2025
Potential roles for vitamin D in preventing and treating impulse control disorders, behavioral addictions, and substance use disorders: A scoping review
Jalilian-Khave L, Kitaneh R, Ysrayl B, Borelli A, Funaro M, Potenza M, Angarita G. Potential roles for vitamin D in preventing and treating impulse control disorders, behavioral addictions, and substance use disorders: A scoping review. Addiction Neuroscience 2025, 14: 100190. DOI: 10.1016/j.addicn.2024.100190.Peer-Reviewed Original ResearchImpulse control disordersSubstance use disordersControl disordersBehavioral addictionsTreating impulse control disordersVitamin DClinical studiesAddictive disordersSerotonergic circuitsExposure to vitamin DVitamin D deficiencyVitamin D levelsSymptom presenceDisordersPotential beneficial effectsJoanna Briggs InstituteD deficiencyPotential therapeutic mechanismAddictionD levelsWeb of ScienceTherapeutic mechanismQuality of studiesCochrane LibraryOvid MEDLINE
2024
Compulsivity-related behavioral features of problematic usage of the internet: A scoping review of paradigms, progress, and perspectives
Liu L, Yao Y, Fang X, Xu L, Hu M, Zhang J, Potenza M. Compulsivity-related behavioral features of problematic usage of the internet: A scoping review of paradigms, progress, and perspectives. Journal Of Behavioral Addictions 2024, 13: 429-449. PMID: 38656807, PMCID: PMC11220808, DOI: 10.1556/2006.2024.00023.Peer-Reviewed Original ResearchFour-domain frameworkAttentional biasHabit learningSet-shiftingCognitive flexibilityInternet gaming disorderAddictive disordersNeuropsychological characteristicsGaming disorderCognitive featuresCompulsionTask resultsBehavioral featuresMultidimensional natureDisordersSystematic literature searchSub-typesDeficitsTherapeutic implicationsWeb of ScienceLearningUmbrella termPsycINFOLiterature searchBiasIntrinsic connectivity demonstrates a shared role of the posterior cingulate for cue reactivity in both gambling and cocaine use disorders
Vaccaro A, Lacadie C, Potenza M. Intrinsic connectivity demonstrates a shared role of the posterior cingulate for cue reactivity in both gambling and cocaine use disorders. Addictive Behaviors 2024, 155: 108027. PMID: 38581751, PMCID: PMC11273263, DOI: 10.1016/j.addbeh.2024.108027.Peer-Reviewed Original ResearchConceptsCocaine use disorderPosterior cingulate cortexCue reactivityBehavioral addictionsUse disorderGambling disorderPosterior cingulatePosterior cingulate cortex connectivityHealthy comparison subjectsIntrinsic connectivity distributionIntervention developmentCocaine cuesFMRI taskAddictive disordersCingulate cortexComparison subjectsNeurobiological foundationsSad videosDecreased connectivityFunctional connectivityCocainePost hoc analysisAddictionRelevant to maintenanceGamblingParameter Space and Potential for Biomarker Development in 25 Years of fMRI Drug Cue Reactivity
Network A, Sangchooli A, Zare-Bidoky M, Jouzdani A, Schacht J, Bjork J, Claus E, Prisciandaro J, Wilson S, Wüstenberg T, Potvin S, Ahmadi P, Bach P, Baldacchino A, Beck A, Brady K, Brewer J, Childress A, Courtney K, Ebrahimi M, Filbey F, Garavan H, Ghahremani D, Goldstein R, Goudriaan A, Grodin E, Hanlon C, Haugg A, Heilig M, Heinz A, Holczer A, Van Holst R, Joseph J, Juliano A, Kaufman M, Kiefer F, Zonoozi A, Kuplicki R, Leyton M, London E, Mackey S, McClernon F, Mellick W, Morley K, Noori H, Oghabian M, Oliver J, Owens M, Paulus M, Perini I, Rafei P, Ray L, Sinha R, Smolka M, Soleimani G, Spanagel R, Steele V, Tapert S, Vollstädt-Klein S, Wetherill R, Witkiewitz K, Yuan K, Zhang X, Verdejo-Garcia A, Potenza M, Janes A, Kober H, Zilverstand A, Ekhtiari H. Parameter Space and Potential for Biomarker Development in 25 Years of fMRI Drug Cue Reactivity. JAMA Psychiatry 2024, 81: 414-425. PMID: 38324323, PMCID: PMC11304510, DOI: 10.1001/jamapsychiatry.2023.5483.Peer-Reviewed Original ResearchTreatment developmentNeurobiology of drug addictionDrug cue reactivitySubstance use disordersBiomarkers of addictionCue reactivityAddictive disordersBiomarker developmentDrug addictionTreatment responseTreatment outcomesVisual cuesTask designCore aspectsAddictionClinical judgmentParticipant characteristicsDisordersOutcome predictorsClinical useMEDLINE databaseBiomarker qualificationSeveral biomarkersTranslational gapDatabase inception
