2015
Number of Drinks to “Feel a Buzz” by HIV Status and Viral Load in Men
McGinnis KA, Fiellin DA, Tate JP, Cook RL, Braithwaite RS, Bryant KJ, Edelman EJ, Gordon AJ, Kraemer KL, Maisto SA, Justice AC, The Veterans Aging Cohort Study. Number of Drinks to “Feel a Buzz” by HIV Status and Viral Load in Men. AIDS And Behavior 2015, 20: 504-511. PMID: 26936030, PMCID: PMC4780364, DOI: 10.1007/s10461-015-1053-7.Peer-Reviewed Original ResearchConceptsUninfected menNumber of drinksViral load suppressionMean numberImpact of HIVBlood alcohol concentrationEffects of alcoholAntiretroviral initiationDetectable VLCohort studyVL suppressionHIV statusMultivariable analysisViral loadLower mean numberHIVCurrent drinkingMenDrinksAlcohol concentrationSuppressionAlcohol-Related Diagnoses and All-Cause Hospitalization Among HIV-Infected and Uninfected Patients: A Longitudinal Analysis of United States Veterans from 1997 to 2011
Rentsch C, Tate JP, Akgün KM, Crystal S, Wang KH, Ryan Greysen S, Wang EA, Bryant KJ, Fiellin DA, Justice AC, Rimland D. Alcohol-Related Diagnoses and All-Cause Hospitalization Among HIV-Infected and Uninfected Patients: A Longitudinal Analysis of United States Veterans from 1997 to 2011. AIDS And Behavior 2015, 20: 555-564. PMID: 25711299, PMCID: PMC4550577, DOI: 10.1007/s10461-015-1025-y.Peer-Reviewed Original ResearchConceptsAlcohol-related diagnosesHospitalization ratesUnited States veteransUninfected patientsCause hospitalizationHIV infectionStates veteransUninfected individualsMultivariable Cox proportional hazards modelsCox proportional hazards modelOverall hospitalization rateProportional hazards modelCancer admissionsAntiretroviral therapyMultivariable adjustmentHIV serostatusComorbidity variablesHospitalization trendsRelative riskHigh riskHazards modelHIVHospitalizationDisease categoriesPatients
2014
Increased Risk of Radiographic Emphysema in HIV Is Associated With Elevated Soluble CD14 and Nadir CD4
Attia EF, Akgün KM, Wongtrakool C, Goetz MB, Rodriguez-Barradas MC, Rimland D, Brown ST, Hoo G, Kim J, Lee PJ, Schnapp LM, Sharafkhaneh A, Justice AC, Crothers K. Increased Risk of Radiographic Emphysema in HIV Is Associated With Elevated Soluble CD14 and Nadir CD4. CHEST Journal 2014, 146: 1543-1553. PMID: 25080158, PMCID: PMC4251616, DOI: 10.1378/chest.14-0543.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsBiomarkersCD4 AntigensComorbidityConfidence IntervalsCross-Sectional StudiesFemaleHIV InfectionsHumansLipopolysaccharide ReceptorsLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPrognosisPulmonary EmphysemaRadiographyReference ValuesRisk AssessmentSensitivity and SpecificitySeverity of Illness IndexSex FactorsStatistics, NonparametricConceptsIndependent risk factorSoluble CD14 levelsHIV infectionRadiographic emphysemaEmphysema severityCD14 levelsRisk factorsHIV-Associated Lung Emphysema (EXHALE) studyHigher soluble CD14 levelsNadir CD4 cell countMultivariable logistic regression modelElevated soluble CD14CD4 cell countCells/μLLower lung zonesRisk of HIVCross-sectional analysisLogistic regression modelsNadir CD4HIV RNALung involvementHIV severityD-dimerDiffuse involvementMultivariable analysis
2013
Agreement Between Electronic Medical Record-based and Self-administered Pain Numeric Rating Scale
