2024
Utilization and timing of surgical intervention for central cord syndrome in the United States
Dhodapkar M, Halperin S, Seddio A, Dahodwala T, Rubio D, Grauer J. Utilization and timing of surgical intervention for central cord syndrome in the United States. European Spine Journal 2024, 33: 3645-3651. PMID: 39103615, DOI: 10.1007/s00586-024-08431-2.Peer-Reviewed Original ResearchCentral cord syndromeSurgical interventionAbsence of bony injuryOperative interventionCord syndromeBony injuriesPredictors of operative managementAbsence of vertebral fracturesTiming of surgical interventionTiming of operative interventionCohort of patientsProportion of patientsDays of diagnosisHigher comorbidity burdenVertebral fracturesSpinal cord injuryMethodsAdult patientsNon-operativelyNonsurgical interventionsMultivariate analysisStudy assessed utilizationComorbidity burdenIncomplete spinal cord injuryPatientsInclusion criteria
2023
Low Back Pain: Utilization of Urgent Cares Relative to Emergency Departments
Dhodapkar M, Modrak M, Halperin S, Gouzoulis M, Rubio D, Grauer J. Low Back Pain: Utilization of Urgent Cares Relative to Emergency Departments. Spine 2023, 49: 513-517. PMID: 37982595, DOI: 10.1097/brs.0000000000004880.Peer-Reviewed Original ResearchLow back painElixhauser Comorbidity IndexUrgent care centersEmergency departmentUrgent careBack painED visitsED utilizationCare centerAdvanced imagingUrgent care useUrgent care visitsDays of diagnosisSetting of traumaSpinal cord injuryYears of ageComorbidity indexInfectious diagnosisCare visitsLBP patientsMost patientsRecent surgeryAdult patientsPatient ageED patients
2021
Spinal fractures and/or spinal cord injuries are associated with orthopedic and internal organ injuries in proximity to the spinal injury
Anandasivam NS, Ondeck NT, Bagi PS, Galivanche AR, Samuel AM, Bohl DD, Grauer JN. Spinal fractures and/or spinal cord injuries are associated with orthopedic and internal organ injuries in proximity to the spinal injury. North American Spine Society Journal (NASSJ) 2021, 6: 100057. PMID: 35141623, PMCID: PMC8820026, DOI: 10.1016/j.xnsj.2021.100057.Peer-Reviewed Original ResearchSpine injury patientsNational Trauma Data BankThoracic spine injuriesMechanism of injuryInternal organ injuriesSpinal cord injurySpine injuriesMotor vehicle accidentsLung injuryIntracranial injuryInjury patientsSpinal fracturesCord injurySpinal injuryRib injuriesComorbidity burdenOrgan injuryInjury severityCervical spine injury patientsAcute spinal injuryLumbar spinal fracturesPredominance of injuriesNumber of comorbiditiesCervical spine injuryTrauma Data Bank
2018
Thromboembolic Events After Traumatic Vertebral Fractures
Samuel AM, Diaz-Collado PJ, Gala RJ, Webb ML, Lukasiewicz AM, Basques BA, Bohl DD, Kim HJ, Grauer JN. Thromboembolic Events After Traumatic Vertebral Fractures. Spine 2018, 43: 1289-1295. PMID: 29538240, DOI: 10.1097/brs.0000000000002634.Peer-Reviewed Original ResearchConceptsVenous thromboembolism eventsTraumatic vertebral fracturesVertebral fracturesSpinal cord injuryOdds ratioCord injuryRisk factorsNational Trauma Data Bank Research Data SetLonger inpatient lengthPulmonary embolism eventsDeep vein thrombosisHigh-energy injuriesVertebral fracture patientsLength of stayAdditional risk factorsMultivariate logistic regressionSuch adverse outcomesOverall rateThromboembolism eventsHospital courseThromboembolic eventsFracture patientsVein thrombosisLonger LOSTrauma patientsFrequency and Acceptability of Adverse Events After Anterior Cervical Discectomy and Fusion
