2024
A 10-year perspective on the question of whether surgeries for adolescent idiopathic scoliosis are “one and done”?
Gouzoulis M, Joo P, Jeong S, Jabbouri S, Moran J, Zhu J, Grauer J. A 10-year perspective on the question of whether surgeries for adolescent idiopathic scoliosis are “one and done”? Spine Deformity 2024, 12: 903-908. PMID: 38555557, DOI: 10.1007/s43390-024-00858-3.Peer-Reviewed Original ResearchConceptsAdolescent idiopathic scoliosisIdiopathic scoliosisRisk factorsAssociated with male sexTime of surgeryLong-term outcomesYear follow-upMultivariate regressionMonths to 2Reoperation incidenceReoperation ratePSF patientsExcellent outcomesPediatric surgeonsReoperationMale sexFollow-upStudy cohortPatient characteristicsPatient counselingSurgeryConclusionsThe current studyInterquartile rangeScoliosis fusionResultsIn total
2023
Rheumatoid arthritis patients are at increased risk for adverse events following lumbar discectomy
Ratnasamy P, Rudisill K, Gouzoulis M, Kammien A, Grauer J. Rheumatoid arthritis patients are at increased risk for adverse events following lumbar discectomy. The Spine Journal 2023, 23: 990-996. PMID: 36990283, DOI: 10.1016/j.spinee.2023.03.012.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAntirheumatic AgentsArthritis, RheumatoidDiskectomyHumansReoperationRetrospective StudiesConceptsLumbar discectomy patientsAdverse eventsRheumatoid arthritisLumbar discectomyPatient ageDiscectomy patientsMinor adverse eventsRetrospective cohort studyLumbar spinal surgeryPatient's medication regimenElixhauser Comorbidity IndexExclusion of patientsRA medicationsComorbidity indexCohort studyMedication regimenPrior diagnosisPredictive factorsAdverse outcomesSubgroup analysisSpinal surgeryInfection diagnosisAutoinflammatory diseasesHigher oddsDiscectomy
2022
Incidence, Timing, and Predictors of Hip Dislocation After Primary Total Hip Arthroplasty for Osteoarthritis
Gillinov SM, Joo PY, Zhu JR, Moran J, Rubin LE, Grauer JN. Incidence, Timing, and Predictors of Hip Dislocation After Primary Total Hip Arthroplasty for Osteoarthritis. Journal Of The American Academy Of Orthopaedic Surgeons 2022, 30: 1047-1053. PMID: 35947825, PMCID: PMC9588560, DOI: 10.5435/jaaos-d-22-00150.Peer-Reviewed Original ResearchConceptsPrimary total hip arthroplastyTotal hip arthroplastyElixhauser Comorbidity IndexBody mass indexComorbidity indexMass indexHip dislocationRevision surgeryRisk factorsHip arthroplastyIndex total hip arthroplastyHigher Elixhauser comorbidity indexPrimary THA patientsFirst-time dislocationCumulative incidenceMost patientsPostoperative dataTHA patientsRecurrent episodesControl subjectsFemale sexLarge cohortPatientsMultivariate analysisYounger ageIncidence, Timing, and Risk Factors for 5-Year Revision Surgery After Autologous Chondrocyte Implantation in 533 Patients
Gillinov SM, Fosam A, Burroughs PJ, Schneble CA, McLaughlin WM, Moran J, Jimenez AE, Grauer JN, Medvecky MJ. Incidence, Timing, and Risk Factors for 5-Year Revision Surgery After Autologous Chondrocyte Implantation in 533 Patients. The American Journal Of Sports Medicine 2022, 50: 2893-2899. PMID: 35916771, DOI: 10.1177/03635465221111115.Peer-Reviewed Original ResearchConceptsBony realignment proceduresAutologous chondrocyte implantationBody mass indexPrimary Autologous Chondrocyte ImplantationRevision surgeryRisk factorsRealignment proceduresPostoperative yearKnee arthroplastyFemale sexChondrocyte implantationECI scoresElixhauser comorbidity index scoreChondral defectsComorbidity Index scoreKaplan-Meier analysisLarge national cohortUnicompartmental knee arthroplastyTotal knee arthroplastyOsteochondral allograft transplantationLevel of evidenceOsteochondral autograft transferArticular cartilage proceduresFull-thickness chondral defectsChondral proceduresMarfan syndrome and adolescent idiopathic scoliosis patients have similar 90-day postoperative outcomes and 5-year reoperation rates after spinal deformity surgery