Goulet JL, Brandt C, Crystal S, Fiellin DA, Gibert C, Gordon AJ, Kerns RD, Maisto S, Justice AC. Agreement Between Electronic Medical Record-based and Self-administered Pain Numeric Rating Scale. Medical Care 2013, 51: 245-250. PMID: 23222528, PMCID: PMC3572341, DOI: 10.1097/mlr.0b013e318277f1ad.Peer-Reviewed Original ResearchConceptsNumeric rating scaleElectronic medical recordsPain screeningMedical recordsPain numeric rating scaleRating ScaleModerate-severe painVeterans Affairs medical facilitiesPatients' electronic medical recordsMajor depressive disorderEMR dataQuality of careUnderestimation of painSample of veteransPosttraumatic stress disorderHealth care systemClinical characteristicsPatient characteristicsNRS scoresPain careDepressive disorderSurvey scoresPainLevel of agreementStress disorder
2011
Rural Residence and Adoption of a Novel HIV Therapy in a National, Equal-Access Healthcare System
Ohl M, Lund B, Belperio PS, Goetz MB, Rimland D, Richardson K, Justice A, Perencevich E, Vaughan-Sarrazin M. Rural Residence and Adoption of a Novel HIV Therapy in a National, Equal-Access Healthcare System. AIDS And Behavior 2011, 17: 250-259. PMID: 22205324, PMCID: PMC5009625, DOI: 10.1007/s10461-011-0107-8.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedCD4 Lymphocyte CountChildChild, PreschoolDelivery of Health CareDiffusion of InnovationFemaleHealth Services AccessibilityHealthcare DisparitiesHIV InfectionsHIV Integrase InhibitorsHumansInfantInfant, NewbornMaleMiddle AgedMultivariate AnalysisOdds RatioPatient Acceptance of Health CarePyrrolidinonesRaltegravir PotassiumResidence CharacteristicsRetrospective StudiesRural Health ServicesRural PopulationSurveys and QuestionnairesUnited StatesUnited States Department of Veterans AffairsUrban PopulationVeteransViral LoadYoung AdultConceptsHIV therapyEqual access healthcare systemNovel HIV therapiesRetrospective cohort studyFirst HIV integrase inhibitorRural-urban variationRaltegravir therapyCohort studyPatient characteristicsMultivariable analysisHIV integrase inhibitorsClinical indicationsRural residenceFDA approvalTherapyIntegrase inhibitorsUrban residenceRural personsHealthcare systemRaltegravirUrban personsDaysRural areasHIVResidence
2010
Refill Adherence to Oral Hypoglycemic Agents and Glycemic Control in Veterans
Kim N, Agostini JV, Justice AC. Refill Adherence to Oral Hypoglycemic Agents and Glycemic Control in Veterans. Annals Of Pharmacotherapy 2010, 44: 800-808. PMID: 20388863, PMCID: PMC3117591, DOI: 10.1345/aph.1m570.Peer-Reviewed Original ResearchConceptsOral hypoglycemic agentsGlycemic controlGoal A1CHypoglycemic agentsBaseline dateInadequate diabetes controlPercent of patientsPoor glycemic controlMain outcome measuresBaseline A1CContinuous refillNonpersistent patientsComorbid hypertensionDiabetes medicationsMedian ageBetter persistenceMedication nonadherenceDiabetes controlDays' supplyOutcome measuresClinical careEligible veteransPatientsA1CMedications
2008
Quantifying the Decrement in Utility from Perceived Side Effects of Combination Antiretroviral Therapies in Patients with HIV
Braithwaite RS, Goulet J, Kudel I, Tsevat J, Justice AC. Quantifying the Decrement in Utility from Perceived Side Effects of Combination Antiretroviral Therapies in Patients with HIV. Value In Health 2008, 11: 975-979. PMID: 18225989, PMCID: PMC3121315, DOI: 10.1111/j.1524-4733.2007.00315.x.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyBothersome symptomsSF-6D utilitiesAntiretroviral therapyCD4 countSide effectsVeterans Aging Cohort StudyAging Cohort StudySF-12 scoresAfrican American raceHazardous alcohol consumptionQuality of lifeRecent drug useCART initiationMild anginaCohort studyMultivariable analysisCigarette smokingUnivariate analysisAmerican raceAlcohol consumptionDrug useUtility decrementsPatientsClinical decision
2007
Do Patterns of Comorbidity Vary by HIV Status, Age, and HIV Severity?