2023
Neural mechanisms linked to treatment outcomes and recovery in substance-related and addictive disorders
Mestre-Bach G, Potenza M. Neural mechanisms linked to treatment outcomes and recovery in substance-related and addictive disorders. Dialogues In Clinical Neuroscience 2023, 25: 75-91. PMID: 37594217, PMCID: PMC10444012, DOI: 10.1080/19585969.2023.2242359.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsNeural mechanismsAddictive disordersPotential neural mechanismsTreatment development effortsInternet gaming disorderBrain processesSubstance use disordersAdvanced analytic approachesGaming disorderImpulse controlTreatment developmentUse disordersPsychiatric conditionsExtant dataTreatment utilityAddictionDisordersAnalytic approachTreatment outcomesNarrative reviewIntervention administrationMedication challengePresent reviewMain modelsContextClinical Correlates of Sports Betting: A Systematic Review
Valenciano-Mendoza E, Mora-Maltas B, Mestre-Bach G, Munguía L, Richard J, Derevensky J, Potenza M, Jiménez-Murcia S. Clinical Correlates of Sports Betting: A Systematic Review. Journal Of Gambling Studies 2023, 39: 579-624. PMID: 37004597, PMCID: PMC10066997, DOI: 10.1007/s10899-023-10196-0.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSystematic reviewMultiple sociodemographic variablesGambling disorderNCBI/PubMedSelf-administered instrumentAPA PsycINFO databasesClinical correlatesCo-occurring psychopathologyGeneral populationPRISMA guidelinesPrevention strategiesClinical diagnosisPsycINFO databasesSubstance useSociodemographic variablesAddictive disordersRelevant studiesVulnerable individualsHigh impulsivityDisordersCertain pathologiesImpulsive malesGambling-related variablesAddictive behaviorsGroups of participantsTransdiagnostic Connectome-Based Prediction of Craving
Garrison K, Sinha R, Potenza M, Gao S, Liang Q, Lacadie C, Scheinost D. Transdiagnostic Connectome-Based Prediction of Craving. American Journal Of Psychiatry 2023, 180: 445-453. PMID: 36987598, DOI: 10.1176/appi.ajp.21121207.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelingImagery conditionFunctional connectomeSelf-reported cravingStudy of motivationDefault mode networkFunctional connectivity dataIndependent samplesKey phenomenological featuresNeural signaturesTransdiagnostic sampleTransdiagnostic perspectiveMode networkMotivated behaviorCentral constructAddictive disordersHuman behaviorConnectivity dataPhenomenological featuresStrongest predictorCravingTaskSubstance use-related disordersConnectomeIndividualsDo attention-deficit/hyperactivity symptoms influence treatment outcome in gambling disorder?
Vintró-Alcaraz C, Mestre-Bach G, Granero R, Gómez-Peña M, Moragas L, Fernández-Aranda F, Potenza M, Jiménez-Murcia S. Do attention-deficit/hyperactivity symptoms influence treatment outcome in gambling disorder? European Psychiatry 2023, 66: s58-s59. PMCID: PMC10417907, DOI: 10.1192/j.eurpsy.2023.212.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderCognitive behavioral therapyADHD symptomsGambling disorderGD severityMeasures of ADHDSelf-reported ADHD symptomsAttention-deficit/hyperactivity symptomsPsychological treatment outcomesDeficit hyperactivity disorderSelf-report instrumentTreatment outcome measuresHyperactivity disorderHyperactivity symptomsBehavioral therapyConnecticut CouncilProblem gamblingPersonality featuresAddictive disordersHigher psychopathologyLongitudinal studyTreatment outcomesPsychopathologyLack of researchSevere relapseRelationship between Signals Regulating Energy Homeostasis and Neuropsychological and Clinical Features in Gambling Disorder: A Case-Control Study