Joo PY, Caruana DL, Gouzoulis MJ, Moore HG, Zhu JR, Ameri B, Grauer JN. Marfan syndrome and adolescent idiopathic scoliosis patients have similar 90-day postoperative outcomes and 5-year reoperation rates after spinal deformity surgery. Spine Deformity 2022, 10: 1169-1174. PMID: 35362940, DOI: 10.1007/s43390-022-00501-z.Peer-Reviewed Original ResearchConceptsAdolescent idiopathic scoliosisMarfan syndromeReoperation rateAIS patientsOdds ratioMFS patientsFive-Year Reoperation RatesNinety-day outcomesMinor adverse eventsMultivariate odds ratiosPosterior spinal fusionSpinal deformity surgeryComorbidity indexAdverse eventsDeformity surgeryAdministrative databasesRelative riskSpinal fusionIdiopathic scoliosisPatientsRepresentative sampleAgeOutcomesSexReadmissionTotal shoulder arthroplasty for osteoarthritis in patients with Parkinson's disease: a matched comparison of 90-day adverse events and 5-year implant survival
Moore HG, Kahan JB, Sherman JJZ, Burroughs PJ, Donohue KW, Grauer JN. Total shoulder arthroplasty for osteoarthritis in patients with Parkinson's disease: a matched comparison of 90-day adverse events and 5-year implant survival. Journal Of Shoulder And Elbow Surgery 2022, 31: 1436-1441. PMID: 35176495, DOI: 10.1016/j.jse.2022.01.113.Peer-Reviewed Original ResearchConceptsTotal shoulder arthroplastyImplant survivalAdverse eventsParkinson's diseaseShoulder arthroplastyDisease cohortDisease populationHigher oddsShort-term adverse eventsNinety-day incidenceChronic kidney diseaseCongestive heart failureCoronary artery diseaseElixhauser Comorbidity IndexLong-term outcomesLog-rank testCase-control studyParkinson's disease cohortParkinson's disease populationShort-term riskPeriprosthetic dislocationComorbidity indexPostoperative periodProsthetic dislocationArtery diseaseGeneral Versus Neuraxial Anesthesia in Revision Surgery for Periprosthetic Joint Infection
Serino J, Galivanche AR, Grauer JN, Haynes M, Karas V, Della Valle CJ. General Versus Neuraxial Anesthesia in Revision Surgery for Periprosthetic Joint Infection. The Journal Of Arthroplasty 2022, 37: s971-s976. PMID: 35017049, DOI: 10.1016/j.arth.2022.01.002.Peer-Reviewed Original ResearchConceptsPeriprosthetic joint infectionNeuraxial anesthesiaAdverse eventsGeneral anesthesiaRevision surgeryJoint infectionLower riskNational Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseQuality Improvement Program databaseMinor adverse eventsSerious adverse eventsThirty-day outcomesImprovement Program databasePropensity-score matchingIntraspinal abscessProgram databaseRevision arthroplastyAmerican CollegeAnesthesiaMultivariate analysisProcedural variablesSurgeryPatientsInfection
2021
Clinical outcomes following one-, two-, three-, and four-level anterior cervical discectomy and fusion: a national database study
Joo PY, Zhu JR, Kammien AJ, Gouzoulis MJ, Arnold PM, Grauer JN. Clinical outcomes following one-, two-, three-, and four-level anterior cervical discectomy and fusion: a national database study. The Spine Journal 2021, 22: 542-548. PMID: 34774751, DOI: 10.1016/j.spinee.2021.11.002.Peer-Reviewed Original ResearchConceptsOne-level casesAnterior cervical discectomyAdverse eventsReoperation rateACDF casesCervical discectomyProlonged lengthFour-level anterior cervical discectomyMultivariate analysisMinor adverse event rateFour-level ACDFNational database studyAdverse event ratesGreater odds ratioCommon surgical procedureLarge national databaseDysphagia ratesElective ACDFLarge comparative studiesComplication ratePatient characteristicsReadmission ratesClinical outcomesPearlDiver databasePosterior proceduresAmbulatory Single-level Posterior Cervical Foraminotomy for Cervical Radiculopathy
Bovonratwet P, Retzky JS, Chen AZ, Ondeck NT, Samuel AM, Qureshi SA, Grauer JN, Albert TJ. Ambulatory Single-level Posterior Cervical Foraminotomy for Cervical Radiculopathy. Clinical Spine Surgery A Spine Publication 2021, 35: e306-e313. PMID: 34654773, DOI: 10.1097/bsd.0000000000001252.Peer-Reviewed Original ResearchConceptsSingle-level posterior cervical foraminotomyPosterior cervical foraminotomyCervical radiculopathyInpatient proceduresCervical foraminotomyPerioperative complicationsAmbulatory proceduresSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databasePropensity scoreRetrospective cohort comparison studyImprovement Program databaseSurgical site infectionCohort comparison studyHospital lengthPain controlPerioperative outcomesPostoperative complicationsThromboembolic eventsWound complicationsNSQIP databasePatient characteristicsSite infectionIndividual complicationsTotal Hip Arthroplasty in Patients With Cerebral Palsy: A Matched Comparison of 90-Day Adverse Events and 5-Year Implant Survival
