2004
Regulation of pulmonary fibrosis by chemokine receptor CXCR3
Jiang D, Liang J, Hodge J, Lu B, Zhu Z, Yu S, Fan J, Gao Y, Yin Z, Homer R, Gerard C, Noble PW. Regulation of pulmonary fibrosis by chemokine receptor CXCR3. Journal Of Clinical Investigation 2004, 114: 291-299. PMID: 15254596, PMCID: PMC449741, DOI: 10.1172/jci16861.Peer-Reviewed Original ResearchConceptsCXC chemokine receptor 3Lung NK cellsCXCR3-deficient miceIFN-gamma productionLung injuryIFN-gammaEnhanced fibrosisNK cellsWT miceChemokine receptors CXC chemokine receptor 3Chemokine MIG/CXCL9Endogenous IFN-gamma productionI-TAC/CXCL11IP-10/CXCL10Inflammatory cell recruitmentProgressive interstitial fibrosisChemokine receptor 3Exogenous IFN-gammaExpression of CXCL10MIG/CXCL9CXCR3 deficiencyAdoptive transferPulmonary injuryLymph nodesPulmonary fibrosis
1993
T cell unresponsiveness correlates with quantitative TCR levels in a transgenic model
Homer R, Mamalaki C, Kioussis D, Flavell R. T cell unresponsiveness correlates with quantitative TCR levels in a transgenic model. International Immunology 1993, 5: 1495-1500. PMID: 7906139, DOI: 10.1093/intimm/5.12.1495.Peer-Reviewed Original Research