Alterations in Volume and Intrinsic Resting-State Functional Connectivity Detected at Brain MRI in Individuals with Opioid Use Disorder.
Mehta S, Peterson H, Ye J, Ibrahim A, Saeed G, Linsky S, Kreinin I, Tsang S, Nwanaji-Enwerem U, Raso A, Arora J, Tokoglu F, Yip S, Hahn C, Lacadie C, Greene A, Jeon S, Constable R, Barry D, Redeker N, Yaggi H, Scheinost D, Weintraub E. Alterations in Volume and Intrinsic Resting-State Functional Connectivity Detected at Brain MRI in Individuals with Opioid Use Disorder. Radiology 2024, 313: e240514. PMID: 39656127, DOI: 10.1148/radiol.240514.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainFemaleHumansMagnetic Resonance ImagingMaleOpioid-Related DisordersYoung AdultConceptsHealthy control participantsRight medial temporal lobeOpioid use disorderFunctional brain alterationsMedial temporal lobeOpioid use disorder groupFunctional connectivityUse disorderControl participantsBrain alterationsIntrinsic resting-state functional connectivityTemporal lobeMedial prefrontal cortex volumesVoxel-wise linear regressionT1-weighted MRIResting-state functional connectivityFamily-wise error correctionPrefrontal cortex volumeResting-state functional MRIIncreased functional connectivityIntrinsic connectivity distributionFunctional MRI studiesFemale participantsRegional brain volumesAssess group differencesMapping the structure-function relationship along macroscale gradients in the human brain
Collins E, Chishti O, Obaid S, McGrath H, King A, Shen X, Arora J, Papademetris X, Constable R, Spencer D, Zaveri H. Mapping the structure-function relationship along macroscale gradients in the human brain. Nature Communications 2024, 15: 7063. PMID: 39152127, PMCID: PMC11329792, DOI: 10.1038/s41467-024-51395-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainBrain MappingCognitionFemaleHumansMagnetic Resonance ImagingMaleMotor CortexNatural Language ProcessingNerve NetStructure-Activity RelationshipWhite MatterConceptsStructure-function correspondenceBrain regionsMacroscale gradientWhite matter connectivityHuman brain regionsStructure-function couplingNeural network propertiesAssociation cortexCognitive functionBridging neuroscienceFunctional coactivationOrganizational axisCortical thicknessHuman brainMotor cortexLanguage processingBrainCortexMotor functionNatural language processingNetwork propertiesMotorNeuroscienceNatural languageData repositories