Moore HG, Gardezi M, Burroughs PJ, Rubin LE, Frumberg DB, Grauer JN. Total Hip Arthroplasty in Patients With Cerebral Palsy: A Matched Comparison of 90-Day Adverse Events and 5-Year Implant Survival. The Journal Of Arthroplasty 2021, 36: 3534-3537. PMID: 34176692, DOI: 10.1016/j.arth.2021.05.039.Peer-Reviewed Original ResearchMeSH KeywordsArthroplasty, Replacement, HipCerebral PalsyHumansReoperationRetrospective StudiesRisk FactorsConceptsTotal hip arthroplastyFive-year implant survivalUrinary tract infectionCerebral palsyImplant survivalAdverse eventsTract infectionsComorbid factorsPeriprosthetic fracturesHigher oddsHip arthroplastyPerioperative urinary tract infectionNinety-day incidencePerioperative adverse eventsLong-term outcomesLog-rank testKaplan-Meier plotsMultivariate logistic regressionPerioperative complicationsPostoperative complicationsCP cohortHospital readmissionMatched ComparisonAdministrative databasesPatientsLong-term Corticosteroid Use Independently Correlates With Complications After Posterior Lumbar Spine Surgery.
Kebaish KJ, Galivanche AR, Varthi AG, Ottesen TD, Rubin LE, Grauer JN. Long-term Corticosteroid Use Independently Correlates With Complications After Posterior Lumbar Spine Surgery. Orthopedics 2021, 44: 172-179. PMID: 34039214, DOI: 10.3928/01477447-20210416-01.Peer-Reviewed Original ResearchConceptsLong-term corticosteroid usePosterior lumbar spine surgeryPosterior lumbar surgeryLumbar spine surgeryPerioperative adverse outcomesCorticosteroid useAdverse eventsLumbar surgerySpine surgeryPropensity matchingAdverse outcomesNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseMinor adverse eventsEffect of immunosuppressionImprovement Program databaseLong-term corticosteroidsSerious adverse eventsBody mass indexMultiple surgical specialtiesAnesthesiologists classComparable patientsPerioperative outcomesSurgical factorsMore patients
2020
Pediatric Supracondylar Humerus Fracture Outcomes by Pediatric and Nonpediatric Orthopedists.
Mets EJ, Grauer JN, McLynn RP, Frumberg DB. Pediatric Supracondylar Humerus Fracture Outcomes by Pediatric and Nonpediatric Orthopedists. Orthopedics 2020, 44: e203-e210. PMID: 33316820, DOI: 10.3928/01477447-20201210-03.Peer-Reviewed Original ResearchConceptsPediatric supracondylar humerus fracturesSupracondylar humerus fracturesHumerus fracturesMultivariate analysisRetrospective comparative cohort analysisLarge national databaseComparative cohort analysisComorbidity burdenHospital lengthPerioperative outcomesAdverse eventsPatient characteristicsPatient factorsFracture outcomesOperative timePatient 1Surgical interventionAdverse outcomesPediatric orthopedistsStudy groupCohort analysisOrthopaedic surgeonsOrthopedistsNational databaseSubspecialty trainingThirty-Day Readmissions After Aseptic Revision Total Hip Arthroplasty: Rates, Predictors, and Reasons Vary by Surgical Indication
Pathak N, Kahlenberg CA, Moore HG, Sculco PK, Grauer JN. Thirty-Day Readmissions After Aseptic Revision Total Hip Arthroplasty: Rates, Predictors, and Reasons Vary by Surgical Indication. The Journal Of Arthroplasty 2020, 35: 3673-3678. PMID: 32684401, DOI: 10.1016/j.arth.2020.06.069.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement ProgramThirty-day readmissionTotal hip arthroplastyRecurrent dislocationSurgical indicationsAseptic looseningPeriprosthetic fracturesPostoperative dislocationHip arthroplastyAseptic revision total hip arthroplastyMultivariate analysisPatients meeting inclusion criteriaSurgical Quality Improvement ProgramRevision total hip arthroplastyDifferent surgical indicationsPostoperative care pathwaysMeeting inclusion criteriaQuality Improvement ProgramFurther multivariate analysisAseptic indicationsFracture cohortPostoperative predictorsReadmission ratesReadmission riskCare pathway
2019
Admission NarxCare Narcotics Scores are not Associated With Adverse Surgical Outcomes or Self-reported Patient Satisfaction Following Elective Spine Surgery.
