsGame playersVideo game experienceVideo game playersVideo gamesAttentional advantageMemory taskAuditory taskVisual objectsDual taskVR taskVirtual reality environment
2021
Neural correlates of individual variation in two-back working memory and the relationship with fluid intelligence
Li G, Chen Y, Le TM, Wang W, Tang X, Li CR. Neural correlates of individual variation in two-back working memory and the relationship with fluid intelligence. Scientific Reports 2021, 11: 9980. PMID: 33976306, PMCID: PMC8113462, DOI: 10.1038/s41598-021-89433-8.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainFemaleHumansIntelligenceMagnetic Resonance ImagingMaleMemory, Short-TermReaction TimeYoung AdultConceptsDorsal anterior cingulate cortexN-back performanceRight anterior insulaStandard Progressive Matrices testFluid intelligenceNeural correlatesReaction timePre-supplementary motor areaRaven's Standard Progressive Matrices testN-back taskIndividual variationHuman Connectome Project datasetProgressive Matrices TestProlonged response timeBilateral frontoparietal cortexAnterior cingulate cortexTwo-backNeural basisDorsal precuneusRSPM performanceNeural processesNeural substratesAnterior insulaCerebral correlatesCorrect items
2020
Acute effects of partial CB1 receptor agonists on cognition – A meta-analysis of human studies
Zhornitsky S, Pelletier J, Assaf R, Giroux S, Li CR, Potvin S. Acute effects of partial CB1 receptor agonists on cognition – A meta-analysis of human studies. Progress In Neuro-Psychopharmacology And Biological Psychiatry 2020, 104: 110063. PMID: 32791166, DOI: 10.1016/j.pnpbp.2020.110063.Peer-Reviewed Original ResearchMeSH KeywordsAttentionCannabinoid Receptor AgonistsCognitionExecutive FunctionHumansMemory, Short-TermNeuropsychological TestsConceptsVerbal learning/memorySpeed of processingLearning/memoryCognitive domainsResidual cognitive effectsChronic cannabis usersAcute cannabis consumptionExecutive functionCognitive effectsCannabis usersImpulsivityEffect size estimatesMemoryCognitive dysfunctionCannabis consumptionCognitionCB1 receptor agonistDeficitsModerate impairmentProcessingAnalysis of routesImpairmentIntravenous administration studyComprehensive Meta-AnalysisNegative effects
2019
Elevated serum anti-NMDA receptor antibody levels in first-episode patients with schizophrenia
Tong J, Huang J, Luo X, Chen S, Cui Y, An H, Xiu M, Tan S, Wang Z, Yuan Y, Zhang J, Yang F, Li CR, Hong L, Tan Y. Elevated serum anti-NMDA receptor antibody levels in first-episode patients with schizophrenia. Brain Behavior And Immunity 2019, 81: 213-219. PMID: 31201848, PMCID: PMC6754783, DOI: 10.1016/j.bbi.2019.06.017.Peer-Reviewed Original ResearchConceptsN-methyl-D-aspartate (NMDA) glutamate receptorsFirst-episode patientsNMDAR antibodiesAntibody levelsHealthy controlsSerum anti-NMDAR antibodyTotal scoreAnti-NMDAR antibodiesNMDAR antibody levelsNMDAR-antibody encephalitisElevated levelsReceptor antibody levelsSerum antibody levelsTreatment of schizophreniaPathogenesis of schizophreniaNegative Syndrome ScaleSymptoms of psychosisEnzyme-linked immunosorbentEtiology of schizophreniaMCCB total scoreAntibody encephalitisPatient groupNMDAR dysfunctionSchizophrenia (MATRICS) Consensus Cognitive BatteryGlutamate receptors