Wilson JR, Radcliff K, Schroeder G, Booth M, Lucasti C, Fehlings M, Ahmad N, Vaccaro A, Arnold P, Sciubba D, Ching A, Smith J, Shaffrey C, Singh K, Darden B, Daffner S, Cheng I, Ghogawala Z, Ludwig S, Buchowski J, Brodke D, Wang J, Lehman RA, Hilibrand A, Yoon T, Grauer J, Dailey A, Steinmetz M, Harrop JS. Frequency and Acceptability of Adverse Events After Anterior Cervical Discectomy and Fusion. Clinical Spine Surgery A Spine Publication 2018, 31: e270-e277. PMID: 29708891, DOI: 10.1097/bsd.0000000000000645.Peer-Reviewed Original ResearchConceptsAnterior cervical discectomyAdverse eventsCervical discectomyPrimary specialtyPractice locationAdjacent segment diseaseSpinal cord injuryUS surgeonsWrong-level surgeryFuture quality improvementComplication eventsAcceptable complicationsUncommon complicationEsophageal injuryLevel surgeryCord injurySegment diseaseSpine surgerySurgeon experienceOrthopaedic surgeonsSurgeons' opinionsComplicationsDiscectomyMajority of respondentsSurgeons
2016
Spinal Fracture in Patients With Ankylosing Spondylitis
Lukasiewicz AM, Bohl DD, Varthi AG, Basques BA, Webb ML, Samuel AM, Grauer JN. Spinal Fracture in Patients With Ankylosing Spondylitis. Spine 2016, 41: 191-196. PMID: 26579959, DOI: 10.1097/brs.0000000000001190.Peer-Reviewed Original ResearchConceptsNational Inpatient SampleSpinal fracturesAdverse eventsCervical fracturesSpinal columnHospital adverse eventsMortality of fracturesSmall case seriesSpinal cord injuryAnkylosed spinePatient demographicsRetrospective cohortThoracic fracturesCase seriesHigh morbidityInjury characteristicsInpatient stayMinor traumaCord injuryPatient populationCase reportInpatient SampleBACKGROUND DATAHigh riskPatients
2015
Analysis of Delays to Surgery for Cervical Spinal Cord Injuries
Samuel AM, Bohl DD, Basques BA, Diaz-Collado PJ, Lukasiewicz AM, Webb ML, Grauer JN. Analysis of Delays to Surgery for Cervical Spinal Cord Injuries. Spine 2015, 40: 992-1000. PMID: 25785963, DOI: 10.1097/brs.0000000000000883.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCervical VertebraeChi-Square DistributionComorbidityDatabases, FactualDecompression, SurgicalFemaleHumansKaplan-Meier EstimateLinear ModelsMaleMiddle AgedMultivariate AnalysisPatient AdmissionRetrospective StudiesRisk AssessmentRisk FactorsSpinal Cord InjuriesTime FactorsTime-to-TreatmentTreatment OutcomeYoung AdultConceptsCervical spinal cord injuryIncomplete spinal cord injurySpinal cord injuryNational Trauma Data Bank Research Data SetCentral spinal cord injuryComplete spinal cord injuryLate surgeryCord injuryUpper cervical spinal cord injuryGreater Charlson Comorbidity IndexSuperior neurological outcomeCharlson Comorbidity IndexMajority of patientsComorbidity indexNeurological outcomeUnderwent surgerySurgical timingInjury characteristicsRetrospective studyEmergency departmentInpatient admissionsPatient populationSurgery occurBACKGROUND DATAPatientsDelayed Surgery After Acute Traumatic Central Cord Syndrome Is Associated With Reduced Mortality
Samuel AM, Grant RA, Bohl DD, Basques BA, Webb ML, Lukasiewicz AM, Diaz-Collado PJ, Grauer JN. Delayed Surgery After Acute Traumatic Central Cord Syndrome Is Associated With Reduced Mortality. Spine 2015, 40: 349-356. PMID: 25757037, DOI: 10.1097/brs.0000000000000756.Peer-Reviewed Original ResearchConceptsAcute traumatic central cord syndromeTraumatic central cord syndromeCentral cord syndromeMinor adverse eventsSerious adverse eventsAdverse eventsAssociation of timeCord syndromeNational Trauma Data Bank Research Data SetNational Trauma Data Bank Research DataInjury severityPre-existing comorbidityCharlson Comorbidity IndexPre-existing comorbiditiesInjury Severity ScoreOdds of mortalityMultivariate logistic regressionSpinal cord injurySpinal cord recoveryPotential neurological effectsComorbidity indexEarly surgeryMedical optimizationInpatient mortalitySurgical timing
2009
Differences between neurosurgeons and orthopedic surgeons in classifying cervical dislocation injuries and making assessment and treatment decisions: a multicenter reliability study.