Galivanche AR, Mercier MR, Adrados M, Pathak N, McLynn RP, Anandasivam NS, Varthi AG, Rubin LE, Grauer JN. Admission NarxCare Narcotics Scores are not Associated With Adverse Surgical Outcomes or Self-reported Patient Satisfaction Following Elective Spine Surgery. Spine 2019, 44: 1515-1522. PMID: 31356498, DOI: 10.1097/brs.0000000000003120.Peer-Reviewed Original ResearchConceptsMultivariate logistic regressionPatient satisfactionAdverse eventsNarcotic scoreSurvey response rateSpine surgeryResponse rateLogistic regressionSelf-reported patient satisfactionElective spine surgeryPreoperative opioid usePostoperative patient satisfactionTime of admissionAdverse surgical outcomesSpine surgery casesHospital Consumer AssessmentHCAHPS survey resultsDifferent narcoticsNarcotic usagePerioperative outcomesNarcotic utilizationOpioid usePatient characteristicsPostoperative outcomesNarcotic groupIncidence, Risk Factors, and Clinical Implications of Postoperative Hematoma Requiring Reoperation Following Anterior Cervical Discectomy and Fusion
Bovonratwet P, Fu MC, Tyagi V, Bohl DD, Ondeck NT, Albert TJ, Grauer JN. Incidence, Risk Factors, and Clinical Implications of Postoperative Hematoma Requiring Reoperation Following Anterior Cervical Discectomy and Fusion. Spine 2019, Publish Ahead of Print: &na;. PMID: 30247374, DOI: 10.1097/brs.0000000000002885.Peer-Reviewed Original ResearchConceptsAnterior cervical discectomyRisk factorsPostoperative hematomaCervical discectomyNational Surgical Quality Improvement Program databaseClinical implicationsPreoperative international normalized ratioQuality Improvement Program databaseDeep wound infectionHigh-risk patientsImprovement Program databaseDevelopment of hematomaInternational normalized ratioLarge cohort studyOccurrence of hematomaACDF patientsPreoperative anemiaVentilator requirementAnesthesiologists classificationPostoperative lengthCohort studyPerioperative periodCatastrophic complicationPrimary outcomeSubsequent complications
2018
Dialysis is an independent risk factor for perioperative adverse events, readmission, reoperation, and mortality for patients undergoing elective spine surgery
Ottesen TD, McLynn RP, Zogg CK, Shultz BN, Ondeck NT, Bovonratwet P, Bellamkonda KS, Rubin LE, Grauer JN. Dialysis is an independent risk factor for perioperative adverse events, readmission, reoperation, and mortality for patients undergoing elective spine surgery. The Spine Journal 2018, 18: 2033-2042. PMID: 30077772, DOI: 10.1016/j.spinee.2018.04.007.Peer-Reviewed Original ResearchConceptsElective spine surgeryNon-dialysis patientsDialysis-dependent patientsPerioperative adverse eventsAdverse eventsDialysis patientsSpine surgeryUnplanned readmissionCohort studyPatient demographicsRisk factorsNational Surgical Quality Improvement Program databaseRisk-adjusted multivariate regressionsQuality Improvement Program databaseOperating roomDialysis-independent patientsInstitutional cohort studyMinor adverse eventsRetrospective cohort studyElective spinal surgeryImprovement Program databaseIndependent risk factorMajor adverse eventsPercentage of complicationsAdministrative database studyDialysis Patients Undergoing Total Knee Arthroplasty Have Significantly Increased Odds of Perioperative Adverse Events Independent of Demographic and Comorbidity Factors
Ottesen TD, Zogg CK, Haynes MS, Malpani R, Bellamkonda KS, Grauer JN. Dialysis Patients Undergoing Total Knee Arthroplasty Have Significantly Increased Odds of Perioperative Adverse Events Independent of Demographic and Comorbidity Factors. The Journal Of Arthroplasty 2018, 33: 2827-2834. PMID: 29754981, DOI: 10.1016/j.arth.2018.04.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overArthroplasty, Replacement, KneeComorbidityElective Surgical ProceduresFemaleHumansInpatientsLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient DischargePatient ReadmissionPostoperative ComplicationsQuality ImprovementRegression AnalysisRenal DialysisReoperationRetrospective StudiesRisk AssessmentConceptsTotal knee arthroplastyDialysis-dependent patientsAdverse eventsPatient demographicsDialysis patientsAdverse outcomesKnee arthroplastyNational Surgical Quality Improvement Program databaseOverall healthRisk-adjusted logistic regressionElective total knee arthroplastyQuality Improvement Program databaseImprovement Program databaseMinor adverse eventsNational inpatient databaseSevere adverse eventsBone health statusNondialysis cohortNondialysis patientsPerioperative periodTKA patientsAdult patientsPreoperative riskComorbidity factorsInstitutional cohortAseptic revision total hip arthroplasty in the elderly : quantifying the risks for patients over 80 years old.