Fernandez-Aranda F, Baenas I, Etxandi M, Mora-Maltas B, Granero R, Tovar S, Diéguez C, Potenza M, Jiménez-Murcia S. Relationship between Signals Regulating Energy Homeostasis and Neuropsychological and Clinical Features in Gambling Disorder: A Case-Control Study. European Psychiatry 2023, 66: s328-s328. PMCID: PMC10434526, DOI: 10.1192/j.eurpsy.2023.722.Peer-Reviewed Original ResearchGambling disorderSemi-structured clinical interviewHigher impulsivity levelsBad psychological stateDysfunctional personality profileDisclosure of interestHigher cognitive impairmentGd presenceCognitive flexibilityBody mass indexNeuropsychological factorsSubstance use disordersDecision-making strategiesHealthy controlsCognitive dimensionsImpulsivity levelsPsychological statePsychometric batteryConnecticut CouncilProblem gamblingVulnerability pathwaysAddictive disordersPersonality profilesCognitive impairmentClinical Interview
2021
Neurobiology of Addiction
Gogliettino A, Potenza M, Yip S, Zakiniaeiz Y, Zhai Z. Neurobiology of Addiction. DeckerMed Medical Cannabis 2021 DOI: 10.2310/cannabis.13044.ChaptersFunctional magnetic resonance imagingBrain functionCo-occurring disordersCognitive aspectsGambling disorderBehavioral addictionsCognitive functionAddictive disordersSubstance addictionDSM-5Substance useNegative consequencesNeurochemical systemsNegative healthVisual representationAddictionSocial consequencesExtant literatureNeurobiologyDisordersCurrent treatment strategiesQuality of lifeMagnetic resonance imagingPositron emission tomographyGamblingNeurobiology of Addiction
Gogliettino A, Potenza M, Yip S, Zakiniaeiz Y, Zhai Z. Neurobiology of Addiction. DeckerMed Psychiatry 2021 DOI: 10.2310/psych.13044.ChaptersFunctional magnetic resonance imagingBrain functionCo-occurring disordersCognitive aspectsGambling disorderBehavioral addictionsCognitive functionAddictive disordersSubstance addictionDSM-5Substance useNegative consequencesNeurochemical systemsNegative healthVisual representationAddictionSocial consequencesExtant literatureNeurobiologyDisordersCurrent treatment strategiesQuality of lifeMagnetic resonance imagingPositron emission tomographyGambling
2019
Epidemiological Challenges in the Study of Behavioral Addictions: a Call for High Standard Methodologies
Rumpf H, Brandt D, Demetrovics Z, Billieux J, Carragher N, Brand M, Bowden-Jones H, Rahimi-Movaghar A, Assanangkornchai S, Glavak-Tkalic R, Borges G, Lee H, Rehbein F, Fineberg N, Mann K, Potenza M, Stein D, Higuchi S, King D, Saunders J, Poznyak V. Epidemiological Challenges in the Study of Behavioral Addictions: a Call for High Standard Methodologies. Current Addiction Reports 2019, 6: 331-337. DOI: 10.1007/s40429-019-00262-2.Peer-Reviewed Original ResearchEpidemiological researchPublic health recommendationsStandardized diagnostic interviewPurpose of ReviewThePutative behavioral addictionsBehavioral addictionsHealth recommendationsDiagnostic criteriaEpidemiological studiesInternational ClassificationDiagnostic InterviewMental disordersSummaryThis reviewEvidence baseSound assessment toolsStatistical ManualEpidemiological challengesAddictive disordersConvenience sampleDisordersInadequate assessmentLongitudinal study
2014
Neuroimaging of Eating Disorders, Substance Use Disorders, and Addictions: Overlapping and Unique Systems
Gearhardt A, Boswell R, Potenza M. Neuroimaging of Eating Disorders, Substance Use Disorders, and Addictions: Overlapping and Unique Systems. 2014, 71-89. DOI: 10.1007/978-3-642-45378-6_4.Peer-Reviewed Original ResearchAddictive disordersMemory/learningDomains of impairmentBinge-eating disorderExecutive controlNeural commonalitiesEmotional reactivityInteroceptive awarenessSubstance use disordersEating DisordersBulimia nervosaDimensional approachAnorexia nervosaUse disordersFuture researchDevelopment of treatmentsNervosaDisordersRewardFunctioningMotivationAddictionConceptualizationLearningImpairment
2005
Adolescent Problem Gambling
Grant J, Chambers R, Potenza M. Adolescent Problem Gambling. 2005, 81-98. DOI: 10.1007/0-306-48586-9_5.ChaptersPharmacological treatmentMood stabilizersTreatment strategiesPathological gamblingPromising pharmacological treatmentDefinitive treatment recommendationsHigh prevalence ratesPossible pharmacological interventionsAdolescent pathological gamblingUse of SRIsDrug therapyTreatment recommendationsPharmacological interventionsPrevalence ratesTreatment approachesNeuro-imagingTreatment studiesRisk behaviorsNeurodevelopmental changesAddictive disordersCertain indicationsCertain dosesGood evidenceBehavioral assessmentLongitudinal study