2024
P31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy
Seddio A, Gouzoulis M, Smith-Voudouris J, Rubio D, Day W, Grauer J. P31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy. The Spine Journal 2024, 24: s78. DOI: 10.1016/j.spinee.2024.06.052.Peer-Reviewed Original ResearchTestosterone replacement therapyAcute kidney injuryLumbar discectomyAdverse eventsMale patientsOdds ratioCurrent Procedural TerminologyReoperation ratePostoperative outcomesElixhauser Comorbidity IndexPostoperative recoveryMultivariate analysisSingle-level lumbar discectomyTestosterone replacement therapy patientsMyocardial infarctionOrthopedic surgeryKaplan-Meier survival analysisEmergency departmentLumbar spinal proceduresLog-rank testMonths of surgeryRetrospective cohort studyPostoperative adverse eventsEnhanced postoperative recoveryMinor adverse events100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Zhu J, Rubio D, Grauer J. 100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024, 24: s52-s53. DOI: 10.1016/j.spinee.2024.06.543.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsImpact of semaglutideHospital readmissionPostoperative outcomesElixhauser Comorbidity IndexED visitsT2DM patientsCurrent Procedural TerminologyEmergency departmentLumbar fusionAdverse eventsOdds of hospital readmissionOutcome measures IncidenceRisk of type I errorInferior postoperative outcomesDiagnosis of T2DMMonths of surgeryYear of surgeryRetrospective cohort studyMinor adverse eventsType II diabetes mellitusMatched 1:4Management of diabetes
2023
Ninety day adverse events following single level posterior lumbar interbody fusion in patients with sickle cell disease
Dhodapkar M, Halperin S, Saifi C, Whang P, Grauer J, Varthi A. Ninety day adverse events following single level posterior lumbar interbody fusion in patients with sickle cell disease. The Spine Journal 2023, 24: 807-811. PMID: 38081460, DOI: 10.1016/j.spinee.2023.11.025.Peer-Reviewed Original ResearchPosterior lumbar interbody fusionSingle-level posterior lumbar interbody fusionSickle cell diseaseElixhauser Comorbidity IndexAdverse eventsPostoperative outcomesInterbody fusionOdds ratioCell diseaseDays adverse eventsMinor adverse eventsPostoperative adverse eventsPerioperative adverse eventsSevere adverse eventsCohort of patientsED visit ratesEmergency department visitsMultivariable logistic regressionNational administrative databaseRetrospective database studyLumbar interbody fusionSingle level posteriorComorbidity indexPLIF patientsAdult patients
2022
Admission NarxCare Narcotic Scores Are Associated With Increased Odds of Readmission and Prolonged Length of Hospital Stay After Primary Elective Total Knee Arthroplasty
Galivanche A, Zhu J, Mercier M, McLean R, Wilhelm C, Varthi A, Grauer J, Rubin L. Admission NarxCare Narcotic Scores Are Associated With Increased Odds of Readmission and Prolonged Length of Hospital Stay After Primary Elective Total Knee Arthroplasty. JAAOS Global Research And Reviews 2022, 6: e22.00040. PMID: 36732305, PMCID: PMC9726283, DOI: 10.5435/jaaosglobal-d-22-00040.Peer-Reviewed Original ResearchConceptsPrimary elective total knee arthroplastyElective total knee arthroplastyTotal knee arthroplastyNarcotic scoreOverall opioid usageAdverse eventsTKA patientsHospital stayKnee arthroplastyRisk of AEsOdds of readmissionPrimary TKA patientsPreoperative narcotic useTime of admissionDose-dependent increaseOpioid usagePostoperative outcomesPatient characteristicsProlonged lengthNarcotic useAdverse outcomesSingle institutionRevision surgeryReadmissionPatientsComparison of postoperative outcomes in patients with and without osteoporosis undergoing single-level anterior cervical discectomy and fusion
Kammien AJ, Galivanche AR, Joo PY, Elaydi A, Whang P, Saifi C, Grauer JN, Varthi A. Comparison of postoperative outcomes in patients with and without osteoporosis undergoing single-level anterior cervical discectomy and fusion. North American Spine Society Journal (NASSJ) 2022, 12: 100174. PMID: 36299450, PMCID: PMC9589019, DOI: 10.1016/j.xnsj.2022.100174.Peer-Reviewed Original ResearchSingle-level anterior cervical discectomyAnterior cervical discectomyAdverse eventsCervical discectomySingle-level ACDF proceduresSurgical planningComorbidity-matched patientsPerioperative adverse eventsSingle-level ACDFLog-rank analysisLong-term outcomesNational administrative databaseSetting of osteoporosisACDF proceduresConcomitant proceduresPatient characteristicsPostoperative outcomesGraft subsidenceOsteoporosis groupBony unionPatient counselingPatient counsellingAdministrative databasesReoperationExclusion criteria