Arnold PM, Brodke DS, Rampersaud YR, Harrop JS, Dailey AT, Shaffrey CI, Grauer JN, Dvorak MF, Bono CM, Wilsey JT, Lee JY, Nassr A, Vaccaro AR. Differences between neurosurgeons and orthopedic surgeons in classifying cervical dislocation injuries and making assessment and treatment decisions: a multicenter reliability study. The American Journal Of Orthopedics 2009, 38: e156-61. PMID: 20011745.Peer-Reviewed Original ResearchConceptsSpinal cord injuryMagnetic resonance imagingPretreatment magnetic resonance imagingCervical dislocation injuriesDislocation injuriesSpine surgeonsIncomplete spinal cord injuryComplete spinal cord injuryCervical spinal injuryBilateral facet dislocationImmediate closed reductionMulticenter reliability studyIntact patientsCervical injuryClosed reductionFacet dislocationCord injurySpinal injuryTreatment decisionsCervical dislocationTherapeutic implicationsClinical scenariosOrthopaedic surgeonsInjuryResonance imagingThe Timing and Influence of MRI on the Management of Patients With Cervical Facet Dislocations Remains Highly Variable
Grauer JN, Vaccaro AR, Lee JY, Nassr A, Dvorak MF, Harrop JS, Dailey AT, Shaffrey CI, Arnold PM, Brodke DS, Rampersaud R. The Timing and Influence of MRI on the Management of Patients With Cervical Facet Dislocations Remains Highly Variable. Clinical Spine Surgery A Spine Publication 2009, 22: 96-99. PMID: 19342930, DOI: 10.1097/bsd.0b013e31816a9ebd.Peer-Reviewed Original ResearchMeSH KeywordsCervical VertebraeClinical ProtocolsData CollectionDecision Support TechniquesJoint DislocationsJointsMagnetic Resonance ImagingNeurosurgeryObserver VariationOrthopedicsPractice Patterns, Physicians'Professional PracticeSpinal FracturesSpinal FusionSpinal InjuriesSurveys and QuestionnairesTime FactorsTomography, X-Ray ComputedTractionConceptsTraumatic cervical facet dislocationCervical facet dislocationMagnetic resonance imagingComplete spinal cord injuryInfluence of MRIManagement of patientsFacet dislocationSpinal cord injuryOpen reductionCord injuryOrthopaedic surgeonsUtilization of MRIEvidence-based algorithmDifferent clinical scenariosDevastating injuriesNeurologic examinationDisc herniationLigamentous disruptionPlain radiographsClosed treatmentTomography scanPatient managementTreatment decisionsOpen treatmentSpine surgeonsUtility of Helical Computed Tomography in Differentiating Unilateral and Bilateral Facet Dislocations
Dailey AT, Shaffrey CI, Rampersaud R, Lee J, Brodke DS, Arnold P, Nassr A, Harrop JS, Grauer J, Bono CM, Dvorak M, Vaccaro A. Utility of Helical Computed Tomography in Differentiating Unilateral and Bilateral Facet Dislocations. Journal Of Spinal Cord Medicine 2009, 32: 43-48. PMID: 19264048, PMCID: PMC2647499, DOI: 10.1080/10790268.2009.11760751.Peer-Reviewed Original ResearchConceptsCervical facet dislocationBilateral facet dislocationHelical computed tomographyFacet dislocationComputed tomographyRadiographic studiesUnilateral cervical facet dislocationUnilateral facet dislocationSpinal cord injuryVertebral body translationDifferent clinical scenariosTranslational injuriesNeurologic injuryNeurologic statusPlain radiographsCord injuryUnilateral dislocationClinical historySurgeon's interpretationUnilateral fracturesIntraoperative observationsIntraoperative diagnosisAxial CT slicesSagittal reconstructionsSpine surgeons
2008
Variations in Surgical Treatment of Cervical Facet Dislocations