Goulet JL, Fultz SL, Rimland D, Butt A, Gibert C, Rodriguez-Barradas M, Bryant K, Justice AC. Do Patterns of Comorbidity Vary by HIV Status, Age, and HIV Severity? Clinical Infectious Diseases 2007, 45: 1593-1601. PMID: 18190322, PMCID: PMC3687553, DOI: 10.1086/523577.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusCD4 cell countPatterns of comorbidityHIV infectionHIV statusCell countHIV severityOlder human immunodeficiency virusPrimary care guidelinesClinical Modification codesCells/Pulmonary diseaseComorbid conditionsMultivariable analysisViral loadCare guidelinesImmunodeficiency virusComorbiditiesInternational ClassificationMultimorbidityInfectionPresence of conditionsVeteransAgeDisease
2006
Health‐Related Quality of Life in Veterans and Nonveterans with HIV/AIDS
Mrus JM, Leonard AC, Yi MS, Sherman SN, Fultz SL, Justice AC, Tsevat J. Health‐Related Quality of Life in Veterans and Nonveterans with HIV/AIDS. Journal Of General Internal Medicine 2006, 21: s39-s47. PMID: 17083499, PMCID: PMC1924783, DOI: 10.1111/j.1525-1497.2006.00644.x.Peer-Reviewed Original ResearchConceptsHIV/AIDSSymptom botherDepressive symptomsCorrelates of HRQOLPoorer overall functionDeterminants of HRQoLNon-VA settingsHealth-related qualityInjection drug useRating Scale scoresUnstable housing situationsVeterans Administration settingsQuality of lifeVeteran statusHealth valueOverall functionPoor HRQOLHRQOL outcomesMultivariable analysisHRQOL measuresMultivariable associationsMultivariable modelHRQoLVeteran populationHealth ratingsSpirituality and Religion in Patients with HIV/AIDS
Cotton S, Puchalski CM, Sherman SN, Mrus JM, Peterman AH, Feinberg J, Pargament KI, Justice AC, Leonard AC, Tsevat J. Spirituality and Religion in Patients with HIV/AIDS. Journal Of General Internal Medicine 2006, 21: s5-s13. PMID: 17083501, PMCID: PMC1924778, DOI: 10.1111/j.1525-1497.2006.00642.x.Peer-Reviewed Original ResearchConceptsHIV/AIDSMean ageSpirituality/religionPatients' mean ageLower overall functioningDuke Religion IndexClinical characteristicsMost patientsHIV symptomsChronic illnessLess alcohol useMultivariable modelDepressive symptomsPatientsFunctional assessmentHealth statusClinical sitesLess alcoholAlcohol usePsychosocial variablesIllnessMean levelsAIDSReligion IndexGreater life satisfaction
2004
Risk of diabetes in HIV infected veterans pre‐ and post‐HAART and the role of HCV coinfection
Butt AA, Fultz SL, Kwoh CK, Kelley D, Skanderson M, Justice AC. Risk of diabetes in HIV infected veterans pre‐ and post‐HAART and the role of HCV coinfection. Hepatology 2004, 40: 115-119. PMID: 15239093, DOI: 10.1002/hep.20289.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusPre-HAART eraHAART eraRisk of diabetesHCV coinfectionHCV infectionHigh riskHepatitis C virus infectionMultivariate Cox regression analysisVeterans Affairs administrative databasesActive antiretroviral therapyC virus infectionCox regression analysisIncidence of diabetesKaplan-Meier curvesCox regression methodsDiagnosis of diabetesHCV-HIVAntiretroviral therapyHazard ratioLiver diseaseImmunodeficiency virusAdministrative databasesVirus infectionDrug diagnoses
1998
The Relation Between Health Status Changes and Patient Satisfaction in Older Hospitalized Medical Patients
Covinsky K, Rosenthal G, Chren M, Justice A, Fortinsky R, Palmer R, Landefeld C. The Relation Between Health Status Changes and Patient Satisfaction in Older Hospitalized Medical Patients. Journal Of General Internal Medicine 1998, 13: 223-229. PMID: 9565384, PMCID: PMC1496938, DOI: 10.1046/j.1525-1497.1998.00071.x.Peer-Reviewed Original ResearchConceptsPatient satisfactionMean satisfaction scoreHealth statusMedical patientsHospital careSatisfaction scoresProspective cohort studyOlder medical patientsPatient satisfaction questionnairePatient outcome measuresTendency of patientsGlobal healthHealth status changesHospital outcomesCohort studyGreater satisfactionStable healthHealthy patientsTeaching hospitalOutcome measuresDaily livingPatientsAdmissionMultivariate analysisSimilar satisfaction