2021
Hospital Consumer Assessment of Healthcare Providers and Systems survey response rates are significantly affected by patient characteristics and postoperative outcomes for patients undergoing primary total knee arthroplasty
Mercier MR, Galivanche AR, David WB, Malpani R, Pathak N, Hilibrand AS, Rubin LE, Grauer JN. Hospital Consumer Assessment of Healthcare Providers and Systems survey response rates are significantly affected by patient characteristics and postoperative outcomes for patients undergoing primary total knee arthroplasty. PLOS ONE 2021, 16: e0257555. PMID: 34582475, PMCID: PMC8478166, DOI: 10.1371/journal.pone.0257555.Peer-Reviewed Original ResearchConceptsTotal knee arthroplastyPrimary total knee arthroplastyHospital Consumer AssessmentPostoperative outcomesPatient characteristicsHCAHPS survey resultsHCAHPS surveySurvey response rateKnee arthroplastyResponse rateHealthcare providersConsumer AssessmentHigher American SocietyMultivariate regression analysisAnesthesia scorePostoperative variablesTKA patientsAdult patientsPrimary outcomePatient factorsSurgical variablesPatient populationPatient satisfactionSingle institutionHospital experiencePredictors and Sequelae of Postoperative Delirium in a Geriatric Patient Population With Hip Fracture
Haynes MS, Alder KD, Toombs C, Amakiri IC, Rubin LE, Grauer JN. Predictors and Sequelae of Postoperative Delirium in a Geriatric Patient Population With Hip Fracture. JAAOS Global Research And Reviews 2021, 5: e20.00221. PMID: 33989253, PMCID: PMC8133215, DOI: 10.5435/jaaosglobal-d-20-00221.Peer-Reviewed Original ResearchConceptsHip fracture populationPostoperative deliriumPreoperative dementiaHip fractureGeriatric hip fracture populationDependent functional statusFracture populationAdverse postoperative outcomesHigher American SocietyIndependent risk factorPostoperative adverse outcomesGeriatric patient populationNongeneral anesthesiaPreoperative diabetesPostoperative outcomesIndependent predictorsMale sexAdverse outcomesPatient populationFunctional statusRevision surgeryRisk factorsDeliriumHigher oddsRisk subpopulationsSpine Surgery HCAHPS Patient Satisfaction Survey Results Inversely Correlate with Survey Response Time
Kebaish KJ, Mercier MR, Duy PQ, Malpani R, Galivanche AR, Grauer JN. Spine Surgery HCAHPS Patient Satisfaction Survey Results Inversely Correlate with Survey Response Time. Spine 2021, 46: 1264-1270. PMID: 34435990, DOI: 10.1097/brs.0000000000003974.Peer-Reviewed Original ResearchConceptsHCAHPS surveySurgery patientsSpinal surgery patientsSpine surgery patientsPatient satisfaction surveyHospital Consumer AssessmentPatient satisfaction metricsAcademic medical centerMultivariate regression analysisLower scoresSurvey response timeAnesthesiologists classPatient demographicsPostoperative outcomesRetrospective reviewFunctional statusSpine surgeryBACKGROUND DATAMedical CenterPatient experienceDay 22Day 43Healthcare providersDay 0Reported satisfaction
2020
Safety and Effectiveness of Antifibrinolytics in Posterior Scoliosis Surgery for Adolescent Idiopathic Scoliosis
Bovonratwet P, Sheha ED, Ondeck NT, Malpani R, Smith BG, Grauer JN. Safety and Effectiveness of Antifibrinolytics in Posterior Scoliosis Surgery for Adolescent Idiopathic Scoliosis. Clinical Spine Surgery A Spine Publication 2020, 33: e26-e32. PMID: 31162181, DOI: 10.1097/bsd.0000000000000836.Peer-Reviewed Original ResearchConceptsAdolescent idiopathic scoliosisPosterior spinal fusionMultilevel posterior spinal fusionIntensive care unitAntifibrinolytic useHospital lengthCare unitTreatment groupsIdiopathic scoliosisOperating roomEffectiveness of antifibrinolyticsNSQIP-Pediatric databasePediatric deformity surgeryPerioperative transfusion ratesVolume of transfusionLonger operative timePosterior scoliosis surgeryLarge national databaseTransfusion reductionPerioperative complicationsPostoperative complicationsTransfusion ratePostoperative outcomesPediatric patientsOperative time
2019
Admission NarxCare Narcotics Scores are not Associated With Adverse Surgical Outcomes or Self-reported Patient Satisfaction Following Elective Spine Surgery.