Nassr A, Lee JY, Dvorak MF, Harrop JS, Dailey AT, Shaffrey CI, Arnold PM, Brodke DS, Rampersaud R, Grauer JN, Winegar C, Vaccaro AR. Variations in Surgical Treatment of Cervical Facet Dislocations. Spine 2008, 33: e188-e193. PMID: 18379387, DOI: 10.1097/brs.0b013e3181696118.Peer-Reviewed Original ResearchConceptsCervical facet dislocationSurgical approachDisc herniationFacet dislocationNeurologic statusAnterior approachBilateral injuryCervical dislocationTraumatic cervical facet dislocationComplete spinal cord injurySpine Trauma Study GroupOnly slight agreementBilateral facet dislocationSpinal cord injuryRetrospective survey analysisSurgical treatmentCord injuryPosterior approachSurgeon preferenceInter-rater reliabilitySurgeon's interpretationTreatment decisionsBACKGROUND DATAStudy groupHerniation
2007
A Quantitative and Reproducible Method to Assess Cord Compression and Canal Stenosis After Cervical Spine Trauma
Furlan JC, Fehlings MG, Massicotte EM, Aarabi B, Vaccaro AR, Bono CM, Madrazo I, Villanueva C, Grauer JN, Mikulis D. A Quantitative and Reproducible Method to Assess Cord Compression and Canal Stenosis After Cervical Spine Trauma. Spine 2007, 32: 2083-2091. PMID: 17762809, DOI: 10.1097/brs.0b013e318145a91c.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedCervical VertebraeFemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedNorth AmericaObserver VariationPrognosisReproducibility of ResultsSeverity of Illness IndexSignal Processing, Computer-AssistedSpinal Cord CompressionSpinal Cord InjuriesSpinal StenosisTomography, X-Ray ComputedConceptsMaximum spinal cord compressionTraumatic cervical spinal cord injuryCervical spinal cord injuryMaximum canal compromiseSpinal cord injuryInterclass correlation coefficientCord compressionIntrarater reliabilityAcute traumatic cervical spinal cord injuryTraumatic spinal cord injuryCervical spine traumaSpinal cord compressionT1-weighted MRIT2-weighted MR imagesCanal stenosisCanal compromiseSpine traumaPrognostic valueCord injuryRadiologic parametersCervical spineBACKGROUND DATACT scanMidsagittal MRIInterrater ICC
2006
Subaxial cervical spine trauma.
Kwon BK, Vaccaro AR, Grauer JN, Fisher CG, Dvorak MF. Subaxial cervical spine trauma. Journal Of The American Academy Of Orthopaedic Surgeons 2006, 14: 78-89. PMID: 16467183, DOI: 10.5435/00124635-200602000-00003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSubaxial cervical spine injuriesCervical spine injurySpinal cord injurySpine injuriesCord injuryAcute spinal cord injurySevere spinal cord injuryCertain injury patternsAdministration of methylprednisoloneSpinous process fractureSubaxial cervical injuriesAccurate clinical historyCareful physical examinationNeurologic statusDefinitive managementNonsurgical managementPatient factorsCervical injuryClosed reductionNeurologic impairmentProcess fracturesEmergent managementInjury patternsPhysical examinationRadiographic evaluation
2004
Pathophysiology and pharmacologic treatment of acute spinal cord injury
Kwon BK, Tetzlaff W, Grauer JN, Beiner J, Vaccaro AR. Pathophysiology and pharmacologic treatment of acute spinal cord injury. The Spine Journal 2004, 4: 451-464. PMID: 15246307, DOI: 10.1016/j.spinee.2003.07.007.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryCord injuryPathophysiologic processesPharmacologic treatmentNeuroprotective agentsSecondary damageImportant pathophysiologic processSecondary injury cascadePharmacologic therapyAcute treatmentInjury cascadeNeurologic functionNeuroprotective strategiesDevastating injuriesPathophysiologic mechanismsSpecific therapyPathophysiologic eventsSpinal cordHuman trialsPotential therapyInjuryAnimal dataLiterature reviewTherapy