Bovonratwet P, Malpani R, Ottesen TD, Tyagi V, Ondeck NT, Rubin LE, Grauer JN. Aseptic revision total hip arthroplasty in the elderly : quantifying the risks for patients over 80 years old. The Bone & Joint Journal 2018, 100-B: 143-151. PMID: 29437055, DOI: 10.1302/0301-620x.100b2.bjj-2017-0895.r1.Peer-Reviewed Original ResearchConceptsAseptic revision total hip arthroplastyRevision total hip arthroplastyTotal hip arthroplastySerious adverse eventsAdverse eventsRisk factorsProcedural characteristicsHip arthroplastyNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseImprovement Program databaseIndependent risk factorUrinary tract infectionMultivariate regression analysisAnesthesiologists (ASA) scoreMedical optimizationPerioperative complicationsPerioperative mortalityPostoperative complicationsTract infectionsYounger patientsBlood transfusionGeneral anesthesiaVulnerable patientsBone Joint
2017
Similar 30-Day Complications for Septic Knee Arthritis Treated With Arthrotomy or Arthroscopy: An American College of Surgeons National Surgical Quality Improvement Program Analysis
Bovonratwet P, Nelson SJ, Bellamkonda K, Ondeck NT, Shultz BN, Medvecky MJ, Grauer JN. Similar 30-Day Complications for Septic Knee Arthritis Treated With Arthrotomy or Arthroscopy: An American College of Surgeons National Surgical Quality Improvement Program Analysis. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2017, 34: 213-219. PMID: 28866341, DOI: 10.1016/j.arthro.2017.06.046.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement ProgramSurgery treatment groupPerioperative complicationsSeptic kneeAdverse eventsTreatment groupsTreatment modalitiesOpen arthrotomyAmerican CollegeSurgeons National Surgical Quality Improvement Program analysisNational Surgical Quality Improvement Program analysisSurgeons National Surgical Quality Improvement ProgramMultivariate analysisSurgical Quality Improvement ProgramOperating roomSeptic knee arthritisSimilar perioperative complicationsMinor adverse eventsRate of readmissionSerious adverse eventsRetrospective comparative studyNSQIP data setsSignificant differencesQuality Improvement ProgramPatient demographicsPredicting Postoperative Morbidity and Readmission for Revision Posterior Lumbar Fusion
Basques BA, Ibe I, Samuel AM, Lukasiewicz AM, Webb ML, Bohl DD, Grauer JN. Predicting Postoperative Morbidity and Readmission for Revision Posterior Lumbar Fusion. Clinical Spine Surgery A Spine Publication 2017, 30: e770-e775. PMID: 27280782, DOI: 10.1097/bsd.0000000000000391.Peer-Reviewed Original ResearchConceptsMinor adverse eventsSevere adverse eventsInsulin-dependent diabetesAdverse eventsPosterior lumbar fusionLumbar fusionRisk factorsASA classificationOperative timeSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseMultivariate analysisBody mass index 25Quality Improvement Program databaseImprovement Program databaseRetrospective cohort studySpecific risk factorsAnesthesiologists classificationBMI 30Postoperative complicationsPostoperative morbidityCohort studyPatient characteristicsSicker patientsAdverse outcomes