Galivanche AR, Mercier MR, Adrados M, Pathak N, McLynn RP, Anandasivam NS, Varthi AG, Rubin LE, Grauer JN. Admission NarxCare Narcotics Scores are not Associated With Adverse Surgical Outcomes or Self-reported Patient Satisfaction Following Elective Spine Surgery. Spine 2019, 44: 1515-1522. PMID: 31356498, DOI: 10.1097/brs.0000000000003120.Peer-Reviewed Original ResearchConceptsMultivariate logistic regressionPatient satisfactionAdverse eventsNarcotic scoreSurvey response rateSpine surgeryResponse rateLogistic regressionSelf-reported patient satisfactionElective spine surgeryPreoperative opioid usePostoperative patient satisfactionTime of admissionAdverse surgical outcomesSpine surgery casesHospital Consumer AssessmentHCAHPS survey resultsDifferent narcoticsNarcotic usagePerioperative outcomesNarcotic utilizationOpioid usePatient characteristicsPostoperative outcomesNarcotic group
2018
Systematic Changes in the National Surgical Quality Improvement Program Database Over the Years Can Affect Comorbidity Indices Such as the Modified Frailty Index and Modified Charlson Comorbidity Index for Lumbar Fusion Studies
Shultz BN, Ottesen TD, Ondeck NT, Bovonratwet P, McLynn RP, Cui JJ, Grauer JN. Systematic Changes in the National Surgical Quality Improvement Program Database Over the Years Can Affect Comorbidity Indices Such as the Modified Frailty Index and Modified Charlson Comorbidity Index for Lumbar Fusion Studies. Spine 2018, 43: 798-804. PMID: 28922281, DOI: 10.1097/brs.0000000000002418.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseCharlson Comorbidity IndexImprovement Program databaseComorbidity indexFrailty indexNSQIP databaseProgram databaseSurgeons National Surgical Quality Improvement Program databaseElective posterior lumbar fusionModified Charlson Comorbidity IndexModified Frailty IndexAdverse postoperative outcomesRetrospective cohort studyMean American SocietyMean ASA scorePosterior lumbar fusionAnesthesiologists (ASA) scoreASA scoreCohort studyPostoperative outcomesLumbar fusionBACKGROUND DATAAmerican CollegePatientsEvaluating the effect of growing patient numbers and changing data elements in the National Surgical Quality Improvement Program (NSQIP) database over the years: a study of posterior lumbar fusion outcomes
Shultz BN, Bovonratwet P, Ondeck NT, Ottesen TD, McLynn RP, Grauer JN. Evaluating the effect of growing patient numbers and changing data elements in the National Surgical Quality Improvement Program (NSQIP) database over the years: a study of posterior lumbar fusion outcomes. The Spine Journal 2018, 18: 1982-1988. PMID: 29649610, DOI: 10.1016/j.spinee.2018.03.016.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement ProgramNSQIP databaseERA groupPreoperative characteristicsPostoperative outcomesBlood transfusionSeptic shockOutcome studiesNational Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement ProgramQuality Improvement Program databaseSurgical Quality Improvement ProgramPosterior lumbar fusion surgeryLumbar fusion outcomesRetrospective cohort studyImprovement Program databaseYear of surgeryDeep vein thrombosisUrinary tract infectionLumbar fusion surgeryPostoperative day 30Number of patientsMultivariate Poisson regressionQuality Improvement ProgramPerioperative outcomesMissing data treatments matter: an analysis of multiple imputation for anterior cervical discectomy and fusion procedures
Ondeck NT, Fu MC, Skrip LA, McLynn RP, Cui JJ, Basques BA, Albert TJ, Grauer JN. Missing data treatments matter: an analysis of multiple imputation for anterior cervical discectomy and fusion procedures. The Spine Journal 2018, 18: 2009-2017. PMID: 29649614, DOI: 10.1016/j.spinee.2018.04.001.Peer-Reviewed Original ResearchConceptsSevere adverse eventsNational Surgical Quality Improvement ProgramAnterior cervical discectomyAdverse eventsPreoperative anemiaPreoperative hypoalbuminemiaPreoperative albuminCervical discectomyHospital readmissionAdverse outcomesComplete case analysisSurgical Quality Improvement ProgramAdverse outcome variablesOne-level ACDFPreoperative laboratory valuesBody mass indexFusion proceduresMultiple imputationLogistic regression analysisQuality Improvement ProgramPreoperative hematocritPostoperative outcomesRetrospective reviewMass indexLaboratory values
2015
Risk Factors for Blood Transfusion With Primary Posterior Lumbar Fusion
Basques BA, Anandasivam NS, Webb ML, Samuel AM, Lukasiewicz AM, Bohl DD, Grauer JN. Risk Factors for Blood Transfusion With Primary Posterior Lumbar Fusion. Spine 2015, 40: 1792-1797. PMID: 26165220, DOI: 10.1097/brs.0000000000001047.Peer-Reviewed Original ResearchConceptsPrimary posterior lumbar fusionPosterior lumbar fusionBlood transfusionLumbar fusionPostoperative outcomesRisk factorsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseDeep surgical site infectionShort-term postoperative outcomesQuality Improvement Program databasePosterior lumbar fusion surgeryRetrospective cohort studyImprovement Program databaseSurgical site infectionLumbar fusion surgeryAnesthesiologists classPostoperative complicationsPostoperative lengthPreoperative hematocritCohort studyPatient characteristicsPulmonary embolismBlood lossPulmonary disease